Fluorescent probes and nanoparticles for intracellular sensing of pH values

Methods and Applications in Fluorescence

Volumn 2, Issue 4, 2014, Pages

  Shi, Wen ^a   Li, Xiaohua ^a   Ma, Huimin ^a  

^a INSTITUTE OF CHEMISTRY   (China)

Author keywords

Fluorescent pH nanoprobes; Fluorescent pH probes; Intracellular pH detection

Indexed keywords

EID: 84974623732     PISSN: None     EISSN: 20506120     Source Type: Journal    
DOI: 10.1088/2050-6120/2/4/042001     Document Type: Article

References (69)

1. Albertazzi L, Storti B, Marchetti L and Beltram F 2010 Delivery and subcellular targeting of dendrimer-based fluorescent pH sensors in living cells J. Am. Chem. Soc. 132 18158-67
2. Benjaminsen R V, Sun H H, Henriksen J R, Christensen N M, Almdal K and Andresen T L 2011 Evaluating nanoparticle sensor design for intracellular pH measurements ACS Nano 5 5864-73
3. Chen L Z, Li J, Liu Z Z, Ma Z, Zhang W, Du L P, Xu W F, Fang H and Li M Y 2013a A novel pH 'off-on' fluorescent probe for lysosome imaging RSC Adv. 3 13412-6
4. Chen S et al 2012a An AIE-active hemicyanine fluorogen with stimuli-responsive red/blue emission: extending the pH sensing range by 'switch + knob' effect Chem. Sci. 3 1804-9
5. Chen S et al 2013b Full-range intracellular pH sensing by an aggregation-induced emission-active two-channel ratiometric fluorogen J. Am. Chem. Soc. 135 4926-9
6. Chen Y P, Chen H A, Hung Y, Chien F C, Chen P and Mou C Y 2012b Surface charge effect in intracellular localization of mesoporous silica nanoparticles as probed by fluorescent ratiometric pH imaging RSC Adv. 2 968-73
7. Cody S H, Dubbin P N, Beischer A D, Duncan N D, Hill J S, Kaye A H and Williams D A 1993 Intracellular pH mapping with SNARF-1 and confocal microscopy: I. A quantitative technique for living tissues and isolated cells Micron 24 573-80
8. Dennis A M, Rhee W J, Sotto D, Dublin S N and Bao G 2012 Quantum dot fluorescent protein FRET probes for sensing intracellular pH ACS Nano 6 2917-24
9. Fan L, Fu Y J, Liu Q L, Lu D T, Dong C and Shuang S M 2012 Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells Chem. Commun. 48 11202-4
10. Fan L, Liu Q L, Lu D T, Shi H P, Yang Y F, Li Y F, Dong C and Shuang S M 2013 A novel far-visible and near-infrared pH probe for monitoring near-neutral physiological pH changes: imaging in live cells J. Mater. Chem. B 1 4281-8
11. Guo J H, Xiong S J, Wu X L, Shen J C and Chu P K 2013 In situ probing of intracellular pH by fluorescence from inorganic nanoparticles Biomaterials 34 9183-9
12. Han F F, Xu Y M, Jiang D C, Qin Y and Chen H Y 2013 A BODIPY-derived fluorescent probe for cellular pH measurements Anal. Biochem. 435 106-13
13. Han J and Burgess K 2010 Fluorescent indicators for intracellular pH Chem. Rev. 110 2709-28
14. Han J, Loudet A, Barhoumi R, Burghardt R C and Burgess K 2009 A ratiometric pH reporter for imaging protein-dye conjugates in living cells J. Am. Chem. Soc. 131 1642-3
15. Hu J L, Wu F, Feng S, Xu J H, Xu Z H, Chen Y Q, Tang T, Weng X C and Zhou X 2014 A convenient ratiomeric pH probe and its application for monitoring pH change in living cells Sensors Actuators B 196 194-202
16. Huang W M, Lin W Y and Guan X Y 2014 Development of ratiometric fluorescent pH sensors based on chromenoquinoline derivatives with tunable pKa values for bioimaging Tetrahedron Lett. 55 116-9
17. Janata J 1987 Do optical sensors really measure pH Anal. Chem. 59 1351-6
18. Kim H J, Heo C H and Kim H M 2013 Benzimidazole-based ratiometric two-photon fluorescent probes for acidic pH in live cells and tissues J. Am. Chem. Soc. 135 17969-77
19. Kong B, Zhu A W, Ding C Q, Zhao X M, Li B and Tian Y 2012 Carbon dot-based inorganic-organic nanosystem for twophoton imaging and biosensing of pH variation in living cells and tissues Adv. Mater. 24 5844-8
20. Lee M H, Gubernator N G, Sulzer D and Sames D 2010 Development of pH-responsive fluorescent false neurotransmitters J. Am. Chem. Soc. 132 8828-30
21. Lee M H, Han J H, Lee J H, Park N, Kumar R, Kang C and Kim J S 2013 Two-color probe to monitor a wide range of pH values in cells Angew. Chem. Int. Ed. 52 6206-9
22. Li G P, Zhu D J, Xue L and Jiang H 2013a Quinoline-based fluorescent probe for ratiometric detection of lysosomal pH Org. Lett. 15 5020-3
23. Li L H, Li Z, Shi W, Li X H and Ma H M 2014a Sensitive and selective near-infrared fluorescent off - on probe and its application to imaging different levels of β-lactamase in Staphylococcus aureus Anal. Chem. 86 6115-20
24. Li P, Xiao H B, Cheng Y F, Zhang W, Huang F, Zhang W, Wang H and Tang B 2014b A near-infrared-emitting fluorescent probe for monitoring mitochondrial pH Chem. Commun. 50 7184-7
25. Li X H, Gao X H, Shi W and Ma H M 2014c Design strategies for water-soluble small molecular chromogenic and fluorogenic probes Chem. Rev. 114 590-659
26. Li Z, Wu S Q, Han J H, Yang L and Han S F 2011 Imaging of intracellular acidic compartments with a sensitive rhodamine based fluorogenic pH sensor Analyst 136 3698-706
27. Li Z, Wu S Q, Han J H, Yang L and Han S F 2013b Resolution of lysosomes in living cells with a ratiometric molecular pH-meter Talanta 114 254-60
28. Liopis J, McCaffery J M, Miyawaki A, Farquhar M G and Tsein R Y 1998 Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins Proc. Natl Acad. Sci. USA 95 6803-8
29. Liu M J, Ye Z Q, Xin C L and Yuan J L 2013 Development of a ratiometric time-resolved luminescence sensor for pH based on lanthanide complexes Anal. Chim. Acta 761 149-56
30. Liu Y S, Sun Y H, Vernier P T, Liang C H, Chong S Y C and Gundersen M A 2007 pH-Sensitive photoluminescence of CdSe/ZnSe/ZnS quantum dots in human ovarian cancer cells J. Phys. Chem. C 111 2872-8
31. Ma X P, Wang Y G, Zhao T, Li Y, Su L C, Wang Z H, Huang G, Sumer B D and Gao J M 2014 Ultra-pH-sensitive nanoprobe library with broad pH tunability and fluorescence emissions J. Am. Chem. Soc. 136 11085-92
32. Marín M, Galindo F, Thomas P and Russell D A 2012 Localized intracellular pH measurement using a ratiometric photoinduced electron-transfer-based nanosensor Angew. Chem. Int. Ed. 51 9657-61
33. Mathew N D, Mathew M D and Surawski P P T 2014 Nanoparticle imaging and diagnostic of Caenorhabditis elegans intracellular pH Anal. Biochem. 450 52-6
34. Medintz I L, Stewart M H, Trammell S A, Susumu K, Delehanty J B, Mei B C, Melinger J S, Blanco-Canosa J B, Dawson P E and Mattoussi H 2010 Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing Nat. Mater. 9 676-84
35. Miao F, Song G F, Sun Y M, Liu Y, Guo F Q, Zhang W J, Tian M G and Yu X Q 2013 Fluorescent imaging of acidic compartments in living cells with a high selective novel onephoton ratiometric and two-photon acidic pH probe Biosens. Bioelectron. 50 42-9
36. Myochin T, Kiyose K, Hanaoka K, Kojima H, Terai T and Nagano T 2011 Rational design of ratiometric near-infrared fluorescent pH probes with various pKa values, based on aminocyanine J. Am. Chem. Soc. 133 3401-9
37. Nie H, Li M J, Li Q S, Liang S J, Tan Y Y, Sheng L, Shi W and Zhang S X 2014 Carbon dots with continuously tunable fullcolor emission and their application in ratiometric pH sensing Chem. Mater. 26 3104-12
38. Orte A, Alvarez-Pez J M and Ruedas-Rama M J 2013 Fluorescence lifetime imaging microscopy for the detection of intracellular pH with quantum dot nanosensors ACS Nano 7 6387-95
39. Park H J, Lim C S, Kim E S, Han J H, Lee T H, Chun H J and Cho B R 2012 Measurement of pH values in human tissues by two-photon microscopy Angew. Chem. Int. Ed. 51 2673-6
40. Peng H S, Stolwijk J A, Sun L N, Wegener J and Wolfbeis O S 2010 A nanogel for ratiometric fluorescent sensing of intracellular pH values Angew. Chem. Int. Ed. 49 4246-9
41. Qu S N, Chen H, Zheng X M, Cao J S and Liu X Y 2013 Ratiometric fluorescent nanosensor based on water soluble carbon nanodots with multiple sensing capacities Nanoscale 5 5514-8
42. Ruedas-Rama M J, Orte A, Hall E A H, Alvarez-Peza J M and Talavera E M 2011 Quantum dot photoluminescence lifetimebased pH nanosensor Chem. Commun. 47 2898-900
43. Schreml S, Meier R J, Wolfbeis O S, Landthaler M, Szeimies R M and Babilas P 2011 2D luminescence imaging of pH in vivo Proc. Natl Acad. Sci. USA 108 2432-7
44. Shi W, Li X H and Ma H M 2012 A tunable ratiometric pH sensor based on carbon nanodots and its application to quantitatively measuring the intracellular pH of whole cells Angew. Chem. Int. Ed. 51 6432-5
45. Somers R C, Lanning R M, Snee P T, Greytak A B, Jain R K, Bawendi M G and Nocera D G 2012 A nanocrystal-based ratiometric pH sensor for natural pH ranges Chem. Sci. 3 2980-5
46. Song P S, Chen X T, Xiang Y, Huang L, Zhou Z J, Wei R R and Tong A J 2011 A ratiometric fluorescent pH probe based on aggregation-induced emission enhancement and its application in live-cell imaging J. Mater. Chem. 21 13470-5
47. Song Y C, Liu J X, Zhang Y Y, Shi W and Ma H M 2013 Some problems of nanomaterials in bioanalytical applications Acta Chim. Sin. 71 1607-10
48. Srivastava J, Barber D L and Jacobson M P 2007 Intracellular pH sensors: design principles and functional significance Physiology 22 30-9
49. Su M H, Liu Y, Ma H M, Ma Q L, Wang Z H, Yang J L and Wang M X 2001 1,9-Dihydro-3-phenyl-4H-pyrazolo[3,4-b] quinolin-4-one, a novel fluorescent probe for extreme pH measurement Chem. Commun. 960-1
50. Sun H H, Almdal K and Andresen T L 2011 Expanding the dynamic measurement range for polymeric nanoparticle pH sensors Chem. Commun. 47 5268-70
51. Tang B, Yu F B, Li P, Tong L L, Duan X, Xie T and Wang X 2009 A near-infrared neutral pH fluorescent probe for monitoring minor pH changes: imaging in living HepG2 and HL-7702 cells J. Am. Chem. Soc. 131 3016-23
52. Tang R, Lee H and Achilefu S 2012 Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes J. Am. Chem. Soc. 134 4545-8
53. Tsou C J, Chu C Y, Hung Y and Mou C Y 2013 A broad range fluorescent pH sensor based on hollow mesoporous silica nanoparticles, utilising the surface curvature effect J. Mater. Chem. B 1 5557-63
54. Tian Y Q, Su F Y, Weber W, Nandakumar V, Shumway B R, Jin Y G, Zhou X F, Holl M R, Johnson R H and Meldrum D R 2010 A series of naphthalimide derivatives as intra and extracellular pH sensors Biomaterials 31 7411-22
55. Tsien R Y 1981 A non-disruptive technique for loading calcium buffers and indicators into cells Nature 290 527-8
56. Venn A A, Tambutté E, Lotto S, Zoccola D, Allemand D and Tambutté S 2009 Imaging intracellular pH in a reef coral and symbiotic anemone Proc. Natl Acad. Sci. USA 106 16574-9
57. Wan Q Q, Chen S M, Shi W, Li L H and Ma H M 2014 Lysosomal pH rise during heat shock monitored by a new lysosometargeting near-infrared ratiometric fluorescent probe Angew. Chem. Int. Ed. 53 10916-20
58. Wang K and Ma H M 2010 Biologically environment-sensitive fluorescent probes Prog. Chem. 22 1633-40
59. Wang X D, Meier R J and Wolfbeis O S 2012a A fluorophoredoped polymer nanomaterial for referenced imaging of pH and temperature with sub-micrometer resolution Adv. Funct. Mater. 22 4202-7
60. Wang X D, Meier R J and Wolfbeis O S 2013 Fluorescent pH-sensitive nanoparticles in an agarose matrix for imaging of bacterial growth and metabolism Angew. Chem. Int. Ed. 52 406-9
61. Wang X D, Stolwijk J A, Lang T, Sperber M, Meier R J, Wegener J and Wolfbeis O S 2012b Ultra-small, highly stable, and sensitive dual nanosensors for imaging intracellular oxygen and pH in cytosol J. Am. Chem. Soc. 134 17011-4
62. Wencel D, Abel T and McDonagh C 2014 Optical chemical pH sensors Anal. Chem. 86 15-29
63. Wu S Q, Li Z, Han J H and Han S F 2011 Dual colored mesoporous silica nanoparticles with pH activable rhodamine-lactam for ratiometric sensing of lysosomal acidity Chem. Commun. 47 11276-8
64. Yuan L, Lin W Y, Cao Z M, Wang J L and Chen B 2012 Development of FRET-based dual-excitation ratiometric fluorescent pH probes and their photocaged derivatives Chem. Eur. J. 18 1247-55
65. Zeng L T, Fan N, Zha J Y, Hu X C, Fu B Q, Qin C Q and Wang L 2013 A novel and photostable pH probe for selectively staining nuclei in living cells Analyst 138 7083-6
66. Zhou J, Fang C L, Chang T J, Liu X J and Shangguan D H 2013 A pH sensitive ratiometric fluorophore and its application for monitoring the intracellular and extracellular pHs simultaneously J. Mater. Chem. B 1 661-7
67. Zhou K J, Liu H M, Zhang S R, Huang X N, Wang Y G, Huang G, Sumer B D and Gao J M 2012a Multicolored pH-tunable and activatable fluorescence nanoplatform responsive to physiologic pH stimuli J. Am. Chem. Soc. 134 7803-11
68. Zhou K J, Wang Y G, Huang X N, Luby-Phelps K, Sumer B D and Gao J M 2011 Tunable, ultrasensitive pH-responsive nanoparticles targeting specific endocytic organelles in living cells Angew. Chem. Int. Ed. 50 6109-14
69. Zhou X F, Su F Y, Lu H G, Senechal-Willis P, Tian Y Q, Johnson R H and Meldrum D R 2012b An FRET-based ratiometric chemosensor for in vitro cellular fluorescence analyses of pH Biomaterials 33 171-80