Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways

BMC complementary and alternative medicine

Volumn 16, Issue , 2016, Pages 58-

  Zhang, Chao ^a   Jia, Xuejing ^a   Bao, Jiaolin ^a   Chen, Shenghui ^a   Wang, Kai ^a   Zhang, Yulin ^a   Li, Peng ^a   Wan, Jian Bo ^a   Su, Huanxing ^a   Wang, Yitao ^a   Mei, Zhinan ^a   He, Chengwei ^a  

^a SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HERBACEOUS AGENT; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYPHYLLIN VII; PROTEIN P53; PTEN PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; SAPONIN;

APOPTOSIS; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HEP-G2 CELL LINE; HUMAN; LILIACEAE; METABOLISM; MITOCHONDRION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; HEP G2 CELLS; HUMANS; LILIACEAE; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; PTEN PHOSPHOHYDROLASE; REACTIVE OXYGEN SPECIES; SAPONINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84976589112     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1036-x     Document Type: Article

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