Neural mechanisms linking social status and inflammatory responses to social stress

Social Cognitive and Affective Neuroscience

Volumn 11, Issue 6, 2016, Pages 915-922

  Muscatell, Keely A ^a,b   Dedovic, Katarina ^b,c   Slavich, George M ^d   Jarcho, Michael R ^d,e   Breen, Elizabeth C ^d   Bower, Julienne E ^b,d   Irwin, Michael R ^b,d   Eisenberger, Naomi I ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e LORAS COLLEGE   (United States)

Author keywords

Dorsomedial prefrontal cortex; fMRI; Inflammation; Interleukin 6; Stress; Subjective social status

Indexed keywords

ADOLESCENT; ADULT; BLOOD; FEMALE; HUMAN; HUMAN RELATION; INFLAMMATION; MENTAL STRESS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; PREFRONTAL CORTEX; SOCIAL CLASS; SOCIAL DOMINANCE; YOUNG ADULT;

ADOLESCENT; ADULT; FEMALE; HIERARCHY, SOCIAL; HUMANS; INFLAMMATION; INTERPERSONAL RELATIONS; MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; SOCIAL CLASS; STRESS, PSYCHOLOGICAL; YOUNG ADULT;

EID: 84979011058     PISSN: 17495016     EISSN: 17495024     Source Type: Journal    
DOI: 10.1093/scan/nsw025     Document Type: Article

References (50)

1. Adler, N.E., Boyce, T., Chesney, M.A., et al. (1994). Socioeconomic status and health: the challenge of the gradient. American Psychologist, 49, 15-24.
2. Adler, N.E., Epel, E.S., Castellazzo, G., Ickovics, J.R. (2000). Relationship of subjective and objective social status with psychological and physiological functioning: preliminary data in healthy, White women. Health Psychology, 19, 586-92.
3. Adolphs, R. (2010). What does the amygdala contribute to social cognition? Annals of the New York Academy of Sciences, 1191, 42-61.
4. Blanchard, D.C., Skai, R.R., McEwen, B., Weiss, S.M., Blanchard, R.J. (1993). Subordination stress: behavioral, brain, and neuroendocrine correlates. Behavioural Brain Research, 58, 113-21.
5. Brydon, L., Edwards, S., Mohamed-Ali, V., Steptoe, A. (2004). Socioeconomic status and stress-induced increases in interleukin- 6. Brain, Behavior, and Immunity, 18, 281-90.
6. Cunningham, W.A., Brosch, T. (2012). Motivational salience amygdala tuning from traits, needs, values, and goals. Current Directions in Psychological Science, 21, 54-9.
7. Derry, H.M., Fagundes, C.P., Andridge, R., Glaser, R., Malarkey, W.B., Kiecolt-Glaser, J.K. (2013). Lower subjective social status exaggerates interleukin-6 responses to a laboratory stressor. Psychoneuroendocrinology, 38, 2676-85.
8. Dickerson, S.S., Gable, S.L., Irwin, M.R., Aziz, N., Kemeny, M.E. (2009). Social-evaluative threat and proinflammatory cytokine regulation: an experimental laboratory investigation. Psychological Science, 20, 1237-44.
9. Eisenberger, N.I., Cole, S.W. (2012). Social neuroscience and health: neurophysiological mechanisms linking social ties with physical health. Nature Neuroscience, 15, 669-74.
10. Eisenberger, N.I., Inagaki, T.K., Muscatell, K.A., Haltom, K.E.B., Leary, M.R. (2011). The neural sociometer: a mechanism for translating interpersonal appraisals into state self-esteem. Journal of Cognitive Neuroscience, 23, 3448-55.
11. Fernald, R.D., Maruska, K.P. (2012). Social information changes the brain. Proceedings of the National Academy of Sciences of the United States of America, 109, 17194-9.
12. First, M.B., Gibbon, M., Spitzer, R.L., Williams, J.B.W. (1995). User's Guide for the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I, Version 2.0, Final Version). New York (NY): New York State Psychiatric Institute.
13. Ghazanfar, A.A., Santos, L.R. (2004). Primate brains in the wild: the sensory bases for social interactions. Nature Reviews Neuroscience, 5, 603-16.
14. Gianaros, P.J., Horenstein, J.A., Hariri, A.R., et al. (2008). Potential neural embedding of parental social standing. Social Cognitive and Affective Neuroscience, 3, 91-6.
15. Gianaros, P.J., Sheu, L.K. (2009). A review of neuroimaging studies of stressor-evoked blood pressure reactivity: emerging evidence for a brain-body pathway to coronary heart disease risk. NeuroImage, 47, 922-36.
16. Gruenewald, T.L., Kemeny, M.E., Aziz, N. (2006). Subjective social status moderates cortisol responses to social threat. Brain, Behavior, and Immunity, 20, 410-9.
17. Hansson, G.K. (2005). Inflammation, atherosclerosis, and coronary artery disease. New England Journal of Medicine, 352, 1685-95.
18. Hill, R.A., Dunbar, R.I.M. (2003). Social network size in humans. Human Nature, 14, 53-72.
19. Kemeny, M.E. (2009). Psychobiological responses to social threat: evolution of a psychological model in psychoneuroimmunology. Brain, Behavior, and Immunity, 23, 1-9.
20. Kessler, R.C. (1979). Stress, social status, and psychological distress. Journal of Health and Social Behavior, 20, 259-72.
21. Kollack-Walker, S., Watson, S.J., Akil, H. (1997). Social stress in hamsters: defeat activates specific neurocircuits within the brain. The Journal of Neuroscience, 17, 8842-55.
22. Kraus, M.W., Cote, S., Keltner, D. (2010). Social class, contextualism, and empathic accuracy. Psychological Science, 21, 1716-32.
23. Kraus, M.W., Keltner, D. (2009). Signs of socioeconomic status a thin-slicing approach. Psychological Science, 20, 99-106.
24. LeDoux, J.E., Iwata, J., Cicchetti, P., Reis, D.J. (1988). Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of fear. The Journal of Neurosceince, 8, 2517-29.
25. Lieberman, M.D. (2007). Social cognitive neuroscience: a review of core processes. Annual Review of Psychology, 58, 259-89.
26. Lieberman, M.D., Cunningham, W.A. (2009). Type I and Type II error concerns in fMRI research: re-balancing the scale. Social Cognitive and Affective Neuroscience, 4, 423-8.
27. Mauss, I.B., Levenson, R.W., McCarter, L., Wilhelm, F.H., Gross, J.J. (2005). The tie that binds? Coherence among emotion experience, behavior, and physiology. Emotion, 5, 175-90.
28. Miller, G.E., Chen, E., Fok, A.K., et al. (2009). Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling. Proceedings of the National Academy of Sciences, 106, 14716-21.
29. Miller, A.H., Maletic, V., Raison, C.L. (2009). Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biological Psychiatry, 65, 732-41.
30. Mitchell, J.P., Macrae, C.N., Banaji, M.R. (2005). Forming impressions of people versus inanimate objects: social-cognitive processing in the medial prefrontal cortex. NeuroImage, 26, 251-7.
31. Muscatell, K.A., Dedovic, K., Slavich, G.M., et al. (2015). Greater amygdala activity and dorsomedial prefrontal-amygdala coupling are associated with enhanced inflammatory responses to stress. Brain, Behavior, and Immunity, 43, 46-53.
32. Muscatell, K.A., Eisenberger, N.I. (2012). A social neuroscience perspective on stress and health. Social and Personality Psychology Compass, 6, 890-904.
33. Muscatell, K.A., Morelli, S.A., Falk, E.B., et al. (2012). Social status modulates neural activity in the mentalizing network. NeuroImage, 60, 1771-7.
34. Noble, K.G., McCandliss, B.D., Farah, M.J. (2007). Socioeconomic gradients predict individual differences in neurocognitive abilities. Developmental Science, 10, 464-80.
35. Ongur, D., Price, J.L. (2000). The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys, and humans. Cerebral Cortex, 10, 206-19.
36. Powell, N.D., Bailey, M.T., Mays, J.W., et al. (2009). Repeated social defeat activates dendritic cells and enhances toll-like receptor dependent cytokine secretion. Brain, Behavior, and Immunity, 23, 225-31.
37. Powell, N.D., Sloan, E.K., Bailey, M.T., Arevalo, J.M.G., Miller, G.E., Cole, S.W. (2013). Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via b-adrenergic induction of myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America, 110, 16574-9.
38. Preacher, K.J., Hayes, A.F. (2004). SPSS and SAS procedures for estimating indirect effects in simple meditational models. Behavioral Research Methods, 36, 717-31.
39. Preacher, K.J., Kelley, K. (2011). Effect size measures for mediation models: quantitative strategies for communicating indirect effects. Psychological Methods, 16, 93-115.
40. Robinson, O.J., Charney, D.R., Overstreet, C., Vytal, K., Grillon, C. (2012). The adaptive threat bias in anxiety: amygdala-dorsomedial prefrontal cortex coupling and aversive amplification. NeuroImage, 60, 523-9.
41. Rohleder, N., Schommer, N.C., Hellhammer, D.H., Engel, R., Kirschbaum, C. (2001). Sex differences in glucocorticoid sensitivity of proinflammatory cytokine production after psychosocial stress. Psychosomatic Medicine, 63, 966-72.
42. Sapolsky, R.M. (2005). The influence of social hierarchy on primate health. Science, 308, 648-52.
43. Slavich, G.M., Cole, S.W. (2013). The emerging field of human social genomics. Clinical Psychological Science, 1, 331-48.
44. Steptoe, A., Hamer, M., Chida, Y. (2007). The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain, Behavior, and Immunity, 21, 901-12.
45. Stroud, L.R., Salovey, P., Epel, E.S. (2002). Sex differences in stress responses: social rejection versus achievement stress. Biological Psychiatry, 52, 318-27.
46. Tung, J., Barreiro, L.B., Johnson, Z.P., et al. (2012). Social environment is associated with gene regulatory variation in the rhesus macaque immune system. Proceedings of the National Academy of Sciences of the United State of America, 109, 6490-5.
47. Wager, T.D., Barrett, L.F., Bliss-Moreau, E., et al. (2008). The neuroimaging of emotion. The Handbook of Emotion, 3, 249-71.
48. Wager, T.D., van Ast, V.A., Hughes, B.L., Davidson, M.L., Lindquist, M.A., Ochsner, K.N. (2009). Brain mediators of cardiovascular responses to social threat, Part II: prefrontalsubcortical pathways and relationship with anxiety. NeuroImage, 47, 836-51.
49. Wang, F., Kessels, H.W., Hu, H. (2014). The mouse that roared: neural mechanisms of a social hiearchy. Trends in Neurosciences, 37, 674-82.
50. Yan, H., Bonasio, R., Simola, D.F., Liebig, J., Berger, S.L., Reinberg, D. (2015). DNA methylation in social insects: how epigenetics can control behavior and longevity. Annual Review of Entomology, 60, 435-52.