Live Staphylococcus aureus induces expression and release of vascular endothelial growth factor in terminally differentiated mouse mast cells

Frontiers in Immunology

Volumn 7, Issue JUN, 2016, Pages

  Johnzon, Carl Fredrik ^a   Rönnberg, Elin ^b   Guss, Bengt ^a   Pejler, Gunnar ^a,b  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Mast cells; NF B; Peritoneal cavity; Staphylococcusaureus; VEGF family

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BACTERIAL CELL WALL; CELL INTERACTION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE INDUCTION; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MAST CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; STAPHYLOCOCCUS AUREUS; UPREGULATION;

EID: 84977544900     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2016.00247     Document Type: Article

References (32)

1. Abraham SN, St John AL. Mast cell-orchestrated immunity to pathogens. Nat Rev (2010) 10:440-52. doi:10.1038/nri2782
2. Gri G, Frossi B, D'Inca F, Danelli L, Betto E, Mion F, et al. Mast cell: an emerging partner in immune interaction. Front Immunol (2012) 3:120. doi:10.3389/fimmu.2012.00120
3. Wernersson S, Pejler G. Mast cell granules: armed for battle. Nat Rev Immunol (2014) 14:478-94. doi:10.1038/nri3690
4. Forsythe P. Microbes taming mast cells: implications for allergic inflammation and beyond. Eur J Pharmacol (2016) 778:169-75. doi:10.1016/j.ejphar.2015.06.034
5. Johnzon CF, Rönnberg E, Pejler G. The role of mast cells in bacterial infection. Am J Pathol (2016) 186:4-14. doi:10.1016/j.ajpath.2015.06.024
6. Tlsty TD, Coussens LM. Tumor stroma and regulation of cancer development. Annu Rev Pathol (2006) 1:119-50. doi:10.1146/annurev.pathol.1.110304.100224
7. Marichal T, Tsai M, Galli SJ. Mast cells: potential positive and negative roles in tumor biology. Cancer Immunol Res (2013) 1:269-79. doi:10.1158/2326-6066.CIR-13-0119
8. Rigoni A, Colombo MP, Pucillo C. The role of mast cells in molding the tumor microenvironment. Cancer Microenviron (2014) 8:167-76. doi:10.1007/s12307-014-0152-8
9. Byrne AM, Bouchier-Hayes DJ, Harmey JH. Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Mol Med (2005) 9:777-94. doi:10.1111/j.1582-4934.2005.tb00379.x
10. Hoeben A, Landuyt B, Highley MS, Wildiers H, Van Oosterom AT, De Bruijn EA. Vascular endothelial growth factor and angiogenesis. Pharmacol Rev (2004) 56:549-80. doi:10.1124/pr.56.4.3
11. Boesiger J, Tsai M, Maurer M, Yamaguchi M, Brown LF, Claffey KP, et al. Mast cells can secrete vascular permeability factor/vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of fc epsilon receptor I expression. J Exp Med (1998) 188:1135-45. doi:10.1084/jem.188.6.1135
12. Grutzkau A, Kruger-Krasagakes S, Baumeister H, Schwarz C, Kogel H, Welker P, et al. Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206. Mol Biol Cell (1998) 9:875-84. doi:10.1091/mbc.9.4.875
13. Abdel-Majid RM, Marshall JS. Prostaglandin E2 induces degranulation-independent production of vascular endothelial growth factor by human mast cells. J Immunol (2004) 172:1227-36. doi:10.4049/jimmunol.172.2.1227
14. Detoraki A, Staiano RI, Granata F, Giannattasio G, Prevete N, de Paulis A, et al. Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects. J Allergy Clin Immunol (2009) 123:1142-9. doi:10.1016/j.jaci.2009.01.044
15. Rönnberg E, Johnzon CF, Calounova G, Garcia Faroldi G, Grujic M, Hartmann K, et al. Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivo. Immunology (2014) 143:155-63. doi:10.1111/imm.12297
16. Malbec O, Roget K, Schiffer C, Iannascoli B, Dumas AR, Arock M, et al. Peritoneal cell-derived mast cells: an in vitro model of mature serosal-type mouse mast cells. J Immunol (2007) 178:6465-75. doi:10.4049/jimmunol.178.10.6465
17. Rönnberg E, Pejler G. Serglycin: the master of the mast cell. Methods Mol Biol (2012) 836:201-17. doi:10.1007/978-1-61779-498-8_14
18. Rönnberg E, Calounova G, Guss B, Lundequist A, Pejler G. Granzyme D is a novel murine mast cell protease that is highly induced by multiple pathways of mast cell activation. Infect Immun (2013) 81:2085-94. doi:10.1128/IAI.00290-13
19. Klein M, Klein-Hessling S, Palmetshofer A, Serfling E, Tertilt C, Bopp T, et al. Specific and redundant roles for NFAT transcription factors in the expression of mast cell-derived cytokines. J Immunol (2006) 177:6667-74. doi:10.4049/jimmunol.177.10.6667
20. Voehringer D. Protective and pathological roles of mast cells and basophils. Nat Rev Immunol (2013) 13:362-75. doi:10.1038/nri3427
21. Galli SJ, Nakae S, Tsai M. Mast cells in the development of adaptive immune responses. Nat Immunol (2005) 6:135-42. doi:10.1038/ni1158
22. Sawatsubashi M, Yamada T, Fukushima N, Mizokami H, Tokunaga O, Shin T. Association of vascular endothelial growth factor and mast cells with angiogenesis in laryngeal squamous cell carcinoma. Virchows Arch (2000) 436:243-8. doi:10.1007/s004280050037
23. Toth-Jakatics R, Jimi S, Takebayashi S, Kawamoto N. Cutaneous malignant melanoma: correlation between neovascularization and peritumor accumulation of mast cells overexpressing vascular endothelial growth factor. Hum Pathol (2000) 31:955-60. doi:10.1053/hupa.2000.16658
24. Imada A, Shijubo N, Kojima H, Abe S. Mast cells correlate with angiogenesis and poor outcome in stage I lung adenocarcinoma. Eur Respir J (2000) 15:1087-93. doi:10.1034/j.1399-3003.2000.01517.x
25. Aoki M, Pawankar R, Niimi Y, Kawana S. Mast cells in basal cell carcinoma express VEGF, IL-8 and RANTES. Int Arch Allergy Immunol (2003) 130:216-23. doi:10.1159/000069515
26. Cummins J, Tangney M. Bacteria and tumours: causative agents or opportunistic inhabitants? Infect Agent Cancer (2013) 8:11. doi:10.1186/1750-9378-8-11
27. Marshall JS. Mast-cell responses to pathogens. Nat Rev Immunol (2004) 4:787-99. doi:10.1038/nri1460
28. Supajatura V, Ushio H, Nakao A, Akira S, Okumura K, Ra C, et al. Differential responses of mast cell toll-like receptors 2 and 4 in allergy and innate immunity. J Clin Invest (2002) 109:1351-9. doi:10.1172/JCI0214704
29. Ikeda T, Funaba M. Altered function of murine mast cells in response to lipopolysaccharide and peptidoglycan. Immunol Lett (2003) 88:21-6. doi:10.1016/S0165-2478(03)00031-2
30. Mrabet-Dahbi S, Metz M, Dudeck A, Zuberbier T, Maurer M. Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. Exp Dermatol (2009) 18:437-44. doi:10.1111/j.1600-0625.2009.00878.x
31. Qiao H, Andrade MV, Lisboa FA, Morgan K, Beaven MA. FcepsilonR1 and toll-like receptors mediate synergistic signals to markedly augment production of inflammatory cytokines in murine mast cells. Blood (2006) 107:610-8. doi:10.1182/blood-2005-06-2271
32. Sandig H, Bulfone-Paus S. TLR signaling in mast cells: common and unique features. Front Immunol (2012) 3:185. doi:10.3389/fimmu.2012.00185