Serum anti-PLA2R antibodies may be present before clinical manifestations of membranous nephropathy

Kidney International

Volumn 89, Issue 6, 2016, Pages 1399-

  Guerry, Mary Jane ^a   Vanhille, Philippe ^a   Ronco, Pierre ^b,c,d   Debiec, Hanna ^c,d  

^a Valenciennes Hospital   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c INSERM   (France)

^d HÔPITAL TENON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; PHOSPHOLIPASE A2 RECEPTOR ANTIBODY; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG; AUTOANTIBODY; CREATININE; GLUCOCORTICOID; IMMUNOLOGIC FACTOR; IMMUNOSUPPRESSIVE AGENT; PHOSPHOLIPASE A2 RECEPTOR; RITUXIMAB;

AGED; ALBUMIN BLOOD LEVEL; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; CASE REPORT; CLINICAL FEATURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FOCAL GLOMERULOSCLEROSIS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; KIDNEY BIOPSY; LETTER; MALE; MEMBRANOUS GLOMERULONEPHRITIS; PRIORITY JOURNAL; PROTEINURIA; THROMBOPHILIA; BIOPSY; BLOOD; COMBINATION DRUG THERAPY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; KIDNEY; PATHOLOGY; PROCEDURES;

AGED; AUTOANTIBODIES; BIOPSY; CREATININE; CYCLOPHOSPHAMIDE; DRUG THERAPY, COMBINATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GLOMERULONEPHRITIS, MEMBRANOUS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; GLUCOCORTICOIDS; HUMANS; IMMUNOLOGIC FACTORS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; MALE; RECEPTORS, PHOSPHOLIPASE A2; RITUXIMAB;

EID: 84978116665     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2015.11.032     Document Type: Letter

References (3)

1. 1 Beck, L.H. Jr., Bonegio, R.G., Lambeau, G., et al. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 361 (2009), 11–21.
2. 2 van de Logt, A.E., Hofstra, J.M., Wetzels, J.F., Serum anti-PLA2R antibodies can be initially absent in idiopathic membranous nephropathy: seroconversion after prolonged follow-up. Kidney Int 87 (2015), 1263–1264.
3. 3 Fresquet, M., Jowitt, T.A., Gummadova, J., et al. Identification of a major epitope recognized by PLA2R autoantibodies in primary membranous nephropathy. J Am Soc Nephrol 26 (2015), 302–313.