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Volumn 45, Issue 2, 2016, Pages 285-301

Pregnancy and the Patient with Inflammatory Bowel Disease: Fertility, Treatment, Delivery, and Complications

Author keywords

Breast feeding; Crohn disease; Drug related side effects and adverse reactions; Fertility; Inflammatory bowel disease; Obstetric delivery; Pregnancy; Ulcerative colitis

Indexed keywords

ADALIMUMAB; AMOXICILLIN PLUS CLAVULANIC ACID; AZATHIOPRINE; BALSALAZIDE; BUDESONIDE; CERTOLIZUMAB PEGOL; CIPROFLOXACIN; CORTICOSTEROID; CYCLOSPORIN; GOLIMUMAB; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; METRONIDAZOLE; NATALIZUMAB; OLSALAZINE; PREDNISONE; SALAZOSULFAPYRIDINE; TIOGUANINE; TOFACITINIB; TUMOR NECROSIS FACTOR INHIBITOR; USTEKINUMAB; VEDOLIZUMAB; AMINOSALICYLIC ACID DERIVATIVE; ANTIINFECTIVE AGENT; BIOLOGICAL PRODUCT; GASTROINTESTINAL AGENT; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY;

EID: 84977178278     PISSN: 08898553     EISSN: 15581942     Source Type: Journal    
DOI: 10.1016/j.gtc.2016.02.006     Document Type: Review
Times cited : (55)

References (95)
  • 1
    • 36549001139 scopus 로고    scopus 로고
    • The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States
    • Kappelman M.D., Rifas-Shiman S.L., Kleinman K., et al. The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Clin Gastroenterol Hepatol 2007, 5:1424-1429.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1424-1429
    • Kappelman, M.D.1    Rifas-Shiman, S.L.2    Kleinman, K.3
  • 2
    • 34249100277 scopus 로고    scopus 로고
    • Voluntary childlessness is increased in women with inflammatory bowel disease
    • Marri S.R., Ahn C., Buchman A.L. Voluntary childlessness is increased in women with inflammatory bowel disease. Inflamm Bowel Dis 2007, 13:591-599.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 591-599
    • Marri, S.R.1    Ahn, C.2    Buchman, A.L.3
  • 3
    • 84884908411 scopus 로고    scopus 로고
    • Systematic review: fertility in non-surgically treated inflammatory bowel disease
    • Tavernier N., Fumery M., Peyrin-Biroulet L., et al. Systematic review: fertility in non-surgically treated inflammatory bowel disease. Aliment Pharmacol Ther 2013, 38:847-853.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 847-853
    • Tavernier, N.1    Fumery, M.2    Peyrin-Biroulet, L.3
  • 4
    • 84877043649 scopus 로고    scopus 로고
    • Inflammatory bowel disease and pregnancy: lack of knowledge is associated with negative views
    • Selinger C.P., Eaden J., Selby W., et al. Inflammatory bowel disease and pregnancy: lack of knowledge is associated with negative views. J Crohns Colitis 2013, 7:e206-e213.
    • (2013) J Crohns Colitis , vol.7 , pp. e206-e213
    • Selinger, C.P.1    Eaden, J.2    Selby, W.3
  • 5
    • 67650314408 scopus 로고    scopus 로고
    • Fear and fertility in inflammatory bowel disease: a mismatch of perception and reality affects family planning decisions
    • Mountifield R., Bampton P., Prosser R., et al. Fear and fertility in inflammatory bowel disease: a mismatch of perception and reality affects family planning decisions. Inflamm Bowel Dis 2009, 15:720-725.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 720-725
    • Mountifield, R.1    Bampton, P.2    Prosser, R.3
  • 6
    • 0036142477 scopus 로고    scopus 로고
    • Ulcerative colitis: female fecundity before diagnosis, during disease, and after surgery compared with a population sample
    • Ording Olsen K., Juul S., Berndtsson I., et al. Ulcerative colitis: female fecundity before diagnosis, during disease, and after surgery compared with a population sample. Gastroenterology 2002, 122:15-19.
    • (2002) Gastroenterology , vol.122 , pp. 15-19
    • Ording Olsen, K.1    Juul, S.2    Berndtsson, I.3
  • 8
    • 84940792863 scopus 로고    scopus 로고
    • Decreased fertility rates in 9639 women diagnosed with inflammatory bowel disease: a United Kingdom population-based cohort study
    • Ban L., Tata L.J., Humes D.J., et al. Decreased fertility rates in 9639 women diagnosed with inflammatory bowel disease: a United Kingdom population-based cohort study. Aliment Pharmacol Ther 2015, 42:855-866.
    • (2015) Aliment Pharmacol Ther , vol.42 , pp. 855-866
    • Ban, L.1    Tata, L.J.2    Humes, D.J.3
  • 9
    • 33846187247 scopus 로고    scopus 로고
    • Sexual function in persons with inflammatory bowel disease: a survey with matched controls
    • Timmer A., Bauer A., Dignass A., et al. Sexual function in persons with inflammatory bowel disease: a survey with matched controls. Clin Gastroenterol Hepatol 2007, 5:87-94.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 87-94
    • Timmer, A.1    Bauer, A.2    Dignass, A.3
  • 10
    • 84872500019 scopus 로고    scopus 로고
    • Serum anti-Mullerian hormone levels are lower in reproductive-age women with Crohn's disease compared to healthy control women
    • Senates E., Colak Y., Erdem E.D., et al. Serum anti-Mullerian hormone levels are lower in reproductive-age women with Crohn's disease compared to healthy control women. J Crohns Colitis 2013, 7:e29-e34.
    • (2013) J Crohns Colitis , vol.7 , pp. e29-e34
    • Senates, E.1    Colak, Y.2    Erdem, E.D.3
  • 11
    • 33750343586 scopus 로고    scopus 로고
    • Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis
    • Waljee A., Waljee J., Morris A.M., et al. Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis. Gut 2006, 55:1575-1580.
    • (2006) Gut , vol.55 , pp. 1575-1580
    • Waljee, A.1    Waljee, J.2    Morris, A.M.3
  • 12
    • 84880569749 scopus 로고    scopus 로고
    • A total laparoscopic approach reduces the infertility rate after ileal pouch-anal anastomosis: a 2-center study
    • Beyer-Berjot L., Maggiori L., Birnbaum D., et al. A total laparoscopic approach reduces the infertility rate after ileal pouch-anal anastomosis: a 2-center study. Ann Surg 2013, 258:275-282.
    • (2013) Ann Surg , vol.258 , pp. 275-282
    • Beyer-Berjot, L.1    Maggiori, L.2    Birnbaum, D.3
  • 13
    • 33744940577 scopus 로고    scopus 로고
    • Colectomy with ileorectal anastomosis preserves female fertility in ulcerative colitis
    • Mortier P.E., Gambiez L., Karoui M., et al. Colectomy with ileorectal anastomosis preserves female fertility in ulcerative colitis. Gastroenterol Clin Biol 2006, 30:594-597.
    • (2006) Gastroenterol Clin Biol , vol.30 , pp. 594-597
    • Mortier, P.E.1    Gambiez, L.2    Karoui, M.3
  • 14
    • 84930759735 scopus 로고    scopus 로고
    • In vitro fertilization is successful in women with ulcerative colitis and ileal pouch anal anastomosis
    • Pabby V., Oza S.S., Dodge L.E., et al. In vitro fertilization is successful in women with ulcerative colitis and ileal pouch anal anastomosis. Am J Gastroenterol 2015, 110:792-797.
    • (2015) Am J Gastroenterol , vol.110 , pp. 792-797
    • Pabby, V.1    Oza, S.S.2    Dodge, L.E.3
  • 15
    • 84910018241 scopus 로고    scopus 로고
    • Vitamin D deficiency and infertility: insights from in vitro fertilization cycles
    • Paffoni A., Ferrari S., Vigano P., et al. Vitamin D deficiency and infertility: insights from in vitro fertilization cycles. J Clin Endocrinol Metab 2014, 99:E2372-E2376.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E2372-E2376
    • Paffoni, A.1    Ferrari, S.2    Vigano, P.3
  • 16
    • 84877848035 scopus 로고    scopus 로고
    • Increased prevalence of celiac disease in patients with unexplained infertility in the United States
    • Choi J.M., Lebwohl B., Wang J., et al. Increased prevalence of celiac disease in patients with unexplained infertility in the United States. J Reprod Med 2011, 56:199-203.
    • (2011) J Reprod Med , vol.56 , pp. 199-203
    • Choi, J.M.1    Lebwohl, B.2    Wang, J.3
  • 17
    • 0346216970 scopus 로고    scopus 로고
    • Zinc deficiency in men with Crohn's disease may contribute to poor sperm function and male infertility
    • El-Tawil A.M. Zinc deficiency in men with Crohn's disease may contribute to poor sperm function and male infertility. Andrologia 2003, 35:337-341.
    • (2003) Andrologia , vol.35 , pp. 337-341
    • El-Tawil, A.M.1
  • 18
    • 0019413993 scopus 로고
    • Sulphasalazine and male infertility: reversibility and possible mechanism
    • Toovey S., Hudson E., Hendry W.F., et al. Sulphasalazine and male infertility: reversibility and possible mechanism. Gut 1981, 22:445-451.
    • (1981) Gut , vol.22 , pp. 445-451
    • Toovey, S.1    Hudson, E.2    Hendry, W.F.3
  • 19
    • 0037532941 scopus 로고    scopus 로고
    • Effect of methotrexate on male fertility
    • French A.E., Koren G. Effect of methotrexate on male fertility. Can Fam Physician 2003, 49:577-578.
    • (2003) Can Fam Physician , vol.49 , pp. 577-578
    • French, A.E.1    Koren, G.2
  • 20
    • 9444242676 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) promotes cell survival during spermatogenesis, and this effect can be blocked by infliximab, a TNF-alpha antagonist
    • Suominen J.S., Wang Y., Kaipia A., et al. Tumor necrosis factor-alpha (TNF-alpha) promotes cell survival during spermatogenesis, and this effect can be blocked by infliximab, a TNF-alpha antagonist. Eur J Endocrinol 2004, 151:629-640.
    • (2004) Eur J Endocrinol , vol.151 , pp. 629-640
    • Suominen, J.S.1    Wang, Y.2    Kaipia, A.3
  • 21
    • 17444372061 scopus 로고    scopus 로고
    • Infliximab and semen quality in men with inflammatory bowel disease
    • Mahadevan U., Terdiman J.P., Aron J., et al. Infliximab and semen quality in men with inflammatory bowel disease. Inflamm Bowel Dis 2005, 11:395-399.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 395-399
    • Mahadevan, U.1    Terdiman, J.P.2    Aron, J.3
  • 22
    • 84939567997 scopus 로고    scopus 로고
    • Inflammatory bowel disease increases risk of adverse pregnancy outcomes: a meta-analysis
    • O'Toole A., Nwanne O., Tomlinson T. Inflammatory bowel disease increases risk of adverse pregnancy outcomes: a meta-analysis. Dig Dis Sci 2015, 60:2750-2761.
    • (2015) Dig Dis Sci , vol.60 , pp. 2750-2761
    • O'Toole, A.1    Nwanne, O.2    Tomlinson, T.3
  • 23
    • 79951607827 scopus 로고    scopus 로고
    • Congenital abnormalities and other birth outcomes in children born to women with ulcerative colitis in Denmark and Sweden
    • Stephansson O., Larsson H., Pedersen L., et al. Congenital abnormalities and other birth outcomes in children born to women with ulcerative colitis in Denmark and Sweden. Inflamm Bowel Dis 2011, 17:795-801.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 795-801
    • Stephansson, O.1    Larsson, H.2    Pedersen, L.3
  • 24
    • 84890799984 scopus 로고    scopus 로고
    • Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications
    • Ban L., Tata L.J., Fiaschi L., et al. Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications. Gastroenterology 2014, 146:76-84.
    • (2014) Gastroenterology , vol.146 , pp. 76-84
    • Ban, L.1    Tata, L.J.2    Fiaschi, L.3
  • 25
    • 34848818286 scopus 로고    scopus 로고
    • Pregnancy outcomes in women with inflammatory bowel disease: a large community-based study from Northern California
    • Mahadevan U., Sandborn W.J., Li D.K., et al. Pregnancy outcomes in women with inflammatory bowel disease: a large community-based study from Northern California. Gastroenterology 2007, 133:1106-1112.
    • (2007) Gastroenterology , vol.133 , pp. 1106-1112
    • Mahadevan, U.1    Sandborn, W.J.2    Li, D.K.3
  • 26
    • 84939220186 scopus 로고    scopus 로고
    • Inflammatory bowel disease and risk of adverse pregnancy outcomes
    • Boyd H.A., Basit S., Harpsoe M.C., et al. Inflammatory bowel disease and risk of adverse pregnancy outcomes. PLoS One 2015, 10:e0129567.
    • (2015) PLoS One , vol.10
    • Boyd, H.A.1    Basit, S.2    Harpsoe, M.C.3
  • 27
    • 84867676372 scopus 로고    scopus 로고
    • Complications from inflammatory bowel disease during pregnancy and delivery
    • Broms G., Granath F., Linder M., et al. Complications from inflammatory bowel disease during pregnancy and delivery. Clin Gastroenterol Hepatol 2012, 10:1246-1252.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 1246-1252
    • Broms, G.1    Granath, F.2    Linder, M.3
  • 28
    • 84867499432 scopus 로고    scopus 로고
    • Inflammatory bowel disease: risk factors for adverse pregnancy outcome and the impact of maternal weight gain
    • Oron G., Yogev Y., Shcolnick S., et al. Inflammatory bowel disease: risk factors for adverse pregnancy outcome and the impact of maternal weight gain. J Matern Fetal Neonatal Med 2012, 25:2256-2260.
    • (2012) J Matern Fetal Neonatal Med , vol.25 , pp. 2256-2260
    • Oron, G.1    Yogev, Y.2    Shcolnick, S.3
  • 29
    • 84954454550 scopus 로고    scopus 로고
    • Insufficient weight gain during pregnancy in maternal IBD predicts adverse pregnancy outcomes: results from the PIANO and Norwegian registry
    • S-238, [abstract]
    • Bengtson M., Martin C.F., Aamodt G., et al. Insufficient weight gain during pregnancy in maternal IBD predicts adverse pregnancy outcomes: results from the PIANO and Norwegian registry. Gastroenterology 2015, 148:S-238. [abstract].
    • (2015) Gastroenterology , vol.148
    • Bengtson, M.1    Martin, C.F.2    Aamodt, G.3
  • 31
    • 0033761324 scopus 로고    scopus 로고
    • Birth outcomes of women with ulcerative colitis: a nationwide Danish cohort study
    • Norgard B., Fonager K., Sorensen H.T., et al. Birth outcomes of women with ulcerative colitis: a nationwide Danish cohort study. Am J Gastroenterol 2000, 95:3165-3170.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3165-3170
    • Norgard, B.1    Fonager, K.2    Sorensen, H.T.3
  • 32
    • 34548119104 scopus 로고    scopus 로고
    • Disease activity in pregnant women with Crohn's disease and birth outcomes: a regional Danish cohort study
    • Norgard B., Hundborg H.H., Jacobsen B.A., et al. Disease activity in pregnant women with Crohn's disease and birth outcomes: a regional Danish cohort study. Am J Gastroenterol 2007, 102:1947-1954.
    • (2007) Am J Gastroenterol , vol.102 , pp. 1947-1954
    • Norgard, B.1    Hundborg, H.H.2    Jacobsen, B.A.3
  • 33
    • 43549086187 scopus 로고    scopus 로고
    • Relapses of inflammatory bowel disease during pregnancy: in-hospital management and birth outcomes
    • Reddy D., Murphy S.J., Kane S.V., et al. Relapses of inflammatory bowel disease during pregnancy: in-hospital management and birth outcomes. Am J Gastroenterol 2008, 103:1203-1209.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1203-1209
    • Reddy, D.1    Murphy, S.J.2    Kane, S.V.3
  • 34
    • 84902130328 scopus 로고    scopus 로고
    • Birth outcomes in women with inflammatory bowel disease: effects of disease activity and drug exposure
    • Broms G., Granath F., Linder M., et al. Birth outcomes in women with inflammatory bowel disease: effects of disease activity and drug exposure. Inflamm Bowel Dis 2014, 20:1091-1098.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1091-1098
    • Broms, G.1    Granath, F.2    Linder, M.3
  • 36
    • 80052449320 scopus 로고    scopus 로고
    • Pregnancy outcome in inflammatory bowel disease: prospective European case-control ECCO-EpiCom study, 2003-2006
    • Bortoli A., Pedersen N., Duricova D., et al. Pregnancy outcome in inflammatory bowel disease: prospective European case-control ECCO-EpiCom study, 2003-2006. Aliment Pharmacol Ther 2011, 34:724-734.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 724-734
    • Bortoli, A.1    Pedersen, N.2    Duricova, D.3
  • 37
    • 84882453590 scopus 로고    scopus 로고
    • The course of inflammatory bowel disease during pregnancy and postpartum: a prospective European ECCO-EpiCom Study of 209 pregnant women
    • Pedersen N., Bortoli A., Duricova D., et al. The course of inflammatory bowel disease during pregnancy and postpartum: a prospective European ECCO-EpiCom Study of 209 pregnant women. Aliment Pharmacol Ther 2013, 38:501-512.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 501-512
    • Pedersen, N.1    Bortoli, A.2    Duricova, D.3
  • 38
    • 84866755429 scopus 로고    scopus 로고
    • PIANO: a 1000 patient prospective registry of pregnancy outcomes in women with IBD exposed to immunomodulators and biologic therapy
    • [abstract]
    • Mahadevan U., Martin C.F., Sandler R.S., et al. PIANO: a 1000 patient prospective registry of pregnancy outcomes in women with IBD exposed to immunomodulators and biologic therapy. Gastroenterology 2012, 142:S-149. [abstract].
    • (2012) Gastroenterology , vol.142 , pp. S149
    • Mahadevan, U.1    Martin, C.F.2    Sandler, R.S.3
  • 39
    • 84862004167 scopus 로고    scopus 로고
    • Inflammatory bowel disease and pregnancy: overlapping pathways
    • Nasef N.A., Ferguson L.R. Inflammatory bowel disease and pregnancy: overlapping pathways. Transl Res 2012, 160:65-83.
    • (2012) Transl Res , vol.160 , pp. 65-83
    • Nasef, N.A.1    Ferguson, L.R.2
  • 40
    • 84882452332 scopus 로고    scopus 로고
    • Meta-analysis: the impact of disease activity at conception on disease activity during pregnancy in patients with inflammatory bowel disease
    • Abhyankar A., Ham M., Moss A.C. Meta-analysis: the impact of disease activity at conception on disease activity during pregnancy in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2013, 38:460-466.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 460-466
    • Abhyankar, A.1    Ham, M.2    Moss, A.C.3
  • 41
    • 84904433790 scopus 로고    scopus 로고
    • Self-reported adherence to medical treatment, breastfeeding behaviour, and disease activity during the postpartum period in women with Crohn's disease
    • Julsgaard M., Norgaard M., Hvas C.L., et al. Self-reported adherence to medical treatment, breastfeeding behaviour, and disease activity during the postpartum period in women with Crohn's disease. Scand J Gastroenterol 2014, 49:958-966.
    • (2014) Scand J Gastroenterol , vol.49 , pp. 958-966
    • Julsgaard, M.1    Norgaard, M.2    Hvas, C.L.3
  • 42
    • 84878007818 scopus 로고    scopus 로고
    • Importance of appropriate pharmaceutical management in pregnant women with ulcerative colitis
    • Ujihara M., Ando T., Ishiguro K., et al. Importance of appropriate pharmaceutical management in pregnant women with ulcerative colitis. BMC Res Notes 2013, 6:210.
    • (2013) BMC Res Notes , vol.6 , pp. 210
    • Ujihara, M.1    Ando, T.2    Ishiguro, K.3
  • 43
    • 60949090682 scopus 로고    scopus 로고
    • Outcomes of obstetric hospitalizations among women with inflammatory bowel disease in the United States
    • Nguyen G.C., Boudreau H., Harris M.L., et al. Outcomes of obstetric hospitalizations among women with inflammatory bowel disease in the United States. Clin Gastroenterol Hepatol 2009, 7:329-334.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 329-334
    • Nguyen, G.C.1    Boudreau, H.2    Harris, M.L.3
  • 44
    • 84908385246 scopus 로고    scopus 로고
    • Exposure to anti-TNFα therapy in the third trimester of pregnancy is not associated with increased adverse outcomes: results from the PIANO registry
    • [abstract]
    • Mahadevan U., Martin C.F., Dubinsky M., et al. Exposure to anti-TNFα therapy in the third trimester of pregnancy is not associated with increased adverse outcomes: results from the PIANO registry. Gastroenterology 2014, 146:S-170. [abstract].
    • (2014) Gastroenterology , vol.146 , pp. S170
    • Mahadevan, U.1    Martin, C.F.2    Dubinsky, M.3
  • 45
    • 84921783728 scopus 로고    scopus 로고
    • Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases
    • Ananthakrishnan A.N., Cheng A., Cagan A., et al. Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases. Dig Dis Sci 2015, 60:471-477.
    • (2015) Dig Dis Sci , vol.60 , pp. 471-477
    • Ananthakrishnan, A.N.1    Cheng, A.2    Cagan, A.3
  • 46
    • 84905497735 scopus 로고    scopus 로고
    • Impact of mode of delivery on outcomes in patients with perianal Crohn's disease
    • Cheng A.G., Oxford E.C., Sauk J., et al. Impact of mode of delivery on outcomes in patients with perianal Crohn's disease. Inflamm Bowel Dis 2014, 20:1391-1398.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1391-1398
    • Cheng, A.G.1    Oxford, E.C.2    Sauk, J.3
  • 47
    • 34447618017 scopus 로고    scopus 로고
    • The effect of restorative proctocolectomy on sexual function, urinary function, fertility, pregnancy and delivery: a systematic review
    • Cornish J.A., Tan E., Teare J., et al. The effect of restorative proctocolectomy on sexual function, urinary function, fertility, pregnancy and delivery: a systematic review. Dis Colon Rectum 2007, 50:1128-1138.
    • (2007) Dis Colon Rectum , vol.50 , pp. 1128-1138
    • Cornish, J.A.1    Tan, E.2    Teare, J.3
  • 48
    • 84905506300 scopus 로고    scopus 로고
    • Mode of delivery and risk of inflammatory bowel disease in the offspring: systematic review and meta-analysis of observational studies
    • Bruce A., Black M., Bhattacharya S. Mode of delivery and risk of inflammatory bowel disease in the offspring: systematic review and meta-analysis of observational studies. Inflamm Bowel Dis 2014, 20:1217-1226.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1217-1226
    • Bruce, A.1    Black, M.2    Bhattacharya, S.3
  • 49
    • 0027404560 scopus 로고
    • Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews
    • Yang H., McElree C., Roth M.P., et al. Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. Gut 1993, 34:517-524.
    • (1993) Gut , vol.34 , pp. 517-524
    • Yang, H.1    McElree, C.2    Roth, M.P.3
  • 50
    • 0025897609 scopus 로고
    • Frequency of inflammatory bowel disease in offspring of couples both presenting with inflammatory bowel disease
    • Bennett R.A., Rubin P.H., Present D.H. Frequency of inflammatory bowel disease in offspring of couples both presenting with inflammatory bowel disease. Gastroenterology 1991, 100:1638-1643.
    • (1991) Gastroenterology , vol.100 , pp. 1638-1643
    • Bennett, R.A.1    Rubin, P.H.2    Present, D.H.3
  • 51
    • 84904467388 scopus 로고    scopus 로고
    • It IS worth the effort: patient knowledge of reproductive aspects of inflammatory bowel disease improves dramatically after a single group education session
    • Mountifield R., Andrews J.M., Bampton P. It IS worth the effort: patient knowledge of reproductive aspects of inflammatory bowel disease improves dramatically after a single group education session. J Crohns Colitis 2014, 8:796-801.
    • (2014) J Crohns Colitis , vol.8 , pp. 796-801
    • Mountifield, R.1    Andrews, J.M.2    Bampton, P.3
  • 52
    • 84907159739 scopus 로고    scopus 로고
    • Content and format of labeling for human prescription drug and biological products; requirements for pregnancy and lactation labeling
    • [Federal Register Web site], Accessed October 24, 2015.
    • Food and Drug Administration. Content and format of labeling for human prescription drug and biological products; requirements for pregnancy and lactation labeling [Federal Register Web site]. 2014. Available at: . Accessed October 24, 2015. http://federalregister.gov/a/2014-28241.
    • (2014)
  • 53
    • 0037302567 scopus 로고    scopus 로고
    • Birth outcome in women exposed to 5-aminosalicylic acid during pregnancy: a Danish cohort study
    • Norgard B., Fonager K., Pedersen L., et al. Birth outcome in women exposed to 5-aminosalicylic acid during pregnancy: a Danish cohort study. Gut 2003, 52:243-247.
    • (2003) Gut , vol.52 , pp. 243-247
    • Norgard, B.1    Fonager, K.2    Pedersen, L.3
  • 54
    • 84887535627 scopus 로고    scopus 로고
    • Presence of phthalates in gastrointestinal medications: is there a hidden danger?
    • Gallinger Z.R., Nguyen G.C. Presence of phthalates in gastrointestinal medications: is there a hidden danger?. World J Gastroenterol 2013, 19:7042-7047.
    • (2013) World J Gastroenterol , vol.19 , pp. 7042-7047
    • Gallinger, Z.R.1    Nguyen, G.C.2
  • 55
    • 0024563241 scopus 로고
    • Diarrhoea due to 5-aminosalicylic acid in breast milk
    • Nelis G.F. Diarrhoea due to 5-aminosalicylic acid in breast milk. Lancet 1989, 1:383.
    • (1989) Lancet , vol.1 , pp. 383
    • Nelis, G.F.1
  • 56
    • 70350181571 scopus 로고    scopus 로고
    • Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding)
    • Martinez Lopez J.A., Loza E., Carmona L. Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding). Clin Exp Rheumatol 2009, 27:678-684.
    • (2009) Clin Exp Rheumatol , vol.27 , pp. 678-684
    • Martinez Lopez, J.A.1    Loza, E.2    Carmona, L.3
  • 58
    • 0036255563 scopus 로고    scopus 로고
    • Teratogen update: azathioprine and 6-mercaptopurine
    • Polifka J.E., Friedman J.M. Teratogen update: azathioprine and 6-mercaptopurine. Teratology 2002, 65:240-261.
    • (2002) Teratology , vol.65 , pp. 240-261
    • Polifka, J.E.1    Friedman, J.M.2
  • 59
    • 84893752804 scopus 로고    scopus 로고
    • Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease
    • Jharap B., de Boer N.K., Stokkers P., et al. Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease. Gut 2014, 63:451-457.
    • (2014) Gut , vol.63 , pp. 451-457
    • Jharap, B.1    de Boer, N.K.2    Stokkers, P.3
  • 60
    • 78651075520 scopus 로고    scopus 로고
    • Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study
    • Coelho J., Beaugerie L., Colombel J.F., et al. Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study. Gut 2011, 60:198-203.
    • (2011) Gut , vol.60 , pp. 198-203
    • Coelho, J.1    Beaugerie, L.2    Colombel, J.F.3
  • 61
    • 84875214914 scopus 로고    scopus 로고
    • Safety of thiopurines and anti-TNF-alpha drugs during pregnancy in patients with inflammatory bowel disease
    • Casanova M.J., Chaparro M., Domenech E., et al. Safety of thiopurines and anti-TNF-alpha drugs during pregnancy in patients with inflammatory bowel disease. Am J Gastroenterol 2013, 108:433-440.
    • (2013) Am J Gastroenterol , vol.108 , pp. 433-440
    • Casanova, M.J.1    Chaparro, M.2    Domenech, E.3
  • 62
    • 84873284779 scopus 로고    scopus 로고
    • Systematic review and meta-analysis on the effects of thiopurines on birth outcomes from female and male patients with inflammatory bowel disease
    • Akbari M., Shah S., Velayos F.S., et al. Systematic review and meta-analysis on the effects of thiopurines on birth outcomes from female and male patients with inflammatory bowel disease. Inflamm Bowel Dis 2013, 19:15-22.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 15-22
    • Akbari, M.1    Shah, S.2    Velayos, F.S.3
  • 63
    • 84871496472 scopus 로고    scopus 로고
    • The fetal safety of thiopurines for the treatment of inflammatory bowel disease in pregnancy
    • Hutson J.R., Matlow J.N., Moretti M.E., et al. The fetal safety of thiopurines for the treatment of inflammatory bowel disease in pregnancy. J Obstet Gynaecol 2013, 33:1-8.
    • (2013) J Obstet Gynaecol , vol.33 , pp. 1-8
    • Hutson, J.R.1    Matlow, J.N.2    Moretti, M.E.3
  • 64
    • 84908385247 scopus 로고    scopus 로고
    • Achievement of developmental milestones among offspring of women with inflammatory bowel disease: the PIANO registry
    • [abstract]
    • Mahadevan U., Martin C.F., Chambers C., et al. Achievement of developmental milestones among offspring of women with inflammatory bowel disease: the PIANO registry. Gastroenterology 2014, 146:S-1. [abstract].
    • (2014) Gastroenterology , vol.146 , pp. S1
    • Mahadevan, U.1    Martin, C.F.2    Chambers, C.3
  • 66
    • 84964660329 scopus 로고    scopus 로고
    • Use of immunomodulators and biologics before, during, and after pregnancy
    • McConnell R.A., Mahadevan U. Use of immunomodulators and biologics before, during, and after pregnancy. Inflamm Bowel Dis 2016, 22(1):213-223.
    • (2016) Inflamm Bowel Dis , vol.22 , Issue.1 , pp. 213-223
    • McConnell, R.A.1    Mahadevan, U.2
  • 67
    • 84866122837 scopus 로고    scopus 로고
    • Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT registry
    • Lichtenstein G.R., Feagan B.G., Cohen R.D., et al. Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT registry. Am J Gastroenterol 2012, 107:1409-1422.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1409-1422
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.D.3
  • 68
    • 78649232947 scopus 로고    scopus 로고
    • Safety of adalimumab in Crohn's disease during pregnancy: case report and review of the literature
    • Jurgens M., Brand S., Filik L., et al. Safety of adalimumab in Crohn's disease during pregnancy: case report and review of the literature. Inflamm Bowel Dis 2010, 16:1634-1636.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 1634-1636
    • Jurgens, M.1    Brand, S.2    Filik, L.3
  • 69
    • 84964658103 scopus 로고    scopus 로고
    • Pregnancy outcomes after exposure to certolizumab pegol: updated results from safety surveillance
    • [abstract]
    • Mahadevan U., Vermeire S., Wolf D.C., et al. Pregnancy outcomes after exposure to certolizumab pegol: updated results from safety surveillance. Gastroenterology 2015, 148:S-858-S-859. [abstract].
    • (2015) Gastroenterology , vol.148 , pp. S858-S859
    • Mahadevan, U.1    Vermeire, S.2    Wolf, D.C.3
  • 70
    • 84880949345 scopus 로고    scopus 로고
    • Safety of TNF-alpha inhibitors during IBD pregnancy: a systematic review
    • Nielsen O.H., Loftus E.V., Jess T. Safety of TNF-alpha inhibitors during IBD pregnancy: a systematic review. BMC Med 2013, 11:174.
    • (2013) BMC Med , vol.11 , pp. 174
    • Nielsen, O.H.1    Loftus, E.V.2    Jess, T.3
  • 71
    • 84925534298 scopus 로고    scopus 로고
    • Anti-TNFalpha therapies are safe during pregnancy in women with inflammatory bowel disease: a systematic review and meta-analysis
    • Narula N., Al-Dabbagh R., Dhillon A., et al. Anti-TNFalpha therapies are safe during pregnancy in women with inflammatory bowel disease: a systematic review and meta-analysis. Inflamm Bowel Dis 2014, 20:1862-1869.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1862-1869
    • Narula, N.1    Al-Dabbagh, R.2    Dhillon, A.3
  • 72
    • 84964634492 scopus 로고    scopus 로고
    • Detection of biologic agents in breast milk and implication for infection, growth and development in infants born to women with inflammatory bowel disease: results from the PIANO registry
    • [abstract]
    • Matro R., Martin C.F., Wolf D.C., et al. Detection of biologic agents in breast milk and implication for infection, growth and development in infants born to women with inflammatory bowel disease: results from the PIANO registry. Gastroenterology 2015, 148:S-141. [abstract].
    • (2015) Gastroenterology , vol.148 , pp. S141
    • Matro, R.1    Martin, C.F.2    Wolf, D.C.3
  • 73
    • 84874576191 scopus 로고    scopus 로고
    • Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease
    • Mahadevan U., Wolf D.C., Dubinsky M., et al. Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2013, 11:286-292.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 286-292
    • Mahadevan, U.1    Wolf, D.C.2    Dubinsky, M.3
  • 74
    • 60749119300 scopus 로고    scopus 로고
    • Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy
    • Kane S.V., Acquah L.A. Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy. Am J Gastroenterol 2009, 104:228-233.
    • (2009) Am J Gastroenterol , vol.104 , pp. 228-233
    • Kane, S.V.1    Acquah, L.A.2
  • 75
    • 84978620885 scopus 로고    scopus 로고
    • Adalimumab and infliximab levels in neonates (ERA Study)
    • [abstract]
    • Julsgaard M., Christensen L.A., Gibson P.R., et al. Adalimumab and infliximab levels in neonates (ERA Study). Gastroenterology 2015, 148:S-108. [abstract].
    • (2015) Gastroenterology , vol.148 , pp. S108
    • Julsgaard, M.1    Christensen, L.A.2    Gibson, P.R.3
  • 76
    • 79953795330 scopus 로고    scopus 로고
    • TNF-alpha and the development of the neonatal immune system: implications for inhibitor use in pregnancy
    • Arsenescu R., Arsenescu V., de Villiers W.J. TNF-alpha and the development of the neonatal immune system: implications for inhibitor use in pregnancy. Am J Gastroenterol 2011, 106:559-562.
    • (2011) Am J Gastroenterol , vol.106 , pp. 559-562
    • Arsenescu, R.1    Arsenescu, V.2    de Villiers, W.J.3
  • 77
    • 84897389359 scopus 로고    scopus 로고
    • Impact of anti-tumor necrosis factor alpha antibodies administered to pregnant women with inflammatory bowel disease on long-term outcome of exposed children
    • Bortlik M., Duricova D., Machkova N., et al. Impact of anti-tumor necrosis factor alpha antibodies administered to pregnant women with inflammatory bowel disease on long-term outcome of exposed children. Inflamm Bowel Dis 2014, 20:495-501.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 495-501
    • Bortlik, M.1    Duricova, D.2    Machkova, N.3
  • 78
    • 79751472857 scopus 로고    scopus 로고
    • The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organisation: pregnancy and pediatrics
    • [quiz: 224]
    • Mahadevan U., Cucchiara S., Hyams J.S., et al. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organisation: pregnancy and pediatrics. Am J Gastroenterol 2011, 106:214-223. [quiz: 224].
    • (2011) Am J Gastroenterol , vol.106 , pp. 214-223
    • Mahadevan, U.1    Cucchiara, S.2    Hyams, J.S.3
  • 79
    • 84874569090 scopus 로고    scopus 로고
    • Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure
    • Zelinkova Z., van der Ent C., Bruin K.F., et al. Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure. Clin Gastroenterol Hepatol 2013, 11:318-321.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 318-321
    • Zelinkova, Z.1    van der Ent, C.2    Bruin, K.F.3
  • 80
    • 84923090375 scopus 로고    scopus 로고
    • Pregnancy and fetal outcomes following natalizumab exposure in pregnancy. A prospective, controlled observational study
    • Ebrahimi N., Herbstritt S., Gold R., et al. Pregnancy and fetal outcomes following natalizumab exposure in pregnancy. A prospective, controlled observational study. Mult Scler 2015, 21:198-205.
    • (2015) Mult Scler , vol.21 , pp. 198-205
    • Ebrahimi, N.1    Herbstritt, S.2    Gold, R.3
  • 81
    • 84937701525 scopus 로고    scopus 로고
    • Vedolizumab exposure in pregnancy: outcomes from clinical studies in inflammatory bowel disease
    • [abstract]
    • Dubinsky M., Mahadevan U., Vermeire S., et al. Vedolizumab exposure in pregnancy: outcomes from clinical studies in inflammatory bowel disease. J Crohns Colitis 2015, 9:S361-S362. [abstract].
    • (2015) J Crohns Colitis , vol.9 , pp. S361-S362
    • Dubinsky, M.1    Mahadevan, U.2    Vermeire, S.3
  • 82
    • 84977162841 scopus 로고    scopus 로고
    • Pregnancy outcomes in women exposed to ustekinumab in the psoriasis clinical development program
    • [abstract]
    • Schaufelberg B.W., Horn E., Cather J.C., et al. Pregnancy outcomes in women exposed to ustekinumab in the psoriasis clinical development program. J Am Acad Dermatol 2014, 70:AB178. [abstract].
    • (2014) J Am Acad Dermatol , vol.70 , pp. AB178
    • Schaufelberg, B.W.1    Horn, E.2    Cather, J.C.3
  • 83
    • 84977164379 scopus 로고    scopus 로고
    • Pregnancy outcomes in the tofacitinib RA safety database through April 2014
    • [abstract]
    • Marren A., Chen Y., Frazier D., et al. Pregnancy outcomes in the tofacitinib RA safety database through April 2014. Ann Rheum Dis 2015, 74:256-257. [abstract].
    • (2015) Ann Rheum Dis , vol.74 , pp. 256-257
    • Marren, A.1    Chen, Y.2    Frazier, D.3
  • 84
    • 0033662284 scopus 로고    scopus 로고
    • Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies
    • Park-Wyllie L., Mazzotta P., Pastuszak A., et al. Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies. Teratology 2000, 62:385-392.
    • (2000) Teratology , vol.62 , pp. 385-392
    • Park-Wyllie, L.1    Mazzotta, P.2    Pastuszak, A.3
  • 85
    • 79955140407 scopus 로고    scopus 로고
    • Corticosteroid use during pregnancy and risk of orofacial clefts
    • Hviid A., Molgaard-Nielsen D. Corticosteroid use during pregnancy and risk of orofacial clefts. CMAJ 2011, 183:796-804.
    • (2011) CMAJ , vol.183 , pp. 796-804
    • Hviid, A.1    Molgaard-Nielsen, D.2
  • 86
    • 84912092945 scopus 로고    scopus 로고
    • Pregnancy outcomes amongst mothers with inflammatory bowel disease exposed to systemic corticosteroids: results of the PIANO registry
    • [abstract]
    • Lin K., Martin C.F., Dassopoulos T., et al. Pregnancy outcomes amongst mothers with inflammatory bowel disease exposed to systemic corticosteroids: results of the PIANO registry. Gastroenterology 2014, 146:S-1. [abstract].
    • (2014) Gastroenterology , vol.146 , pp. S1
    • Lin, K.1    Martin, C.F.2    Dassopoulos, T.3
  • 89
  • 91
    • 0031938752 scopus 로고    scopus 로고
    • A population based case-control teratologic study of oral metronidazole treatment during pregnancy
    • Czeizel A.E., Rockenbauer M. A population based case-control teratologic study of oral metronidazole treatment during pregnancy. Br J Obstet Gynaecol 1998, 105:322-327.
    • (1998) Br J Obstet Gynaecol , vol.105 , pp. 322-327
    • Czeizel, A.E.1    Rockenbauer, M.2
  • 92
    • 0034947676 scopus 로고    scopus 로고
    • Augmentin treatment during pregnancy and the prevalence of congenital abnormalities: a population-based case-control teratologic study
    • Czeizel A.E., Rockenbauer M., Sorensen H.T., et al. Augmentin treatment during pregnancy and the prevalence of congenital abnormalities: a population-based case-control teratologic study. Eur J Obstet Gynecol Reprod Biol 2001, 97:188-192.
    • (2001) Eur J Obstet Gynecol Reprod Biol , vol.97 , pp. 188-192
    • Czeizel, A.E.1    Rockenbauer, M.2    Sorensen, H.T.3
  • 93
    • 84858729223 scopus 로고    scopus 로고
    • ACOG committee opinion No. 474: nonobstetric surgery during pregnancy
    • ACOG Committee on Obstetric Practice ACOG committee opinion No. 474: nonobstetric surgery during pregnancy. Obstet Gynecol 2011, 117:420-421.
    • (2011) Obstet Gynecol , vol.117 , pp. 420-421
  • 94
    • 29244490035 scopus 로고    scopus 로고
    • Maternal and fetal outcome after colectomy for fulminant ulcerative colitis during pregnancy: case series and literature review
    • Dozois E.J., Wolff B.G., Tremaine W.J., et al. Maternal and fetal outcome after colectomy for fulminant ulcerative colitis during pregnancy: case series and literature review. Dis Colon Rectum 2006, 49:64-73.
    • (2006) Dis Colon Rectum , vol.49 , pp. 64-73
    • Dozois, E.J.1    Wolff, B.G.2    Tremaine, W.J.3
  • 95
    • 69249211059 scopus 로고    scopus 로고
    • Systematic review: the role of breastfeeding in the development of pediatric inflammatory bowel disease
    • Barclay A.R., Russell R.K., Wilson M.L., et al. Systematic review: the role of breastfeeding in the development of pediatric inflammatory bowel disease. J Pediatr 2009, 155:421-426.
    • (2009) J Pediatr , vol.155 , pp. 421-426
    • Barclay, A.R.1    Russell, R.K.2    Wilson, M.L.3


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