Glycaemic control, glucose variability and the triangle of diabetes care

British Journal of Diabetes and Vascular Disease

Volumn 16, Issue , 2016, Pages S3-S6

  Rayman, Gerry ^a  

^a IPSWICH HOSPITAL   (United Kingdom)

Author keywords

Diabetes complications; Glucose monitoring; Glucose variability; Glycosylated haemoglobin; Hypoglycaemia

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN;

DIABETES CONTROL; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; GLUCOSE VARIABILITY; GLYCEMIC CONTROL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; METABOLIC PARAMETERS; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT CARE; QUALITY OF LIFE; REVIEW; RISK REDUCTION; SELF MONITORING;

EID: 84971443009     PISSN: 14746514     EISSN: 17534305     Source Type: Journal    
DOI: 10.15277/bjd.2016.070     Document Type: Review

References (20)

1. Bliss M. The Discovery of Insulin. University of Chicago Press, p. 152.
2. Ainsberg A. Breakthrough - the story of Elizabeth Hughes and the making of a medical miracle. Available at https://www.idf.org/sites/default/files/attachments/DV-56-SI2-Ainsberg.pdf (accessed December 2015).
3. Gebel E. The start of something good: the discovery of HbA (1c) and the American Diabetes Association Samuel Rahbar Outstanding Discovery Award. Diabetes Care 2012;35:2429-31. http://dx.doi.org/10.2337/dc12-1763
4. Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 2015;58:429-42. http://dx.doi.org/10.1007/s00125-014-3460-0
5. Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-86. http://dx.doi.org/10.1056/NEJM199309303291401
6. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-53. http://dx.doi.org/10.1016/S0140-6736 (98) 07019-6
7. Holman RR, Paul SK, Bethel MA, et al. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008;359:1577-89. http://dx.doi.org/10.1056/NEJMoa0806470
8. Nathan DM; DCCT/EDIC Research Group. The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: overview. Diabetes Care 2014;37:9-16. http://dx.doi.org/10.2337/dc13-2112
9. Cefalu WT, Ratner RE. The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: the "gift" that keeps on giving! Diabetes Care 2014;37:5-7. http://dx.doi.org/10.2337/dc13-2369
10. Frier BM, Jensen MM, Chubb BD. Hypoglycaemia in adults with insulintreated diabetes in the UK: self-reported frequency and effects. Diabet Med 2015 (advance online, http://dx.doi.org/10.1111/dme.12878).
11. Ceriello A, Kilpatrick ES. Glycemic variability: both sides of the story. Diabetes Care 2013;36 Suppl 2:S272-5. http://dx.doi.org/10.2337/dcS13-2030
12. Lachin JM, Genuth S, Nathan DM, Zinman B, Rutledge BN; DCCT/EDIC Research Group. The effect of glycemic exposure on the risk of microvascular complications in the diabetes control and complications trial-revisited. Diabetes 2008;57:995-1001. http://dx.doi.org/10.2337/db07-1618
13. Frontoni S, Di Bartolo P, Avogaro A, et al. Glucose variability: An emerging target for the treatment of diabetes mellitus. Diabetes Res Clin Pract 2013;102:86-95. http://dx.doi.org/10.1016/j.diabres.2013.09.007
14. Ceriello A, Novials A, Ortega E, et al. Hyperglycemia following recovery from hypoglycemia worsens endothelial damage and thrombosis activation in type 1 diabetes and in healthy controls. Nutr Metab Cardiovasc Dis 2014;24:116-23. http://dx.doi.org/10.1016/j.numecd.2013.05.003
15. Almaatouq MA, Al-Arouj M, Amod A, et al. Barriers to the delivery of optimal antidiabetic therapy in the Middle East and Africa. Int J Clin Pract 2014;68:503-11. http://dx.doi.org/10.1111/ijcp. 12342
16. Frier BM. Hypoglycaemia in diabetes mellitus: epidemiology and clinical implications. Nat Rev Endocrinol 2014;10:711-22. http://dx.doi.org/10.1038/nrendo.2014.170
17. Paty BW. The role of hypoglycemia in cardiovascular outcomes in diabetes. Can J Diabetes 2015;39 Suppl 5:S155-S159. http://dx.doi.org/10.1016/j.jcjd.2015.09.009
18. Cryer PE. Severe hypoglycemia predicts mortality in diabetes. Diabetes Care 2012;35:1814-6. http://dx.doi.org/10.2337/dc12-0749
19. Diabetes Control and Complications Trial Research Group. Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 1997;46:271-86. http://dx.doi.org/10.2337/diab.46.2.271
20. Bergenstal RM, Klonoff DC, Garg SK, et al. Threshold-based insulinpump interruption for reduction of hypoglycemia. N Engl J Med 2013;369:224-32. http://dx.doi.org/10.1056/NEJMoa1303576