Alpha-actin-2 mutations in Chinese patients with a non-syndromatic thoracic aortic aneurysm

BMC Medical Genetics

Volumn 17, Issue 1, 2016, Pages

  Ke, Tie ^a   Han, Meng ^a   Zhao, Miao ^a   Wang, Qing Kenneth ^a,b   Zhang, Huazhi ^a   Zhao, Yuanyuan ^a   Ruan, Xinlong ^c   Li, Hui ^a   Xu, Chengqi ^a   Sun, Tucheng ^c  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b LERNER RESEARCH INSTITUTE   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

ACTA2; Chinese population; Gene mutation; Thoracic aortic aneurysm and dissection

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; MYOSIN HEAVY CHAIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; ACTA2 PROTEIN, HUMAN; ACTIN; DNA;

ACTA2 GENE; ADULT; AORTA DISSECTING ANEURYSM; ARTICLE; CHINESE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; GENETIC SCREENING; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MISSENSE MUTATION; MUTATION RATE; MUTATIONAL ANALYSIS; MUTATOR GENE; MYH11 GENE; PREVALENCE; SMAD3 GENE; TGFBR1 GENE; TGFBR2 GENE; THORACIC AORTA ANEURYSM; AGED; AMINO ACID SEQUENCE; ANIMAL; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; CHEMISTRY; CHILD; CHINA; DNA MUTATIONAL ANALYSIS; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PEDIGREE; PHASE TRANSITION; SEQUENCE ALIGNMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

ACTINS; ADULT; AGED; AMINO ACID SEQUENCE; ANIMALS; AORTIC ANEURYSM, THORACIC; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHILD; CHINA; COHORT STUDIES; DNA; DNA MUTATIONAL ANALYSIS; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PEDIGREE; PHASE TRANSITION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ALIGNMENT;

EID: 84978654517     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/s12881-016-0310-6     Document Type: Article

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