Short-Term Efficacy Reliably Predicts Long-Term Clinical Benefit in Rheumatoid Arthritis Clinical Trials as Demonstrated by Model-Based Meta-Analysis

Journal of Clinical Pharmacology

Volumn , Issue , 2016, Pages 835-844

  Wang, Yehong ^a   Zhu, Rui ^a   Xiao, Jim ^a   Davis, John C ^a   Mandema, Jaap W ^b   Jin, Jin Y ^a   Tang, Meina T ^a,c  

^a GENENTECH INC   (United States)

^b Quantitative Solutions   (United States)

^c American College of Clinical Pharmacology   (United States)

Author keywords

ACR50; efficacy; meta analysis; rheumatoid arthritis

Indexed keywords

ABATACEPT; ADALIMUMAB; CERTOLIZUMAB PEGOL; ETANERCEPT; FOSTAMATINIB; GOLIMUMAB; OCRELIZUMAB; OFATUMUMAB; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RITUXIMAB; TOCILIZUMAB; TOFACITINIB;

ACR50; ARTICLE; CONTROLLED CLINICAL TRIAL (TOPIC); DAS28; FEASIBILITY STUDY; HUMAN; META ANALYSIS; NONLINEAR SYSTEM; PREDICTIVE VALUE; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RELIABILITY; RHEUMATOID ARTHRITIS; SCORING SYSTEM;

EID: 84974688229     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.668     Document Type: Article

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