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Volumn 15, Issue 3, 2016, Pages 311-316

Anti-IL-17 agents for psoriasis: A review of phase III data

Author keywords

[No Author keywords available]

Indexed keywords

BRODALUMAB; IXEKIZUMAB; SECUKINUMAB; IL17A PROTEIN, HUMAN; INTERLEUKIN 17; MONOCLONAL ANTIBODY;

EID: 84975882393     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (38)

References (31)
  • 2
    • 84879492055 scopus 로고    scopus 로고
    • Cytokine-based therapy in psoriasis
    • Mitra A, Fallen RS, Lima HC. Cytokine-based therapy in psoriasis. Clin Rev Allergy Immunol. 2013;44(2):173–82. doi:10.1007/s12016-012-8306-2.
    • (2013) Clin Rev Allergy Immunol , vol.44 , Issue.2 , pp. 173-182
    • Mitra, A.1    Fallen, R.S.2    Lima, H.C.3
  • 3
    • 84879503193 scopus 로고    scopus 로고
    • Role of IL-17 in psoriasis and psoriatic arthritis
    • Raychaudhuri SP. Role of IL-17 in psoriasis and psoriatic arthritis. Clin Rev Allergy Immunol. 2013;44(2):183–93. doi:10.1007/s12016-012-8307-1.
    • (2013) Clin Rev Allergy Immunol , vol.44 , Issue.2 , pp. 183-193
    • Raychaudhuri, S.P.1
  • 4
    • 33751546237 scopus 로고    scopus 로고
    • IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
    • Chan JR, Blumenschein W, Murphy E, et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med. 2006;203(12):2577–87. doi:10.1084/jem.20060244.
    • (2006) J Exp Med , vol.203 , Issue.12 , pp. 2577-2587
    • Chan, J.R.1    Blumenschein, W.2    Murphy, E.3
  • 5
    • 84862909259 scopus 로고    scopus 로고
    • Interleukin-23: As a drug target for autoimmune inflammatory diseases
    • Tang C, Chen S, Qian H, Huang W. Interleukin-23: as a drug target for autoimmune inflammatory diseases. Immunology. 2012;135(2):112–24. doi:10.1111/j.1365-2567.2011.03522.x.
    • (2012) Immunology , vol.135 , Issue.2 , pp. 112-124
    • Tang, C.1    Chen, S.2    Qian, H.3    Huang, W.4
  • 6
    • 0033557728 scopus 로고    scopus 로고
    • Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
    • Laan M, Cui ZH, Hoshino H, et al. Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol. 1999;162(4):2347–52. Available at: http://www.jimmunol.org/cgi/pmidlookup?view=long&pmid9973514.
    • (1999) J Immunol , vol.162 , Issue.4 , pp. 2347-2352
    • Laan, M.1    Cui, Z.H.2    Hoshino, H.3
  • 7
    • 0037849915 scopus 로고    scopus 로고
    • Interleukin-17 promotes angiogenesis and tumor growth
    • Numasaki M, Fukushi J, Ono M, et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood. 2003;101(7):2620–7. doi:10.1182/blood-2002-05-1461.
    • (2003) Blood , vol.101 , Issue.7 , pp. 2620-2627
    • Numasaki, M.1    Fukushi, J.2    Ono, M.3
  • 8
    • 84864740281 scopus 로고    scopus 로고
    • Serum and tissue levels of IL-17 in different clinical subtypes of psoriasis
    • Yilmaz SB, Cicek N, Coskun M, Yegin O, Alpsoy E. Serum and tissue levels of IL-17 in different clinical subtypes of psoriasis. Arch Dermatol Res. 2012;304(6):465–9. doi:10.1007/s00403-012-1229-1.
    • (2012) Arch Dermatol Res , vol.304 , Issue.6 , pp. 465-469
    • Yilmaz, S.B.1    Cicek, N.2    Coskun, M.3    Yegin, O.4    Alpsoy, E.5
  • 9
    • 84924331397 scopus 로고    scopus 로고
    • Anti-IL-17 phase II data for psoriasis: A review
    • Brown G, Malakouti M, Wang E, Koo J, Levin E. Anti-IL-17 phase II data for psoriasis: A review. J Dermatolog Treat. 2014;26(1):32–6. doi:10.3109/09546634.2013.878448.
    • (2014) J Dermatolog Treat , vol.26 , Issue.1 , pp. 32-36
    • Brown, G.1    Malakouti, M.2    Wang, E.3    Koo, J.4    Levin, E.5
  • 10
    • 84899083985 scopus 로고    scopus 로고
    • Patient perspectives in the management of psoriasis: Results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey
    • Lebwohl MG, Bachelez H, Barker J, et al. Patient perspectives in the management of psoriasis: results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey. J Am Acad Dermatol. 2014;70(5):871–81.e1–30. doi:10.1016/j.jaad.2013.12.018.
    • (2014) J Am Acad Dermatol , vol.70 , Issue.5
    • Lebwohl, M.G.1    Bachelez, H.2    Barker, J.3
  • 11
    • 84906278947 scopus 로고    scopus 로고
    • Social impact of the burden of psoriasis: Effects on patients and practice
    • Feldman SR, Malakouti M, Koo JY. Social impact of the burden of psoriasis: effects on patients and practice. Dermatol Online J. 2014;20(8).
    • (2014) Dermatol Online J , vol.20 , Issue.8
    • Feldman, S.R.1    Malakouti, M.2    Koo, J.Y.3
  • 12
    • 85029096629 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals ClinicalTrials gov [Internet] Bethesda MD National Library of Medicine US [cited 2015 April 3] Available from NLM Identifier NCT01874340
    • Novartis Pharmaceuticals. Efficacy and Safety of AIN457 (Secukinumab) in Patients With Relapsing Multiple Sclerosis. In: ClinicalTrials. gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2013 [cited 2015 April 3]. Available from: https://clinicaltrials. gov/ct2/show/NCT01874340 NLM Identifier: NCT01874340.
    • (2013) Efficacy and Safety of AIN457 (secukinumab) in Patients with Relapsing Multiple Sclerosis
  • 13
    • 85029085556 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals ClinicalTrials gov [Internet] Bethesda MD National Library of Medicine US [cited 2015 April 3] Available from NLM Identifier NCT01892436
    • Novartis Pharmaceuticals. Extension Study up to 3 Years for Secukinumab in Psoriatic Arthritis (FUTURE 1 ext). In: ClinicalTrials. gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2013 [cited 2015 April 3]. Available from: https://clinicaltrials. gov/ct2/show/NCT01892436 NLM Identifier: NCT01892436.
    • (2013) Extension Study up to 3 Years for Secukinumab in Psoriatic Arthritis (FUTURE 1 Ext)
  • 14
    • 84875697084 scopus 로고    scopus 로고
    • Secukinumab in the treatment of noninfectious uveitis: Results of three randomized, controlled clinical trials
    • Dick AD, Tugal-Tutkun I, Foster S, et al. Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials. Ophthalmology. 2013;120(4):777–87. doi:10.1016/j.ophtha.2012.09.040.
    • (2013) Ophthalmology , vol.120 , Issue.4 , pp. 777-787
    • Dick, A.D.1    Tugal-Tutkun, I.2    Foster, S.3
  • 15
    • 84904545875 scopus 로고    scopus 로고
    • Secukinumab in plaque psoriasis—results of two phase 3 trials
    • Langley R, Elewski B, Lebwohl M, et al. Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials. N Engl J Med. 2014;371(4):326–38. doi:10.1056/NEJMoa1314258.
    • (2014) N Engl J Med , vol.371 , Issue.4 , pp. 326-338
    • Langley, R.1    Elewski, B.2    Lebwohl, M.3
  • 16
    • 84922933349 scopus 로고    scopus 로고
    • Secukinumab administration by pre-filled syringe: Efficacy, safety and usability results from a randomized controlled trial in psoriasis (FEATURE)
    • Blauvelt A, Prinz JC, Gottlieb AB, et al. Secukinumab administration by pre-filled syringe: efficacy, safety and usability results from a randomized controlled trial in psoriasis (FEATURE). Br J Dermatol. 2015;172(2):484–93. doi:10.1111/bjd.13348.
    • (2015) Br J Dermatol , vol.172 , Issue.2 , pp. 484-493
    • Blauvelt, A.1    Prinz, J.C.2    Gottlieb, A.B.3
  • 17
    • 84929629144 scopus 로고    scopus 로고
    • Efficacy, safety and usability of secukinumab administration by autoinjector/pen in psoriasis: A randomized, controlled trial (JUNCTURE)
    • Paul, Lacour J -P., Tedremets, et al. Efficacy, safety and usability of secukinumab administration by autoinjector/pen in psoriasis: a randomized, controlled trial (JUNCTURE). J Eur Acad Dermatol Venereol. 2015;29(6). doi:10.1111/jdv.12751.
    • (2015) J Eur Acad Dermatol Venereol , vol.29 , Issue.6
    • Paul, L.J.-P.1    Tedremets2
  • 18
    • 84939463415 scopus 로고    scopus 로고
    • Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial
    • Thaçi D, Blauvelt A, Reich K, et al. Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate to severe plaque psoriasis: CLEAR, a randomized controlled trial. J Am Acad Dermatol. 2015;73(3):400–9. doi:10.1016/j.jaad.2015.05.013.
    • (2015) J Am Acad Dermatol , vol.73 , Issue.3 , pp. 400-409
    • Thaçi, D.1    Blauvelt, A.2    Reich, K.3
  • 20
    • 84977275873 scopus 로고    scopus 로고
    • Efficacy and safety of brodalumab in patients with moderate to severe plaque psoriasis: results of amagine-1, a phase 3, randomized, double-blind, placebo controlled study through week 12
    • March 20-24 San Francisco CA
    • Papp K, Reich K, Leonardi C, et al. Efficacy and Safety of Brodalumab In Patients With Moderate To Severe Plaque Psoriasis: Results of AMAGINE-1, a Phase 3, Randomized, Double-Blind, Placebo Controlled Study Through Week 12. Presented at the 73rd Annual Meeting of the American Academy of Dermatology; 2015 March 20-24; San Francisco, CA.
    • (2015) 73rd Annual Meeting of the American Academy of Dermatology
    • Papp, K.1    Reich, K.2    Leonardi, C.3
  • 21
    • 84942876148 scopus 로고    scopus 로고
    • Phase 3 studies comparing brodalumab with ustekinumab in psoriasis
    • Lebwohl M, Strober B, Menter A, et al. Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis. N Engl J Med. 2015;373(14). doi:10.1056/NEJMoa1503824.
    • (2015) N Engl J Med , vol.373 , Issue.14
    • Lebwohl, M.1    Strober, B.2    Menter, A.3
  • 23
    • 85013209319 scopus 로고    scopus 로고
    • Ixekizumab for treatment of moderate-to-severe plaque psoriasis: 60-week results from a double-blind phase 3 induction and randomized withdrawal study (UNCOVER-1)
    • March 20-24 San Francisco CA
    • Gordon K, et al. Ixekizumab for Treatment of Moderate-to-Severe Plaque Psoriasis: 60-Week Results From a Double-Blind Phase 3 Induction and Randomized Withdrawal Study (UNCOVER-1). Presented at the 73rd Annual Meeting of the American Academy of Dermatology; 2015 March 20-24; San Francisco, CA.
    • (2015) 73rd Annual Meeting of the American Academy of Dermatology
    • Gordon, K.1
  • 24
    • 84938992082 scopus 로고    scopus 로고
    • Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): Results from two phase 3 randomised trials
    • Griffiths C, Reich K, Lebwohl M, et al. Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials. The Lancet. 2015;386(9993). doi:10.1016/S0140-6736(15)60125-8.
    • (2015) The Lancet , vol.386 , pp. 9993
    • Griffiths, C.1    Reich, K.2    Lebwohl, M.3
  • 25
    • 40949112391 scopus 로고    scopus 로고
    • Relationship between clinical response to therapy and health-related quality of life outcomes in patients with moderate to severe plaque psoriasis
    • Revicki DA, Willian MK, Menter A, Saurat J-HH, Harnam N, Kaul M. Relationship between clinical response to therapy and health-related quality of life outcomes in patients with moderate to severe plaque psoriasis. Dermatology (Basel). 2008;216(3):260–70. doi:10.1159/000113150.
    • (2008) Dermatology (Basel) , vol.216 , Issue.3 , pp. 260-270
    • Revicki, D.A.1    Willian, M.K.2    Menter, A.3    Saurat, J.-H.H.4    Harnam, N.5    Kaul, M.6
  • 26
    • 79953284685 scopus 로고    scopus 로고
    • Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity
    • Puel A, Cypowyj S, Bustamante J, et al. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science. 2011;332(6025):65–8. doi:10.1126/science.1200439.
    • (2011) Science , vol.332 , Issue.6025 , pp. 65-68
    • Puel, A.1    Cypowyj, S.2    Bustamante, J.3
  • 27
    • 84942891597 scopus 로고    scopus 로고
    • Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis
    • Mease PJ, McInnes IB, Kirkham B, et al. Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis. N Engl J Med. 2015;373(14):1329–39. doi:10.1056/NEJMoa1412679.
    • (2015) N Engl J Med , vol.373 , Issue.14 , pp. 1329-1339
    • Mease, P.J.1    McInnes, I.B.2    Kirkham, B.3
  • 28
    • 84869831363 scopus 로고    scopus 로고
    • Association between tumor necrosis factor inhibitor therapy and myocardial infarction risk in patients with psoriasis
    • Wu JJ, Poon K-YTY, Channual JC, Shen AY. Association between tumor necrosis factor inhibitor therapy and myocardial infarction risk in patients with psoriasis. Arch Dermatol. 2012;148(11):1244–50. doi:10.1001/archdermatol.2012.2502.
    • (2012) Arch Dermatol , vol.148 , Issue.11 , pp. 1244-1250
    • Wu, J.J.1    Poon, K.-Y.T.Y.2    Channual, J.C.3    Shen, A.Y.4
  • 29
    • 76749088486 scopus 로고    scopus 로고
    • Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques
    • De Boer OJ, van der Meer JJ, Teeling P, et al. Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques. J Pathol. 2010;220(4):499–508. doi:10.1002/path.2667.
    • (2010) J Pathol , vol.220 , Issue.4 , pp. 499-508
    • De Boer, O.J.1    Van Der Meer, J.J.2    Teeling, P.3
  • 30
    • 8444250164 scopus 로고    scopus 로고
    • Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease
    • Csiszar A, Ungvari Z. Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease. Med Hypotheses. 2004;63(4):696–8. doi:10.1016/j.mehy.2004.03.009.
    • (2004) Med Hypotheses , vol.63 , Issue.4 , pp. 696-698
    • Csiszar, A.1    Ungvari, Z.2
  • 31
    • 33845585620 scopus 로고    scopus 로고
    • Role of interleukin-17 and interleukin-17-induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease
    • Hashmi S, Zeng QT. Role of interleukin-17 and interleukin-17-induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease. Coron Artery Dis. 2006;17(8):699–706. doi:10.1097/01.mca.0000236288.94553.b4.
    • (2006) Coron Artery Dis , vol.17 , Issue.8 , pp. 699-706
    • Hashmi, S.1    Zeng, Q.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.