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84920939338
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Sulkowski MS, Gardiner DF, Rodriguez-Torres M, Reddy KR, Hassanein T, Jacobson I, et al. Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection. N Engl J Med. 2014;370(3):211–21.
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Daclatasvir plus Sofosbuvir for HCV in patients coinfected with HIV-1
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COI: 1:CAS:528:DC%2BC28XpslOltA%3D%3D, PID: 26196502, An important clinical trial for current therapeutic options
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Wyles DL, Ruane PJ, Sulkowski MS, Dieterich D, Luetkemeyer A, Morgan TR, et al. Daclatasvir plus Sofosbuvir for HCV in patients coinfected with HIV-1. N Engl J Med. 2015;373(8):714–25. An important clinical trial for current therapeutic options.
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25
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Sustained virologic response of 100% in HCV genotype 1b patients with cirrhosis receiving ombitasvir/Paritaprevir/r and Dasabuvir for 12 Weeks
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Jacobson IM, Gordon SC, Kowdley KV, Yoshida EM, Rodriguez-Torres M, Sulkowski MS, et al. Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options. N Engl J Med. 2013;368(20):1867–77.
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COI: 1:CAS:528:DC%2BC2MXhslamsrbP, PID: 26248087, An interesting trial highlighting that there may still be a role for interferon-based therapy in treating genotype 3 cirrhotic patients who have been shown to have poor response to DAA combinations
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Foster GR, Pianko S, Brown A, Forton D, Nahass RG, George J, et al. Efficacy of sofosbuvir plus ribavirin with or without peginterferon-alfa in patients with hepatitis C virus genotype 3 infection and treatment-experienced patients with cirrhosis and hepatitis C virus genotype 2 infection. Gastroenterology. 2015;149(6):1462–70. An interesting trial highlighting that there may still be a role for interferon-based therapy in treating genotype 3 cirrhotic patients who have been shown to have poor response to DAA combinations.
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