Eulogy for the clinical research center

Journal of Clinical Investigation

Volumn 126, Issue 7, 2016, Pages 2388-2391

  Nathan, David G ^a   Nathan, David M ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL LABORATORY; CLINICAL RESEARCH; CLINICAL RESEARCH CENTER; FUNDING; HEALTH CARE FACILITY; HISTORY OF MEDICINE; HUMAN; MEDICINE; METHODOLOGY; NATIONAL HEALTH ORGANIZATION; PRIORITY JOURNAL; ECONOMICS; FINANCIAL MANAGEMENT; HOSPITAL MANAGEMENT; MEDICAL RESEARCH; ORGANIZATION AND MANAGEMENT; PERSONNEL; TRANSLATIONAL RESEARCH; UNITED STATES;

BIOMEDICAL RESEARCH; HOSPITAL ADMINISTRATION; HUMANS; NATIONAL INSTITUTES OF HEALTH (U.S.); RESEARCH PERSONNEL; RESEARCH SUPPORT AS TOPIC; TRANSLATIONAL MEDICAL RESEARCH; UNITED STATES;

EID: 84978438346     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI88381     Document Type: Article

References (20)

1. National Center for Advancing Translational Sciences; NIH. Department of Health and Human Services, Clinical and Translational Science Award (U54). https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-14-009.html. Published September 12, 2014. Accessed May 13, 2016.
2. CTSA Principal Investigators, et al. Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS). Clin Transl Sci. 2012; 5 (2): 121-129.
3. Robertson D, Williams GH, eds. Clinical and Translational Science Infrastructure in Clinical and Translational Research: Principles of Human Research. 1st ed. London, United Kingdom: Academic Press; 2009.
4. Committee to Review the Clinical Translational Science Awards Program at the National Center for Advancing Translational Sciences; Board on Health Sciences Policy; Institute of Medicine, authors. Leshner AI, Terry SF, Schultz AM, Liverman CT, eds. The CTSA Program At NIH. Opportunities For Advancing Clinical And Translational Research. Washington, DC, USA: The National Academies Press; 2013.
5. Working Group of the NCATS Advisory Council to the Director. NCATS Advisory Council Working Group on the IOM Report: The CTSA Program at NIH. https://ncats.nih.gov/files/CTSA-IOM-WG-draft-report.pdf. Published May 16, 2014. Accessed May 13, 2016.
6. Means JH Ward 4-the Mallinckrodt Research Ward of the Massachusetts General Hospital. Cambridge, Massachusetts, USA: Harvard University Press; 1958.
7. Elrod JM, Karnad AB. Boston City Hospital and the Thorndike Memorial Laboratory: the birth of modern haematology. Br J Haematol. 2003; 121 (3): 383-389.
8. Dole VP, Nyswander M. A medical treatment for diacetylmorphine (heroin) addiction. A clinical trial with methadone hydrochloride. JAMA. 1965; 193: 646-650.
9. Markowitz M, et al. The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses. J Infect Dis. 1999; 179 (3): 527-537.
10. Comite F, Cutler GB, Rivier J, Vale WW, Loriaux DL, Crowley WF. Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. A preliminary report. N Engl J Med. 1981; 305 (26): 1546-1550.
11. Mansfield MJ, et al. Long-term treatment of central precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. Effects on somatic growth and skeletal maturation. N Engl J Med. 1983; 309 (21): 1286-1290.
12. Klibanski A, Neer RM, Beitins IZ, Ridgway EC, Zervas NT, McArthur JW. Decreased bone density in hyperprolactinemic women. N Engl J Med. 1980; 303 (26): 1511-1514.
13. Klibanski A, Greenspan SL. Increase in bone mass after treatment of hyperprolactinemic amenorrhea. N Engl J Med. 1986; 315 (9): 542-546.
14. [No authors listed]. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med. 1993; 329 (14): 977-986.
15. Purnell JQ, Zinman B, Brunzell JD, DCCT/EDIC Research Group. The effect of excess weight gain with intensive diabetes mellitus treatment on cardiovascular disease risk factors and atherosclerosis in type 1 diabetes mellitus: results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC) study. Circulation. 2013; 127 (2): 180-187.
16. Knowler WC, et al. Reduction in incidence of Type 2 diabetes with life-style intervention or metformin. N Engl J Med. 2002; 346 (6):393-403.
17. Executive Summary-NIH Director's Panel on Clinical Research Report 12/97. http://grants.nih.gov/grants/NIH-Directors-Panel-Clinical-Research-Report-199712.pdf. Accessed May 13, 2016.
18. Zerhouni EA Translational and clinical science-time for a new vision. N Engl J Med. 2005; 353 (15):1621-1623.
19. NIH. Physician-Scientist Workforce Working Group Report. http://acd.od.nih.gov/reports/psw-report-acd-06042014.pdf. Published June 1, 2014. Accessed May 13, 2016.
20. Freire M, et al. ACD Working Group Activities: National Center for Advancing Translational Sciences. Summary of Findings. http://acd.od.nih.gov/reports/ACD-NCATSWGR-09212011.pdf. Published September 21, 2011. Accessed May 13, 2016.