Mutations of cystic fibrosis transmembrane conductance regulator gene cause a monocyte-selective adhesion deficiency

American Journal of Respiratory and Critical Care Medicine

Volumn 193, Issue 10, 2016, Pages 1123-1133

  Sorio, Claudio ^a   Montresor, Alessio ^a   Bolomini Vittori, Matteo ^a,b   Caldrer, Sara ^a   Rossi, Barbara ^a   Dusi, Silvia ^a   Angiari, Stefano ^a   Johansson, Jan E ^a   Vezzalini, Marzia ^a   Leal, Teresinha ^c   Calcaterra, Elisa ^a   Assael, Baroukh M ^d   Melotti, Paola ^d   Laudanna, Carlo ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^d UNIVERSITY HOSPITAL OF VERONA   (Italy)

Author keywords

Cell adhesion; Cystic fibrosis; Integrins; Leukocyte trafficking; Lung inflammation

Indexed keywords

BETA1 INTEGRIN; CD18 ANTIGEN; CHEMOATTRACTANT; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PROTEIN CDC42; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION ASSAY; CHEMOTAXIS ASSAY; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; INNATE IMMUNITY; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LUNG ALVEOLUS; LUNG PARENCHYMA; MALE; MIDDLE AGED; MONOCYTE; MONONUCLEAR CELL; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; YOUNG ADULT; ANIMAL; C57BL MOUSE; CELL ADHESION; DISEASE MODEL; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; LEUKOCYTE; METABOLISM; MUTATION;

ANIMALS; CELL ADHESION; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; MONOCYTES; MUTATION;

EID: 84977509961     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201510-1922OC     Document Type: Article

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