Diffuse Alveolar Hemorrhage Secondary to Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Predictors of Respiratory Failure and Clinical Outcomes

Arthritis and Rheumatology

Volumn 68, Issue 6, 2016, Pages 1467-1476

  Cartin Ceba, Rodrigo ^a   Diaz Caballero, Luis ^b   Al Qadi, Mazen O ^c   Tryfon, Stavros ^d   Fervenza, Fernando C ^a   Ytterberg, Steven R ^a   Specks, Ulrich ^a  

^a MAYO CLINIC   (United States)

^b Macon Lung Center   (United States)

^c BROWN UNIVERSITY   (United States)

^d Aristotle University of Thessaloniki   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CARBON MONOXIDE; CREATININE; CYCLOPHOSPHAMIDE; GLUCOCORTICOID; HEMOGLOBIN; METHYLPREDNISOLONE; MYCOPHENOLATE MOFETIL; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; PREDNISONE; RITUXIMAB; IMMUNOLOGIC FACTOR; IMMUNOSUPPRESSIVE AGENT;

ADULT; ANCA ASSOCIATED VASCULITIS; ARTICLE; ARTIFICIAL VENTILATION; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CLINICAL ASSESSMENT; CLINICAL EVALUATION; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DIFFUSE LUNG HEMORRHAGE; DISEASE ASSOCIATION; DRUG EFFICACY; FEMALE; HUMAN; HYPOXEMIA; LUNG HEMORRHAGE; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; OUTCOME ASSESSMENT; PLASMAPHERESIS; PRIORITY JOURNAL; REMISSION; RESPIRATORY FAILURE; THERAPY EFFECT; TREATMENT DURATION; AGED; COMPARATIVE STUDY; COMPLICATION; HEMORRHAGE; LUNG ALVEOLUS; LUNG DISEASES; MIDDLE AGED; PLASMA EXCHANGE; RESPIRATORY INSUFFICIENCY; TREATMENT OUTCOME;

AGED; ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED VASCULITIS; COHORT STUDIES; CYCLOPHOSPHAMIDE; FEMALE; HEMORRHAGE; HUMANS; IMMUNOLOGIC FACTORS; IMMUNOSUPPRESSIVE AGENTS; LUNG DISEASES; MALE; MIDDLE AGED; PLASMA EXCHANGE; PULMONARY ALVEOLI; REMISSION INDUCTION; RESPIRATORY INSUFFICIENCY; RITUXIMAB; TREATMENT OUTCOME;

EID: 84971323646     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39562     Document Type: Article

References (34)

1. Krause ML, Cartin-Ceba R, Specks U, Peikert T., Update on diffuse alveolar hemorrhage and pulmonary vasculitis. Immunol Allergy Clin North Am 2012; 32: 587-600.
2. Lara AR, Schwarz MI., Diffuse alveolar hemorrhage. Chest 2010; 137: 1164-71.
3. Lee AS, Specks U., Pulmonary capillaritis. Semin Respir Crit Care Med 2004; 25: 547-55.
4. Specks U., Diffuse alveolar hemorrhage syndromes. Curr Opin Rheumatol 2001; 13: 12-7.
5. Casian A, Jayne D., Management of alveolar hemorrhage in lung vasculitides. Semin Respir Crit Care Med 2011; 32: 335-45.
6. Jones RB, Tervaert JW, Hauser T, Luqmani R, Morgan MD, Peh CA, et al., Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis. N Engl J Med 2010; 363: 211-20.
7. Stone JH, Merkel PA, Spiera R, Seo P, Langford CA, Hoffman GS, et al., Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med 2010; 363: 221-32.
8. Chen M, Zhao MH., Severe pulmonary hemorrhage in patients with end-stage renal disease in antineutrophil cytoplasmic autoantibody-associated vasculitis. Am J Med Sci 2009; 337: 411-4.
9. Hruskova Z, Casian AL, Konopasek P, Svobodova B, Frausova D, Lanska V, et al., Long-term outcome of severe alveolar haemorrhage in ANCA-associated vasculitis: a retrospective cohort study. Scand J Rheumatol 2013; 42: 211-4.
10. Klemmer PJ, Chalermskulrat W, Reif MS, Hogan SL, Henke DC, Falk RJ., Plasmapheresis therapy for diffuse alveolar hemorrhage in patients with small-vessel vasculitis. Am J Kidney Dis 2003; 42: 1149-53.
11. Lin Y, Zheng W, Tian X, Zhang X, Zhang F, Dong Y., Antineutrophil cytoplasmic antibody-associated vasculitis complicated with diffuse alveolar hemorrhage: a study of 12 cases. J Clin Rheumatol 2009; 15: 341-4.
12. Ravindran V, Watts RA., Pulmonary haemorrhage in ANCA-associated vasculitis. Rheumatology (Oxford) 2010; 49: 1410-2.
13. Gallagher H, Kwan JT, Jayne DR., Pulmonary renal syndrome: a 4-year, single-center experience. Am J Kidney Dis 2002; 39: 42-7.
14. Lauque D, Cadranel J, Lazor R, Pourrat J, Ronco P, Guillevin L, et al, the Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P). Microscopic polyangiitis with alveolar hemorrhage: a study of 29 cases and review of the literature. Medicine (Baltimore) 2000; 79: 222-33.
15. Ter Maaten JC, Franssen CF, Gans RO, van Schijndel RJ, Hoorntje SJ., Respiratory failure in ANCA-associated vasculitis. Chest 1996; 110: 357-62.
16. Haworth SJ, Savage CO, Carr D, Hughes JM, Rees AJ., Pulmonary haemorrhage complicating Wegener's granulomatosis and microscopic polyarteritis. Br Med J (Clin Res Ed) 1985; 290: 1775-8.
17. Kostianovsky A, Hauser T, Pagnoux C, Cohen P, Daugas E, Mouthon L, et al., Alveolar haemorrhage in ANCA-associated vasculitides: 80 patients' features and prognostic factors. Clin Exp Rheumatol 2012; 30 Suppl 70: S77-82.
18. Jennette JC, Falk RJ, Andrassy K, Bacon PA, Churg J, Gross WL, et al., Nomenclature of systemic vasculitides: proposal of an international consensus conference. Arthritis Rheum 1994; 37: 187-92.
19. Leavitt RY, Fauci AS, Bloch DA, Michel BA, Hunder GG, Arend WP, et al., The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis. Arthritis Rheum 1990; 33: 1101-7.
20. Merkel PA, Cuthbertson DD, Hellmich B, Hoffman GS, Jayne DR, Kallenberg CG, et al., Comparison of disease activity measures for anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis. Ann Rheum Dis 2009; 68: 103-6.
21. Stone JH, Hoffman GS, Merkel PA, Min YI, Uhlfelder ML, Hellmann DB, et al, for the International Network for the Study of the Systemic Vasculitides (INSSYS). A disease-specific activity index for Wegener's granulomatosis: modification of the Birmingham Vasculitis Activity Score. Arthritis Rheum 2001; 44: 912-20.
22. Knaus WA, Wagner DP, Draper EA, Zimmerman JE, Bergner M, Bastos PG, et al., The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults. Chest 1991; 100: 1619-36.
23. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB., Comparison of the SpO2/FIO2 ratio and the PaO2/FIO2 ratio in patients with acute lung injury or ARDS. Chest 2007; 132: 410-7.
24. Esteban A, Anzueto A, Frutos F, Alia I, Brochard L, Stewart TE, et al., Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA 2002; 287: 345-55.
25. Vincent JL, Akca S, de Mendonca A, Haji-Michael P, Sprung C, Moreno R, et al., The epidemiology of acute respiratory failure in critically ill patients(∗). Chest 2002; 121: 1602-9.
26. Austin PC., An introduction to propensity score methods for reducing the effects of confounding in observational studies. Multivariate Behav Res 2011; 46: 399-424.
27. Vincent JL, de Mendonca A, Cantraine F, Moreno R, Takala J, Suter PM, et al, working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Crit Care Med 1998; 26: 1793-800.
28. Moreno R, Vincent JL, Matos R, Mendonca A, Cantraine F, Thijs L, et al, Working Group on Sepsis related Problems of the ESICM. The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care: results of a prospective, multicentre study. Intensive Care Med 1999; 25: 686-96.
29. Walsh M, Catapano F, Szpirt W, Thorlund K, Bruchfeld A, Guillevin L, et al., Plasma exchange for renal vasculitis and idiopathic rapidly progressive glomerulonephritis: a meta-analysis. Am J Kidney Dis 2011; 57: 566-74.
30. Zauner I, Bach D, Braun N, Kramer BK, Funfstuck R, Helmchen U, et al., Predictive value of initial histology and effect of plasmapheresis on long-term prognosis of rapidly progressive glomerulonephritis. Am J Kidney Dis 2002; 39: 28-35.
31. Szpirt WM, Heaf JG, Petersen J., Plasma exchange for induction and cyclosporine A for maintenance of remission in Wegener's granulomatosis: a clinical randomized controlled trial. Nephrol Dial Transplant 2011; 26: 206-13.
32. Pusey CD, Rees AJ, Evans DJ, Peters DK, Lockwood CM., Plasma exchange in focal necrotizing glomerulonephritis without anti-GBM antibodies. Kidney Int 1991; 40: 757-63.
33. Plasma Exchange and Glucocorticoids for Treatment of Anti-Neutrophil Cytoplasm Antibody (ANCA)-Associated Vasculitis (PEXIVAS) Trial 2014. URL: https://clinicaltrials.gov/ct2/show/NCT00987389.
34. Westman K, Flossmann O, Gregorini G., The long-term outcomes of systemic vasculitis. Nephrol Dial Transplant 2015; 30 Suppl 1: i60-6.