Improved excipient functionality by coprocessing

Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems

Volumn , Issue , 2006, Pages 109-126

  Gupta, Piyush ^a   Nachaegari, Satish K ^a   Bansal, Arvind K ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84978401737     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (58)

1. Banker GS, Anderson NR. Tablets. In: Lachman L, Lieberman HA, Kanig JL, eds. The Theory and Practice of Industrial Pharmacy. Bombay: Varghese Publishing House, 1986: 293-345.
2. USP Subcommittee. Excipients. Pharm Forum 1992; 18: 4387.
3. Moreton RC. Excipient functionality. Pharm Technol 2004: 98, 99, 119.
4. Ermens H. Pharmaceutical excipients-the past and future. Business Briefing: Pharmagenerics 2004: 1-3.
5. York P. Crystal engineering and particle design for the powder compaction process. Drug Dev Ind Pharm 1992; 18: 677-721.
6. Pifferi G, Santoro P, Pedrani M. Quality and functionality of excipients. Il Farmaco 1999; 54: 1-14.
7. Bansal AK, Nachaegari SK. High-functionality excipients for solid dosage forms. Business Briefing: Pharmagenerics 2002: 38-44.
8. Bansal AK. Improved excipients by solid-state manipulation. The Industrial Pharmacist 2003: 9-12.
9. Nachaegari SK, Bansal AK. Coprocessed excipients for solid dosage forms. Pharm Technol 2004; 28: 52-64.
10. Czeisler JL, Perlman KP. Diluents. In: Swarbrick J, Boylan JC, eds. Encyclopedia of Pharmaceutical Technology. New York: Marcel Dekker, Inc., 1998: 37-83.
11. Shangraw RF, Demarest DA. A survey of current industrial practices in the formulation and manufacture of tablets and capsules. Pharm Technol 1993; 17: 32-44.
12. Gohel MC, Jogani PD. An investigation of the direct-compression characteristics of coprocessed lactose-microcrystalline cellulose using statistical design. Pharm Technol 1999: 54-62.
13. IPEC-Americas, “Why IPEC-Americas is needed.” http://www.ipecamericas.org/public/whyneeded.html (accessed on 16 January 2003).
14. Blecher L. Pharmaceutical excipients-producers and users strengthen their voice. Pharm Technol 1993; 17: 38-39.
15. Restocking the excipient superstore. Pharmaceutical Formulation and Quality. International Pharmaceutical Excipients Council (IPEC), 2000 (February/March).
16. Shangraw RF. Compressed tablets by direct compression. In: Leiberman HA, Lachman L, Schwatz JB, eds. Pharmaceutical Dosage Forms: Tablets. New York: Marcel Dekker, Inc., 1990: 195-246.
17. Armstrong NA, Palfrey LP. The effect of machine speed on the consolidation of four directly compressible tablet diluents. J Pharm Pharmacol 1989; 41: 149-151.
18. Steinberg M, Blecher L, Mercill A. From inactive ingredients to pharmaceutical excipients. Pharm Technol 2001; 25: 62-64.
19. Tobyn MJ, McCarthy GP, Staniforth JN, Edge S. Physicochemical comparison between microcrystalline cellulose and silicified microcrystalline cellulose. Int J Pharm 1998; 169: 183-194.
20. Moreton RC. Tablet excipients to the year 2001: a look into the crystal ball. Drug Dev Ind Pharm 1996; 22: 11-23.
21. Robertson MI. Regulatory issues with excipients. Int J Pharm 1999; 187: 273-276.
22. CyDex, “Innovative drug delivery technologies.” www.captisol.com (accessed on 16 January 2003).
23. CyDex, “Captisol.” www.cydexinc.com/CaptisolProductApprovals.pdf (accessed on 16 January 2003).
24. Shangraw RF, Wallace JW, Bowers FM. Morphology and functionality in tablet excipients for direct compression: Part I. Pharm Technol 1981; 5: 69-78.
25. Shangraw RF. Emerging trends in the use of pharmaceutical excipients. Pharm Technol 1997; 21: 36-42.
26. York P. Molecules, materials science and medicines. Pharm J 2001; 267: 437-440.
27. Jones TM. The influence of physical characteristics of excipients on the design and preparation of tablets and capsules. Pharm Ind 1977; 39: 469-476.
28. Byrn S, Pfeiffer R, Ganey M, Hoiberg C, Poochikian G. Pharmaceutical solids: a strategic approach to regulatory considerations. Pharm Res 1995; 12: 945-954.
29. Brittain HG. Particle-size distribution, Part I. Representations of particle shape, size, and distribution. Pharm Technol 2001: 38-45.
30. Standly-Wood N. WS-16, Powder and Bulk Solids. Conference and Exhibition, Chicago, 1989.
31. Reimerdes D, Aufmuth KP. Tableting with co-processed lactose-cellulose excipient. Manuf Chemist 1992; 63: 21-24.
32. Reimerdes D. The near future of tablet excipients. Manuf Chemist 1993; 64: 14-15.
33. Modliszewski JJ, Ballard AD. Coprocessed galactomannan-glucomannan. US Patent No.5,498,436, 1996.
34. Mehra DK, West KP, Wiggins JD. Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation. US Patent No. 4,744,987, 1988.
35. Bolhius GK, Chowhan ZT. Materials for direct compaction. In: Alderborn G, Nystrom C, eds. Pharmaceutical Powder Compaction Technology. New York: Marcel Dekker, Inc., 1996: 419-500.
36. Marshall K. Compression and consolidation of powdered solids. In: Lachman L, Lieberman HA, Kanig JL, eds. The Theory and Practice of Industrial Pharmacy. Bombay: Varghese Publishing House, 1986: 66-99.
37. Maarschalk KvdV, Bolhuis GK. Improving properties of materials for direct compaction. Pharm Technol 1999; 23: 34-46, 96.
38. Casahoursat L, Lemagen G, Larrouture D. The use of stress relaxation trials to characterize tablet capping. Drug Dev Ind Pharm 1988; 14: 2179-2199.
39. Howard SA, Lai J-W. Flow properties of solids. In: Swarbrick J, Boylan JC, eds. Encyclopedia of Pharmaceutical Technology. New York: Marcel Dekker, Inc., 1998: 141-169.
40. Heywood H. The evaluation of powders. J Pharm Pharmacol 1963; 15: 56T-74T.
41. Ridgway K, Rupp R. The effect of particle shape on powder properties. J Pharm Pharmacol 1969; 21(suppl): 30S-39S.
42. Allen JD. Improving DC with SMCC. Manuf Chemist 1996; 67: 19-23.
43. Nada AH, Graf E. Evaluation of Vitacel M80K as a new direct compressible vehicle. Eur J Pharm Biopharm 1998; 46: 347-353.
44. Sherwood BE, Becker JW. A new class of high functionality excipients: silicified microcrystalline cellulose. Pharm Technol 1998; 22: 78-88.
45. Belda PM, Mielck JB. The tableting behavior of Cellactose compared with mixtures of celluloses with lactoses. Eur J Pharm Biopharm 1996; 42: 325-330.
46. Schmidt PC, Rubensdorfer CJW. Evaluation of Ludipress as a “multipurpose excipient” for direct compression. Part I: powder characteristics and tableting properties. Drug Dev Ind Pharm 1994; 20: 2899-2925.
47. Joshi V. Excipient choice in solid dosage forms. Drug Deliv Technol 2002; 2(6): 36-40.
48. Wagner KG, Dressler JA. A corn starch/alpha-lactose monohydrate compound as a directly compressible excipient. Pharm Technol (Europe) March 2003.
49. Staniforth JN, Chatrath M. Towards a new class of high functionality tablet binders. I: Quasi-hornification of microcrystalline cellulose and loss of functionality. Pharm Res 1996; 13: S208.
50. Flores LE, Arellano RL, Esquivel JJD. Study of load capacity of Avicel PH-200 and Cellactose, two direct compression excipients, using experimental design. Drug Dev Ind Pharm 2000; 26: 465-469.
51. Meggelaars MM, Biggelaar HAvd, Kussendrager KD. Tableting excipient. US Patent No. 5,534,555, 1996.
52. Menon A, Gillece T, Chakrabarti S. Co-processing method for making a free flowing compressible powder and tablet therefrom. US Patent No. 5,560,927, 1996.
53. Gohel MC, Jogani PD. Functionality testing of a multifunctional directly compressible adjuvant containing lactose, polyvinylpyrrolidone, and croscarmellose sodium. Pharm Technol 2002: 64-82.
54. Limwong V, Sutanthavibul N, Kulvanich P. Spherical composite particles of rice starch and microcrystalline cellulose: a new coprocessed excipient for direct compression. AAPS Pharm Sci Tech 2004; 5 (article 30).
55. Joshi AA, Duriez X. Added functionality excipients: an answer to challenging formulations. Pharm Technol (Excipients and Solid Dosage Forms) 2004: 12-19.
56. Prosolv. Technical report: tableting binder improves production. New York: Penwest Pharmaceuticals, 2001.
57. DeMerlis CC, Goldring JM. Marketing new excipients: clearing regulatory hurdles. Pharm Technol 2003: 102-108.
58. Moreton RC. Cellulose, silicified microcrystalline. In: Kibbe AH ed. Handbook of Pharmaceutical Excipients. Washington, D.C.: American Pharmaceutical Association and London: Pharmaceutical Press, 2000: 110-111.