De novo assembly of human herpes virus type 1 (HHV-1) genome, mining of non-canonical structures and detection of novel drug-resistance mutations using short- and long-read next generation sequencing technologies

PLoS ONE

Volumn 11, Issue 6, 2016, Pages

  Karamitros, Timokratis ^a,b   Harrison, Ian ^a,b   Piorkowska, Renata ^a,b   Katzourakis, Aris ^a,b   Magiorkinis, Gkikas ^a,b   Mbisa, Jean Lutamyo ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; CIDOFOVIR; FOSCARNET; PENCICLOVIR; VIRUS DNA;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIVIRAL RESISTANCE; ANTIVIRAL THERAPY; ARTICLE; BIOINFORMATICS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE IDENTIFICATION; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; GENE STRUCTURE; GENETIC VARIABILITY; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; IMMUNOCOMPROMISED PATIENT; MOLECULAR EVOLUTION; NEXT GENERATION SEQUENCING; NONHUMAN; UL23 GENE; VIRUS ASSEMBLY; VIRUS GENE; VIRUS GENOME; VIRUS ISOLATION; VIRUS MUTATION; VIRUS PATHOGENESIS; VIRUS VIRULENCE; ANIMAL; CHLOROCEBUS AETHIOPS; CLASSIFICATION; CONTIG MAPPING; DNA BASE COMPOSITION; DRUG EFFECTS; GENETICS; GENOME SIZE; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; MUTATION; VERO CELL LINE; VIROLOGY;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIVIRAL AGENTS; BASE COMPOSITION; CERCOPITHECUS AETHIOPS; CONTIG MAPPING; DNA, VIRAL; DRUG RESISTANCE, VIRAL; GENOME SIZE; GENOME, VIRAL; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; IMMUNOCOMPROMISED HOST; MUTATION; VERO CELLS;

EID: 84976407192     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0157600     Document Type: Article

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