Gender Disparities in Access to Pediatric Renal Transplantation in Europe: Data From the ESPN/ERA-EDTA Registry

American Journal of Transplantation

Volumn 16, Issue 7, 2016, Pages 2097-2105

  Hogan, J ^a,b   Couchoud, C ^a   Bonthuis, M ^c   Groothoff, J W ^d   Jager, K J ^c   Schaefer, F ^e   Van Stralen, K J ^c   Shitza, D ^f   Kramar, R ^f   Oberbauer, R ^f   Baiko, S ^f   Sukalo, A ^f   van Hoeck, K ^f   Collart, F ^f   des Grottes, J M ^f   Pokrajac, D ^f   Resic H ^f   Prnjavorac, B ^f   Roussinov, D ^f   Batinic D ^f   Lemac, M ^f   Slavicek, J ^f   Seeman, T ^f   Vondrak, K ^f   Heaf, J G ^f   Toots, U ^f   Finne, P ^f   Gronhagen Riska C ^f   Lasalle, M ^f   Sahpazova, E ^f   Gersdorf, G ^f   Barth, C ^f   Scholz, C ^f   Tonshoff B ^f   Ioannidis, G ^f   Kapogiannis, A ^f   Papachristou, F ^f   Reusz, G ^f   Turi S ^f   Szabo L ^f   Szabo T ^f   Gyorke Z S ^f   Kis, E ^f   Palsson, R ^f   Edvardsson, V ^f   Gianoglio, B ^f   de Palo, T ^f   Pecoraro, C ^f   Picca, S ^f   Testa, S ^f   Vidal, E ^f   Mencarelli, F ^f   Jankauskiene, A ^f   Pundziene, B ^f   Said Conti, V ^f   Gatcan, S ^f   Berbeca, O ^f   Zaikova, N ^f   Pavicevic S ^f   Leivestad, T ^f   Bjerre, A ^f   Zurowska, A ^f   Zagozdzon, I ^f   Mota, C ^f   Almeida, M ^f   Afonso, C ^f   Mircescu, G ^f   Garneata, L ^f   Podgoreanu, E ^f   Molchanova, E A ^f   Tomilina, N A ^f   Bikbov, B T ^f   Kostic, M ^f   Peco Antic, A ^f   Puric, S ^f   Kruscic, D ^f   Spasojevic Dimitrijeva, B ^f   Milosecski Lomic, G ^f   Paripovic, D ^f   Podracka, L ^f   Kolvek, G ^f   Buturovic Ponikvar, J ^f   Novljan, G ^f   Battelino, N ^f   Alonso Melgar, A ^f   Schon S ^f   Prutz K G ^f   Seeberger, A ^f   Backman L ^f   Evans, M ^f   Kuenhi, C E ^f   Maurer, E ^f   Laube, G ^f   Simometi, G ^f   Hoitsma, A ^f   Hemke, A ^f   Topaloglu, R ^f   Duzova, A ^f   Ivanov, D ^f   Sinha, M ^f   more..

^a AGENCE DE LA BIOMÉDECINE   (France)

^b HÔPITAL ROBERT DEBRÉ   (France)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d EMMA CHILDREN S HOSPITAL   (Netherlands)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f NONE

Author keywords

clinical research practice; ethics and public policy; kidney transplantation nephrology; organ allocation; organ procurement and allocation; pediatrics; recipient selection; registry registry analysis

Indexed keywords

ADOLESCENT; ARTICLE; CHILD; COHORT ANALYSIS; END STAGE RENAL DISEASE; EUROPE; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEALTH BEHAVIOR; HEALTH CARE ACCESS; HEALTH CARE DISPARITY; HUMAN; INCIDENCE; INFANT; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; LOGISTIC REGRESSION ANALYSIS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NEWBORN; ORGAN DONOR; PARENT; PEDIATRIC SURGERY; PHYSICIAN ATTITUDE; PREEMPTIVE TRANSPLANTATION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; SCHOOL CHILD; SEX DIFFERENCE; VALIDATION STUDY;

EID: 84976464990     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.13723     Document Type: Article

References (27)

1. Evans RW, Manninen DL, Garrison LP Jr, et al. The quality of life of patients with end-stage renal disease. N Engl J Med 1985; 312: 553–559.
2. Port FK, Wolfe RA, Mauger EA, Berling DP, Jiang K. Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients. JAMA 1993; 270: 1339–1343.
3. Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341: 1725–1730.
4. Garcia GG, Harden P, Chapman J. The global role of kidney transplantation. Lancet 2012; 379: e36–e38.
5. Wong G, Howard K, Chapman JR, et al. Comparative survival and economic benefits of deceased donor kidney transplantation and dialysis in people with varying ages and co-morbidities. PLoS ONE 2012; 7: e29591.
6. Gillen DL, Stehman-Breen CO, Smith JM, et al. Survival advantage of pediatric recipients of a first kidney transplant among children awaiting kidney transplantation. Am J Transplant 2008; 8: 2600–2606.
7. Harambat J, Macher MA, Niaudet P, Couchoud C. Children and adolescents with ESRD. Nephrol Ther 2012; 8(Suppl 1): S149–S159.
8. Couchoud C, Bayat S, Villar E, Jacquelinet C, Ecochard R. A new approach for measuring gender disparity in access to renal transplantation waiting lists. Transplantation 2012; 94: 513–519.
9. Oniscu GC, Schalkwijk AA, Johnson RJ, Brown H, Forsythe JL. Equity of access to renal transplant waiting list and renal transplantation in Scotland: Cohort study. BMJ 2003; 327: 1261.
10. Ravanan R, Udayaraj U, Ansell D, et al. Variation between centres in access to renal transplantation in UK: Longitudinal cohort study. BMJ 2010; 341: c3451.
11. Segev DL, Kucirka LM, Oberai PC, et al. Age and comorbidities are effect modifiers of gender disparities in renal transplantation. J Am Soc Nephrol 2009; 20: 621–628.
12. Alexander GC, Sehgal AR. Barriers to cadaveric renal transplantation among blacks, women, and the poor. JAMA 1998; 280: 1148–1152.
13. McCauley J, Irish W, Thompson L, et al. Factors determining the rate of referral, transplantation, and survival on dialysis in women with ESRD. Am J Kidney Dis 1997; 30: 739–748.
14. Nguyen S, Martz K, Stablein D, Neu A. Wait list status of pediatric dialysis patients in North America. Pediatr Transplant 2011; 15: 376–383.
15. Tizard EJ, Verrina E, van Stralen KJ, Jager KJ. Progress with the European Society for Pediatric Nephrology (ESPN)/ERA-EDTA Registry for children with established renal failure (ERF). Nephrol Dial Transplant 2009; 24: 2615–2617.
16. Harambat J, van Stralen KJ, Schaefer F, et al. Disparities in policies, practices and rates of pediatric kidney transplantation in Europe. Am J Transplant 2013; 13: 2066–2074.
17. Furth SL, Garg PP, Neu AM, Hwang W, Fivush BA, Powe NR. Racial differences in access to the kidney transplant waiting list for children and adolescents with end-stage renal disease. Pediatrics 2000; 106: 756–761.
18. Garg PP, Furth SL, Fivush BA, Powe NR. Impact of gender on access to the renal transplant waiting list for pediatric and adult patients. J Am Soc Nephrol 2000; 11: 958–964.
19. NAPRTCS. NAPRTCS annual transplant report. 2010. Available from: https://web.emmes.com/study/ped/annlrept/2010_Report.pdf.
20. Silbiger SR, Neugarten J. The impact of gender on the progression of chronic renal disease. Am J Kidney Dis 1995; 25: 515–533.
21. Silbiger S, Neugarten J. Gender and human chronic renal disease. Gend Med 2008: 5(Suppl A): S3–S10.
22. Bloembergen WE, Port FK, Mauger EA, Briggs JP, Leichtman AB. Gender discrepancies in living related renal transplant donors and recipients. J Am Soc Nephrol 1996; 7: 1139–1144.
23. Thamer M, Hwang W, Fink NE, et al. U.S. nephrologists' attitudes towards renal transplantation: Results from a national survey. Transplantation 2001; 71: 281–288.
24. Chisholm MA, Kwong WJ, Spivey CA. Associations of characteristics of renal transplant recipients with clinicians' perceptions of adherence to immunosuppressant therapy. Transplantation 2007; 84: 1145–1150.
25. Van Arendonk KJ, James NT, Boyarsky BJ, et al. Age at graft loss after pediatric kidney transplantation: Exploring the high-risk age window. Clin J Am Soc Nephrol 2013; 8: 1019–1026.
26. Hogan J, Savoye E, Macher MA, et al. Rapid access to renal transplant waiting list in children: Impact of patient and centre characteristics in France. Nephrol Dial Transplant 2014; 29: 1973–1979.
27. Hogan J, Audry B, Harambat J, et al. Are there good reasons for inequalities in access to renal transplantation in children? Nephrol Dial Transplant 2015; 30: 2080–2087.