Neuronal endocytosis of anti-ganglioside antibodies: Implications for Guillain-Barré syndrome

Brain

Volumn 139, Issue 6, 2016, Pages 1622-1625

  Van Doorn, Pieter A ^a   Jacobs, Bart C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ECULIZUMAB; GANGLIOSIDE ANTIBODY; IMMUNOGLOBULIN; ANTIBODY; AUTOANTIBODY; GANGLIOSIDE;

CLINICAL FEATURE; COMPLEMENT ACTIVATION; ENDOCYTOSIS; GUILLAIN BARRE SYNDROME; HUMAN; NERVE ENDING; NEURONAL ENDOCYTOSIS; NONHUMAN; NOTE; PLASMAPHERESIS; PRIORITY JOURNAL; RETROGRADE NERVE FIBER TRANSPORT; SYSTEMIC CIRCULATION; NERVE CELL;

ANTIBODIES; AUTOANTIBODIES; ENDOCYTOSIS; GANGLIOSIDES; GUILLAIN-BARRE SYNDROME; HUMANS; NEURONS;

EID: 84978878306     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aww078     Document Type: Note

References (10)

1. Cao-Lormeau VM, Blake A, Mons S, Lastere S, Vanhomwegen J, Dub T et al. Guillain-Barré syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet online February 29, 2016
2. van den Berg B, Walgaard C, Drenthen J, Fokke C, Jacobs BC, van Doorn PA, Guillain-Barre syndrome: pathogenesis, diagnosis, treatment and prognosis. Nat Rev Neurol 2014; 10: 469-82.
3. Cunningham M. MR, Meehan G, Barrie J, Yao D, Halstead S, Willison H, Anti-ganglioside antibodies are removed from the circulation by neural endocytosis. Brain 2016; 139: 1657-65.
4. Wakerley BR, Yuki N. Mimics and chameleons in Guillain-Barre and Miller Fisher syndromes. Pract Neurol 2015; 15: 90-9.
5. Willison HJ. The immunobiology of Guillain-Barre syndromes. JPeripherNervSyst 2005; 10: 94-112.
6. Yuki N. Guillain-Barre syndrome and antiganglioside antibodies: a clinician-scientist's journey. Proc Jpn Acad Ser B Phys Biol Sci 2012; 88: 299-326.
7. Kusunoki S, Kaida K. Antibodies against ganglioside complexes in Guillain-Barre syndrome and related disorders. J Neurochem 2011; 116: 828-32.
8. Greenshields KN, Halstead SK, Zitman FM, Rinaldi S, Brennan KM, O'Leary C, et al. The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice. J Clin Invest 2009; 119: 595-610.
9. Fewou SN, Rupp A, Nickolay LE, Carrick K, Greenshields KN, Pediani J, et al. Antiganglioside antibody internalization attenuates motor nerve terminal injury in a mouse model of acute motor axonal neuropathy. J Clin Invest 2012; 122: 1037-51.
10. Massaad CA, Zhang G, Pillai L, Azhdarinia A, Liu W, Sheikh KA. Fluorescently-tagged anti-ganglioside antibody selectively identifies peripheral nerve in living animals. Sci Rep 2015; 5: 15766.