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Volumn 18, Issue 8, 2016, Pages

The ADAPTABLE Trial and Aspirin Dosing in Secondary Prevention for Patients with Coronary Artery Disease

Author keywords

Aspirin; Coronary artery disease; Myocardial infarction; Secondary prevention

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT;

EID: 84978705086     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-016-0749-2     Document Type: Review
Times cited : (54)

References (38)
  • 1
    • 84922381210 scopus 로고    scopus 로고
    • Heart disease and stroke statistics—2015 update: a report from the American Heart Association
    • PID: 25520374, The most recent statistics issued by the American Heart Association indicate the high prevalence of coronary heart disease and the wide variation in aspirin treatment across the US
    • Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics—2015 update: a report from the American Heart Association. Circulation. 2015;131(4):e29–322. The most recent statistics issued by the American Heart Association indicate the high prevalence of coronary heart disease and the wide variation in aspirin treatment across the US.
    • (2015) Circulation , vol.131 , Issue.4 , pp. e29-e322
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 2
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
    • PID: 1948221
    • Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373(9678):1849–60.
    • (2009) Lancet , vol.373 , Issue.9678 , pp. 1849-1860
    • Baigent, C.1    Blackwell, L.2    Collins, R.3
  • 3
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists’ Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. Br Med J. 2002;324(7329):71–86.
    • (2002) Br Med J , vol.324 , Issue.7329 , pp. 71-86
    • Antithrombotic Trialists’ Collaboration1
  • 4
    • 0023805341 scopus 로고
    • Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group
    • ISIS-2 Investigators. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet. 1988;2(8607):349–60.
    • (1988) Lancet , vol.2 , Issue.8607 , pp. 349-360
    • ISIS-2 Investigators1
  • 5
    • 84978763944 scopus 로고    scopus 로고
    • Statistical Brief #179
    • Soni A. Aspirin use among the adult U.S. noninstitutionalized population, with and without indicators of heart disease, 2005. Statistical Brief #179. Rockville: Agency for Healthcare Research and Quality; 2007. http://www.meps.ahrq.gov/mepsweb/data_files/publications/st179/stat179.pdf.
    • (2005) Rockville: Agency for Healthcare Research and Quality , pp. 2007
  • 6
    • 4644289299 scopus 로고    scopus 로고
    • Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • COI: 1:CAS:528:DC%2BD2cXptV2msLo%3D, PID: 1538347
    • Patrono C, Coller B, Fitzgerald GA, et al. Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(3 Suppl):234s–64s.
    • (2004) Chest , vol.126 , pp. 234s-264s
    • Patrono, C.1    Coller, B.2    Fitzgerald, G.A.3
  • 7
    • 0141919739 scopus 로고    scopus 로고
    • Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study
    • COI: 1:CAS:528:DC%2BD3sXns1Cgu78%3D, PID: 1450418
    • Peters RJ, Mehta SR, Fox KA, et al. Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study. Circulation. 2003;108(14):1682–7.
    • (2003) Circulation , vol.108 , Issue.14 , pp. 1682-1687
    • Peters, R.J.1    Mehta, S.R.2    Fox, K.A.3
  • 8
    • 56349111187 scopus 로고    scopus 로고
    • Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the BRAVO Trial)
    • COI: 1:CAS:528:DC%2BD1cXhtlCrtbbE, PID: 1899314
    • Aronow HD, Califf RM, Harrington RA, et al. Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the BRAVO Trial). Am J Cardiol. 2008;102(10):1285–90.
    • (2008) Am J Cardiol , vol.102 , Issue.10 , pp. 1285-1290
    • Aronow, H.D.1    Califf, R.M.2    Harrington, R.A.3
  • 9
    • 0027958181 scopus 로고
    • Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury
    • COI: 1:CAS:528:DyaK2cXjtFGns7w%3D, PID: 827398
    • Lee M, Cryer B, Feldman M. Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury. Ann Intern Med. 1994;120(3):184–9.
    • (1994) Ann Intern Med , vol.120 , Issue.3 , pp. 184-189
    • Lee, M.1    Cryer, B.2    Feldman, M.3
  • 10
    • 84911214755 scopus 로고    scopus 로고
    • Contemporary patterns of discharge aspirin dosing after acute myocardial infarction in the United States: results from the National Cardiovascular Data Registry (NCDR)
    • PID: 25116897, This study shows the variation in aspirin dosing patterns across the United States in patients post- acute coronary syndrom
    • Hall HM, de Lemos JA, Enriquez JR, et al. Contemporary patterns of discharge aspirin dosing after acute myocardial infarction in the United States: results from the National Cardiovascular Data Registry (NCDR). Circ Cardiovasc Qual Outcomes. 2014;7(5):701–7. This study shows the variation in aspirin dosing patterns across the United States in patients post- acute coronary syndrome.
    • (2014) Circ Cardiovasc Qual Outcomes , vol.7 , Issue.5 , pp. 701-707
    • Hall, H.M.1    de Lemos, J.A.2    Enriquez, J.R.3
  • 11
    • 34248352504 scopus 로고    scopus 로고
    • Aspirin dose for the prevention of cardiovascular disease: a systematic review
    • COI: 1:CAS:528:DC%2BD2sXltFGitLw%3D, PID: 1748896
    • Campbell CL, Smyth S, Montalescot G, et al. Aspirin dose for the prevention of cardiovascular disease: a systematic review. JAMA. 2007;297(18):2018–24.
    • (2007) JAMA , vol.297 , Issue.18 , pp. 2018-2024
    • Campbell, C.L.1    Smyth, S.2    Montalescot, G.3
  • 12
    • 79952061809 scopus 로고    scopus 로고
    • Aspirin: a historical and contemporary therapeutic overview
    • PID: 2134359
    • Fuster V, Sweeny JM. Aspirin: a historical and contemporary therapeutic overview. Circulation. 2011;123(7):768–78.
    • (2011) Circulation , vol.123 , Issue.7 , pp. 768-778
    • Fuster, V.1    Sweeny, J.M.2
  • 13
    • 0023867360 scopus 로고
    • Secondary prevention of vascular disease by prolonged antiplatelet treatment
    • Antiplatelet Trialists’ Collaboration. Secondary prevention of vascular disease by prolonged antiplatelet treatment. Br Med J. 1988;296(6618):320–31.
    • (1988) Br Med J , vol.296 , Issue.6618 , pp. 320-331
    • Antiplatelet Trialists’ Collaboration1
  • 14
    • 0020692577 scopus 로고
    • Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man
    • COI: 1:CAS:528:DyaL3sXhslakurs%3D, PID: 633804
    • FitzGerald GA, Oates JA, Hawiger J, et al. Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man. J Clin Invest. 1983;71(3):676–88.
    • (1983) J Clin Invest , vol.71 , Issue.3 , pp. 676-688
    • FitzGerald, G.A.1    Oates, J.A.2    Hawiger, J.3
  • 15
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists’ Collaboration. Collaborative overview of randomised trials of antiplatelet therapy prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Br Med J. 1994;308:81–106.
    • (1994) Br Med J , vol.308 , pp. 81-106
    • Antiplatelet Trialists’ Collaboration1
  • 16
    • 0026075195 scopus 로고
    • Two year Cottbus reinfarction study with 30 mg aspirin per day
    • COI: 1:STN:280:DyaK383ivVymsA%3D%3
    • Hoffman W, Förster W. Two year Cottbus reinfarction study with 30 mg aspirin per day. Prostaglandins Leukot Essent Fat Acids. 1991;44(3):159–69.
    • (1991) Prostaglandins Leukot Essent Fat Acids , vol.44 , Issue.3 , pp. 159-169
    • Hoffman, W.1    Förster, W.2
  • 17
    • 0024467861 scopus 로고
    • Acetylsalicylic acid 100 mg and 1000 mg daily in acute myocardial infarction suspects: a placebo-controlled trial
    • COI: 1:STN:280:DyaK3c%2FjvFWisg%3D%3D, PID: 268150
    • Husted SE, Kraemmer Nielsen H, Krusell LR, et al. Acetylsalicylic acid 100 mg and 1000 mg daily in acute myocardial infarction suspects: a placebo-controlled trial. J Intern Med. 1989;226(5):303–10.
    • (1989) J Intern Med , vol.226 , Issue.5 , pp. 303-310
    • Husted, S.E.1    Kraemmer Nielsen, H.2    Krusell, L.R.3
  • 18
    • 0037106948 scopus 로고    scopus 로고
    • Seeking the optimal aspirin dose in acute coronary syndromes
    • PID: 1223108
    • Kong DF, Hasselblad V, Kandzari DE, et al. Seeking the optimal aspirin dose in acute coronary syndromes. Am J Cardiol. 2002;90(6):622–5.
    • (2002) Am J Cardiol , vol.90 , Issue.6 , pp. 622-625
    • Kong, D.F.1    Hasselblad, V.2    Kandzari, D.E.3
  • 19
    • 37649002657 scopus 로고    scopus 로고
    • Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis
    • COI: 1:CAS:528:DC%2BD1cXlt1aluw%3D%3D, PID: 1818707
    • Berger JS, Brown DL, Becker RC. Low-dose aspirin in patients with stable cardiovascular disease: a meta-analysis. Am J Med. 2008;121(1):43–9.
    • (2008) Am J Med , vol.121 , Issue.1 , pp. 43-49
    • Berger, J.S.1    Brown, D.L.2    Becker, R.C.3
  • 20
    • 33645861080 scopus 로고    scopus 로고
    • Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events
    • COI: 1:CAS:528:DC%2BD28Xjs12gsLk%3D, PID: 1653161
    • Bhatt DL, Fox KAA, Hacke W, et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. NEJM. 2006;354(16):1706–17.
    • (2006) NEJM , vol.354 , Issue.16 , pp. 1706-1717
    • Bhatt, D.L.1    Fox, K.A.A.2    Hacke, W.3
  • 21
    • 0037145863 scopus 로고    scopus 로고
    • Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial
    • COI: 1:CAS:528:DC%2BD38XoslOksL0%3D, PID: 1243525
    • Steinhubl SR, Berger PB, Mann 3rd JT, et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA. 2002;288(19):2411–20.
    • (2002) JAMA , vol.288 , Issue.19 , pp. 2411-2420
    • Steinhubl, S.R.1    Berger, P.B.2    Mann, J.T.3
  • 22
    • 9244248078 scopus 로고    scopus 로고
    • A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction
    • PID: 862372
    • O’Connor CM, Meese RB, McNulty S, et al. A randomized factorial trial of reperfusion strategies and aspirin dosing in acute myocardial infarction. Am J Cardiol. 1996;77(10):791–7.
    • (1996) Am J Cardiol , vol.77 , Issue.10 , pp. 791-797
    • O’Connor, C.M.1    Meese, R.B.2    McNulty, S.3
  • 23
    • 77956290748 scopus 로고    scopus 로고
    • Dose comparisons of clopidogrel and aspirin in acute coronary syndromes
    • The CURRENT-OASIS 7 Investigators. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. NEJM. 2010;363(10):930–42.
    • (2010) NEJM , vol.363 , Issue.10 , pp. 930-942
    • The CURRENT-OASIS 7 Investigators1
  • 24
    • 77958005516 scopus 로고    scopus 로고
    • Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial
    • COI: 1:CAS:528:DC%2BC3cXht1KrsbbE, PID: 2081728
    • Mehta SR, Tanguay JF, Eikelboom JW, et al. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet. 2010;376(9748):1233–43.
    • (2010) Lancet , vol.376 , Issue.9748 , pp. 1233-1243
    • Mehta, S.R.1    Tanguay, J.F.2    Eikelboom, J.W.3
  • 25
    • 84937694667 scopus 로고    scopus 로고
    • Association of discharge aspirin dose with outcomes after acute myocardial infarction: insights from the treatment with ADP receptor inhibitors: longitudinal assessment of treatment patterns and events after acute coronary syndrome (TRANSLATE-ACS) study
    • Xian Y, Wang TY, McCoy LA, et al. Association of discharge aspirin dose with outcomes after acute myocardial infarction: insights from the treatment with ADP receptor inhibitors: longitudinal assessment of treatment patterns and events after acute coronary syndrome (TRANSLATE-ACS) study. Circulation 2015;132(3):174–81.
    • (2015) Circulation , vol.132 , Issue.3 , pp. 174-181
    • Xian, Y.1    Wang, T.Y.2    McCoy, L.A.3
  • 26
    • 84892735573 scopus 로고    scopus 로고
    • Discharge aspirin dose and clinical outcomes in patients with acute coronary syndromes treated with prasugrel versus clopidogrel: an analysis from the TRITON–TIMI 38 study (Trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel–thrombolysis in myocardial infarction 38)
    • COI: 1:CAS:528:DC%2BC2cXhsVymtrs%3D, PID: 2414067
    • Kohli P, Udell JA, Murphy SA, et al. Discharge aspirin dose and clinical outcomes in patients with acute coronary syndromes treated with prasugrel versus clopidogrel: an analysis from the TRITON–TIMI 38 study (Trial to assess improvement in therapeutic outcomes by optimizing platelet inhibition with prasugrel–thrombolysis in myocardial infarction 38). J Am Coll Cardiol. 2014;63(3):225–32.
    • (2014) J Am Coll Cardiol , vol.63 , Issue.3 , pp. 225-232
    • Kohli, P.1    Udell, J.A.2    Murphy, S.A.3
  • 27
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • COI: 1:CAS:528:DC%2BD1MXhtFaltL%2FJ, PID: 1971784
    • Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. NEJM. 2009;361(11):1045–57.
    • (2009) NEJM , vol.361 , Issue.11 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3
  • 28
    • 79955766404 scopus 로고    scopus 로고
    • Explaining the unexpected: insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany “Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified
    • COI: 1:CAS:528:DC%2BC3MXns1Slu78%3D, PID: 2139438
    • Ohman EM, Roe MT. Explaining the unexpected: insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany “Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified”. Thromb Haemost. 2011;105(5):763–5.
    • (2011) Thromb Haemost , vol.105 , Issue.5 , pp. 763-765
    • Ohman, E.M.1    Roe, M.T.2
  • 29
    • 80051550924 scopus 로고    scopus 로고
    • Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial
    • COI: 1:CAS:528:DC%2BC3MXpslGisrc%3D, PID: 2170906
    • Mahaffey KW, Wojdyla DM, Carroll K, et al. Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial. Circulation. 2011;124(5):544–54.
    • (2011) Circulation , vol.124 , Issue.5 , pp. 544-554
    • Mahaffey, K.W.1    Wojdyla, D.M.2    Carroll, K.3
  • 30
    • 0027240597 scopus 로고
    • An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction
    • The GUSTO investigators. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med. 1993;329(10):673–82.
    • (1993) N Engl J Med , vol.329 , Issue.10 , pp. 673-682
    • The GUSTO investigators1
  • 31
    • 0023258694 scopus 로고
    • Thrombolysis in Myocardial Infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge
    • COI: 1:STN:280:DyaL2s3ksVOktg%3D%3D, PID: 310976
    • Chesebro JH, Knatterud G, Roberts R, et al. Thrombolysis in Myocardial Infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge. Circulation. 1987;76(1):142–54.
    • (1987) Circulation , vol.76 , Issue.1 , pp. 142-154
    • Chesebro, J.H.1    Knatterud, G.2    Roberts, R.3
  • 32
    • 79959550517 scopus 로고    scopus 로고
    • Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the bleeding academic research consortium
    • PID: 2167024
    • Mehran R, Rao SV, Bhatt DL, et al. Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the bleeding academic research consortium. Circulation. 2011;123(23):2736–47.
    • (2011) Circulation , vol.123 , Issue.23 , pp. 2736-2747
    • Mehran, R.1    Rao, S.V.2    Bhatt, D.L.3
  • 33
    • 84922235633 scopus 로고    scopus 로고
    • Use of low-dose aspirin as secondary prevention of atherosclerotic cardiovascular disease in US adults (from the National Health Interview Survey, 2012)
    • COI: 1:CAS:528:DC%2BC2MXitlOksrc%3D, PID: 2567063
    • Fang J, George MG, Gindi RM, et al. Use of low-dose aspirin as secondary prevention of atherosclerotic cardiovascular disease in US adults (from the National Health Interview Survey, 2012). Am J Cardiol. 2015;115(7):895–900.
    • (2015) Am J Cardiol , vol.115 , Issue.7 , pp. 895-900
    • Fang, J.1    George, M.G.2    Gindi, R.M.3
  • 34
    • 84862119222 scopus 로고    scopus 로고
    • European guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts)
    • COI: 1:CAS:528:DC%2BC38XhtVeitr3P, PID: 2255521
    • Perk J, De Backer G, Gohlke H, et al. European guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J. 2012;33(13):1635–701.
    • (2012) Eur Heart J , vol.33 , Issue.13 , pp. 1635-1701
    • Perk, J.1    De Backer, G.2    Gohlke, H.3
  • 35
    • 82355175158 scopus 로고    scopus 로고
    • AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation
    • PID: 2205293
    • Smith SC, Benjamin EJ, Bonow RO, et al. AHA/ACCF secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 update: a guideline from the American Heart Association and American College of Cardiology Foundation. Circulation. 2011;124(22):2458–73.
    • (2011) Circulation , vol.124 , Issue.22 , pp. 2458-2473
    • Smith, S.C.1    Benjamin, E.J.2    Bonow, R.O.3
  • 36
    • 79955772062 scopus 로고    scopus 로고
    • Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified
    • COI: 1:CAS:528:DC%2BC3MXns1Slurc%3D, PID: 2138407
    • Serebruany VL. Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified. Thromb Haemost. 2011;105(5):752–9.
    • (2011) Thromb Haemost , vol.105 , Issue.5 , pp. 752-759
    • Serebruany, V.L.1
  • 37
    • 84978759024 scopus 로고    scopus 로고
    • ADAPTABLE Home- Adaptable. Retrieved from. This study is a large, multicenter randomized clinical trial addressing optimal aspirin dosing in secondary prevention in patients with cardiovascular diseas
    • ADAPTABLE Home- Adaptable. Retrieved from http://theaspirinstudy.org. This study is a large, multicenter randomized clinical trial addressing optimal aspirin dosing in secondary prevention in patients with cardiovascular disease.
  • 38
    • 0037906337 scopus 로고    scopus 로고
    • Aspirin and clopidogrel in acute coronary syndromes: therapeutic insights from the CURE study
    • COI: 1:CAS:528:DC%2BD3sXkvFOjt7c%3D, PID: 1276795
    • Jneid H, Bhatt DL, Corti R, et al. Aspirin and clopidogrel in acute coronary syndromes: therapeutic insights from the CURE study. Arch Intern Med. 2003;163(10):1145–53.
    • (2003) Arch Intern Med , vol.163 , Issue.10 , pp. 1145-1153
    • Jneid, H.1    Bhatt, D.L.2    Corti, R.3


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