The Quandary of Oral Anticoagulation in Patients With Atrial Fibrillation and Chronic Kidney Disease

American Journal of Cardiology

Volumn 117, Issue 3, 2016, Pages 477-482

  Schwartzenberg, Shmuel ^a   Lev, Eli I ^a   Sagie, Alexander ^a   Korzets, Asher ^a   Kornowski, Ran ^a  

^a HASHARON HOSPITAL   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; WARFARIN;

AMPLATZER VASCULAR PLUG; ANTICOAGULANT THERAPY; ATRIAL FIBRILLATION; BLEEDING; CEREBROVASCULAR ACCIDENT; CHRONIC KIDNEY DISEASE; CLINICAL DECISION MAKING; DRUG EFFICACY; END STAGE RENAL DISEASE; HEART ATRIUM APPENDAGE; HEART CATHETERIZATION; HUMAN; LEFT ATRIAL APPENDAGE CLOSURE DEVICE; META ANALYSIS (TOPIC); MULTICENTER STUDY (TOPIC); PATIENT RISK; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; THROMBOEMBOLISM; CHRONIC KIDNEY FAILURE; COMPLICATION; DOSE RESPONSE; HEALTH; ORAL DRUG ADMINISTRATION; PREVALENCE; STROKE;

ADMINISTRATION, ORAL; ANTICOAGULANTS; ATRIAL FIBRILLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GLOBAL HEALTH; HUMANS; PREVALENCE; RENAL INSUFFICIENCY, CHRONIC; STROKE;

EID: 84973410928     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2015.10.065     Document Type: Review

References (35)

1. 1 Wizemann, V., Tong, L., Satayathum, S., Disney, A., Akiba, T., Fissell, R.B., Kerr, P.G., Young, E.W., Robinson, B.M., Atrial fibrillation in hemodialysis patients: clinical features and associations with anticoagulant therapy. Kidney Int 77 (2010), 1098–1106.
2. 2 Winkelmayer, W.C., Patrick, A.R., Liu, J., Brookhart, M.A., Setoguchi, S., The increasing prevalence of atrial fibrillation among hemodialysis patients. J Am Soc Nephrol 22 (2011), 349–357.
3. 3 Zimmerman, D., Sood, M.M., Rigatto, C., Holden, R.M., Hiremath, S., Clase, C.M., Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysis. Nephrol Dial Transplant 27 (2012), 3816–3822.
4. 4 Landray, M.J., Wheeler, D.C., Lip, G.Y., Newman, D.J., Blann, A.D., McGlynn, F.J., Ball, S., Townend, J.N., Baigent, C., Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study. Am J Kidney Dis 43 (2004), 244–253.
5. 5 Ohishi, M., Tatara, Y., Ito, N., Takeya, Y., Onishi, M., Maekawa, Y., Kato, N., Kamide, K., Rakugi, H., The combination of chronic kidney disease and increased arterial stiffness is a predictor for stroke and cardiovascular disease in hypertensive patients. Hypertens Res 34 (2011), 1209–1215.
6. 6 Olesen, J.B., Lip, G.Y., Kamper, A.L., Hommel, K., Køber, L., Lane, D.A., Lindhardsen, J., Gislason, G.H., Torp-Pedersen, C., Stroke and bleeding in atrial fibrillation with chronic kidney disease. N Engl J Med 367 (2012), 625–635.
7. 7 Bonde, A.N., Lip, G.Y., Kamper, A.L., Hansen, P.R., Lamberts, M., Hommel, K., Hansen, M.L., Gislason, G.H., Torp-Pedersen, C., Olesen, J.B., Net clinical benefit of antithrombotic therapy in patients with atrial fibrillation and chronic kidney disease: a nationwide observational cohort study. J Am Coll Cardiol 64 (2014), 2471–2482.
8. 8 Masson, P., Webster, A.C., Hong, M., Turner, R., Lindley, R.I., Craig, J.C., Chronic kidney disease and the risk of stroke: a systematic review and meta-analysis. Nephrol Dial Transplant 30 (2015), 1162–1169.
9. 9 Benigni, A., Boccardo, P., Galbusera, M., Monteagudo, J., De Marco, L., Remuzzi, G., Ruggeri, Z.M., Reversible activation defect of the platelet glycoprotein IIb-IIIa complex in patients with uremia. Am J Kidney Dis 22 (1993), 668–676.
10. 10 Kyrle, P.A., Stockenhuber, F., Brenner, B., Gössinger, H., Korninger, C., Pabinger, I., Sunder-Plassmann, G., Balcke, P., Lechner, K., Evidence for an increased generation of prostacyclin in the microvasculature and an impairment of the platelet alpha-granule release in chronic renal failure. Thromb Haemost 60 (1988), 205–208.
11. 11 Lutz, J., Menke, J., Sollinger, D., Schinzel, H., Thürmel, K., Haemostasis in chronic kidney disease. Nephrol Dial Transplant 29 (2014), 29–40.
12. 12 Friberg, L., Benson, L., Lip, G.Y., Balancing stroke and bleeding risks in patients with atrial fibrillation and renal failure: the Swedish Atrial Fibrillation Cohort study. Eur Heart J, 2014, 297–306.
13. 13 Shah, M., Tsadok, M.A., Jackevicius, C.A., Essebag, V., Eisenberg, M.J., Rahme, E., Humphries, K.H., Tu, J.V., Behlouli, H., Guo, H., Pilote, L., Warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation undergoing dialysis. Circulation 129 (2014), 1196–1203.
14. 14 Jun, M., James, M.T., Manns, B.J., Quinn, R.R., Ravani, P., Tonelli, M., Perkovic, V., Winkelmayer, W.C., Ma, Z., Hemmelgarn, B.R., The association between kidney function and major bleeding in older adults with atrial fibrillation starting warfarin treatment: population based observational study. BMJ, 350, 2015, h246.
15. 15 Camm, A.J., Lip, G.Y., De Caterina, R., Savelieva, I., Atar, D., Hohnloser, S.H., Hindricks, G., Kirchhof, P., ESC Committee for Practice Guidelines (CPG). 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J 33 (2012), 2719–2747.
16. 16 Lip, G.Y., Nieuwlaat, R., Pisters, R., Lane, D.A., Crijns, H.J., Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest 137 (2010), 263–272.
17. 17 Pisters, R., Lane, D.A., Nieuwlaat, R., de Vos, C.B., Crijns, H.J., Lip, G.Y., A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest 138 (2010), 1093–1100.
18. 18 January, C.T., Wann, L.S., Alpert, J.S., Calkins, H., Cleveland, J.C., Cigarroa, J.E., Conti, J.B., Ellinor, P.T., Ezekowitz, M.D., Field, M.E., Murray, K.T., Sacco, R.L., Stevenson, W.G., Tchou, P.J., Tracy, C.M., Yancy, C.W., 2014 AHA/ACC/HRS Guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol 64 (2014), e1–e76.
19. 19 Winkelmayer, W.C., Liu, J., Setoguchi, S., Choudhry, N.K., Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillation. Clin J Am Soc Nephrol 6 (2011), 2662–2668.
20. 20 Carrero, J.J., Evans, M., Szummer, K., Spaak, J., Lindhagen, L., Edfors, R., Stenvinkel, P., Jacobson, S.H., Jernberg, T., Warfarin, kidney dysfunction, and outcomes following acute myocardial infarction in patients with atrial fibrillation. JAMA 311 (2014), 919–928.
21. 21 Chan, K.E., Lazarus, J.M., Thadhani, R., Hakim, R.M., Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation. J Am Soc Nephrol 20 (2009), 2223–2233.
22. 22 Morgan, C.L., McEwan, P., Tukiendorf, A., Robinson, P.A., Clemens, A., Plumb, J.M., Warfarin treatment in patients with atrial fibrillation: observing outcomes associated with varying levels of INR control. Thromb Res 124 (2009), 37–41.
23. 23 Connolly, S.J., Ezekowitz, M.D., Yusuf, S., Eikelboom, J., Oldgren, J., Parekh, A., Pogue, J., Reilly, P.A., Themeles, E., Varrone, J., Wang, S., Alings, M., Xavier, D., Zhu, J., Diaz, R., Lewis, B.S., Darius, H., Diener, H.C., Joyner, C.D., Wallentin, L., RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 361 (2009), 1139–1151.
24. 24 Patel, M.R., Mahaffey, K.W., Garg, J., Pan, G., Singer, D.E., Hacke, W., Breithardt, G., Halperin, J.L., Hankey, G.J., Piccini, J.P., Becker, R.C., Nessel, C.C., Paolini, J.F., Berkowitz, S.D., Fox, K.A., Califf, R.M., ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 365 (2011), 883–891.
25. 25 Granger, C.B., Alexander, J.H., McMurray, J.J., Lopes, R.D., Hylek, E.M., Hanna, M., Al-Khalidi, H.R., Ansell, J., Atar, D., Avezum, A., Bahit, M.C., Diaz, R., Easton, J.D., Ezekowitz, J.A., Flaker, G., Garcia, D., Geraldes, M., Gersh, B.J., Golitsyn, S., Goto, S., Hermosillo, A.G., Hohnloser, S.H., Horowitz, J., Mohan, P., Jansky, P., Lewis, B.S., Lopez-Sendon, J.L., Pais, P., Parkhomenko, A., Verheugt, F.W., Zhu, J., Wallentin, L., ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 365 (2011), 981–992.
26. 26 Hijazi, Z., Hohnloser, S.H., Oldgren, J., Andersson, U., Connolly, S.J., Eikelboom, J.W., Ezekowitz, M.D., Reilly, P.A., Siegbahn, A., Yusuf, S., Wallentin, L., Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) trial analysis. Circulation 129 (2014), 961–970.
27. 27 Hohnloser, S.H., Hijazi, Z., Thomas, L., Alexander, J.H., Amerena, J., Hanna, M., Keltai, M., Lanas, F., Lopes, R.D., Lopez-Sendon, J., Granger, C.B., Wallentin, L., Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial. Eur Heart J 33 (2012), 2821–2830.
28. 28 Hori, M., Matsumoto, M., Tanahashi, N., Momomura, S.I., Uchiyama, S., Goto, S., Izumi, T., Koretsune, Y., Kajikawa, M., Kato, M., Ueda, H., Iekushi, K., Yamanaka, S., Tajiri, M., J-ROCKET AF Study Investigators. Rivaroxaban vs. warfarin in Japanese patients with non-valvular atrial fibrillation in relation to age. Circ J 78 (2014), 1349–1356.
29. 29 Giugliano, R.P., Ruff, C.T., Braunwald, E., Murphy, S.A., Wiviott, S.D., Halperin, J.L., Waldo, A.L., Ezekowitz, M.D., Weitz, J.I., Špinar, J., Ruzyllo, W., Ruda, M., Koretsune, Y., Betcher, J., Shi, M., Grip, L.T., Patel, S.P., Patel, I., Hanyok, J.J., Mercuri, M., Antman, E.M., ENGAGE AF-TIMI 48 Investigators. Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med 369 (2013), 2093–2104.
30. 30 Connolly, S.J., Eikelboom, J., Joyner, C., Diener, H.C., Hart, R., Golitsyn, S., Flaker, G., Avezum, A., Hohnloser, S.H., Diaz, R., Talajic, M., Zhu, J., Pais, P., Budaj, A., Parkhomenko, A., Jansky, P., Commerford, P., Tan, R.S., Sim, K.H., Lewis, B.S., Van Mieghem, W., Lip, G.Y., Kim, J.H., Lanas-Zanetti, F., Gonzalez-Hermosillo, A., Dans, A.L., Munawar, M., O'Donnell, M., Lawrence, J., Lewis, G., Afzal, R., Yusuf, S., AVERROES Steering Committee and Investigators. Apixaban in patients with atrial fibrillation. N Engl J Med 364 (2011), 806–817.
31. 31 Nielsen, P.B., Lane, D.A., Rasmussen, L.H., Lip, G.Y., Larsen, T.B., Renal function and non-vitamin K oral anticoagulants in comparison with warfarin on safety and efficacy outcomes in atrial fibrillation patients: a systemic review and meta-regression analysis. Clin Res Cardiol 104 (2015), 418–429.
32. 32 Meier, B., Blaauw, Y., Khattab, A.A., Lewalter, T., Sievert, H., Tondo, C., Glikson, M., Document Reviewers. EHRA/EAPCI expert consensus statement on catheter-based left atrial appendage occlusion. Europace 16 (2014), 1397–1416.
33. 33 Reddy, V.Y., Doshi, S.K., Sievert, H., Buchbinder, M., Neuzil, P., Huber, K., Halperin, J.L., Holmes, D., Percutaneous left atrial appendage closure for stroke prophylaxis in patients with atrial fibrillation: 2.3-Year follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients with Atrial Fibrillation) Trial. Circulation 127 (2013), 720–729.
34. 34 Holmes, D.R., Kar, S., Price, M.J., Whisenant, B., Sievert, H., Doshi, S.K., Huber, K., Reddy, V.Y., Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy. J Am Coll Cardiol 64 (2014), 1–12.
35. 35 Tzikas, A., Shakir, S., Gafoor, S., Omran, H., Berti, S., Santoro, G., Kefer, J., Landmesser, U., Nielsen-Kudsk, J.E., Cruz-Gonzalez, I., Sievert, H., Tichelbäcker, T., Kanagaratnam, P., Nietlispach, F., Aminian, A., Kasch, F., Freixa, X., Danna, P., Rezzagh, M., Vermeersch, P., Stock, F., Stolcova, M., Costa, M., Ibrahim, R., Schillinger, W., Meier, B., Park, J.W., Left atrial appendage occlusion for stroke prevention in atrial fibrillation: multicentre experience with the AMPLATZER Cardiac Plug. EuroIntervention 10 (2015), 1–10.