Seeking harmony: Estimands and sensitivity analyses for confirmatory clinical trials

Clinical Trials

Volumn 13, Issue 4, 2016, Pages 456-458

  Mehrotra, Devan V ^a   Hemmings, Robert J ^b   Russek Cohen, Estelle ^c  

^a MERCK RESEARCH LABORATORIES   (United States)

^b MEDICINES AND HEALTHCARE PRODUCTS REGULATORY AGENCY   (United Kingdom)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Dropouts; estimand; International Conference on Harmonization E9; missing data; sensitivity analysis; trial planning

Indexed keywords

ANTIDIABETIC AGENT; HEMOGLOBIN A1C; PLACEBO; VACCINE;

ARTICLE; CLINICAL STUDY; CLINICAL TRIAL (TOPIC); CONFIRMATION BIAS; DECISION MAKING; DRUG EFFICACY; DRUG SAFETY; HUMAN; INFORMATION SEEKING; PLANNING; POLICY; PRACTICE GUIDELINE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; TELECONFERENCE; THERAPY EFFECT; CONSENSUS; DRUG APPROVAL; METHODOLOGY; PROCEDURES; STANDARDS;

CLINICAL TRIALS AS TOPIC; CONSENSUS; DATA INTERPRETATION, STATISTICAL; DRUG APPROVAL; GUIDELINES AS TOPIC; HUMANS; RESEARCH DESIGN;

EID: 84978976680     PISSN: 17407745     EISSN: 17407753     Source Type: Journal    
DOI: 10.1177/1740774516633115     Document Type: Article

References (6)

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