Adverse childhood experiences are associated with irritable bowel syndrome and gastrointestinal symptom severity

Neurogastroenterology and Motility

Volumn 28, Issue 8, 2016, Pages 1252-1260

  Park, S H ^a   Videlock, E J ^a   Shih, W ^a   Presson, A P ^b   Mayer, E A ^a   Chang, L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

abuse; adverse childhood experiences; early life trauma; early life trauma inventory; irritable bowel syndrome

Indexed keywords

ABDOMINAL PAIN; ADULT; ADVERSE CHILDHOOD EXPERIENCES QUESTIONNAIRE; ANXIETY DISORDER; ARTICLE; CHILD ABUSE; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; EARLY LIFE STRESS; EARLY TRAUMA INVENTORY SELF REPORT SHORT FORM SCORE; EMOTIONAL ABUSE; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; PHYSICAL ABUSE; PREVALENCE; PRIORITY JOURNAL; SEXUAL ABUSE; STRESS ASSESSMENT; VALIDITY;

EID: 84978877472     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12826     Document Type: Article

References (36)

1. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006; 130: 1480–91.
2. Chitkara DK, van Tilburg MA, Blois-Martin N, Whitehead WE. Early life risk factors that contribute to irritable bowel syndrome in adults: a systematic review. Am J Gastroenterol 2008; 103: 765–74.
3. Drossman DA, Leserman J, Nachman G, Li ZM, Gluck H, Toomey TC, Mitchell CM. Sexual and physical abuse in women with functional or organic gastrointestinal disorders. Ann Intern Med 1990; 113: 828–33.
4. Bradford K, Shih W, Videlock EJ, Presson AP, Naliboff BD, Mayer EA, Chang L. Association between early adverse life events and irritable bowel syndrome. Clin Gastroenterol Hepatol 2012; 10: 385–90 e1-3.
5. Talley NJ, Fett SL, Zinsmeister AR, Melton LJ. Gastrointestinal tract symptoms and self-reported abuse: a population-based study. Gastroenterology 1994; 107: 1040–9.
6. Halland M, Almazar A, Lee R, Atkinson E, Larson J, Talley NJ, Saito Y. A case-control study of childhood trauma in the development of irritable bowel syndrome. Neurogastroenterol Motil 2014; 26: 990–8.
7. Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, Koss MP, Marks JS. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med 1998; 14: 245–58.
8. Centers for Disease Control and Prevention. Behavioral Risk Factor Surveillance System. Available from: http://www.cdc.gov/brfss/index.html (accessed 2015 June, 17).
9. Gilbert LK, Breiding MJ, Merrick MT, Thompson WW, Ford DC, Dhingra SS, Parks SE. Childhood adversity and adult chronic disease: an update from ten states and the District of Columbia, 2010. Am J Prev Med 2015; 48: 345–9.
10. Kagi R, Regala D. Translating the Adverse Childhood Experiences (ACE) Study into public policy: progress and possibility in Washington State. J Prev Interv Community 2012; 40: 271–7.
11. Becker-Blease KA, Freyd JJ. Research participants telling the truth about their lives: the ethics of asking and not asking about abuse. Am Psychol 2006; 61: 218–26.
12. Halpert A, Dalton CB, Palsson O, MOrris C, Hu Y, Bangdiwala S, Hankins J, Norton N et al. What patients know about irritable bowel syndrome (IBS) and what they would like to know. National Survey on Patient Educational Needs in IBS and development and validation of the Patient Educational Needs Questionnaire (PEQ). Am J Gastroenterol 2007; 102: 1972–82.
13. Palsson OS, Whitehead WE. Psychological treatments in functional gastrointestinal disorders: a primer for the gastroenterologist. Clin Gastroenterol Hepatol 2013; 11: 208–16; quiz e22-3.
14. Craske MG, Wolitzky-Taylor KB, Labus J, Wu S, Frese M, Mayer EA, Naliboff BD. A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations. Behav Res Ther 2011; 49: 413–21.
15. Sikkema KJ, Ranby KW, Meade CS, Hansen NB, Wilson PA, Kochman A. Reductions in traumatic stress following a coping intervention were mediated by decreases in avoidant coping for people living with HIV/AIDS and childhood sexual abuse. J Consult Clin Psychol 2013; 81: 274–83.
16. Bremner JD, Bolus R, Mayer EA. Psychometric properties of the Early Trauma Inventory-Self Report. J Nerv Ment Dis 2007; 195: 211–8.
17. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361–70.
18. Kroenke K, Spitzer RL, Williams JB. The PHQ-15: validity of a new measure for evaluating the severity of somatic symptoms. Psychosom Med 2002; 64: 258–66.
19. Labus JS, Bolus R, Chang L, Wiklund I, Naesdal J, Mayer EA, Naliboff BD. The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale. Aliment Pharmacol Ther 2004; 20: 89–97.
20. Knight JR, Locke III GR, Zinsmeister AR, Schleck CD, Talley NJ. Family history of mental illness or alcohol abuse and the irritable bowel syndrome. J Psychosom Res 2015; 78: 237–41.
21. Koloski NA, Talley NJ, Boyce PM. A history of abuse in community subjects with irritable bowel syndrome and functional dyspepsia: the role of other psychosocial variables. Digestion 2005; 72: 86–96.
22. Saito YA, Petersen GM, Larson JJ, Atkinson EJ, Fridley BL, de Andrade M, Locke GR 3rd, Zimmerman JM et al. Familial aggregation of irritable bowel syndrome: a family case-control study. Am J Gastroenterol 2010; 105: 833–41.
23. Walker EA, Katon WJ, Jemelka RP, Roy-Bryne PP. Comorbidity of gastrointestinal complaints, depression, and anxiety in the Epidemiologic Catchment Area (ECA) Study. Am J Med 1992; 92: 26S–30S.
24. Levy RL. Exploring the intergenerational transmission of illness behavior: from observations to experimental intervention. Ann Behav Med 2011; 41: 174–82.
25. Ali A, Toner BB, Stuckless N, Gallop R, Diamant NE, Gould MI, Vidins EI. Emotional abuse, self-blame, and self-silencing in women with irritable bowel syndrome. Psychosom Med 2000; 62: 76–82.
26. White DL, Savas LS, Daci K, Elserag R, Graham DP, Fitzgerald SJ, Smith SL, Tan G et al. Trauma history and risk of the irritable bowel syndrome in women veterans. Aliment Pharmacol Ther 2010; 32: 551–61.
27. Ringel Y, Drossman DA, Leserman JL, Suyenobu BY, Wilber K, Lin W, Whitehead WE, Naliboff BD et al. Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an fMRI study. Gastroenterology 2008; 134: 396–404.
28. Ringel Y, Drossman DA, Turkington TG, Bradshaw B, Hawk TC, Bangdiwala S, Coleman RE, Whitehead WE. Regional brain activation in response to rectal distension in patients with irritable bowel syndrome and the effect of a history of abuse. Dig Dis Sci 2003; 48: 1774–81.
29. Gupta A, Kilpatrick L, Labus J, Tillisch K, Braun A, Hong JY, Ashe-McNalley C, Naliboff B et al. Early adverse life events and resting state neural networks in patients with chronic abdominal pain: evidence for sex differences. Psychosom Med 2014; 76: 404–12.
30. Seeley W, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 2007; 27: 2349–56.
31. Talley NJ, Boyce PM, Jones M. Is the association between irritable bowel syndrome and abuse explained by neuroticism? A population based study. Gut 1998; 42: 47–53.
32. Halpert A, Godena E. Irritable bowel syndrome patients' perspectives on their relationships with healthcare providers. Scand J Gastroenterol 2011; 46: 823–30.
33. Stewart M, Brown JB, Donner A, McWhinney IR, Oates J, Weston WW, Jordan J. The impact of patient-centered care on outcomes. J Fam Pract 2000; 49: 796–804.
34. Creed F, Guthrie E, Ratcliffe J, Fernandes L, Rigby C, Tomenson B, Read N, Thompson DG. Reported sexual abuse predicts impaired functioning but a good response to psychological treatments in patients with severe irritable bowel syndrome. Psychosom Med 2005; 67: 490–9.
35. Drossman DA, Toner BB, Whitehead WE, Diamant NE, Dalton CB, Duncan S, Emmott S, Proffitt V et al. Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. Gastroenterology 2003; 125: 19–31.
36. Lackner JM, Jaccard J, Krasner SS, Katz LA, Gudleski GD, Blanchard EB. How does cognitive behavior therapy for irritable bowel syndrome work? A mediational analysis of a randomized clinical trial. Gastroenterology 2007; 133: 433–44.