Characterisation of the triple negative breast cancer phenotype associated with the development of central nervous system metastases

ecancermedicalscience

Volumn 10, Issue , 2016, Pages

  Laimito, Katerin Rojas ^a   Gámez Pozo, Angelo ^b   Sepúlveda, Juan ^a   Manso, Luis ^a   López Vacas, Rocío ^c   Pascual, Tomás ^a   Vara, Juan A Fresno ^c   Ciruelos, Eva ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b Biomedica Molecular Medicine   (Spain)

^c HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

Breast cancer; Central nervous system; Metastases; Triple negative

Indexed keywords

ADULT; AGED; ARTICLE; BONE METASTASIS; CANCER ADJUVANT THERAPY; CASE CONTROL STUDY; CENTRAL NERVOUS SYSTEM METASTASIS; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; GENE; GENE EXPRESSION; HBEGF GENE; HUMAN; HUMAN TISSUE; LOCAL METASTASIS; LUNG METASTASIS; MAJOR CLINICAL STUDY; PTGS2 GENE; RETROSPECTIVE STUDY; ST6GALNAC5 GENE; TRIPLE NEGATIVE BREAST CANCER;

EID: 84978055866     PISSN: None     EISSN: 17546605     Source Type: Journal    
DOI: 10.3332/ecancer.2016.632     Document Type: Article

References (45)

1. Smigal C, Jemal A and Ward E et al (2006) Trends in breast cancer by race and ethnicity: update 2006 CA Cancer J Clin 56 168-183 DOI: 10.3322/canjclin.56.3.168 PMID: 16737949
2. Ferlay J, Soerjomataram I and Ervik M et al (2012) Incidencia y mortalidad para todas las edades Prevalencia a 5 años sólo en población adulta GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC
3. Bray F, Ren JS and Masuyer E et al (2013) Estimates of global cancer prevalence for 27 sites in the adult population in 2008 Int J Cancer 132(5) 1133-1145 DOI:10.1002/ijc.27711 Epub 2012 Jul 26
4. Sorlie T, Perou CM and Tibshirani R et al (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci U S A 98 10869-10874 DOI:10.1073/pnas.191367098 PMID: 11553815 PMCID:58566
5. Carey LA, Perou CM and Livasy CA et al (2006) Race, breast cancer subtypes, and survival in the Carolina breast cancer study JAMA 295 2492-2502 DOI:10.1001/jama.295.21.2492 PMID: 16757721
6. Niwinska A, Murawska M and Pogoda K (2010) Breast cancer brain metastases: differences in survival depending on biological subtype, RPA RTOG prognostic class and systemic treatment after whole-brain radiotherapy (WBRT) Ann Oncol 21 942-948 DOI:10.1093/annonc/mdp407
7. Bos PD, Zhang XH and Nadal C et al (2009) Genes that mediate breast cancer metastasis to the brain Nature 459 1005-1009 DOI:10.1038/nature08021 PMID: 19421193 PMCID: 2698953
8. Chambers AF, Groom AC and MacDonald IC (2002) Dissemination and growth of cancer cells in metastatic sites Nat Rev Cancer 2 563-572 DOI:10.1038/nrc865 PMID: 12154349
9. Castaneda CA, Agullo-Ortuno MT and Fresno Vara JA et al (2011) Implication of miRNA in the diagnosis and treatment of breast cancer Expert Rev Anticancer Ther 11 1265-1275 DOI:10.1586/era.11.40 PMID: 21916580
10. Minn AJ, Gupta GP and Siegel PM et al (2005) Genes that mediate breast cancer metastasis to lung Nature 436 518-524 DOI: 10.1038/nature03799 PMID: 16049480 PMCID: 1283098
11. Parker JS, Mullins M and Cheang MC et al (2009) Supervised risk predictor of breast cancer based on intrinsic subtypes J Clin Oncol 27 1160-1167 DOI:10.1200/JCO.2008.18.1370 PMID: 19204204 PMCID: 2667820
12. Lehmann BD, Bauer JA and Chen X et al (2011) Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies J Clin Invest 121 2750-2767 DOI:10.1172/JCI45014 PMID: 21633166 PMCID: 3127435
13. Lachapelle J and Foulkes WD (2011) Triple-negative and basal-like breast cancer: implications for oncologists Curr Oncol 18 161-164 DOI: 10.3747/co.v18i4.824 PMID: 21874112 PMCID: 3149541
14. Reddy KB (2011) Triple-negative breast cancers: an updated review on treatment options Curr Oncol 18:e173-e179 DOI:10.3747/co.v18i4.738 PMID: 21874107 PMCID: 3149549
15. O'Shaughnessy J, Osborne C and Pippen JE et al (2011) Iniparib plus chemotherapy in metastatic triple-negative breast cancer N Engl J Med 364 205-214 DOI:10.1056/NEJMoa1011418
16. Castaneda CA, Cortes-Funes H and Gomez HL et al (2010) The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer Cancer Metastasis Rev 29 751-759 DOI:10.1007/s10555-010-9261-0 PMID: 20922461
17. National Cancer Institute (Access to Investigational Drugs) www.cancer.gov/about-cancer/treatment/drugs/investigational-drugaccess-fact-sheet
18. Lin NU, Bellon JR and Winer EP (2004) CNS metastases in breast cancer J Clin Oncol 22 3608-3617 DOI:10.1200/JCO.2004.01.175 PMID: 15337811
19. Nam BH, Kim SY and Han HS et al (2008) Breast cancer subtypes and survival in patients with brain metastases Breast Cancer Res 10 R20 DOI:10.1186/bcr1870 PMID: 18307763 PMCID: 2374976
20. Deeken JF and Loscher W (2007) The blood-brain barrier and cancer: transporters, treatment, and Trojan horses Clin Cancer Res 13 1663-1674 DOI:10.1158/1078-0432.CCR-06-2854 PMID: 17363519
21. O'Brien KM, Cole SR and Tse CK et al (2010) Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina breast cancer study Clin Cancer Res 16 6100-6110 DOI:10.1158/1078-0432.CCR-10-1533
22. Vallejos CS, Gomez HL and Cruz WR et al (2010) Breast cancer classification according to immunohistochemistry markers: subtypes and association with clinicopathologic variables in a peruvian hospital database Clin Breast Cancer 10 294-300 DOI:10.3816/CBC.2010.n.038 PMID: 20705562
23. Chlebowski RT, Chen Z and Anderson GL et al (2005) Ethnicity and breast cancer: factors influencing differences in incidence and outcome J Natl Cancer Inst 97 439-448 DOI:10.1093/jnci/dji064 PMID: 15770008
24. Gapstur SM, Dupuis J and Gann P et al (1996) Hormone receptor status of breast tumors in black, Hispanic, and non-Hispanic white women An analysis of 13,239 cases Cancer 77 1465-1471 DOI:10.1002/(SICI)1097-0142(19960415)77:8<1465::AIDCNCR7>3.0.CO;2-B PMID: 8608530
25. Li CI, Malone KE and Daling JR (2003) Differences in breast cancer stage, treatment, and survival by race and ethnicity Arch Intern Med 163 49-56 DOI:10.1001/archinte.163.1.49 PMID: 12523916
26. Hausauer AK, Keegan TH and Chang ET et al (2007) Recent breast cancer trends among Asian/Pacific Islander, Hispanic, and African-American women in the US: changes by tumor subtype Breast Cancer Res 9 R90 DOI:10.1186/bcr1839 PMID: 18162138 PMCID: 2246193
27. Parise CA, Bauer KR and Caggiano V (2010) Variation in breast cancer subtypes with age and race/ethnicity Crit Rev Oncol Hematol 76 44-52 DOI:10.1016/j.critrevonc.2009.09.002
28. Shavers VL, Harlan LC and Stevens JL (2003) Racial/ethnic variation in clinical presentation, treatment, and survival among breast cancer patients under age 35 Cancer 97 134-147 DOI:10.1002/cncr.11051
29. Gonzalez Burchard E, Borrell LN and Choudhry S et al (2005) Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research Am J Public Health 95 2161-2168 DOI: 10.2105/AJPH.2005.068668 PMID: 16257940 PMCID: 1449501
30. Millikan RC, Newman B and Tse CK et al (2008) Epidemiology of basal-like breast cancer Breast Cancer Res Treat 109 123-139 DOI:10.1007/s10549-007-9632-6 PMCID: 2443103
31. Pike MC, Kolonel LN and Henderson BE et al (2002) Breast cancer in a multiethnic cohort in Hawaii and Los Angeles: risk factoradjusted incidence in Japanese equals and in Hawaiians exceeds that in Whites Cancer Epidemiol Biomarkers Prev 11 795-800 PMID: 12223421
32. Probst-Hensch NM, Pike MC and McKean-Cowdin R et al (2000) Ethnic differences in post-menopausal plasma oestrogen levels: high oestrone levels in Japanese-American women despite low weight Br J Cancer 82 1867-1870 DOI:10.1054/bjoc.1999.1082 PMID: 10839304 PMCID: 2363216
33. Looker AC, Dawson-Hughes B and Calvo MS et al (2002) Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III Bone 30 771-777 DOI:10.1016/S8756-3282(02)00692-0 PMID: 11996918
34. Hsieh MM, Everhart JE and Byrd-Holt DD et al (2007) Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences Ann Intern Med 146 486-492 DOI: 10.7326/0003-4819-146-7-200704030-00004 PMID: 17404350
35. Castaneda CA GH, Vallejos C and Cortes-Funes et al (2011) Comparison between Spanish and Peruvian Patients with early breast cancer In: San Antonio Breast Cancer Meeting
36. Heitz F, Harter P and Lueck HJ et al (2009) Triple-negative and HER2-overexpressing breast cancer exhibit an elevated risk and an earlier occurrence of cerebral metastases Eur J Cancer 45 2792-2798 DOI:10.1016/j.ejca.2009.06.027 PMID: 19643597
37. Foulkes WD, Smith IE and Reis-Filho JS Triple-negative breast cancer N England 363 1938-1948
38. Don X, Nguyen, Paula D Bos and Joan Massagué (2009) Metastasis: from dissemination to organ-specific colonization Nature Rev Cancer 9 274-284 DOI:10.1038/nrc2622
39. Bollig-Fischer A, Michelhaugh SK and Ali-Fehmi R et al (2013) The molecular genomics of metastatic brain tumours OA Mol Oncol 1(1) 6
40. Brastianos PK, Carter SL and Santagata S et al (2015) Genomic characterization of brain metastases reveals branched evolution and potencial therapeutic targets Cancer Discov 5(11) 1-14 DOI:10.1158/2159-8290.CD-15-0369
41. Sartorius CA, Hanna CT and Grill B et al (2015) Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism Oncogene 28 1-12 DOI:10.1038/onc.2015.353 PMID: 26411365
42. Salhia B, Kiefer J and Ross JT et al (2014) Integrated genomic and epigenomic analysis of breast cancer brain metastasis PLoS One 9 e85448 DOI:10.1371/journal.pone.0085448 PMID: 24489661 PMCID: 3906004
43. Stirzaker C, Zotenko E and Song JZ et al (2015) Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value Nat Commun 6 5899 DOI:10.1038/ncomms6899 PMID: 25641231
44. Chalmers AJ (2010) Overcoming resistance of Glioblastoma to conventional cytotoxic therapies by the addition of PARP inhibitors Anticancer Agents Med Chem 10 520-533 DOI: 10.2174/187152010793498627 PMID: 20879987
45. Sánchez-Navarro I, Gámez-Pozo A and González-Barón M et al (2010) Comparison of gene expression profiling by reverse transcription quantitative PCR between fresh frozen and formalin-fixed, paraffin-embedded breast cancer tissues Biotechniques 48(5) 389-97 DOI: 10.2144/000113388