Evaluation of dissolution hydrodynamics in the USP, Peak™ and flat-bottom vessels using different solubility drugs

Dissolution Technologies

Volumn 12, Issue 1, 2005, Pages 11-16

  Mirza, Tahseen ^a   Joshi, Yatindra ^a   Liu, Qian Julie ^a   Vivilecchia, Richard ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

POLYSORBATE 80; PREDNISONE;

ANALYTICAL EQUIPMENT; ARTICLE; ARTIFACT; CALIBRATOR; DISSOLUTION; DISSOLUTION APPARATUS; DISSOLUTION RATE CONSTANT; DISSOLUTION TESTING; DRUG RELEASE; DRUG SOLUBILITY; FLAT BOTTOM DISSOLUTION VESSEL; HYDRODYNAMICS; PADDLE APPARATUS; TABLET DISINTEGRATION; TABLET FORMULATION; ULTRAVIOLET SPECTROPHOTOMETRY; USP VESSEL;

EID: 84974601997     PISSN: 1521298X     EISSN: None     Source Type: Journal    
DOI: 10.14227/DT120105P11     Document Type: Article

References (7)

1. The United States Pharmacopeia, USP 28-NF23, Chapter <711>, United States Pharmacopeial Convention, Rockville, MD
2. Underwood, F. L and Cadwallader," Effect of Various Hydrodynamic Conditions on Dissolution Rate Determinations," J Pharm Sci, 65(5), 697-700, 1976.
3. Wang, T. and Coffin, D. M., AAPS Poster Number APQ1134.
4. Diebold, S., " Hydrodynamics and Dissolution," Dissolution Technologies, August 2000, 10.
5. Kukura, P. E. Arratia, E. S. Szalai, and F. J. Muzzio, "Engineering Tools for Understanding the Hydrodynamics of Dissolution Tests," Drug Dev Ind Pharm, 29(2), 231-239, 2003.
6. L. G. McCarthy, G. Bradley, J. C. Sexton, O. I. Corrigan and A. M. Healy," Computational Fluid Dynamics Modeling of the Paddle Dissolution Apparatus: Agitation Rate, Mixing Patterns, and Fluid Velocities," AAPS PharmSciTech, 5(2), Article 31, 2004.
7. Becket, A. H., Quach, T. T. and Kurs, G. S., " Improved Hydrodynamics for USP Apparatus 2," Dissolution Technologies, May 1996, 7-12.