Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 23, 2016, Pages 6544-6549

  Li, Wen ^a   Englund, Elisabet ^b   Widner, Håkan ^b   Mattsson, Bengt ^a   Van Westen, Danielle ^b   Lätt, Jimmy ^b   Rehncrona, Stig ^b   Brundin, Patrik ^c   Björklund, Anders ^a   Lindvall, Olle ^b   Li, Jia Yi ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

Autopsy; Parkinson's disease; Reinnervation; Synucleinopathy; Transplantation

Indexed keywords

ALPHA SYNUCLEIN; CD68 ANTIGEN; DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA; NEUROMELANIN; UBIQUITIN; VESICULAR MONOAMINE TRANSPORTER 2; DOPAMINE;

ADULT; ARTICLE; AUTOPSY; CELL SURVIVAL; CELL TRANSPLANTATION; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; DOPAMINERGIC NERVE CELL; DOPAMINERGIC NERVE CELL TRANSPLANTATION; DOWN REGULATION; DYSKINESIA; EMBRYO; FOLLOW UP; HEART FAILURE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOKINESIA; IMMUNE RESPONSE; IMMUNOREACTIVITY; LOW DRUG DOSE; MALE; MICROGLIA; MIDDLE AGED; MOTOR PERFORMANCE; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; PUTAMEN; REINNERVATION; RIGIDITY; SUBSTANTIA NIGRA; TREMOR; WHITE MATTER; CORPUS STRIATUM; EMBRYOLOGY; FETAL TISSUE TRANSPLANTATION; MESENCEPHALON; NERVE CELL;

ALPHA-SYNUCLEIN; CORPUS STRIATUM; DOPAMINE; FETAL TISSUE TRANSPLANTATION; HUMANS; MESENCEPHALON; NEURONS; PARKINSON DISEASE; PUTAMEN;

EID: 84973324671     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1605245113     Document Type: Article

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