Establishing sickle cell diagnostics and characterizing a paediatric sickle cell disease cohort in Malawi

British Journal of Haematology

Volumn 174, Issue 2, 2016, Pages 325-329

  Heimlich, J Brett ^a,b   Chipoka, Godwin ^a   Kamthunzi, Portia ^a   Krysiak, Robert ^a   Majawa, Yacinta ^a   Mafunga, Pilirani ^a   Fedoriw, Yuri ^c   Phiri, Ajib ^a   Key, Nigel S ^c   Ataga, Kenneth I ^c   Gopal, Satish ^a,c  

^a UNIVERSITY OF MALAWI   (Malawi)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Paediatrics; Red cell disorders; Sickle; Sickle cell disease

Indexed keywords

HEMOGLOBIN AA; HEMOGLOBIN AS; HEMOGLOBIN VARIANT; PYRIMETHAMINE PLUS SULFADOXINE; UNCLASSIFIED DRUG;

ADOLESCENT; BLOOD CELL COUNT; CHILD; COHORT ANALYSIS; ELECTROPHORESIS; FEMALE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALARIA; MALARIA CONTROL; MALAWI; MALE; PRIORITY JOURNAL; SICKLE CELL ANEMIA;

EID: 84978129575     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13769     Document Type: Letter

References (10)

1. Adams, R.J., McKie, V.C., Hsu, L., Files, B., Vichinsky, E., Pegelow, C., Abboud, M., Gallagher, D., Kutlar, A., Nichols, F.T., Bonds, D.R. & Brambilla, D. (1998) Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. The New England journal of medicine, 339, 5–11.
2. Brabin, B.J., Prinsen-Geerligs, P.D., Verhoeff, F.H., Fletcher, K.A., Chimsuku, L.H., Ngwira, B.M., Leich, O.J. & Broadhead, R.L. (2004) Haematological profiles of the people of rural southern Malawi: an overview. Annals of tropical medicine and parasitology, 98, 71–83.
3. Grosse, S.D., Odame, I., Atrash, H.K., Amendah, D.D., Piel, F.B. & Williams, T.N. (2011) Sickle cell disease in Africa: a neglected cause of early childhood mortality. American journal of preventive medicine, 41, S398–405.
4. Gurkan, S., Scarponi, K.J., Hotchkiss, H., Savage, B. & Drachtman, R. (2010) Lactate dehydrogenase as a predictor of kidney involvement in patients with sickle cell anemia. Pediatric nephrology, 25, 2123–2127.
5. Makani, J., Kirkham, F.J., Komba, A., Ajala-Agbo, T., Otieno, G., Fegan, G., Williams, T.N., Marsh, K. & Newton, C.R. (2009) Risk factors for high cerebral blood flow velocity and death in Kenyan children with Sickle Cell Anaemia: role of haemoglobin oxygen saturation and febrile illness. British journal of haematology, 145, 529–532.
6. McAuley, C.F., Webb, C., Makani, J., Macharia, A., Uyoga, S., Opi, D.H., Ndila, C., Ngatia, A., Scott, J.A., Marsh, K. & Williams, T.N. (2010) High mortality from Plasmodium falciparum malaria in children living with sickle cell anemia on the coast of Kenya. Blood, 116, 1663–1668.
7. Njamnshi, A.K., Mbong, E.N., Wonkam, A., Ongolo-Zogo, P., Djientcheu, V.D., Sunjoh, F.L., Wiysonge, C.S., Sztajzel, R., Mbanya, D., Blackett, K.N., Dongmo, L. & Muna, W.F. (2006) The epidemiology of stroke in sickle cell patients in Yaounde, Cameroon. J Neurol Sci, 250, 79–84.
8. Piel, F.B., Patil, A.P., Howes, R.E., Nyangiri, O.A., Gething, P.W., Dewi, M., Temperley, W.H., Williams, T.N., Weatherall, D.J. & Hay, S.I. (2013) Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates. Lancet, 381, 142–151.
9. Ranque, B., Menet, A., Diop, I.B., Thiam, M.M., Diallo, D., Diop, S., Diagne, I., Sanogo, I., Kingue, S., Chelo, D., Wamba, G., Diarra, M., Anzouan, J.B., N'Guetta, R., Diakite, C.O., Traore, Y., Legueun, G., Deme-Ly, I., Belinga, S., Boidy, K., Kamara, I., Tharaux, P.-L. & Jouven, X. (2014) Early renal damage in patients with sickle cell disease in sub-Saharan Africa: a multinational, prospective, cross-sectional study. The Lancet Haematology, 1, e64–e73.
10. Saraf, S.L., Zhang, X., Kanias, T., Lash, J.P., Molokie, R.E., Oza, B., Lai, C., Rowe, J.H., Gowhari, M., Hassan, J., Desimone, J., Machado, R.F., Gladwin, M.T., Little, J.A. & Gordeuk, V.R. (2014) Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia. British journal of haematology, 164, 729–739.