Traditional Chinese medicine Guizhi Fuling capsule used for therapy of dysmenorrhea via attenuating uterus contraction

Journal of Ethnopharmacology

Volumn 191, Issue , 2016, Pages 273-279

  Sun, Lan ^a,b   Liu, Lina ^b   Zong, Shaobo ^b   Wang, Zhengzhong ^b   Zhou, Jun ^b   Xu, Zhiliang ^b   Ding, Gang ^b   Xiao, Wei ^b   Kou, Junping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b JIANGSU KANION PHARMACEUTICAL CO   (China)

Author keywords

Ca2+; Guizhi Fuling capsule; Primary dysmenorrhea; Uterine contraction; Uterine smooth muscle cells

Indexed keywords

CALCIUM ION; CHINESE DRUG; CYCLOOXYGENASE 2; ESTRADIOL BENZOATE; GUIZHI FULING; NITRIC OXIDE; OXYTOCIN; OXYTOCIN RECEPTOR; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG; CALCIUM; CHOLINERGIC RECEPTOR BLOCKING AGENT; ESTRADIOL; ESTRADIOL 3-BENZOATE; GUIZHI-FULING; HERBACEOUS AGENT; OXTR PROTEIN, MOUSE; OXYTOCIC AGENT; PTGS2 PROTEIN, MOUSE; UTERUS SPASMOLYTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CHINESE MEDICINE; DRUG CAPSULE; DRUG MECHANISM; DYSMENORRHEA; FEEDING; FEMALE; IC50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; UTERINE TISSUE; UTERUS CONTRACTION; ANALOGS AND DERIVATIVES; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PATHOPHYSIOLOGY; UTERUS;

ANIMALS; CALCIUM; CYCLOOXYGENASE 2; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; DYSMENORRHEA; ESTRADIOL; FEMALE; IN VITRO TECHNIQUES; MICE, INBRED ICR; NITRIC OXIDE; OXYTOCICS; OXYTOCIN; PARASYMPATHOLYTICS; RECEPTORS, OXYTOCIN; TOCOLYTIC AGENTS; UTERINE CONTRACTION; UTERUS;

EID: 84976616577     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.06.042     Document Type: Article

References (29)

1. Burton, W.N., Morrison, A., Wertheimer, A.I., Pharmaceuticals and worker productivity loss: a critical review of the literature. J. Occup. Environ. Med. 45:6 (2003), 610–621.
2. Bernstein, K., Vink, J.Y., Fu, X.W., Wakita, H., Danielsson, J., Wapner, R., Gallos, G., Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility. Am. J. Obstet. Gynecol., 211(6), 2014 (688-e1).
3. Calixto, J.B., Yunes, R.A., Rae, G.A., Effect of crude extracts from Leonotis nepetifolia (Labiatae) on rat and guinea-pig smooth muscle and rat cardiac muscle. J. Pharm. Pharmacol. 43:8 (1991), 529–534.
4. Chen, Y., Cao, Y., Xie, Y., Zhang, X., Yang, Q., Li, X., Wang, S., Traditional Chinese medicine for the treatment of primary dysmenorrhea: how do Yuanhu painkillers effectively treat dysmenorrhea?. Phytomedicine 20:12 (2013), 1095–1104.
5. Filler, W.W., Hall, W.C., Dysmenorrhea and its therapy: a uterine contractility study. Obstet. Gynecol. Surv. 25:8 (1970), 778–780.
6. Fenakel, K., Lurie, S., The use of calcium channel blockers in obstetrics and gynecology, a review. Eur. J. Obstet. Gynecol. Reprod. Biol. 37:3 (1990), 199–203.
7. Fuchs, A.R., Ivell, R., Ganz, N., Fields, M.J., Gimenez, T., Secretion of oxytocin in pregnant and parturient cows: corpus luteum may contribute to plasma oxytocin at term. Biol. Reprod. 65:4 (2001), 1135–1141.
8. French, L., Dysmenorrhea. Am. Fam. Phys. 71:2 (2005), 285–291.
9. Halbert, D.R., Demers, L.M., A clinical trial of indomethacin and ibuprofen in dysmenorrhea. J. Reprod. Med. 21:4 (1978), 219–222.
10. Hsu, C.S., Yang, J.K., Yang, L.L., Effect of a dysmenorrhea Chinese medicinal prescription on uterus contractility in vitro. Phytother. Res. 17:7 (2003), 778–783.
11. Hu, C.D., Zhang, J., Pharmacological effects and synthetical progress of paeonol. Chem. Bioeng., 8, 2009, 008.
12. He, D.Y., Dai, S.M., Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine. Front. Pharmacol., 2, 2011, 10.
13. Kokjohn, K., Schmid, D.M., Triano, J.J., Brennan, P.C., The effect of spinal manipulation on pain and prostaglandin levels in women with primary dysmenorrhea. J. Manip. Physiol. Ther. 15:5 (1992), 279–285.
14. Kaplan, Ö., Nazıroğlu, M., Güney, M., Aykur, M., Non-steroidal anti-inflammatory drug modulates oxidative stress and calcium ion levels in the neutrophils of patients with primary dysmenorrhea. J. Reprod. Immunol. 100:2 (2013), 87–92.
15. Lumsden, M.A., Kelly, R.W., Baird, D.T., Primary dysmenorrhoea: the importance of both prostaglandins E2 and F2α. J. Obstet. Gynaecol. 90:12 (1983), 1135–1140.
16. Lefebvre, G., Pinsonneault, O., Antao, V., Black, A., Burnett, M., Feldman, K., Robert, M., Primary dysmenorrhea consensus guideline. J. Obstet. Gynaecol. Can. 27:12 (2005), 1117–1146.
17. Liu, Y.J., Xiao, W., Wang, Z.Z., Zhao, B.J., Zhou, Z.M., Jiang, H.Z., Jin, Z., Wei, S.B., Wang, Z., Wang, D.M., Xia, Q.H., Lin, J., Wang, Q., Effects and safety of varying doses of Guizhi Fuling capsule in patients with primary dysmenorrheal: a multi-center, randomized, double-blind, placebo-controlled clinical study. China J. Chin. Mater. Med. 38:12 (2013), 2019–2022.
18. Moya, R.A., Moisa, C.F., Morales, F., Wynter, H., Ali, A., Narancio, E., Transdermal glyceryl trinitrate in the management of primary dysmenorrhea. Int. J. Gynecol. Obstet. 69:2 (2000), 113–118.
19. Powell, A.M., Chan, W.Y., Alvin, P., Litt, I.F., Menstrual-PGF2α, PGE2 and TXA2 in normal and dysmenorrheic women and their temporal relationship to dysmenorrhea. Prostaglandins 29:2 (1985), 273–289.
20. Rudolph, M.I., de los Angeles García, M., Sepulveda, M., Brandan, E., Reinicke, K., Nicovani, S., Villan, L., Ethodin: pharmacological evidence of the interaction between smooth muscle and mast cells in the myometrium. J. Pharmacol. Exp. Ther. 282:1 (1997), 256–261.
21. Shikano, K., Ohlstein, E.H., Berkowitz, B.A., Differential selectivity of endothelium-derived relaxing factor and nitric oxide in smooth muscle. Br. J. Pharmacol. 92:3 (1987), 483–485.
22. Sales, K.J., Jabbour, H.N., Cyclooxygenase enzymes and prostaglandins in pathology of the endometrium. Reproduction 126:5 (2003), 559–567.
23. Viero, C., Shibuya, I., Kitamura, N., Verkhratsky, A., Fujihara, H., Katoh, A., Dayanithi, G., Oxytocin: crossing the bridge between basic science and pharmacotherapy. CNS Neurosci. Ther. 16:5 (2010), e138–e156.
24. Wrayzx, S., Jones, K., Kupittayanant, S., Li, Y., Matthew, A., Monir-Bishty, E., Shmygol, A.V., Calcium signaling and uterine contractility. J. Soc. Gynecol. Investig. 10:5 (2003), 252–264.
25. Wrobel, M.H., Grzeszczyk, M., Mlynarczuk, J., Kotwica, J., The adverse effects of aldrin and dieldrin on both myometrial contractions and the secretory functions of bovine ovaries and uterus in vitro. Toxicol. Appl. Pharmacol. 285:1 (2015), 23–31.
26. Zahradnik, H.P., Hanjalic-Beck, A., Groth, K., Nonsteroidal anti-inflammatory drugs and hormonal contraceptives for pain relief from dysmenorrhea: a review. Contraception 81:3 (2010), 185–196.
27. Zingg, H.H., Laporte, S.A., The oxytocin receptor. Trends Endocrinol. Metab. 14:5 (2003), 222–227.
28. Zhang, J., Li, L., Kim, S.H., Hagerman, A.E., Lü, J., Anti-Cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose. Pharm. Res. 26:9 (2009), 2066–2080.
29. Zhang, G.H., Clinical observation of Guizhi Fuling capsule treating endometriosis. J. Liaoning Univ. Tradit. Chin. Med. 14:4 (2012), 188–189.