Mutations in glucocerebrosidase are a major genetic risk factor for Parkinson's disease and increase susceptibility to dementia in a Flanders-Belgian cohort

Neuroscience Letters

Volumn 629, Issue , 2016, Pages 160-164

  Crosiers, David ^a,b,c   Verstraeten, Aline ^a,b   Wauters, Eline ^a,b   Engelborghs, Sebastiaan ^a,b,d   Peeters, Karin ^a,b   Mattheijssens, Maria ^a,b   De Deyn, Peter P ^a,b,d   Theuns, Jessie ^a,b   Van Broeckhoven, Christine ^a,b   Cras, Patrick ^a,b,c  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^d Hospital Network Antwerp   (Belgium)

Author keywords

GBA; Genotype phenotype correlation; Glucocerebrosidase; Parkinson's disease

Indexed keywords

ADULT; AGED; ARTICLE; BELGIAN; CONTROLLED STUDY; DEMENTIA; EXON; FEMALE; GENE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE PHENOTYPE CORRELATION; GLUCOSYLCERAMIDASE GENE; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PRIORITY JOURNAL; RATING SCALE; RISK FACTOR; SCORING SYSTEM; SEQUENCE ANALYSIS; BELGIUM; COHORT ANALYSIS; COMPLICATION; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; HETEROZYGOTE; MIDDLE AGED; MUTATION; PHENOTYPE; SEVERITY OF ILLNESS INDEX;

GLUCOSYLCERAMIDASE;

AGED; BELGIUM; COHORT STUDIES; DEMENTIA; EXONS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GLUCOSYLCERAMIDASE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTATION; PARKINSON DISEASE; PHENOTYPE; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 84978252668     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2016.07.008     Document Type: Article

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