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Volumn 1642, Issue , 2016, Pages 364-375

Towards optimized anesthesia protocols for stereotactic surgery in rats: Analgesic, stress and general health effects of injectable anesthetics. A comparison of a recommended complete reversal anesthesia with traditional chloral hydrate monoanesthesia

Author keywords

Chloral hydrate; Complete reversalanesthesia; Injectable anesthetic; Refinement

Indexed keywords

ADRENALIN; CHLORAL HYDRATE; FENTANYL; IMMUNOREACTIVE CORTICOSTERONE; ISOFLURANE; MEDETOMIDINE; MIDAZOLAM; NORADRENALIN; UNCLASSIFIED DRUG; ANESTHETIC AGENT;

EID: 84973324674     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2016.04.019     Document Type: Article
Times cited : (18)

References (55)
  • 1
    • 84906826260 scopus 로고    scopus 로고
    • Effects of isoflurane, ketamine-xylazine and a combination of medetomidine, midazolam and fentanyl on physiological variables continuously measured by telemetry in Wistar rats
    • M. Albrecht, J. Henke, S. Tacke, M. Markert, and B. Guth Effects of isoflurane, ketamine-xylazine and a combination of medetomidine, midazolam and fentanyl on physiological variables continuously measured by telemetry in Wistar rats BMC Vet. Res. 10 2014 198
    • (2014) BMC Vet. Res. , vol.10 , pp. 198
    • Albrecht, M.1    Henke, J.2    Tacke, S.3    Markert, M.4    Guth, B.5
  • 2
    • 34848813563 scopus 로고    scopus 로고
    • Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability
    • M. Arras, A. Rettich, P. Cinelli, H.P. Kasermann, and K. Burki Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability BMC Vet. Res. 3 2007 16
    • (2007) BMC Vet. Res. , vol.3 , pp. 16
    • Arras, M.1    Rettich, A.2    Cinelli, P.3    Kasermann, H.P.4    Burki, K.5
  • 3
    • 0034816055 scopus 로고    scopus 로고
    • Excretion of corticosteroid metabolites in urine and faeces of rats
    • E. Bamberg, R. Palme, and J.G. Meingassner Excretion of corticosteroid metabolites in urine and faeces of rats Lab. Anim. 35 2001 307 314
    • (2001) Lab. Anim. , vol.35 , pp. 307-314
    • Bamberg, E.1    Palme, R.2    Meingassner, J.G.3
  • 4
    • 84901326721 scopus 로고    scopus 로고
    • Mortality associated with using medetomidine and ketamine for general anesthesia in pregnant and nonpregnant Wistar rats
    • L.M. Callahan, M.L. Jones, and G.C. Musk Mortality associated with using medetomidine and ketamine for general anesthesia in pregnant and nonpregnant Wistar rats Lab. Anim. 43 6 2014 208 214
    • (2014) Lab. Anim. , vol.43 , Issue.6 , pp. 208-214
    • Callahan, L.M.1    Jones, M.L.2    Musk, G.C.3
  • 6
    • 76249127837 scopus 로고    scopus 로고
    • Effects of fentanyl pretreatment on regional cerebral blood flow in focal cerebral ischemia in rats
    • O.Z. Chi, C. Hunter, X. Liu, S.K. Chokshi, and H.R. Weiss Effects of fentanyl pretreatment on regional cerebral blood flow in focal cerebral ischemia in rats Pharmacology 85 3 2010 153 157
    • (2010) Pharmacology , vol.85 , Issue.3 , pp. 153-157
    • Chi, O.Z.1    Hunter, C.2    Liu, X.3    Chokshi, S.K.4    Weiss, H.R.5
  • 7
    • 79961205158 scopus 로고    scopus 로고
    • Involvement of endothelium-dependent and independent mechanisms in midazolam-induced vasodilation
    • G.L. Colussi, A. Di Fabio, C. Catena, A. Chiuch, and L.A. Sechi Involvement of endothelium-dependent and independent mechanisms in midazolam-induced vasodilation Hypertens. Res. 34 8 2011 929 934
    • (2011) Hypertens. Res. , vol.34 , Issue.8 , pp. 929-934
    • Colussi, G.L.1    Di Fabio, A.2    Catena, C.3    Chiuch, A.4    Sechi, L.A.5
  • 8
    • 0026580666 scopus 로고
    • Intraperitoneal injections of chloral hydrate causes intra-abdominal adhesions and unilateral testicular atrophy in golden Syrian hamsters
    • M.O. Dada, G.T. Campbell, M.J. Horacek, and C.A. Blake Intraperitoneal injections of chloral hydrate causes intra-abdominal adhesions and unilateral testicular atrophy in golden Syrian hamsters Life Sci. 51 1992 29 35
    • (1992) Life Sci. , vol.51 , pp. 29-35
    • Dada, M.O.1    Campbell, G.T.2    Horacek, M.J.3    Blake, C.A.4
  • 9
    • 77951889352 scopus 로고    scopus 로고
    • Thermoregulation: Physiological and clinical considerations during sedation and general anesthesia
    • M. Diaz, and D.E. Becker Thermoregulation: physiological and clinical considerations during sedation and general anesthesia Anesth. Prog. 57 2010 25 33
    • (2010) Anesth. Prog. , vol.57 , pp. 25-33
    • Diaz, M.1    Becker, D.E.2
  • 10
    • 0034125792 scopus 로고    scopus 로고
    • The stress response to trauma and surgery
    • J.P. Desborough The stress response to trauma and surgery Br. J. Anaesth. 85 1 2000 109 117
    • (2000) Br. J. Anaesth. , vol.85 , Issue.1 , pp. 109-117
    • Desborough, J.P.1
  • 11
    • 0027268731 scopus 로고
    • Anaesthetic effects of chloral hydrate, pentobarbitone and urethane in adult male rats
    • K.J. Field, W.J. White, and C.M. Lang Anaesthetic effects of chloral hydrate, pentobarbitone and urethane in adult male rats Lab. Anim. 27 1993 258 269
    • (1993) Lab. Anim. , vol.27 , pp. 258-269
    • Field, K.J.1    White, W.J.2    Lang, C.M.3
  • 13
    • 0028246487 scopus 로고
    • Refinement of animal use - Assessment and alleviation of pain and distress
    • P.A. Flecknell Refinement of animal use - assessment and alleviation of pain and distress Lab. Anim. 28 1994 222
    • (1994) Lab. Anim. , vol.28 , pp. 222
    • Flecknell, P.A.1
  • 15
    • 84969557535 scopus 로고    scopus 로고
    • Elsevier Amsterdam, Boston, Heidelberg, London, New York, Oxford, Paris, San Diego, San Francisco, Singapore, Sydney, Tokyo
    • P.A. Flecknell Laboratory Animal Anesthesia 3 2009 Elsevier Amsterdam, Boston, Heidelberg, London, New York, Oxford, Paris, San Diego, San Francisco, Singapore, Sydney, Tokyo
    • (2009) Laboratory Animal Anesthesia , vol.3
    • Flecknell, P.A.1
  • 16
    • 0017330432 scopus 로고
    • Adynamic ileus in the rat induced by chloral hydrate
    • R.W. Fleischmann, D. McCracken, and W. Forbes Adynamic ileus in the rat induced by chloral hydrate Lab. Anim. Sci. 27 1977 238 243
    • (1977) Lab. Anim. Sci. , vol.27 , pp. 238-243
    • Fleischmann, R.W.1    McCracken, D.2    Forbes, W.3
  • 17
    • 84973387632 scopus 로고    scopus 로고
    • Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12-and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia
    • Epub ahead of print)
    • M.C. Giroux, R. Santamaria, P. Hélie, P. Burns, F. Beaudry, and P. Vachon Physiological, pharmacokinetic and liver metabolism comparisons between 3-, 6-, 12-and 18-month-old male Sprague Dawley rats under ketamine-xylazine anesthesia Exp. Anim. 2015 2015 21 Epub ahead of print)
    • (2015) Exp. Anim. , vol.2015 , pp. 21
    • Giroux, M.C.1    Santamaria, R.2    Hélie, P.3    Burns, P.4    Beaudry, F.5    Vachon, P.6
  • 18
    • 43549125008 scopus 로고    scopus 로고
    • Effects of the kynurenine 3-hydroxylase inhibitor Ro 61-8048 after intrastriatal injections on the severity of dystonia in the dt(sz) mutant
    • M. Hamann, S.E. Sander, and A. Richter Effects of the kynurenine 3-hydroxylase inhibitor Ro 61-8048 after intrastriatal injections on the severity of dystonia in the dt(sz) mutant Eur. J. Pharmacol. 586 2008 156 159
    • (2008) Eur. J. Pharmacol. , vol.586 , pp. 156-159
    • Hamann, M.1    Sander, S.E.2    Richter, A.3
  • 19
    • 0026546888 scopus 로고
    • Fentanyl and medetomidine anaesthesia in the rat and its reversal using atipamazole and either nalbuphine or butorphanol
    • C. Hu, P.A. Flecknell, and J.H. Liles Fentanyl and medetomidine anaesthesia in the rat and its reversal using atipamazole and either nalbuphine or butorphanol Lab. Anim. 26 1992 15 22
    • (1992) Lab. Anim. , vol.26 , pp. 15-22
    • Hu, C.1    Flecknell, P.A.2    Liles, J.H.3
  • 20
    • 67650297226 scopus 로고    scopus 로고
    • Evaluation of the anaesthetic effects of medetomidine and ketamine in rats and their reversal with atipamezole
    • H.S. Jang, H.S. Choi, H.L.H. Sung, and K. Jang Evaluation of the anaesthetic effects of medetomidine and ketamine in rats and their reversal with atipamezole Vet. Anaesth. Anal. 36 2009 319 327
    • (2009) Vet. Anaesth. Anal. , vol.36 , pp. 319-327
    • Jang, H.S.1    Choi, H.S.2    Sung, H.L.H.3    Jang, K.4
  • 21
    • 85047675030 scopus 로고    scopus 로고
    • Ultrasonic vocalizations as indices of affective states in rats
    • B. Knutson, J. Burgdorf, and J. Panksepp Ultrasonic vocalizations as indices of affective states in rats Psychol. Bull. 128 6 2002 961 977
    • (2002) Psychol. Bull. , vol.128 , Issue.6 , pp. 961-977
    • Knutson, B.1    Burgdorf, J.2    Panksepp, J.3
  • 22
    • 0037193719 scopus 로고    scopus 로고
    • Degrees of aversion shown by rats and mice to different concentrations of inhalational anaesthetics
    • M.C. Leach, V.A. Bowell, T.F. Allan, and D.B. Morton Degrees of aversion shown by rats and mice to different concentrations of inhalational anaesthetics Vet. Rec. 150 26 2002 808 815
    • (2002) Vet. Rec. , vol.150 , Issue.26 , pp. 808-815
    • Leach, M.C.1    Bowell, V.A.2    Allan, T.F.3    Morton, D.B.4
  • 23
    • 34547575538 scopus 로고    scopus 로고
    • Non-invasive measurement of adrenocortical activity in male and female rats
    • M. Lepschy, C. Touma, R. Hruby, and R. Palme Non-invasive measurement of adrenocortical activity in male and female rats Lab. Anim. 41 2007 372 387
    • (2007) Lab. Anim. , vol.41 , pp. 372-387
    • Lepschy, M.1    Touma, C.2    Hruby, R.3    Palme, R.4
  • 26
    • 84878158524 scopus 로고    scopus 로고
    • Ketamine pharmacology: An update (pharmacodynamics and molecular aspects, recent findings)
    • G. Mion, and T. Villevieille Ketamine pharmacology: an update (pharmacodynamics and molecular aspects, recent findings) CNS Neurosci. Ther. 19 6 2013 370 380
    • (2013) CNS Neurosci. Ther. , vol.19 , Issue.6 , pp. 370-380
    • Mion, G.1    Villevieille, T.2
  • 27
    • 0022429302 scopus 로고
    • Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis of assessment
    • D.B. Morton, and P.H. Griffiths Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis of assessment Vet. Rec. 116 1985 431 436
    • (1985) Vet. Rec. , vol.116 , pp. 431-436
    • Morton, D.B.1    Griffiths, P.H.2
  • 28
    • 33748375822 scopus 로고    scopus 로고
    • Neurophysiological techniques to assess pain in animals
    • J.C. Murrell, and C.B. Johnson Neurophysiological techniques to assess pain in animals J. Vet. Pharmacol. Ther. 29 2006 325 335
    • (2006) J. Vet. Pharmacol. Ther. , vol.29 , pp. 325-335
    • Murrell, J.C.1    Johnson, C.B.2
  • 29
    • 33746506178 scopus 로고    scopus 로고
    • The dose-dependent effects of isoflurane on outcome from severe forebrain ischemia in the rat
    • I. Nasu, N. Yokoo, S. Takaoka, K. Takata, T. Hoshikawa, M. Okada, and Y. Miura The dose-dependent effects of isoflurane on outcome from severe forebrain ischemia in the rat Anesth. Analg. 103 2 2006 413 418
    • (2006) Anesth. Analg. , vol.103 , Issue.2 , pp. 413-418
    • Nasu, I.1    Yokoo, N.2    Takaoka, S.3    Takata, K.4    Hoshikawa, T.5    Okada, M.6    Miura, Y.7
  • 30
    • 23144447667 scopus 로고    scopus 로고
    • Hemodynamic and catecholamine response to a rapid increase in isoflurane or sevoflurane concentration during a maintenance phase of anesthesia in humans
    • T. Nishiyama Hemodynamic and catecholamine response to a rapid increase in isoflurane or sevoflurane concentration during a maintenance phase of anesthesia in humans J. Anesth. 19 3 2005 213 217
    • (2005) J. Anesth. , vol.19 , Issue.3 , pp. 213-217
    • Nishiyama, T.1
  • 31
    • 39449129868 scopus 로고    scopus 로고
    • Intraoperative und postoperative Schmerzerkennung und -überwachung
    • K.A. Otto Intraoperative und postoperative Schmerzerkennung und -überwachung Tierärztl. Prax. 26 2008 12 18
    • (2008) Tierärztl. Prax. , vol.26 , pp. 12-18
    • Otto, K.A.1
  • 32
    • 84921341262 scopus 로고    scopus 로고
    • Limits to using HPA axis activity as an indication of animal welfare
    • P. Otovic, and E. Hutchinson Limits to using HPA axis activity as an indication of animal welfare Altex 32 2015 41
    • (2015) Altex , vol.32 , pp. 41
    • Otovic, P.1    Hutchinson, E.2
  • 33
    • 0942268822 scopus 로고    scopus 로고
    • Neuroprotective properties of different anesthetics on axotomized rat retinal ganglion cells in vivo
    • S. Ozden, and S. Isenmann Neuroprotective properties of different anesthetics on axotomized rat retinal ganglion cells in vivo J. Neurotrauma 21 2004 73
    • (2004) J. Neurotrauma , vol.21 , pp. 73
    • Ozden, S.1    Isenmann, S.2
  • 34
    • 23744437308 scopus 로고    scopus 로고
    • Measuring fecal steroids: Guidelines for practical application
    • R. Palme Measuring fecal steroids: guidelines for practical application Ann. N Y Acad. Sci. 1046 2005 75 80
    • (2005) Ann. N y Acad. Sci. , vol.1046 , pp. 75-80
    • Palme, R.1
  • 35
    • 22144489480 scopus 로고    scopus 로고
    • Stress hormones in mammals and birds: Comparative aspects regarding metabolism, excretion, and noninvasive measurement in fecal samples
    • R. Palme, S. Rettenbacher, C. Touma, S.M. El-Bahr, and E. Möstl Stress hormones in mammals and birds: comparative aspects regarding metabolism, excretion, and noninvasive measurement in fecal samples Ann. N Y Acad. Sci. 1040 2005 162 171
    • (2005) Ann. N y Acad. Sci. , vol.1040 , pp. 162-171
    • Palme, R.1    Rettenbacher, S.2    Touma, C.3    El-Bahr, S.M.4    Möstl, E.5
  • 38
    • 37349085745 scopus 로고    scopus 로고
    • Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice
    • F. Richter, M. Hamann, and A. Richter Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice Brain Res. 1188 2008 148 156
    • (2008) Brain Res. , vol.1188 , pp. 148-156
    • Richter, F.1    Hamann, M.2    Richter, A.3
  • 39
    • 33748429013 scopus 로고    scopus 로고
    • Differential effects of chloral hydrat- and ketmain/xylazin-induced anesthesia by the S.C. Route
    • S.F. Rodrigues, M. Aparecida de Oliviera, and J.O. Martins Differential effects of chloral hydrat- and ketmain/xylazin-induced anesthesia by the s.c. route Life Sci. 79 2006 1630 1637
    • (2006) Life Sci. , vol.79 , pp. 1630-1637
    • Rodrigues, S.F.1    Aparecida De Oliviera, M.2    Martins, J.O.3
  • 40
    • 0842281932 scopus 로고    scopus 로고
    • Impact of chronic catherization and automated blood samling (Accusampler) on serum corticosterone and fecal immunoreactive corticorticosterone metabolites and immunoglobulin A in male rats
    • F. Royo, N. Björk, H.E. Carlsson, S. Mayo, and J. Hau Impact of chronic catherization and automated blood samling (Accusampler) on serum corticosterone and fecal immunoreactive corticorticosterone metabolites and immunoglobulin A in male rats J. Endocrinol. 180 2004 145 153
    • (2004) J. Endocrinol. , vol.180 , pp. 145-153
    • Royo, F.1    Björk, N.2    Carlsson, H.E.3    Mayo, S.4    Hau, J.5
  • 41
    • 34247142452 scopus 로고    scopus 로고
    • Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant
    • S.E. Sander, and A. Richter Effects of intrastriatal injections of glutamate receptor antagonists on the severity of paroxysmal dystonia in the dtsz mutant Eur. J. Pharmacol. 563 2007 102 108
    • (2007) Eur. J. Pharmacol. , vol.563 , pp. 102-108
    • Sander, S.E.1    Richter, A.2
  • 42
    • 0346270285 scopus 로고    scopus 로고
    • A review of the physiological effects of alpha2-agonists related to the clinical use of medetomidine in small animal practice
    • M.D. Sinclair A review of the physiological effects of alpha2-agonists related to the clinical use of medetomidine in small animal practice Can. Vet. J. 44 11 2003 885 897
    • (2003) Can. Vet. J. , vol.44 , Issue.11 , pp. 885-897
    • Sinclair, M.D.1
  • 43
    • 0025124501 scopus 로고
    • Tissue response to intramuscular and intraperitoneal injections of ketamine and xylazine in rats
    • K.L. Smiler, S. Stein, K.L. Hrapkiewicz, and J.R. Hiben Tissue response to intramuscular and intraperitoneal injections of ketamine and xylazine in rats Lab. Anim. Sci. 40 1 1990 60 64
    • (1990) Lab. Anim. Sci. , vol.40 , Issue.1 , pp. 60-64
    • Smiler, K.L.1    Stein, S.2    Hrapkiewicz, K.L.3    Hiben, J.R.4
  • 44
    • 33646229080 scopus 로고    scopus 로고
    • Isoflurane leakage from non-rebreathing rodent anaesthesia circuits: Comparison of emissions from conventional and modified ports
    • J.C. Smith, and B. Bolon Isoflurane leakage from non-rebreathing rodent anaesthesia circuits: comparison of emissions from conventional and modified ports Lab. Anim. 40 2006 200 209
    • (2006) Lab. Anim. , vol.40 , pp. 200-209
    • Smith, J.C.1    Bolon, B.2
  • 45
    • 0041419475 scopus 로고    scopus 로고
    • Species-specific assessment of pain in laboratory animals. Contemporary Topics in
    • K.L. Stasiak, D. Maul, E. French, P.W. Hellyer, and S. VandeWoude Species-specific assessment of pain in laboratory animals. Contemporary Topics in Lab. Anim. Sci. 42 4 2003 13 20
    • (2003) Lab. Anim. Sci. , vol.42 , Issue.4 , pp. 13-20
    • Stasiak, K.L.1    Maul, D.2    French, E.3    Hellyer, P.W.4    VandeWoude, S.5
  • 46
    • 63849324194 scopus 로고    scopus 로고
    • Reported analgesic and anaesthetic administration to rodents undergoing experimental surgical procedures
    • E.L. Stokes, P.A. Flecknell, and C.A. Richardson Reported analgesic and anaesthetic administration to rodents undergoing experimental surgical procedures Lab. Anim. 43 2009 149 154
    • (2009) Lab. Anim. , vol.43 , pp. 149-154
    • Stokes, E.L.1    Flecknell, P.A.2    Richardson, C.A.3
  • 47
    • 84973327058 scopus 로고    scopus 로고
    • Schmerzerkennung und Schmerzmanagement bei Hund, Katze und Heimtier
    • S. Tacke, J. Reinert, and J. Henke Schmerzerkennung und Schmerzmanagement bei Hund, Katze und Heimtier Fachpraxis 51 2007 4 16
    • (2007) Fachpraxis , vol.51 , pp. 4-16
    • Tacke, S.1    Reinert, J.2    Henke, J.3
  • 48
    • 36048963222 scopus 로고    scopus 로고
    • Study of two devices used to maintain normothermia in rats and mice during general anesthesia
    • D.K. Taylor Study of two devices used to maintain normothermia in rats and mice during general anesthesia J. Am. Assoc. Lab. Anim. Sci. 46 5 2007 37 41
    • (2007) J. Am. Assoc. Lab. Anim. Sci. , vol.46 , Issue.5 , pp. 37-41
    • Taylor, D.K.1
  • 49
    • 0033965875 scopus 로고    scopus 로고
    • A pathophysiological study of abdominal organs following intraperitoneal injections of chloral hydrate in rats: Comparison between two anaesthesia protocols
    • P. Vachon, S. Faubert, D. Blais, A. Comtois, and J.G. Bienvenu A pathophysiological study of abdominal organs following intraperitoneal injections of chloral hydrate in rats: comparison between two anaesthesia protocols Lab. Anim. 34 2000 84 90
    • (2000) Lab. Anim. , vol.34 , pp. 84-90
    • Vachon, P.1    Faubert, S.2    Blais, D.3    Comtois, A.4    Bienvenu, J.G.5
  • 50
    • 77952481586 scopus 로고    scopus 로고
    • Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice
    • A. Waite, S.C. Gilliver, G.R. Masterson, M.J. Hardman, and G.S. Ashcroft Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice Br. J. Anaesth. 104 6 2010 768 773
    • (2010) Br. J. Anaesth. , vol.104 , Issue.6 , pp. 768-773
    • Waite, A.1    Gilliver, S.C.2    Masterson, G.R.3    Hardman, M.J.4    Ashcroft, G.S.5
  • 51
    • 0019403182 scopus 로고
    • Role of sympathetic system in morphine-induced mydriasis in rat
    • M.C. Wallenstein Role of sympathetic system in morphine-induced mydriasis in rat Am. J. Physiol. 241 3 1981 R130 R135
    • (1981) Am. J. Physiol. , vol.241 , Issue.3 , pp. R130-R135
    • Wallenstein, M.C.1
  • 52
    • 0023626134 scopus 로고
    • The effects of pentobarbital, fentanyl-droperidol, ketamine-xylazine and ketamine-diazepam on core and surface body temperature regulation in adult male rats
    • S.K. Wixson, W.J. White, H.C. Hughes, C.M. Lang, and W.K. Marshall The effects of pentobarbital, fentanyl-droperidol, ketamine-xylazine and ketamine-diazepam on core and surface body temperature regulation in adult male rats Lab. Anim. Sci. 37 6 1987 743 749
    • (1987) Lab. Anim. Sci. , vol.37 , Issue.6 , pp. 743-749
    • Wixson, S.K.1    White, W.J.2    Hughes, H.C.3    Lang, C.M.4    Marshall, W.K.5
  • 54
    • 1542306612 scopus 로고    scopus 로고
    • Rat sex differences in anesthesia
    • E.A. Zambricki, and L.G. Dalecy Rat sex differences in anesthesia Comp. Med. 54 2004 49
    • (2004) Comp. Med. , vol.54 , pp. 49
    • Zambricki, E.A.1    Dalecy, L.G.2
  • 55
    • 84923223929 scopus 로고    scopus 로고
    • The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats
    • J. Zhang, H. Tan, W. Jiang, and Z. Zuo The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats J Neuroimmune Pharmacol. 10 1 2015 179 189
    • (2015) J Neuroimmune Pharmacol. , vol.10 , Issue.1 , pp. 179-189
    • Zhang, J.1    Tan, H.2    Jiang, W.3    Zuo, Z.4


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