Isolated adrenocorticotropic hormone deficiency possibly caused by nivolumab in a metastatic melanoma patient

Journal of Dermatology

Volumn 44, Issue 3, 2017, Pages e13-e14

  Fujimura, Taku ^a   Kambayashi, Yumi ^a   Furudate, Sadanori ^a   Kakizaki, Aya ^a   Hidaka, Takanori ^a   Haga, Takahiro ^a   Hashimoto, Akira ^a   Morimoto, Ryo ^b   Aiba, Setsuya ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD163 ANTIGEN; CORTICOTROPIN; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; NIVOLUMAB; THYROTROPIN; TUMOR NECROSIS FACTOR; IMMUNOLOGICAL ANTINEOPLASTIC AGENT;

ACRAL LENTIGINOUS MELANOMA; AGED; BRAIN METASTASIS; CASE REPORT; CORTICOTROPIN DEFICIENCY; CUTANEOUS MELANOMA; CYBERKNIFE; HUMAN; HUMAN TISSUE; HYPOPITUITARISM; LETTER; MALE; METASTATIC MELANOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; SKIN NODULE; THYROTROPIN BLOOD LEVEL; CHEMICALLY INDUCED; DEFICIENCY; ENDOCRINE DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC DISORDER; HYPOGLYCEMIA; MELANOMA; METASTASIS; PATHOLOGY; SKIN TUMOR;

ADRENOCORTICOTROPIC HORMONE; AGED; ANTINEOPLASTIC AGENTS, IMMUNOLOGICAL; ENDOCRINE SYSTEM DISEASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC DISEASES, INBORN; HUMANS; HYPOGLYCEMIA; MALE; MELANOMA; NEOPLASM METASTASIS; NIVOLUMAB; SKIN NEOPLASMS;

EID: 84979231210     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/1346-8138.13532     Document Type: Letter

References (5)

1. Larkin J, Chiarion-Sileni V, Gonzalez R et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med 2015; 373: 23–34.
2. Fujimura T, Kakizaki A, Furudate S, Kambayashi Y, Aiba S. Tumor-associated macrophages in skin: how to treat their heterogeneity and plasticity. J Dermatol Sci 2016; 83: 167–73.
3. Van Gorp H, Delputte PL, Nauwynck HJ. Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy. Mol Immunol 2010; 47: 1650–1660.
4. Rumble JM, Huber AK, Krishnamoorthy G et al. Neutrophil-related factors as biomarkers in EAE and MS. J Exp Med 2015; 212: 23–35.
5. Ishikawa M, Oashi K. Case of hypophysitis caused by nivolumab. J Dermatol 2017; 44: 109–110.