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1
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74349097845
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Strategies to reduce early morbidity and mortality in adults receiving antiretroviral therapy in resource-limited settings
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Jan
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S.D.Lawn, A.D.Harries, R.Wood Strategies to reduce early morbidity and mortality in adults receiving antiretroviral therapy in resource-limited settings. Curr Opinion HIV AIDS. 2010 Jan;5(1):18–26. doi:10.1097/COH.0b013e328333850f.
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(2010)
Curr Opinion HIV AIDS
, vol.5
, Issue.1
, pp. 18-26
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Lawn, S.D.1
Harries, A.D.2
Wood, R.3
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2
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84860524400
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Tenofovir nephrotoxicity: 2011 update
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B.Fernandez-Fernandez, A.B.Montoya-Ferrer, M.D.Sanz, et al. Tenofovir nephrotoxicity: 2011 update. AIDS Res Treat. 2011;2011:1–11. • This paper exposes the pathologic mechanisms of tubulopathy associated with tenofovir, having them categorised into acute and chronic conditions.
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(2011)
AIDS Res Treat
, vol.2011
, pp. 1-11
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Fernandez-Fernandez, B.1
Montoya-Ferrer, A.B.2
Sanz, M.D.3
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3
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79951983194
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Ritonavir-Induced acute kidney injury: kidney biopsy findings and review of literature
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Feb
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T.Shafi, M.J.Choi, L.C.Racussen, et al. Ritonavir-Induced acute kidney injury: kidney biopsy findings and review of literature. Clin Nephrol. 2011 Feb;75(01):60–64.•• This paper discusses evidence of kidney injury associated with ritonavir, particularly the tubulopathy. The evidence constitutes the rise of SeCr to higher than normal levels, which drops only when RTV is withdrawn.
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(2011)
Clin Nephrol
, vol.75
, Issue.1
, pp. 60-64
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Shafi, T.1
Choi, M.J.2
Racussen, L.C.3
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6
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77956817906
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Tenofovir-associated renal dysfunction in clinical practice: an observational cohort from western India
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Jan-Jun
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K.K.Patel, A.K.Patel, J.K.Patel. Tenofovir-associated renal dysfunction in clinical practice: an observational cohort from western India. Indian J Sex Transm Dis. 2010 Jan-Jun;31(1):30–34.•• In the cohort, the researchers observed mild and moderate renal impairment in patients who received TDF based regimens. They observed a greater risk of renal impairment in patients receiving a ritonavir-boosted protease inhibitor.
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(2010)
Indian J Sex Transm Dis
, vol.31
, Issue.1
, pp. 30-34
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Patel, K.K.1
Patel, A.K.2
Patel, J.K.3
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7
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84879469666
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Impact of a tenofovira disoproxil fumarate plus ritonavir-boosted protease inhibitor-based regimen on renal function in HIV-infected individuals: a prospective, multicentre study
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Y.Cao, Y.Han, J.Xie, et al. Impact of a tenofovira disoproxil fumarate plus ritonavir-boosted protease inhibitor-based regimen on renal function in HIV-infected individuals: a prospective, multicentre study. BMC Infect Dis. 2013;13(1):301.•• There was greater risk of renal impairment in patients who received TDF with a ritonavir-boosted protease inhibitor. The authors recommended closer monitoring of patients taking a regimen with these medicines.
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(2013)
BMC Infect Dis
, vol.13
, Issue.1
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Cao, Y.1
Han, Y.2
Xie, J.3
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8
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35448960410
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Gender differences in kidney function
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I.Sabolic, A.R.Asif, W.E.Budach, et al. Gender differences in kidney function. Pflugers Arch. 2007;3(455):397–429.
-
(2007)
Pflugers Arch
, vol.3
, Issue.455
, pp. 397-429
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Sabolic, I.1
Asif, A.R.2
Budach, W.E.3
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9
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33749531758
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Mechanism of active renal tubular efflux of tenofovir
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A.S.Ray, T.Cihlar, K.L.Robinson, et al. Mechanism of active renal tubular efflux of tenofovir. Antimicrob Agents Chemother. 2006;50(10):3297–3304. doi:10.1128/AAC00251-06.• The mechanism by which TDF is extruded from the tubular cells to the luminal compartment of the proximal tubule is explained. MRP-4 on the apical side of the proximal tubule is explained as the key transporter that effluxes TDF into the lumen. The authors also highlight that an inhibitor of MRP-4 can result in accumulation of TDF.
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(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.10
, pp. 3297-3304
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Ray, A.S.1
Cihlar, T.2
Robinson, K.L.3
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10
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77949875327
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Tenofovir-associated bone density loss
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I.F.Grigby. Tenofovir-associated bone density loss. Ther Clin Risk Manag. 2010;6:41–47.
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(2010)
Ther Clin Risk Manag
, vol.6
, pp. 41-47
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Grigby, I.F.1
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11
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84910629450
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The role of drug transporters in the kidney: lessons from tenofovir
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D.M.Moss, M.Neary, A.Owen. The role of drug transporters in the kidney: lessons from tenofovir. Front Pharmacol. 2014;5:248.
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(2014)
Front Pharmacol
, vol.5
, pp. 248
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Moss, D.M.1
Neary, M.2
Owen, A.3
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12
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33750570685
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Pharmacokinetics and safety of tenofovir disoproxil fumarate on coadministration with lopinavir/ritonavir
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B.P.Kearney, A.Mathias, A.Mittan, et al. Pharmacokinetics and safety of tenofovir disoproxil fumarate on coadministration with lopinavir/ritonavir. J Acquir Immune Defic Syndr. 2006;3(43):278–283.• This paper presents information on the factors associated with TDF-associated renal impairment.
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(2006)
J Acquir Immune Defic Syndr
, vol.3
, Issue.43
, pp. 278-283
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Kearney, B.P.1
Mathias, A.2
Mittan, A.3
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13
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38349171607
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The effect of lopinavir/ritonavir on the renal clearance of tenofovir
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Feb
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J.J.Kiser, M.L.Carten, C.L.Aquilante, et al. The effect of lopinavir/ritonavir on the renal clearance of tenofovir. Clin Pharmacol Ther. 2008 Feb;2(83):265–272.•• This paper provides pharmacokinetics evidence of increased area under the curve of TDF when co-administered with ritonavir-boosted LPV. However, the writers say that the TDF’s increased AUC did not have any clinical significance.
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(2008)
Clin Pharmacol Ther
, vol.2
, Issue.83
, pp. 265-272
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Kiser, J.J.1
Carten, M.L.2
Aquilante, C.L.3
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14
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84898759641
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Antiretroviral and the kidneys in current clinical practice
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J.C.Yombi, A.Pozniak, M.Boffito, et al. Antiretroviral and the kidneys in current clinical practice. AIDS. 2014;5(28):621–632.•• The writers of this paper explain the slower rate of excretion of TDF when co-administered with LPV/r, but they questioned the clinical significance of the slowed excretion.
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(2014)
AIDS
, vol.5
, Issue.28
, pp. 621-632
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Yombi, J.C.1
Pozniak, A.2
Boffito, M.3
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15
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66749120096
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Chronic kidney disease prevalence and risk factors among HIV-infected patients
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L.Sorli Maria, G.Ana, M.Milagro, et al. Chronic kidney disease prevalence and risk factors among HIV-infected patients. J Acquir Immune Defic Syndr. 2008;48(4):506–508.
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(2008)
J Acquir Immune Defic Syndr
, vol.48
, Issue.4
, pp. 506-508
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Sorli Maria, L.1
Ana, G.2
Milagro, M.3
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16
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0141468244
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Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention Circulation
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M.J.Sarnak, A.S.Levey, A.C.Shoolwerth, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention Circulation. J Am Heart Assoc. 2003; 108:2154–2169.
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(2003)
J Am Heart Assoc
, vol.108
, pp. 2154-2169
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Sarnak, M.J.1
Levey, A.S.2
Shoolwerth, A.C.3
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17
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84875968406
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Nephrotoxicity of antiretroviral agents: is the list getting longer?
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D.M.Fine, J.E.Gallant. Nephrotoxicity of antiretroviral agents: is the list getting longer? J Infect Dis. 2013;207:1349–1351.
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(2013)
J Infect Dis
, vol.207
, pp. 1349-1351
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Fine, D.M.1
Gallant, J.E.2
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19
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84952990188
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Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study
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A.Mocroft, J.D.Lundgren, M.Ross, et al. Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study. Lancet HIV. 2015;3(1):e23–e32.• The authors highlight the fact that long-term use of antiretroviral therapy increases adverse drug reactions with the kidneys at risk of being damaged by the large amount of drugs that reach them. The authors also highlight that the physiological processes of water reabsorption leave a high concentration of toxins in the tubules, which is an environment toxic to the epithelial cells.
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(2015)
Lancet HIV
, vol.3
, Issue.1
, pp. e23-e32
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Mocroft, A.1
Lundgren, J.D.2
Ross, M.3
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20
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77953724330
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The aging kidney: physiological changes
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J.R.Weinstein, S.Anderson. The aging kidney: physiological changes. Adv Chronic Kidney Dis. 2010;17(4):302–307. doi:10.1053/j.ackd.2010.05.002.
-
(2010)
Adv Chronic Kidney Dis
, vol.17
, Issue.4
, pp. 302-307
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Weinstein, J.R.1
Anderson, S.2
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21
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84899786511
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Effect of baseline renal function on tenofovir-containing antiretroviral therapy outcomes in Zambia
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L.Mulenga, P.Musonda, A.Mwango, et al. Effect of baseline renal function on tenofovir-containing antiretroviral therapy outcomes in Zambia. Clin Infect Dis. 2014;58:1473–1480.
-
(2014)
Clin Infect Dis
, vol.58
, pp. 1473-1480
-
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Mulenga, L.1
Musonda, P.2
Mwango, A.3
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23
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70349780794
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Renal function with use of a tenofovir-containing initial antiretroviral regimen
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J.E.Gallant, R.D.Moore. Renal function with use of a tenofovir-containing initial antiretroviral regimen. Aids. 2009;Sep 24;23(15):1971–1975. doi:10.1097/QAD.0b013e32832c96e9.
-
(2009)
Aids
, vol.Sep 24;23
, Issue.15
, pp. 1971-1975
-
-
Gallant, J.E.1
Moore, R.D.2
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24
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-
39349112711
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Greater tenofovir-associated renal function decline with protease inhibitor-based versus nonnucleoside reverse-transcriptase inhibitor-based therapy
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M.Goicoechea, S.Liu, B.Best, et al. Greater tenofovir-associated renal function decline with protease inhibitor-based versus nonnucleoside reverse-transcriptase inhibitor-based therapy. J Infect Dis. 2008;197(1):102–108.
-
(2008)
J Infect Dis
, vol.197
, Issue.1
, pp. 102-108
-
-
Goicoechea, M.1
Liu, S.2
Best, B.3
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25
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84944582987
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Foster City (CA):
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Gilead Sciences Incorporated. Tenofovir disoproxil fumarate prescribing information. Foster City (CA): Gilead Sciences, Inc.; 2013. Available from: http://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/viread/viread_pi.pdf
-
(2013)
Tenofovir disoproxil fumarate prescribing information
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