메뉴 건너뛰기




Volumn 203, Issue , 2016, Pages 291-296

The prognostic role of metformin in patients with endometrial cancer: a retrospective study

Author keywords

Diabetes; Endometrial cancer; Metformin; Obesity; Prognosis

Indexed keywords

METFORMIN; ANTIDIABETIC AGENT;

EID: 84978272054     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2016.06.013     Document Type: Article
Times cited : (26)

References (22)
  • 1
    • 70749106139 scopus 로고    scopus 로고
    • Metformin is a potent inhibitor of endometrial cancer cell proliferation – implications for a novel treatment strategy
    • [1] Cantrell, L.A., Zhou, C., Mendivil, A., Malloy, K.M., Gehring, P.A., Bae-Jump, V.L., Metformin is a potent inhibitor of endometrial cancer cell proliferation – implications for a novel treatment strategy. Gynecol Oncol 116 (2010), 92–98.
    • (2010) Gynecol Oncol , vol.116 , pp. 92-98
    • Cantrell, L.A.1    Zhou, C.2    Mendivil, A.3    Malloy, K.M.4    Gehring, P.A.5    Bae-Jump, V.L.6
  • 2
    • 84964694192 scopus 로고    scopus 로고
    • Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer
    • [2] Schuler, K.M., Rambally, B.S., DiFurio, M.J., et al. Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancer. Cancer Med 4:2 (2015), 161–173.
    • (2015) Cancer Med , vol.4 , Issue.2 , pp. 161-173
    • Schuler, K.M.1    Rambally, B.S.2    DiFurio, M.J.3
  • 3
    • 84858695046 scopus 로고    scopus 로고
    • Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis
    • [3] Noto, H., Goto, A., Tsujimoto, T., Noda, M., Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis. PLoS ONE, 7(3), 2012, e33411, 10.1371/journal.pone.0033411.
    • (2012) PLoS ONE , vol.7 , Issue.3 , pp. e33411
    • Noto, H.1    Goto, A.2    Tsujimoto, T.3    Noda, M.4
  • 4
    • 84942112910 scopus 로고    scopus 로고
    • Metformin and breast and gynecological cancer risk among women with diabetes
    • [4] Soffer, D., Shi, J., Chung, J., et al. Metformin and breast and gynecological cancer risk among women with diabetes. BMJ Open Diabetes Res Care, 3(1), 2015, e000049, 10.1136/bmjdrc-2014-000049.eCollection 2015.
    • (2015) BMJ Open Diabetes Res Care , vol.3 , Issue.1 , pp. e000049
    • Soffer, D.1    Shi, J.2    Chung, J.3
  • 5
    • 84892961071 scopus 로고    scopus 로고
    • GLOBOCAN 2012 v1.0, Cancer incidence and mortality worldwide: IARC CancerBase No.11 [Internet]
    • International Agency for Research on Cancer Lyon, France Available from: [accessed 21.03.15]
    • [5] Ferlay, J., Soerjomataram, I., Ervik, M., et al. GLOBOCAN 2012 v1.0, Cancer incidence and mortality worldwide: IARC CancerBase No.11 [Internet]. 2013, International Agency for Research on Cancer, Lyon, France Available from: http://globocan.iarc.fr [accessed 21.03.15].
    • (2013)
    • Ferlay, J.1    Soerjomataram, I.2    Ervik, M.3
  • 6
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
    • [6] Renehan, A.G., Tyson, M., Egger, M., Heller, R.F., Zwahlen, M., Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 371:9612 (2008), 569–578.
    • (2008) Lancet , vol.371 , Issue.9612 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3    Heller, R.F.4    Zwahlen, M.5
  • 7
    • 84921024951 scopus 로고    scopus 로고
    • Metabolic syndrome and risk of endometrial cancer in the United States: a study in the SEER-Medicare linked database
    • [7] Trabert, B., Wentzensen, N., Felix, A.S., Yang, H.P., Sherman, M.E., Brinton, L.A., Metabolic syndrome and risk of endometrial cancer in the United States: a study in the SEER-Medicare linked database. Cancer Epidemiol Biomarkers Prev 24:1 (2015), 251–257.
    • (2015) Cancer Epidemiol Biomarkers Prev , vol.24 , Issue.1 , pp. 251-257
    • Trabert, B.1    Wentzensen, N.2    Felix, A.S.3    Yang, H.P.4    Sherman, M.E.5    Brinton, L.A.6
  • 8
    • 84908498848 scopus 로고    scopus 로고
    • Effects of metformin on endometrial cancer cell growth in vivo: a preoperative prospective trial
    • [8] Mitsuhashi, A., Kiyokawa, T., Sato, Y., Shozu, M., Effects of metformin on endometrial cancer cell growth in vivo: a preoperative prospective trial. Cancer 120 (2014), 2986–2995.
    • (2014) Cancer , vol.120 , pp. 2986-2995
    • Mitsuhashi, A.1    Kiyokawa, T.2    Sato, Y.3    Shozu, M.4
  • 9
    • 84921757756 scopus 로고    scopus 로고
    • Antiproliferative effect of metformin on the endometrium – a clinical trial
    • [9] Tabrizi, A.D., Melli, M.S., Forough, M., Ghojazadeh, M., Bidadi, S., Antiproliferative effect of metformin on the endometrium – a clinical trial. Asian Pac J Cancer Prev 15:23 (2014), 10067–10070.
    • (2014) Asian Pac J Cancer Prev , vol.15 , Issue.23 , pp. 10067-10070
    • Tabrizi, A.D.1    Melli, M.S.2    Forough, M.3    Ghojazadeh, M.4    Bidadi, S.5
  • 10
    • 84894041491 scopus 로고    scopus 로고
    • Metformin is associated with improved survival in endometrial cancer
    • [10] Ko, E.M., Walter, P., Jackson, A., et al. Metformin is associated with improved survival in endometrial cancer. Gynecol Oncol 132:2 (2014), 438–442.
    • (2014) Gynecol Oncol , vol.132 , Issue.2 , pp. 438-442
    • Ko, E.M.1    Walter, P.2    Jackson, A.3
  • 11
    • 84892735827 scopus 로고    scopus 로고
    • Metformin use and endometrial cancer survival
    • [11] Newadunsky, N.S., Van Arsdale, A., Strickler, H.D., et al. Metformin use and endometrial cancer survival. Gynecol Oncol 132:1 (2014), 236–240.
    • (2014) Gynecol Oncol , vol.132 , Issue.1 , pp. 236-240
    • Newadunsky, N.S.1    Van Arsdale, A.2    Strickler, H.D.3
  • 12
    • 84949033605 scopus 로고    scopus 로고
    • The effect of diabetes and metformin on clinical outcomes is negligible in risk-adjusted endometrial cancer cohorts
    • [12] Al Hilli, M.M., Bakkum-Gamez, J.M., Mariani, A., et al. The effect of diabetes and metformin on clinical outcomes is negligible in risk-adjusted endometrial cancer cohorts. Gynecol Oncol 140 (2016), 270–276.
    • (2016) Gynecol Oncol , vol.140 , pp. 270-276
    • Al Hilli, M.M.1    Bakkum-Gamez, J.M.2    Mariani, A.3
  • 13
    • 84958213162 scopus 로고    scopus 로고
    • Association of metformin use with outcomes in advanced endometrial cancer treated with chemotherapy
    • [13] Ezewuiro, O., Grushko, T.A., Kocherginsky, M., et al. Association of metformin use with outcomes in advanced endometrial cancer treated with chemotherapy. PLOS one, 11(1), 2016, e0147145, 10.1371/journal.pone.0147145.
    • (2016) PLOS one , vol.11 , Issue.1 , pp. e0147145
    • Ezewuiro, O.1    Grushko, T.A.2    Kocherginsky, M.3
  • 14
    • 84957603034 scopus 로고    scopus 로고
    • Use of metformin in obese women with type I endometrial cancer is associated with reduced incidence of cancer recurrence
    • [14] Hall, C., Stone, R.L., Gehlot, A., Zorn, K.K., Burnett, A.F., Use of metformin in obese women with type I endometrial cancer is associated with reduced incidence of cancer recurrence. Int J Gynecol Cancer 26 (2016), 313–317.
    • (2016) Int J Gynecol Cancer , vol.26 , pp. 313-317
    • Hall, C.1    Stone, R.L.2    Gehlot, A.3    Zorn, K.K.4    Burnett, A.F.5
  • 15
    • 33845229580 scopus 로고    scopus 로고
    • Carcinoma of the corpus uteri. FIGO 6th annual report on the results of treatment in gynecologic cancer
    • [15] Creasman, W.T., Odicino, F., Maisonneuve, P., et al. Carcinoma of the corpus uteri. FIGO 6th annual report on the results of treatment in gynecologic cancer. Int J Gynaecol Obstet 95:Suppl. 1 (2006), 105–143.
    • (2006) Int J Gynaecol Obstet , vol.95 , pp. 105-143
    • Creasman, W.T.1    Odicino, F.2    Maisonneuve, P.3
  • 16
    • 84931572183 scopus 로고    scopus 로고
    • Corpus Uteri. AJCC Cancer Staging Manual
    • 7th ed. Springer New York
    • [16] American Joint Committee on Cancer, Corpus Uteri. AJCC Cancer Staging Manual. 7th ed., 2010, Springer, New York, 403.
    • (2010) , pp. 403
    • American Joint Committee on Cancer1
  • 17
    • 77949541793 scopus 로고    scopus 로고
    • The prognostic value of plasma fibrinogen levels in patients with endometrial cancer: a multi-centre trial
    • [17] Seebacher, V., Polterauer, S., Grimm, C., et al. The prognostic value of plasma fibrinogen levels in patients with endometrial cancer: a multi-centre trial. Br J Cancer 16 (2010), 952–956.
    • (2010) Br J Cancer , vol.16 , pp. 952-956
    • Seebacher, V.1    Polterauer, S.2    Grimm, C.3
  • 18
    • 0034616634 scopus 로고    scopus 로고
    • Altered PTEN expression as a diagnostic marker for the earlies endometrial precancers
    • [18] Mutter, G.L., Lin, M.C., Fitzgerald, J.T., et al. Altered PTEN expression as a diagnostic marker for the earlies endometrial precancers. J Natl Cancer Inst 92 (2000), 924–930.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 924-930
    • Mutter, G.L.1    Lin, M.C.2    Fitzgerald, J.T.3
  • 19
    • 84890538979 scopus 로고    scopus 로고
    • Another surprise from metformin: novel mechanism of action via K-Ras influences endometrial cancer response to therapy
    • [19] Iglesias, D.A., Yates, M.S., van der Hoeven, D., et al. Another surprise from metformin: novel mechanism of action via K-Ras influences endometrial cancer response to therapy. Mol Cancer Ther 12:12 (2013), 2847–2856.
    • (2013) Mol Cancer Ther , vol.12 , Issue.12 , pp. 2847-2856
    • Iglesias, D.A.1    Yates, M.S.2    van der Hoeven, D.3
  • 20
    • 0348012945 scopus 로고    scopus 로고
    • Prediagnostic levels of C-peptide, IGF-1, IGFBP-1, -2 and -3 and risk of endometrial cancer
    • [20] Lukanova, A., Zeleniuch-Jacquotte, A., Lundin, E., et al. Prediagnostic levels of C-peptide, IGF-1, IGFBP-1, -2 and -3 and risk of endometrial cancer. Int J Cancer 108:2 (2004), 262–268.
    • (2004) Int J Cancer , vol.108 , Issue.2 , pp. 262-268
    • Lukanova, A.1    Zeleniuch-Jacquotte, A.2    Lundin, E.3
  • 21
    • 33745108419 scopus 로고    scopus 로고
    • Leptin prmotes the proliferative response and invasivenenss in human endometrial cancer cells by activating multiple signal-transduction pathways
    • [21] Sharma, D., Saxena, N.K., Vertino, P.M., Anania, F.A., Leptin prmotes the proliferative response and invasivenenss in human endometrial cancer cells by activating multiple signal-transduction pathways. Endocr Relat Cancer 13 (2006), 629–640.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 629-640
    • Sharma, D.1    Saxena, N.K.2    Vertino, P.M.3    Anania, F.A.4
  • 22
    • 84892782859 scopus 로고    scopus 로고
    • Prevalence of obesity among men and women, 2012 (or nearest year), in Health at a Glance: Europe 2014
    • OECD Publishing Paris
    • [22] OECD, Prevalence of obesity among men and women, 2012 (or nearest year), in Health at a Glance: Europe 2014. 2014, OECD Publishing, Paris, 10.1787/health_glance_eur-2014-graph51-en.
    • (2014)
    • OECD1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.