Circulating omentin as a novel biomarker for colorectal cancer risk: Data from the EPIC-potsdam cohort study

Cancer Research

Volumn 76, Issue 13, 2016, Pages 3862-3871

  Aleksandrova, Krasimira ^a   Di Giuseppe, Romina ^b   Isermann, Berend ^c   Biemann, Ronald ^c   Schulze, Matthias ^a,d,e   Wittenbecher, Clemens ^a,d   Fritsche, Andreas ^d,f   Lehmann, Rainer ^d,g   Menzel, Juliane ^a,d,h   Weikert, Cornelia ^a,e,h,i   Pischon, Tobias ^j   Boeing, Heiner ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d German Center of Diabetes Research (DZD)   (Germany)

^e DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^f UNIVERSITY OF TÜBINGEN   (Germany)

^g UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^h CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

ⁱ FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^j MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; OMENTIN; TUMOR MARKER; UNCLASSIFIED DRUG; CYTOKINE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; ITLN1 PROTEIN, HUMAN; LECTIN;

ADULT; AGE; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CANCER RISK; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIASTOLIC BLOOD PRESSURE; DIET; EDUCATION; FEMALE; FOOD INTAKE; GENDER; HUMAN; ICD-10; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; OBESITY; OXIDATIVE STRESS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SYSTOLIC BLOOD PRESSURE; TRANSCRIPTION REGULATION; WAIST CIRCUMFERENCE; BLOOD; CANCER STAGING; CASE CONTROL STUDY; CAUCASIAN; COLORECTAL NEOPLASMS; COMPARATIVE STUDY; COMPLICATION; FOLLOW UP; MIDDLE AGED; PROGNOSIS; RISK FACTOR;

ADIPOSITY; ADULT; BIOMARKERS, TUMOR; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CYTOKINES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLLOW-UP STUDIES; GPI-LINKED PROTEINS; HUMANS; LECTINS; LIFE STYLE; MALE; MIDDLE AGED; NEOPLASM STAGING; OBESITY; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84977577737     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-3464     Document Type: Article

References (45)

1. Yang RZ, Lee MJ, Hu H, Pray J, Wu HB, Hansen BC, et al. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab 2006;290:E1253-61.
2. Jaikanth C, Gurumurthy P, Cherian KM, Indhumathi T. Emergence of omentin as a pleiotropic adipocytokine. Exp Clin Endocrinol Diabetes 2013;121:377-83.
3. Suzuki YA, Shin K, Lonnerdal B. Molecular cloning and functional expression of a human intestinal lactoferrin receptor. Biochemistry 2001;40: 15771-9.
4. Tsuji S, Uehori J, Matsumoto M, Suzuki Y, Matsuhisa A, Toyoshima K, et al. Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall. J Biol Chem 2001;276:23456-63.
5. Lee JK, Schnee J, Pang M, Wolfert M, Baum LG, Moremen KW, et al. Human homologs of the Xenopus oocyte cortical granule lectin XL35. Glycobiology 2001;11:65-73.
6. Schaffler A, Neumeier M, Herfarth H, Furst A, Scholmerich J, Buchler C. Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue. Biochim Biophys Acta 2005; 1732:96-102.
7. Gong L, Bai B, Chen J. [Omentin: a new adipokine]. Sheng Li Ke Xue Jin Zhan 2011;42:390-3.
8. Washimi K, Yokose T, Yamashita M, Kageyama T, Suzuki K, Yoshihara M, et al. Specific expression of human intelectin-1 in malignant pleural mesothelioma and gastrointestinal goblet cells. PLoS One 2012;7: e39889.
9. de Souza Batista CM, Yang RZ, Lee MJ, Glynn NM, Yu DZ, Pray J, et al. Omentin plasma levels and gene expression are decreased in obesity. Diabetes 2007;56:1655-61.
10. Zhou JY, Chan L, Zhou SW. Omentin: linking metabolic syndrome and cardiovascular disease. Curr Vasc Pharmacol 2014;12:136-43.
11. Shang FJ, Wang JP, Liu XT, Zheng QS, Xue YS, Wang B, et al. Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome. Biomarkers 2011;16:657-62.
12. Shibata R, Ouchi N, Kikuchi R, Takahashi R, Takeshita K, Kataoka Y, et al. Circulating omentin is associated with coronary artery disease in men. Atherosclerosis 2011;219:811-4.
13. Tan BK, Adya R, Randeva HS. Omentin: a novel link between inflammation, diabesity, and cardiovascular disease. Trends Cardiovasc Med 2010; 20:143-8.
14. El-Mesallamy HO, El-Derany MO, Hamdy NM. Serum omentin-1 and chemerin levels are interrelated in patients with Type 2 diabetes mellitus with or without ischaemic heart disease. Diabetic Med 2011;28:1194-200.
15. Wali A, Siddiq F, Kanakapalli D, Liu Z, Lonardo F, Rishi AK, et al. Intelectin overexpression causes chromosomal aberrations in immortalized human mesothelial cells. Proc Amer Assoc Cancer Res 2006;47:2544.
16. Tan BK, Adya R, Farhatullah S, Chen J, Lehnert H, Randeva HS. Metformin treatment may increase omentin-1 levels in women with polycystic ovary syndrome. Diabetes 2010;59:3023-31.
17. Wu SS, Liang QH, Liu Y, Cui RR, Yuan LQ, Liao EY. Omentin-1 stimulates human osteoblast proliferation through PI3K/Akt signal pathway. Int J Endocrinol 2013;2013:368970.
18. Fazeli MS, Dashti H, Akbarzadeh S, Assadi M, Aminian A, Keramati MR, et al. Circulating levels of novel adipocytokines in patients with colorectal cancer. Cytokine 2013;62:81-5.
19. Peebles RS Jr. The intelectins: a new link between the immune response to parasitic infections and allergic inflammation? Am J Physiol Lung Cell Mol Physiol 2010;298:L288-9.
20. Aleksandrova K, Boeing H, Jenab M, Bas Bueno-de-Mesquita H, Jansen E, van Duijnhoven FJ, et al. Metabolic syndrome and risks of colon and rectal cancer: the European prospective investigation into cancer and nutrition study. Cancer Prev Res 2011;4:1873-83.
21. Aleksandrova K, Jenab M, Bueno-de-Mesquita HB, Fedirko V, Kaaks R, Lukanova A, et al. Biomarker patterns of inflammatory and metabolic pathways are associated with risk of colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Epidemiol 2014;29:261-75.
22. Aleksandrova K, Jenab M, Boeing H, Jansen E, Bueno-de-Mesquita HB, Rinaldi S, et al. Circulating C-reactive protein concentrations and risks of colon and rectal cancer: a nested case-control study within the European Prospective Investigation into Cancer and Nutrition. Am J Epidemiol 2010;172:407-18.
23. Boeing H, Wahrendorf J, Becker N. EPIC-Germany-A source for studies into diet and risk of chronic diseases. European Investigation into Cancer and Nutrition. Ann Nutr Metab 1999;43:195-204.
24. Kroke A, Klipstein-Grobusch K, Voss S, Möseneder J, Thielecke F, Noack R, et al. Validation of a self-administered food-frequency questionnaire administered in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: comparison of energy, protein, and macronutrient intakes estimated with the doubly labeled water, urinary nitrogen, and repeated 24-h dietary recall methods. Am J Clin Nutr 1999;70:439-47.
25. Boeing H, Korfmann A, Bergmann MM. Recruitment procedures of EPIC Germany. European Investigation into Cancer and Nutrition. Ann Nutr Metab 1999;43:205-15.
26. Kroke A, Bergmann MM, Lotze G, Jeckel A, Klipstein-Grobusch K, Boeing H. Measures of quality control in the German component of the EPIC study. European Prospective Investigation into Cancer and Nutrition. Ann Nutr Metab 1999;43:216-24.
27. Bramer GR. International statistical classification of diseases and related health problems. Tenth revision. World Health Stat Q 1988;41:32-6.
28. WHO. International classification of diseases for oncology. 2nd ed. Geneva, Switzerland: WHO;1990.
29. Prentice RL. A case-cohort design for epidemiologic cohort studies and disease prevention trials. Biometrika 1986;73:1-11.
30. Sharp SJ, Poulaliou M, Thompson SG, White IR, Wood AM. A review of published analyses of case-cohort studies and recommendations for future reporting. PLoS One 2014;9:e101176.
31. Wittenbecher C, di Giuseppe R, Biemann R, Menzel J, Arregui M, Hoffmann J, et al. Reproducibility of retinol binding protein 4 and omentin-1 measurements over a four months period: a reliability study in a cohort of 207 apparently healthy participants. PLoS One 2015;10: e0138480.
32. Enzenbach C, Kroger J, Zietemann V, Jansen EH, Fritsche A, Doring F, et al. Erythrocytemembrane phospholipid polyunsaturated fatty acids are related to plasma C-reactive protein and adiponectin in middle-aged German women and men. Eur J Nutr 2011;50:625-36.
33. Jacobs S, Kroger J, Floegel A, Boeing H, Drogan D, Pischon T, et al. Evaluation of various biomarkers as potential mediators of the association between coffee consumption and incident type 2 diabetes in the EPIC-Potsdam Study. Am J Clin Nutr 2014;100: 891-900.
34. Prentice RL, Pyke R. Logistic diseaseincidence models and case-control studies. Biometrika 1979;66:403-11.
35. Uyeturk U, Sarici H, Kin Tekce B, Eroglu M, Kemahli E, Uyeturk U, et al. Serum omentin level in patients with prostate cancer. Med Oncol 2014; 31:923.
36. Pino MS, Chung DC. The chromosomal instability pathway in colon cancer. Gastroenterology 2010;138:2059-72.
37. Whitman M, Kaplan DR, Schaffhausen B, Cantley L, Roberts TM. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 1985;315:239-42.
38. Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501.
39. Jang MJ, Jeon YJ, Kim JW, Chong SY, Hong SP, Oh D, et al. Association of eNOS polymorphisms (-786T>C, 4a4b, 894G>T) with colorectal cancer susceptibility in the Korean population. Gene 2013;512:275-81.
40. Wesener DA, Wangkanont K, McBride R, Song X, Kraft MB, Hodges HL, et al. Recognition of microbial glycans by human intelectin-1. Nat Struct Mol Biol 2015;22:603-10.
41. Yu D. Omentin activates AMP-activated protein kinase and plays a role in energymetabolism and immune response. Baltimore:University of Maryland; 2011. 108p.
42. Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40:955-62.
43. Moreno-Navarrete JM, Catalan V, Ortega F, Gomez-Ambrosi J, Ricart W, Fruhbeck G, et al. Circulating omentin concentration increases after weight loss. Nutr Metab 2010;7:27.
44. Tan BK, Adya R, Farhatullah S, Lewandowski KC, O'Hare P, Lehnert H, et al. Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose. Diabetes 2008;57:801-8.
45. Aleksandrova K, Nimptsch K, Pischon T. Influence of obesity and related metabolic alterations on colorectal cancer risk. Curr Nutr Rep 2013;2:1-9.