Interventions to improve medication adherence in coronary disease patients: A systematic review and meta-analysis of randomised controlled trials

European Journal of Preventive Cardiology

Volumn 23, Issue 10, 2016, Pages 1065-1076

  Santo, Karla ^a,b,d   Kirkendall, Suzanne ^b   Laba, Tracey Lea ^a,b   Thakkar, Jay ^a,b,c   Webster, Ruth ^a,b   Chalmers, John ^a,b   Chow, Clara K ^a,b,c   Redfern, Julie ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c WESTMEAD HOSPITAL   (Australia)

^d GEORGE INSTITUTE FOR GLOBAL HEALTH   (Australia)

Author keywords

coronary disease; Medication adherence; medication compliance; meta analysis; multiple medications; polypharmacy; randomised controlled trial; systematic review

Indexed keywords

CARDIOVASCULAR AGENT;

CORONARY ARTERY DISEASE; DRUG MONITORING; HUMAN; MEDICATION COMPLIANCE; META ANALYSIS; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PATIENT COUNSELING; PATIENT EDUCATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW;

CARDIOVASCULAR AGENTS; CORONARY DISEASE; HUMANS; MEDICATION ADHERENCE; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84974593660     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487316638501     Document Type: Review

References (48)

1. Vrijens B, De Geest S, Hughes DA, et al. A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol 2012; 73: 691-705.
2. Osterberg L, Blaschke T,. Adherence to medication. N Engl J Med 2005; 353: 487-497.
3. Bowry AD, Shrank WH, Lee JL, et al. A systematic review of adherence to cardiovascular medications in resource-limited settings. J Gen Intern Med 2011; 26: 1479-1491.
4. Ho PM, Bryson CL, Rumsfeld JS,. Medication adherence: Its importance in cardiovascular outcomes. Circulation 2009; 119: 3028-3035.
5. Hamood H, Hamood R, Green MS, et al. Determinants of adherence to evidence-based therapy after acute myocardial infarction. Eur J Prev Cardiol 2016; 23: 975-985.
6. Nieuwlaat R, Schwalm JD, Khatib R, et al. Why are we failing to implement effective therapies in cardiovascular disease? Eur Heart J 2013; 34: 1262-1269.
7. Chowdhury R, Khan H, Heydon E, et al. Adherence to cardiovascular therapy: A meta-analysis of prevalence and clinical consequences. Eur Heart J 2013; 34: 2940-2948.
8. Smith A, Fortune Z, Phillips R, et al. UPBEAT study patients' perceptions of the effect of coronary heart disease on their lives: A cross-sectional sub-study. Int J Nurs Stud 2014; 51: 1500-1506.
9. Choudhry NK, Fischer MA, Avorn J, et al. The implications of therapeutic complexity on adherence to cardiovascular medications. Arch Intern Med 2011; 171: 814-822.
10. Nieuwlaat R, Wilczynski N, Navarro T, et al. Interventions for enhancing medication adherence. Cochrane Database Syst Rev 2014; (11): Art.No.: CD000011.
11. Kripalani S, Yao X, Haynes RB,. Interventions to enhance medication adherence in chronic medical conditions: A systematic review. Arch Intern Med 2007; 167: 540-550.
12. Van Dalem J, Krass I, Aslani P,. Interventions promoting adherence to cardiovascular medicines. Intl J Clin Pharm 2012; 34: 295-311.
13. Laba TL, Bleasel J, Brien JA, et al. Strategies to improve adherence to medications for cardiovascular diseases in socioeconomically disadvantaged populations: A systematic review. Int J Cardiol 2013; 167: 2430-2440.
14. Schedlbauer A, Davies P and Fahey T. Interventions to improve adherence to lipid lowering medication. Cochrane Database Syst Rev 2010; (3): Art.No.: CD004371.
15. Mansoor SM, Krass I, Aslani P,. Multiprofessional interventions to improve patient adherence to cardiovascular medications. J Cardiovasc Pharmacol Ther 2013; 18: 19-30.
16. Mahtani KR, Heneghan CJ, Glasziou PP, et al. Reminder packaging for improving adherence to self-administered long-term medications. Cochrane Database Syst Rev 2011; (9): Art. No.: CD005025.
17. Smith SC, Benjamin EJ, Bonow RO, et al. AHA/ACCF Secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease: 2011 Update: A guideline from the American Heart Association and American College of Cardiology Foundation. Circulation 2011; 124: 2458-2473.
18. Anderson JL, Adams CD, Antman EM, et al. 2011 ACCF/AHA Focused update incorporated into the ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011; 123: e426-e579.
19. Montalescot G, Sechtem U, Achenbach S, et al. 2013 ESC guidelines on the management of stable coronary artery disease. Eur Heart J 2013; 34: 2949-3003.
20. Higgins JPT, Altman DG, Gøtzsche PC, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. Br Med J 2011; 343: d5928-d5928.
21. Haynes RB, Ackloo E, Sahota N, et al. Interventions for enhancing medication adherence. Cochrane Database Syst Rev 2008; (2): Art.No.: CD000011.
22. Borenstein M, Hedges LV, Higgins JPT, et al. Multiple Outcomes or Time-Points within a Study. In: Introduction to Meta-Analysis. Chichester, UK: John Wiley & Sons, Ltd, 2009. DOI: 10.1002/9780470743386.ch25.
23. Higgins JPT, Deeks JJ and Altman DG (eds) Special topics in statistics. In: Higgins JPT, Green S (eds) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available at: www.cochrane-handbook.org.
24. Deeks JJ, Higgins JPT and Altman DG (eds) Analysing data and undertaking meta-analyses. In: Higgins JPT and Green S (eds) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available at: www.cochrane-handbook.org.
25. Duval S, Tweedie R,. Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 2000; 56: 455-463.
26. Deeks JJ, Higgins JPT and Altman DG (eds) Analysing data and undertaking meta-analyses. In: Higgins JPT and Green S (eds) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, 2011. Available at: www.cochrane-handbook.org.
27. Thakkar J, Kurup R, Laba T, et al. Mobile telephone text messaging for medication adherence in chronic disease: A meta-analysis. JAMA Intern Med 2016. Epub ahead of print 1 February 2016. DOI: 10.1001/jamainternmed.2015.7667.
28. Tao D, Xie L, Wang T, et al. A meta-analysis of the use of electronic reminders for patient adherence to medication in chronic disease care. J Telemed Telecare 2015; 21: 3-13.
29. Gould KA. A Randomized Controlled Trial of a Discharge Nursing Intervention to Promote Self-Regulation of Care for Early Discharge Interventional Cardiology Patients.
30. Choudhry NK, Avorn J, Glynn RJ, et al. Full coverage for preventive medications after myocardial infarction. N Engl J Med 2011; 365: 2088-2097.
31. Calvert SB, Kramer JM, Anstrom KJ, et al. Patient-focused intervention to improve long-term adherence to evidence-based medications: A randomized trial. Am Heart J 2012; 163: 657-65.e1-657-65.e1.
32. Gujral G, Winckel K, Nissen LM, et al. Impact of community pharmacist intervention discussing patients' beliefs to improve medication adherence. Int J Clin Pharm 2014; 36: 1048-1058.
33. Ho PM, Lambert-Kerzner A, Carey EP, et al. Multifaceted intervention to improve medication adherence and secondary prevention measures after acute coronary syndrome hospital discharge: A randomized clinical trial. JAMA Intern Med 2014; 174: 186-193.
34. Jiang X, Sit JW, Wong TK,. A nurse-led cardiac rehabilitation programme improves health behaviours and cardiac physiological risk parameters: Evidence from Chengdu, China. J Clin Nurs 2007; 16: 1886-1897.
35. Khonsari S, Subramanian P, Chinna K, et al. Effect of a reminder system using an automated short message service on medication adherence following acute coronary syndrome. Eur J Cardiovasc Nurs 2015; 14: 170-179.
36. Ma Y, Ockene IS, Rosal MC, et al. Randomized trial of a pharmacist-delivered intervention for improving lipid-lowering medication adherence among patients with coronary heart disease. Cholesterol 2010; 2010: 383281. DOI: 10.1155/2010/383281-383281. DOI: 10.1155/2010/383281.
37. Park LG, Howie-Esquivel J, Chung ML, et al. A text messaging intervention to promote medication adherence for patients with coronary heart disease: A randomized controlled trial. Patient Educ Couns 2014; 94: 261-268.
38. Polack J, Jorgenson D, Robertson P,. Evaluation of different methods of providing medication-related education to patients following myocardial infarction. Can Pharm J (Ott) 2008; 141: 241-247.
39. Rinfret S, Rodes-Cabau J, Bagur R, et al. Telephone contact to improve adherence to dual antiplatelet therapy after drug-eluting stent implantation. Heart 2013; 99: 562-569.
40. Bond C,. The MEDMAN study: A randomized controlled trial of community pharmacy-led medicines management for patients with coronary heart disease. Fam Pract 2007; 24: 189-200.
41. Castellano JM, Sanz G, Penalvo JL, et al. A polypill strategy to improve adherence: Results from the FOCUS project. J Am Coll Cardiol 2014; 64: 2071-2082.
42. Kripalani S, Schmotzer B, Jacobson TA,. Improving Medication Adherence through Graphically Enhanced Interventions in Coronary Heart Disease (IMAGE-CHD): A randomized controlled trial. J Gen Intern Med 2012; 27: 1609-1617.
43. Lourenço LB, Rodrigues RC, Ciol MA, et al. A randomized controlled trial of the effectiveness of planning strategies in the adherence to medication for coronary artery disease. J Adv Nurs 2014; 70: 1616-1628.
44. Ostbring MJ, Eriksson T, Petersson G, et al. Medication beliefs and self-reported adherence- results of a pharmacist's consultation: A pilot study. Eur J Hosp Pharm Sci Pract 2014; 21: 102-107.
45. Anglada-Martinez H, Riu-Viladoms G, Martin-Conde M, et al. Does mHealth increase adherence to medication? Results of a systematic review. Int J Clin Pract 2015; 69: 9-32.
46. Pfaeffli Dale L, Dobson R, Whittaker R, et al. The effectiveness of mobile-health behaviour change interventions for cardiovascular disease self-management: A systematic review. Eur J Prev Cardiol 2016; 23: 801-817.
47. Connor J, Rafter N, Rodgers A,. Do fixed-dose combination pills or unit-of-use packaging improve adherence? A systematic review. Bull World Health Organ 2004; 82: 935-939.
48. Cutrona SL, Choudhry NK, Fischer MA, et al. Modes of delivery for interventions to improve cardiovascular medication adherence. Am J Manag Care 2010; 16: 929-942.