Sensitivity analysis for missing data in regulatory submissions

Statistics in Medicine

Volumn 35, Issue 17, 2016, Pages 2876-2879

  Permutt, Thomas ^a  

^a Center for Drug Evaluation and Research   (United States)

Author keywords

missing data; sensitivity analysis; tipping point

Indexed keywords

CONSENSUS DEVELOPMENT; DECISION MAKING; GOVERNMENT; HUMAN;

EID: 84977475688     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.6753     Document Type: Article

References (3)

1. National Research Council. The Prevention and Treatment of Missing Data in Clinical Trials. National Academies Press: Washington, 2010.
2. European Medicines Agency. Guideline on adjustment for baseline covariates (draft), 2013. (Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2013/06/WC500144946.pdf) [Accessed on 27 October 2015].
3. Kenward MG. The handling of missing data in clinical trials. Clinical Investigation. 2013; 3(3): 241–250.