PM100117 and PM100118, new antitumor macrolides produced by a marine Streptomyces caniferus GUA-06-05-006A

Journal of Antibiotics

Volumn 69, Issue 5, 2016, Pages 388-394

  Pérez, Marta ^a,b   Schleissner, Carmen ^a   Fernández, Rogelio ^a   Rodríguez, Pilar ^a   Reyes, Fernando ^a   Zuñiga, Paz ^a   De La Calle, Fernando ^a   Cuevas, Carmen ^a  

^a Colmenar Viejo ^*  (Spain)

^b PHARMAMAR S A   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 NAPHTHOQUINONE; ANTINEOPLASTIC AGENT; DEOXYSUGAR; MACROLIDE; PM 100117; PM 100118; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; PM100117; PM100118;

A549 CELL LINE; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BACTERIAL CHROMATOPHORE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM ISOLATION; BREAST CANCER CELL LINE; CANDIDA ALBICANS; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HT 29 CELL LINE; HUMAN; HUMAN CELL; LC50; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STREPTOMYCES; STREPTOMYCES CANIFERUS; TUMOR CELL LINE; A-549 CELL LINE; BREAST NEOPLASMS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; COLONIC NEOPLASMS; DRUG EFFECTS; FEMALE; ISOLATION AND PURIFICATION; LUNG NEOPLASMS; METABOLISM;

A549 CELLS; ANTIFUNGAL AGENTS; BREAST NEOPLASMS; CANDIDA ALBICANS; CELL LINE, TUMOR; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; COLONIC NEOPLASMS; FEMALE; HUMANS; LUNG NEOPLASMS; MACROLIDES; STREPTOMYCES;

EID: 84971294660     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2015.121     Document Type: Article

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