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Volumn 2, Issue 1, 2015, Pages

Altered NK cell function in obese healthy humans

Author keywords

CD107a; Immunity; Leptin; Natural killer (NK) cells; Ob R; Obesity; TRAIL

Indexed keywords

FAS LIGAND; GAMMA INTERFERON; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84974578446     PISSN: None     EISSN: 20529538     Source Type: Journal    
DOI: 10.1186/s40608-014-0033-1     Document Type: Article
Times cited : (66)

References (42)
  • 2
    • 25844457693 scopus 로고    scopus 로고
    • Obesity
    • Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197-209.
    • (2005) Lancet , vol.366 , Issue.9492 , pp. 1197-1209
    • Haslam, D.W.1    James, W.P.2
  • 3
    • 0033782028 scopus 로고    scopus 로고
    • Leptin in the regulation of immunity, inflammation, and hematopoiesis
    • Fantuzzi G, Faggioni R. Leptin in the regulation of immunity, inflammation, and hematopoiesis. J Leukoc Biol. 2000;68(4):437-46.
    • (2000) J Leukoc Biol , vol.68 , Issue.4 , pp. 437-446
    • Fantuzzi, G.1    Faggioni, R.2
  • 4
    • 38949108241 scopus 로고    scopus 로고
    • Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
    • Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet. 2008;371(9612):569-78.
    • (2008) Lancet , vol.371 , Issue.9612 , pp. 569-578
    • Renehan, A.G.1    Tyson, M.2    Egger, M.3    Heller, R.F.4    Zwahlen, M.5
  • 5
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
    • Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med. 2003;348(17):1625-38.
    • (2003) N Engl J Med , vol.348 , Issue.17 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 6
    • 33748703827 scopus 로고    scopus 로고
    • Obesity and cancer risk: the role of the insulin-IGF axis
    • Renehan AG, Frystyk J, Flyvbjerg A. Obesity and cancer risk: the role of the insulin-IGF axis. Trends Endocrinol Metab. 2006;17(8):328-36.
    • (2006) Trends Endocrinol Metab , vol.17 , Issue.8 , pp. 328-336
    • Renehan, A.G.1    Frystyk, J.2    Flyvbjerg, A.3
  • 7
    • 1942436958 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis
    • Renehan AG, Zwahlen M, Minder C, O'Dwyer ST, Shalet SM, Egger M. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet. 2004;363(9418):1346-53.
    • (2004) Lancet , vol.363 , Issue.9418 , pp. 1346-1353
    • Renehan, A.G.1    Zwahlen, M.2    Minder, C.3    O'Dwyer, S.T.4    Shalet, S.M.5    Egger, M.6
  • 10
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: mediators linking adipose tissue, inflammation and immunity
    • Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol. 2006;6(10):772-83.
    • (2006) Nat Rev Immunol , vol.6 , Issue.10 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 11
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372(6505):425-32.
    • (1994) Nature , vol.372 , Issue.6505 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 13
    • 0034452029 scopus 로고    scopus 로고
    • Leptin signaling in human peripheral blood mononuclear cells, activation of p38 and p42/44 mitogen-activated protein (MAP) kinase and p70 S6 kinase
    • van den Brink GR, O'Toole T, Hardwick JC, van den Boogaardt DE, Versteeg HH, van Deventer SJ, et al. Leptin signaling in human peripheral blood mononuclear cells, activation of p38 and p42/44 mitogen-activated protein (MAP) kinase and p70 S6 kinase. Mol Cell Biol Res Commun. 2000;4(3):144-50.
    • (2000) Mol Cell Biol Res Commun , vol.4 , Issue.3 , pp. 144-150
    • van den Brink, G.R.1    O'Toole, T.2    Hardwick, J.C.3    van den Boogaardt, D.E.4    Versteeg, H.H.5    van Deventer, S.J.6
  • 14
    • 0034640508 scopus 로고    scopus 로고
    • Activation of downstream signals by the long form of the leptin receptor
    • Banks AS, Davis SM, Bates SH, Myers Jr MG. Activation of downstream signals by the long form of the leptin receptor. J Biol Chem. 2000;275(19):14563-72.
    • (2000) J Biol Chem , vol.275 , Issue.19 , pp. 14563-14572
    • Banks, A.S.1    Davis, S.M.2    Bates, S.H.3    Myers, M.G.4
  • 15
    • 61449095573 scopus 로고    scopus 로고
    • Leptin at 14 y of age: an ongoing story
    • Friedman JM. Leptin at 14 y of age: an ongoing story. Am J Clin Nutr. 2009;89(3):973S-9.
    • (2009) Am J Clin Nutr , vol.89 , Issue.3 , pp. 973S-979S
    • Friedman, J.M.1
  • 18
    • 0034628016 scopus 로고    scopus 로고
    • Human leptin enhances activation and proliferation of human circulating T lymphocytes
    • Martin-Romero C, Santos-Alvarez J, Goberna R, Sanchez-Margalet V. Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell Immunol. 2000;199(1):15-24.
    • (2000) Cell Immunol , vol.199 , Issue.1 , pp. 15-24
    • Martin-Romero, C.1    Santos-Alvarez, J.2    Goberna, R.3    Sanchez-Margalet, V.4
  • 19
    • 2442618838 scopus 로고    scopus 로고
    • The weight of leptin in immunity
    • La Cava A, Matarese G. The weight of leptin in immunity. Nat Rev Immunol. 2004;4(5):371-9.
    • (2004) Nat Rev Immunol , vol.4 , Issue.5 , pp. 371-379
    • La Cava, A.1    Matarese, G.2
  • 20
    • 0037427522 scopus 로고    scopus 로고
    • Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines
    • Zhao Y, Sun R, You L, Gao C, Tian Z. Expression of leptin receptors and response to leptin stimulation of human natural killer cell lines. Biochem Biophys Res Commun. 2003;300(2):247-52.
    • (2003) Biochem Biophys Res Commun , vol.300 , Issue.2 , pp. 247-252
    • Zhao, Y.1    Sun, R.2    You, L.3    Gao, C.4    Tian, Z.5
  • 21
    • 83455198332 scopus 로고    scopus 로고
    • Short-term and long-term leptin exposure differentially affect human natural killer cell immune functions
    • Wrann CD, Laue T, Hubner L, Kuhlmann S, Jacobs R, Goudeva L, et al. Short-term and long-term leptin exposure differentially affect human natural killer cell immune functions. Am J Physiol Endocrinol Metab. 2012;302(1):E108-16.
    • (2012) Am J Physiol Endocrinol Metab , vol.302 , Issue.1 , pp. E108-E116
    • Wrann, C.D.1    Laue, T.2    Hubner, L.3    Kuhlmann, S.4    Jacobs, R.5    Goudeva, L.6
  • 22
    • 0036431034 scopus 로고    scopus 로고
    • Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation
    • Tian Z, Sun R, Wei H, Gao B. Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation. Biochem Biophys Res Commun. 2002;298(3):297-302.
    • (2002) Biochem Biophys Res Commun , vol.298 , Issue.3 , pp. 297-302
    • Tian, Z.1    Sun, R.2    Wei, H.3    Gao, B.4
  • 23
    • 0034715948 scopus 로고    scopus 로고
    • Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population
    • Imai K, Matsuyama S, Miyake S, Suga K, Nakachi K. Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population. Lancet. 2000;356(9244):1795-9.
    • (2000) Lancet , vol.356 , Issue.9244 , pp. 1795-1799
    • Imai, K.1    Matsuyama, S.2    Miyake, S.3    Suga, K.4    Nakachi, K.5
  • 24
    • 46349104319 scopus 로고    scopus 로고
    • Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity
    • Nave H, Mueller G, Siegmund B, Jacobs R, Stroh T, Schueler U, et al. Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity. Endocrinology. 2008;149(7):3370-8.
    • (2008) Endocrinology , vol.149 , Issue.7 , pp. 3370-3378
    • Nave, H.1    Mueller, G.2    Siegmund, B.3    Jacobs, R.4    Stroh, T.5    Schueler, U.6
  • 25
    • 0034740653 scopus 로고    scopus 로고
    • CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells
    • Jacobs R, Hintzen G, Kemper A, Beul K, Kempf S, Behrens G, et al. CD56bright cells differ in their KIR repertoire and cytotoxic features from CD56dim NK cells. Eur J Immunol. 2001;31(10):3121-7.
    • (2001) Eur J Immunol , vol.31 , Issue.10 , pp. 3121-3127
    • Jacobs, R.1    Hintzen, G.2    Kemper, A.3    Beul, K.4    Kempf, S.5    Behrens, G.6
  • 26
    • 0028025074 scopus 로고
    • An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8-T cells in mice and humans
    • Lantz O, Bendelac A. An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8-T cells in mice and humans. J Exp Med. 1994;180(3):1097-106.
    • (1994) J Exp Med , vol.180 , Issue.3 , pp. 1097-1106
    • Lantz, O.1    Bendelac, A.2
  • 27
    • 69249155107 scopus 로고    scopus 로고
    • Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity
    • Lynch L, O'Shea D, Winter DC, Geoghegan J, Doherty DG, O'Farrelly C. Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity. Eur J Immunol. 2009;39(7):1893-901.
    • (2009) Eur J Immunol , vol.39 , Issue.7 , pp. 1893-1901
    • Lynch, L.1    O'Shea, D.2    Winter, D.C.3    Geoghegan, J.4    Doherty, D.G.5    O'Farrelly, C.6
  • 29
    • 0035894946 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth
    • Takeda K, Smyth MJ, Cretney E, Hayakawa Y, Yamaguchi N, Yagita H, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth. Cell Immunol. 2001;214(2):194-200.
    • (2001) Cell Immunol , vol.214 , Issue.2 , pp. 194-200
    • Takeda, K.1    Smyth, M.J.2    Cretney, E.3    Hayakawa, Y.4    Yamaguchi, N.5    Yagita, H.6
  • 30
    • 0035911242 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis
    • Smyth MJ, Cretney E, Takeda K, Wiltrout RH, Sedger LM, Kayagaki N, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis. J Exp Med. 2001;193(6):661-70.
    • (2001) J Exp Med , vol.193 , Issue.6 , pp. 661-670
    • Smyth, M.J.1    Cretney, E.2    Takeda, K.3    Wiltrout, R.H.4    Sedger, L.M.5    Kayagaki, N.6
  • 31
    • 0027937745 scopus 로고
    • Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
    • Lowin B, Hahne M, Mattmann C, Tschopp J. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature. 1994;370(6491):650-2.
    • (1994) Nature , vol.370 , Issue.6491 , pp. 650-652
    • Lowin, B.1    Hahne, M.2    Mattmann, C.3    Tschopp, J.4
  • 32
    • 0742269845 scopus 로고    scopus 로고
    • Fas (CD95/Apo-1) ligand regulation in T cell homeostasis, cell-mediated cytotoxicity and immune pathology
    • Brunner T, Wasem C, Torgler R, Cima I, Jakob S, Corazza N. Fas (CD95/Apo-1) ligand regulation in T cell homeostasis, cell-mediated cytotoxicity and immune pathology. Semin Immunol. 2003;15(3):167-76.
    • (2003) Semin Immunol , vol.15 , Issue.3 , pp. 167-176
    • Brunner, T.1    Wasem, C.2    Torgler, R.3    Cima, I.4    Jakob, S.5    Corazza, N.6
  • 33
    • 10344255635 scopus 로고    scopus 로고
    • CD107a as a functional marker for the identification of natural killer cell activity
    • Alter G, Malenfant JM, Altfeld M. CD107a as a functional marker for the identification of natural killer cell activity. J Immunol Methods. 2004;294(1-2):15-22.
    • (2004) J Immunol Methods , vol.294 , Issue.1-2 , pp. 15-22
    • Alter, G.1    Malenfant, J.M.2    Altfeld, M.3
  • 34
    • 0141629512 scopus 로고    scopus 로고
    • Nuclear war: the granzyme A-bomb
    • Lieberman J, Fan Z. Nuclear war: the granzyme A-bomb. Curr Opin Immunol. 2003;15(5):553-9.
    • (2003) Curr Opin Immunol , vol.15 , Issue.5 , pp. 553-559
    • Lieberman, J.1    Fan, Z.2
  • 35
    • 2942695902 scopus 로고    scopus 로고
    • Cytotoxic activity of the lymphocyte toxin granzyme B
    • Wowk ME, Trapani JA. Cytotoxic activity of the lymphocyte toxin granzyme B. Microbes Infect. 2004;6(8):752-8.
    • (2004) Microbes Infect , vol.6 , Issue.8 , pp. 752-758
    • Wowk, M.E.1    Trapani, J.A.2
  • 37
    • 0035071525 scopus 로고    scopus 로고
    • NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma
    • Smyth MJ, Crowe NY, Godfrey DI. NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma. Int Immunol. 2001;13(4):459-63.
    • (2001) Int Immunol , vol.13 , Issue.4 , pp. 459-463
    • Smyth, M.J.1    Crowe, N.Y.2    Godfrey, D.I.3
  • 38
    • 0037082487 scopus 로고    scopus 로고
    • Sequential production of interferon-gamma by NK1.1(+) T cells and natural killer cells is essential for the antimetastatic effect of alphagalactosylceramide
    • Smyth MJ, Crowe NY, Pellicci DG, Kyparissoudis K, Kelly JM, Takeda K, et al. Sequential production of interferon-gamma by NK1.1(+) T cells and natural killer cells is essential for the antimetastatic effect of alphagalactosylceramide. Blood. 2002;99(4):1259-66.
    • (2002) Blood , vol.99 , Issue.4 , pp. 1259-1266
    • Smyth, M.J.1    Crowe, N.Y.2    Pellicci, D.G.3    Kyparissoudis, K.4    Kelly, J.M.5    Takeda, K.6
  • 39
    • 84865399909 scopus 로고    scopus 로고
    • Immunomodulatory type II natural killer T (NKT) lymphocytes in health and disease
    • Rhost S, Sedimbi S, Kadri N, Cardell SL. Immunomodulatory type II natural killer T (NKT) lymphocytes in health and disease. Scand J Immunol. 2012;76(3):246-55.
    • (2012) Scand J Immunol , vol.76 , Issue.3 , pp. 246-255
    • Rhost, S.1    Sedimbi, S.2    Kadri, N.3    Cardell, S.L.4
  • 40
    • 0035179965 scopus 로고    scopus 로고
    • Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta
    • Sato K, Hida S, Takayanagi H, Yokochi T, Kayagaki N, Takeda K, et al. Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta. Eur J Immunol. 2001;31(11):3138-46.
    • (2001) Eur J Immunol , vol.31 , Issue.11 , pp. 3138-3146
    • Sato, K.1    Hida, S.2    Takayanagi, H.3    Yokochi, T.4    Kayagaki, N.5    Takeda, K.6
  • 41
    • 0033567099 scopus 로고    scopus 로고
    • Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells
    • Kayagaki N, Yamaguchi N, Nakayama M, Takeda K, Akiba H, Tsutsui H, et al. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J Immunol. 1999;163(4):1906-13.
    • (1999) J Immunol , vol.163 , Issue.4 , pp. 1906-1913
    • Kayagaki, N.1    Yamaguchi, N.2    Nakayama, M.3    Takeda, K.4    Akiba, H.5    Tsutsui, H.6
  • 42
    • 57349092199 scopus 로고    scopus 로고
    • Relationship between CD107a expression and cytotoxic activity
    • Aktas E, Kucuksezer UC, Bilgic S, Erten G, Deniz G. Relationship between CD107a expression and cytotoxic activity. Cell Immunol. 2009;254(2):149-54.
    • (2009) Cell Immunol , vol.254 , Issue.2 , pp. 149-154
    • Aktas, E.1    Kucuksezer, U.C.2    Bilgic, S.3    Erten, G.4    Deniz, G.5


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