Biomechanics of articular cartilage

Basic Biomechanics of the Musculoskeletal System

Volumn , Issue , 2012, Pages 60-101

  Hung, Clark T ^a   Mow, Van C ^a  

^a Columbia University ^*  (United States)

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EID: 84971229058     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (188)

1. Ahmed, A.M., Burke, D.L. (1983). In vitro measurement of static pressure distribution in synovial joints-Part 1: Tibial surface of the knee. J Biomech Eng, 105, 216.
2. Akizuki, S., Mow, V.C., Muller, F., et al. (1986). Tensile properties of knee joint cartilage: 1. Influence of ionic condition, weight bearing, and fibrillation on the tensile modulus. J Orthop Res, 4, 379.
3. Albro, M.B., Chahine N.O., Li, R., et al. (2008). Dynamic loading of deformable porous media can induce active solute transport. J Biomech, 41(15): 3152-3157.
4. Altman, R.D., Tenebaum, J., Latta, L., et al. (1984). Biomechanical and biochemical properties of dog cartilage in experimentally induced osteoarthritis. Ann Rheum Dis, 43, 83.
5. Andriacchi, T.P., Natarajan, R.N., Hurwitz, D.E. (1997). Musculoskeletal dynamics, locomotion, and clinical application. In V.C. Mow, W.C. Hayes (Eds.). Basic Orthopaedic Biomechanics (2nd ed.). Philadelphia: Lippincott-Raven Publishers, 31-68.
6. Armstrong, C.G., Bahrani, A.S., Bardner, D L. (1979). In vitro measurement of articular cartilage deformations in the intact human hip joint under load. J Bone Joint Surg, 61A, 744.
7. Armstrong, C.G., Mow, V.C. (1980). Friction, lubrication and wear of synovial joints. In R. Owen, P. Goodfellow, P. Bullough (Eds.). Scientific Foundations of Orthopaedics and Traumatology. London: William Heinemann, 223-232.
8. Armstrong, C.G., Mow, V.C. (1982). Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content. J Bone Joint Surg, 64A, 88.
9. Ateshian, G.A. (1997). Theoretical formulation for boundary friction in articular cartilage. J Biomech Eng, 119, 81.
10. Ateshian, G.A. (2009). The role of interstitial fluid pressurization in articular cartilage lubrication. J Biomech, 42(9), 1163-1176.
11. Ateshian, G.A., Costa K.D., Hung, C.T. (2007). A theoretical analysis of water transport through chondrocytes. Biomech Model Mechanobiol, 6(1-2), 91-101.
12. Ateshian, G.A., Kwak, S.D., Soslowsky, L.J., et al. (1994). A new stereophotogrammetry method for determining in situ contact areas in diarthrodial joints: A comparison study. J Biomech, 27, 111.
13. Ateshian, G.A., Lai, W.M., Zhu, W.B., et al. (1995). An asymptotic solution for the contact of two biphasic cartilage layers. J Biomech, 27, 1347.
14. Ateshian, G.A., Wang, H. (1995). A theoretical solution for the frictionless rolling contact of cylindrical biphasic articular cartilage layers. J Biomech, 28, 1341.
15. Ateshian, G.A., Wang, H., Lai, W.M. (1998). The role of interstitial fluid in pressurization and surface porosities on the boundary friction of articular cartilage. J Tribol, 120, 241.
16. Ateshian, G.A., Warden, W.H., Kim, J.J., et al. (1997). Finite deformation biphasic material properties of bovine articular cartilage from confined compression experiments. J Biomech, 30, 1157.
17. Athanasiou, K.A., Rosenwasser, M.P., Buckwalter, J.A., et al. (1991). Interspecies comparison of in situ mechanical properties of distal femoral cartilage. J Orthop Res, 9, 330.
18. Bachrach, N.M., Mow, V.C., Guilak, F. (1998). Incompressibility of the solid matrix of articular cartilage under high hydrostatic pressure. J Biomech, 31, 445.
19. Bachrach, N.M., Valhmu, W.B., Stazzone, E J., et al. (1995). Changes in proteoglycan synthesis rates of chondrocytes in articular cartilage are associated with the time dependent changes in the mechanical environment. J Biomech, 28, 1561.
20. Basalo, I.M., Mauck, R.L., Kelly, T.A., et al. (2004). Cartilage interstitial fluid load support in unconfined compression following enzymatic digestion. J Biomech Eng, 126(6), 779-786.
21. Bateman, J F., Lamande, S.R., Ramshaw, J.A.M. (1996). Collagen superfamily. In W.D. Comper (Ed.): Extracellular Matrix (Vol. 2). Amsterdam, Netherlands: Harwood Academic Publishers, 2267.
22. Bollet, A.J., Nance, J.L. (1965). Biochemical findings in normal and osteoarthritic articular cartilage, II: Chondroitin sulfate concentration and chain length, and water and ash content. J Clin Invest, 45, 1170.
23. Bowden, F.P., Tabor, D. (1967). Friction and Lubrication. London, UK: Methuen.
24. Broom, N D., Silyn-Roberts, H. (1990). Collagen-collagen versus collagen-proteoglycan interactions in the determination of cartilage strength. Arthritis Rheum, 33, 1512.
25. Buckwalter, J.A., Kuettner, K.E., Thonar, E.J.-M.A. (1985). Agerelated changes in articular cartilage proteoglycans: Electron microscopic studies. J Orthop Res, 3, 251.
26. Bullough, P.G., Goodfellow, J. (1968). The significance of the fine structures of articular cartilage. J Bone Joint Surg, 50B, 852.
27. Bullough, P.G., Jagannath, A. (1983). The morphology of the calcification front in articular cartilage. J Bone Joint Surg, 65B, 72.
28. Buschmann, M. D., Gluzband, Y.A., Grodzinsky, A.J., et al. (1992). Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res, 10, 745.
29. Buschmann, M.D., Grodzinsky, A.J. (1995). A molecular model of proteoglycan-associated electrostatic forces in cartilage mechanics. J Biomech Eng, 117, 170.
30. Butler, D.L., Goldstein, S.A., Guilak, F. (2000). Functional tissue engineering: The role of biomechanics. J Biomech Eng, 122(6), 570-575.
31. Caligaris, M., Ateshian, G.A. (2008). Effects of sustained interstitial fluid pressurization under migrating contact area, and boundary lubrication by synovial fluid, on friction. Osteoarthritis Cartilage, 16(10), 1220-1227.
32. Clark, J. M. (1985). The organization of collagen in cryofractured rabbit articular cartilage: A scanning electron microscopy study. J Orthop Res, 3, 17.
33. Clarke, I C. (1971). Articular cartilage: A review and scanning electron microscope study-l. The interterritorial fibrillar architecture. J Bone Joint Surg, 53B, 732.
34. Donnan, F.G. (1924). The theory of membrane equilibria. Chem Rev, 1, 73.
35. Donohue, J.M., Buss, D., Oegema, T.R., et al. (1983). The effects of indirect blunt trauma on adult canine articular cartilage. J Bone Joint Surg, 65A, 948.
36. Dowson, D. (1966/1967). Modes of lubrication in human joints. Proc Inst Mech Eng, 181J, 45.
37. Dowson, D. (1990). Bio-tribology of natural and replacement joints. In V.C. Mow, A. Ratcliffe, S-L.Y. Woo (Eds.). Biomechanics of Diarthrodial Joints. New York: Springer-Verlag, 305-345.
38. Dunkelman, N.S., Zimber, M.P., LeBaron, R.G., et al. (1995). Cartilage production by rabbit articular chondrocytes on polyglycolic acid scaffolds in a closed bioreactor system. Biotech Bioeng, 46, 299-305.
39. Edwards, J. (1967). Physical characteristics of articular cartilage. Proc Inst Mech Eng, 181J, 16.
40. Elmore, S.M., Sokoloff, L., Norris, G., et al. (1963). Nature of "imperfect" elasticity of articular cartilage. J Applied Physiol, 18, 393.
41. Eyre, D.R. (1980). Collagen: Molecular diversity in the body's protein scaffold. Science, 207, 1315.
42. Fosang, A.J., Hardingham, T.E. (1996). Matrix proteoglycans. In W.D. Comper (Ed.) Extracellular Matrix (Vol. 2). Amsterdam, Netherlands: Harwood Academic Publishers, 200-229.
43. Frank, E.H., Grodzinsky, A.J. (1987a). Cartilage electromechanics- I. Electrokinetic transduction and effects of pH and ionic strength. J Biomech, 30, 615.
44. Frank, E.H., Grodzinsky, A.J. (1987b). Cartilage electromechanics- II. A continuum model of cartilage electrokinetics and correlation with experiments. J Biomech, 20, 629.
45. Freeman, M.A.R. (1975). The fatigue of cartilage in the pathogenesis of osteoarthrosis. Acta Orthop Scand, 46, 323.
46. Fung, Y.C. (1981). Quasi-linear viscoelasticity of soft tissues. In Biomechanics: Mechanical Properties of Living Tissues. New York: Springer-Verlag, 226.
47. Gardner, S.L., McGillivray, D.C. (1971). Living articular cartilage is not smooth. The structure of mammalian and avian joint surfaces demonstrated in vivo by immersion incident light microscopy. Ann Rheum Dis, 30, 3.
48. Garg, H.G., Swann, D.A. (1981). Age-related changes in the chemical composition of bovine articular cartilage. Biochem J, 193, 459.
49. Gleghorn, J.P., Jones, A.R., Flannery, C.R., et al. (2009). Boundary mode lubrication of articular cartilage by recombinant human lubricin. J Orthop Res, 27(6), 771-777.
50. Grad, S., Lee, C.R., Goma, K., et al. (2005). Surface motion upregulates superficial zone protein and hyaluronan production in chondrocyte-seeded three-dimensional scaffolds. Tissue Eng, 11(1-2), 249-256.
51. Gu, W.Y., Lai, W.M., Mow, V.C. (1993). Transport of fluid and ions through a porous-permeable charged-hydrated tissue, and streaming potential data on normal bovine articular cartilage. J Biomech, 26, 709.
52. Gu, W.Y., Lai, W.M., Mow, V.C. (1997). A triphasic analysis of negative osmotic flows through charged hydrated soft tissues. J Biomech, 30, 71.
53. Gu, W.Y., Lai, W.M., Mow, V.C. (1998). A mixture theory for charged hydrated soft tissues containing multi-electrolytes: Passive transport and swelling behaviors. J Biomech Eng, 102, 169.
54. Guilak, F., Ratcliffe, A., Lane, N., et al. (1994). Mechanical and biochemical changes in the superficial zone of articular cartilage in a canine model of osteoarthritis. J Orthop Res, 12, 474.
55. Guterl, C., Hung, C.T., Ateshian, G.A. (2010). Electrostatic and non-electrostatic contributions of proteoglycans to the compressive equilibrium modulus of bovine articular cartilage. J Biomech, 43(7), 1343-1350.
56. Hardingham, T.E., Beardmore-Garg, M., Dunham, D.G. (1987). Protein domain structure of the aggregating proteoglycan from cartilage. Trans Orthop Res Soc, 12, 61.
57. Hardingham, T.E., Muir, H. (1974). Hyaluronic acid in cartilage and proteoglycan aggregation. Biochem J, 139, 565.
58. Hascall, V.C. (1977). Interactions of cartilage proteoglycans with hyaluronic acid. J Supramol Struct, 7, 101.
59. Hayes, W.C., Bodine, A.J. (1978). Flow-independent viscoelastic properties of articular cartilage matrix. J Biomech, 11, 407.
60. Hayes, W.C., Mockros, L.F. (1971). Viscoelastic properties of human articular cartilage. J Appl Physiol 31, 562.
61. Hawking, S.W. (1988). A Brief History of Time: From the Big Bang to Black Holes. New York: Bantam Books.
62. Heinegard, D., Wieslander, J., Sheehan, J., et al. (1985). Separation and characterization of two populations of aggregating proteoglycans from cartilage. Biochem J, 225, 95.
63. Helminen, H.J., Kiviranta, I., Tammi, M., et al. (Eds.) (1987). Joint Loading: Biology and Health of Articular Structures. Bristol, UK: Wright and Sons, Publishers.
64. Hills, B.A. (1989). Oligolamellar lubrication of joints by surface active phospholipid. J Rheum, 1-6, 82-91.
65. Hirsch, C. (1944). The pathogenesis of chondromalacia of the patella. Acta Chir Scand, 83(Suppl), 1.
66. Hlavacek, M. (1995). The role of synovial fluid filtration by cartilage in lubrication of synovial joints: IV. Squeeze-film lubrication for axial symmetry under high loading conditions. J Biomech, 28, 1199.
67. Hodge, W.A., Fijan, R.S., Carlson, K., et al. (1986). Contact pressure in the human hip joint measured in vivo. Proc Natl Acad Sci U S A, 83, 2879.
68. Holmes, M.H., Lai, W.M., Mow, V.C. (1985). Singular perturbation analysis on the nonlinear, flow-dependent, compressive stress-relaxation behavior of articular cartilage. J Biomech Eng, 107, 206.
69. Hou, J.S., Mow, V.C., Lai, W.M., et al. (1992). An analysis of the squeeze-film lubrication mechanism for articular cartilage. J Biomech, 25, 247.
70. Huang, C.Y., Stankiewicz, A., Ateshian, G.A., et al. (2005). Anisotropy, inhomogeneity, and tension-compression nonlinearity of human glenohumeral cartilage in finite deformation. J Biomech, 38(4), 799-809.
71. Hultkrantz, W. (1898). Ueber die Spaltrichtungen der Gelenkknorpel. Verh Anat Ges, 12, 248.
72. Hung, C.T., Bian, L., Stoker, A.M., et al. (2009). Functional tissue engineering of articular cartilage using adult chondrocytes. In Transactions of the International Cartilage Repair Society, Miami, Florida, May 23-26, 2009, 8th World Congress of the International Cartilage Repair Society, 169.
73. Hung, C.T., Mauck, R.L., Wang, C.-C.B., et al. (2004). A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading. Ann Biomed Eng, 32(1), 35-49.
74. Hwang, J., Bae, W.C., Shieu, W., et al. (2008), Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis. Arthritis Rheum, 58(12), 3831-3842.
75. Jay, G.D., Torres, J.R., Rhee, D.K., et al. (2007). Association between friction and wear in diarthrodial joints lacking lubricin. Arthritis Rheum, 56(11), 3662-3669.
76. Katchalsky, A., Curran, P.F. (1975). Nonequilibrium Thermodynamics in Biophysics (4th ed.). Cambridge, MA: Harvard University Press.
77. Kelly, T.N., Ng, K.W., Wang, C.-C.B., et al. (2006). Spatial and temporal development of chondroctye-seeded agarose constructs in free-swelling and dynamically loaded cultures. J Biomech, 39(8), 1489-1497.
78. Kempson, G.E. (1979). Mechanical properties of articular cartilage. In M.A.R. Freeman (Ed.). Adult Articular Cartilage (2nd ed). Tunbridge Wells, UK: Pitman Medical, 333-414.
79. Kempson, G.E., Tuke, M.A., Dingle, J.T., et al. (1976). The effects of proteolytic enzymes on the mechanical properties of adult human articular cartilage. Biochem Biophys Acta, 428, 741.
80. Kim, Y.J., Sah, R.L., Grodzinsky, A.J., et al. (1994). Mechanical regulation of cartilage biosynthetic behavior: Physical stimuli. Arch Biochem Biophys, 311, 1.
81. Krishnan, R., Caligaris, M., Mauck, R.L., et al. (2004). Removal of the superficial zone of bovine articular cartilage does not increase its frictional coefficient. Osteoarthritis Cartilage, 12(12), 947-955.
82. Krishnan, R., Park, S., Eckstein, F., et al. (2003). Inhomogeneous cartilage properties enhance superficial interstitial fluid support and frictional properties, but do not provide a homogeneous state of stress. J Biomech Eng, 125(5), 569- 577.
83. Lai, W.M., Gu, W.Y., Mow, V.C. (1998). On the conditional equivalence of chemical loading and mechanical loading on articular cartilage. J Biomech, 31(12), 1181-1185.
84. Lai, W.M., Hou, J.S., Mow, V.C. (1991). A triphasic theory for the swelling and deformation behaviors of articular cartilage. J Biomech Eng, 113, 245.
85. Lai, W.M., Mow, V.C. (1978). Ultrafiltration of synovial fluid by cartilage. J Eng Mech Div ASCE, 104, 79.
86. Lai, W.M., Mow, V.C. (1980). Drag-induced compression of articular cartilage during a permeation experiment. Biorheology 17, 111.
87. Lakes, R., Saha, S. (1979). Cement line motion in bone. Science, 204, 501.
88. Lane, J.M., Weiss, C. (1975). Review of articular cartilage collagen research. Arthritis Rheum, 18, 553.
89. Lima, E.G., Bian, L., Ng, K.W., et al. (2007). The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-B3. Osteoarthritis Cartilage, 15(9), 1025-1033.
90. Linn, F.C. (1968). Lubrication of animal joints: 1. The mechanism. J Biomech, 1, 193.
91. Linn, F.C., Radin, E.L. (1968). Lubrication of animal joints: III. The effect of certain chemical alterations of the cartilage and lubricant. Arthritis Rheum, 11, 674.
92. Linn, F.C., Sokoloff, L. (1965). Movement and composition of interstitial fluid of cartilage. Arthritis Rheum, 8, 481.
93. Lipshitz, H., Etheredge, R., Glimcher, M.J. (1975). In vitro wear of articular cartilage: I. Hydroxyproline, hexosamine, and amino acid composition of bovine articular cartilage as a function of depth from the surface; hydroxyproline content of the lubricant and the wear debris as a measure of wear. J Bone Joint Surg, 57A, 527.
94. Lipshitz, H., Etheredge, R., Glimcher, M.J. (1976). Changes in the hexosamine content and swelling ratio of articular cartilage as functions of depth from the surface. J Bone Joint Surg, 58A, 1149.
95. Lipshitz, H., Glimcher, M.J. (1979). In vitro studies of the wear of articular cartilage. Wear, 52, 297.
96. Malcolm, L.L. (1976). An experimental investigation of the frictional and deformational responses of articular cartilage interfaces to static and dynamic loading. Doctoral thesis, University of California, San Diego.
97. Mankin, H.A., Thrasher, A.Z. (1975). Water content and binding in normal and osteoarthritic human cartilage. J Bone Joint Surg, 57A, 76.
98. Mansour, J.M., Mow, V.C. (1976). The permeability of articular cartilage under compressive strain and at high pressures. J Bone Joint Surg, 58A, 509.
99. Maroudas, A. (1966/1967). Hyaluronic acid films. Proc Inst Mech Eng London, 181J, 122.
100. Maroudas, A. (1968). Physicochemical properties of cartilage in light of ion-exchange theory. Biophys J, 8, 575.
101. Maroudas, A. (1975). Biophysical chemistry of cartilaginous tissues with special reference to solute and fluid transport. Biorheology, 12, 233.
102. Maroudas, A. (1976). Balance between swelling pressure and collagen tension in normal and degenerate cartilage.Nature, 260, 808.
103. Maroudas, A. (1979). Physicochemical properties of articular cartilage. In M.A.R. Freeman (Ed.), Adult Articular Cartilage (2nd ed). Tunbridge Wells, UK: Pitman Medical, 215-290.
104. Maroudas, A., Wachtel, E., Grushko, G., et al. (1991). The effect of osmotic and mechanical pressures on water partitioning in articular cartilage. Biochem Biophys Acta, 1073, 285.
105. Mauck, R.L., Hung, C.T., Ateshian, G.A. (2003a). Modeling of neutral solute transport in a dynamically loaded porous permeable gel: Implications for articular cartilage biosynthesis and tissue. J Biomech Eng, 125(5), 602-614.
106. Mauck, R.L., Nicoll, S.B., Seyhan, S.L., et al. (2003b). Synergistic effects of growth factors and dynamic loading for cartilage tissue engineering. Tissue Eng, 9(4), 597-611.
107. Mauck, R.L., Seyhan, S.L., Ateshian, G.A., et al. (2002). The influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyteseeded agarose hydrogels. Ann Biomed Eng, 30, 1046-1056.
108. Mauck, R.L., Soltz, M.A., Wang, C.C.-B., et al. (2000). Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng, 122, 252-260.
109. McCutchen, C.W. (1962). The frictional properties of animal joints.Wear, 5, 1.
110. McDevitt, C.A., Muir, H. (1976). Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog. J Bone Joint Surg, 58B, 94.
111. Meachim, G., Fergie, I.A. (1975). Morphological patterns of articular cartilage fibrillation. J Pathol, 115, 231.
112. Mow, V.C., Amoczky, S.P., Jackson, D.W. (1992). Knee Meniscus: Basic and Clinical Foundations. New York: Raven Press.
113. Mow, V.C., Ateshian, G.A. (1997). Lubrication and wear of diarthrodial joints. In V.C. Mow, W.C. Hayes (Eds.). Basic Biomechanics (2nd ed.). Philadelphia: Lippincott-Raven Publishers, 275-315.
114. Mow, V.C., Ateshian, G.A., Lai, W.M., et al. (1998). Effects of fixed charges on the stress-relaxation behavior of hydrated soft tissues in a confined compression problem. Int J Solids Struct, 35, 4945-4962.
115. Mow, V.C., Gibbs, M.C., Lai, W.M., et al. (1989a). Biphasic indentation of articular cartilage-Part II. A numerical algorithm and an experimental study. J Biomech, 22, 853.
116. Mow, V.C., Holmes, M.H., Lai, W.M. (1984). Fluid transport and mechanical properties of articular cartilage: A review. J Biomech, 17, 377.
117. Mow, V.C., Kuei, S.C., Lai, W.M., et al. (1980). Biphasic creep and stress relaxation of articular cartilage in compression: Theory and experiments. J Biomech Eng, 102, 73.
118. Mow, V.C., Lai, W.M., Redler, I. (1974). Some surface characteristics of articular cartilages. A scanning electron microscopy study and a theoretical model for the dynamic interaction of synovial fluid and articular cartilage. J Biomech, 7, 449.
119. Mow, V.C., Ratcliffe, A. (1997). Structure and function of articular cartilage and meniscus. In V.C. Mow, W.C. Hayes (Eds.). Basic Orthopaedic Biomechanics (2nd ed.). Philadelphia: Lippincott-Raven Publishers, 113-177.
120. Mow, V.C., Wang, C.C.-B. (1999). Some bioengineering considerations for tissue engineering of articular cartilage. Clin Orthop Rel Res, 367 (Suppl), S204-S223.
121. Mow, V.C., Wang, C.C., Hung, C.T. (1999). The extracellular matrix, interstitial fluid and ions as a mechanical signal transducer in articular cartilage. Osteoarthritis Cartilage, 7(1), 41-58.
122. Mow, V.C., Zhu, W.B., Lai, W.M., et al. (1989b). The influence of link protein stabilization on the viscoelastic properties of proteoglycan aggregates. Biochem Biophys Acta, 992, 201.
123. Muir, H. (1983). Proteoglycans as organizers of the extracellular matrix. Biochem Soc Trans, 11, 613.
124. Myers, E.R., Lai, W.M., Mow, V.C. (1984). A continuum theory and an experiment for the ion-induced swelling behavior cartilage. J Biomech Eng, 106(2), 151-158.
125. Newberry, W.N., Zukosky, D.K., Haut, R C. (1997). Subfracture insult to a knee joint causes alterations in the bone and in the functional stiffness of overlying cartilage. J Orthop Res, 15, 450.
126. Ng, L., Grodzinsky, A.J., Patwari, P., et al. (2003). Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol, 143(3), 242-257.
127. Onsager, L. (1931). Reciprocal relations in irreversible processes. I Phys Rev, 37, 405.
128. Oswald, E.S., Chao, P.H., Bulinski, J.C., et al. (2008). Dependence of zonal chondrocyte water transport properties on osmotic environment. Cell Mol Bioeng, 1(4), 339-348.
129. Park, S., Hung, C.T., Ateshian, G.A. (2004). Mechanical response of bovine articular cartilage under dynamic unconfined compression loading at physiological stress levels. Osteoarthritis Cartilage, 12(1), 65-73.
130. Park, S., Krishnan, R., Nicoll, S.B., et al. (2003). Cartilage interstitial fluid load support in unconfined compression. J Biomech, 36(12), 1785-1796.
131. Park S., Nicoll, S.B., Mauck, R.L., et al. (2008). Cartilage mechanical response under dynamic compression at physiological stress levels following collagenase digestion. Ann Biomed Eng, 36(3):425-434.
132. Paul, J.P. (1976). Force actions transmitted by joints in the human body. Proc Roy Soc Lond, 192B, 163.
133. Pazzano, D., Mercier, K.A., Moran, J.M., et al. (2000). Comparison of chondrogensis in static and perfused bioreactor culture. Biotechnol Prog, 16(5), 893-896.
134. Poole, A.R. (1986). Proteoglycans in health and disease: Structure and function. Biochem J, 236, 1.
135. Radin, E.L. (1976). Aetiology of osteoarthrosis. Clin Rheum Dis, 2, 509.
136. Radin, E.L., Paul, I.L. (1971). Response of joints to impact loading. I. In vitro wear. Arthritis Rheum, 14, 356.
137. Ratcliffe, A., Mow, V.C. (1996). Articular cartilage. In W.D. Comper (Ed.), Extracellular Matrix (Vol. 1). Amsterdam, Netherlands: Harwood Academic Publishers, 234-302.
138. Ratcliffe, A., Tyler, J., Hardingham, T.E. (1986). Articular cartilage culture with interleukin 1: Increased release of link protein, hyaluronate-binding region and other proteoglycan fragments. Biochem J, 238, 571.
139. Redler, I., Zimny, M.L. (1970). Scanning electron microscopy of normal and abnormal articular cartilage and synovium. J Bone Joint Surg, 52A, 1395.
140. Redler, I., Zimny, M.L., Mansell, J., et al. (1975). The ultrastructure and biomechanical significance of the tidemark of articular cartilage. Clin Orthop Rel Res, 112, 357.
141. Rosenberg, L., Choi, H.U., Tang, L.-H., et al. (1985). Isolation of dermatan sulfate proteoglycans from mature bovine articular cartilage. J Biol Chem, 260, 6304.
142. Rosenberg, L., Hellmann, W., Kleinschmidt, A.K. (1975). Electron microscopic studies of proteoglycan aggregates from bovine articular cartilage. J Biol Chem, 250, 1877.
143. Roth, V., Mow, V.C. (1980). The intrinsic tensile behavior of the matrix of bovine articular cartilage and its variation with age. J Bone Joint Surg, 62A, 1102.
144. Roughley, P.J., White, R.J. (1980). Age-related changes in the structure of the proteoglycan subunits from human articular cartilage. J Biol Chem, 255, 217.
145. Roughley, P.J., White, R.J., Santer, V. (1981). Comparison of proteoglycans extracted from high and low-weight-bearing human articular cartilage, with particular reference to sialic acid content. J Biol Chem, 256, 12699.
146. Schinagl, R.M., Gurskis, D., Chen, A.C., et al. (1997). Depthdependent confined compression modulus of full-thickness bovine articular cartilage. J Orthop Res, 15, 499.
147. Schinagl, R.M., Ting, M.K., Price, J.H., et al. (1996). Video microscopy to quantitate the inhomogeneous equilibrium strain within articular cartilage during confined compression. Ann Biomed Eng, 24, 500.
148. Schmidt, M.B., Mow, V.C., Chun, L.E., et al. (1990). Effects of proteoglycan extraction on the tensile behavior of articular cartilage. J Orthop Res, 8, 353.
149. Schmidt, T.A., Gastelum, N.S., Nguyen, Q.T., et al. (2007). Boundary lubrication of articular cartilage: Role of synovial fluid constituents. Arthritis Rheum, 56(3), 882-891.
150. Schneiderman, R., Keret, D., Maroudas, A. (1986). Effects of mechanical and osmotic pressure on the rate of glycosaminoglycan synthesis in adult femoral head cartilage: An in vitro study. J Orthop Res, 4, 393.
151. Schubert, M., Hamerman, D. (1968). A Primer on Connective Tissue Biochemistry. Philadelphia: Lea & Febiger.
152. Scott, J.E., Orford, C.R. (1981). Dermatan sulphate-rich proteoglycan associates with rat tail-tendon collagen at the d band in the gap region. Biochem J, 197, 213.
153. Seog, J., Dean D., Rolauffs, B., et al, C. (2005). Nanomechanics of opposing glycosaminoglycan macromolecules. J Biomech, 38(9), 1789-1797.
154. Setton, L.A., Gu, W.Y., Lai, W.M., et al. (1995). Predictions of the swelling induced pre-stress in articular cartilage. In A.P.S. Selvadurai (Ed.): Mechanics of Porous Media. Kluwer Academic Publishers. Dordrecht, Netherlands, 299-322.
155. Setton, L.A., Mow, V.C., Muller, F.J., et al. (1994). Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament. J Orthop Res, 12, 451.
156. Setton, L.A., Tohyama, H., Mow, V.C. (1998). Swelling and curling behavior of articular cartilage. J Biomech Eng, 120, 355.
157. Setton, L.A., Zhu, W.B., Mow, V.C. (1993). The biphasic poroviscoelastic behavior of articular cartilage in compression: Role of the surface zone. J Biomech, 26, 581.
158. Shen, Z.L., Dodge, M.R., Kahn, H., et al J. (2008). Stress-strain experiments on individual collagen fibrils. Biophys J, 95(8), 3956-3963.
159. Sokoloff, L. (1963). Elasticity of articular cartilage: Effect of ions and viscous solutions. Science, 141, 1055.
160. Soltz, M.A., Ateshian, G.A. (1998). Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression. J Biomech, Oct 31 (10), 927-934.
161. Stockwell, R.S. (1979). Biology of Cartilage Cells. Cambridge, UK: Cambridge University Press.
162. Sun, D.N., Gu, W.Y., Guo, X.E., et al. (1998). The influence of inhomogeneous fixed charge density on cartilage mechanoelectrochemical behaviors. Trans Orthop Res Soc, 23, 484.
163. Swann, D.A., Radin, E.L., Hendren, R.B. (1979). The lubrication of articular cartilage by synovial fluid glycoproteins. Arthritis Rheum, 22, 665.
164. Swann, D.A., Silver, F.H., Slayter, H.S., et al. (1985). The molecular structure and lubricating activity of lubricin from bovine and human synovial fluids. Biochem J, 225, 195.
165. Sweet, M.B.E., Thonar, E.J.-M.A., Marsh, J. (1979). Age-related changes in proteoglycan structure. Arch Biochem Biophys, 198, 439-448.
166. Thompson, R.C., Oegema, T.R., Lewis, J.L., et al. (1991). Osteoarthrotic changes after acute transarticular load. An animal model. J Bone Joint Surg, 73A, 990.
167. Thonar, E.J.-M.A., Bjornsson, S., Kuettner, K.E. (1986). Agerelated changes in cartilage proteoglycans. In K. Kuettner, R.S. Schleyerbach, V.C. Hascall (Eds.). Articular Cartilage Biochemistry. New York: Raven Press, 273-287.
168. Torzilli, P.A., Mow, V.C. (1976). On the fundamental fluid transport mechanisms through normal and pathologic cartilage during function. I. The formulation. J Biomech, 9(8), 541- 552.
169. Torzilli, P.A., Rose, D.E., Dethemers, S.A. (1982). Equilibrium water partition in articular cartilage. Biorheology, 19, 519.
170. Urban, J.P.G., McMullin, J.F. (1985). Swelling pressure of the intervertebral disc: Influence of collagen and proteoglycan content. Biorheology, 22, 145.
171. Valhmu, W.B., Stazzone, E.J., Bachrach, N.M., et al. (1998). Loadcontrolled compression of articular cartilage induces a transient stimulation of aggrecan gene expression. Arch Biochem Biophys, 353, 29.
172. Venn, M.F. (1978). Variation of chemical composition with age in human femoral head cartilage. Ann Rheum Dis, 37, 168.
173. Vunjak-Novakovic, G., Martin, I., Obradovic, B., et al. (1999). Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res, 17, 130-138.
174. Wada, T., Akizuki, S. (1987). An ultrastructural study of solid matrix in articular cartilage under uniaxial tensile stress. J Jpn Orthop Assoc, 61.
175. Walker, P.S., Dowson, D., Longfeild, M.D., et al. (1968). 'Boosted lubrication' in synovial joints by fluid entrapment and enrichment. Ann Rheum Dis, 27, 512.
176. Walker, P.S., Unsworth, A., Dowson, D., et al. (1970). Mode of aggregation of hyaluronic acid protein complex on the surface of articular cartilage. Ann Rheum Dis, 29, 591.
177. Wang, C.B., Mow, V.C. (1998). Inhomogeneity of aggregate modulus affects cartilage compressive stress-relaxation behavior. Trans Orthop Res Soc, 23(1), 481.
178. Wang, C.C., Chahine, N.O., Hung, C.T., et al. (2003) Optical determination of anisotropic material properties of bovine articular cartilage in compression. J Biomech, 36(3), 339-353.
179. Wang, C.C.-B., Deng, J.M., Ateshian, G.A., et al. (2002a). An automated approach for direct measurement of strain distributions within articular cartilage under unconfined compression. J Biomech Eng, 124, 557-567.
180. Wang, C C.-B., Guo, X.E., Sun, D., et al. (2002b). The functional environment of chondrocytes within cartilage subjected to compressive loading: Theoretical and experimental approach. Biorheology, 39(1-2), 39-45.
181. Weiss, C., Rosenberg, L., Helfet, A.J. (1968). An ultrastructural study of normal young adult human articular cartilage. J Bone Joint Surg, 50A, 663.
182. Williams, P.F., Powell, G.L., Laberge, M. (1993). Sliding friction analysis of phosphatidylcholine as a boundary lubricant for articular cartilage. Proc Inst Mech Eng H, 207, 59.
183. Woo, S.L.-Y., Mow, V.C., Lai, W.M. (1987). Biomechanical properties of articular cartilage. In Handbook of Bioengineering. New York: McGraw-Hill, 4.1-4.44.
184. Woo, S.L.Y., Levesay G.A., Runco, T.J., et al. (1997). Structure and function of tendons and ligaments. In V.C. Mow, W.C. Hayes (Eds.). Basic Orthopaedic Biomechanics (2nd ed.). Philadelphia: Lippincott-Raven Publishers, 209-251.
185. Zhu, W.B., Iatridis, J.C., Hlibczjk, V., et al. (1996). Determination of collagen-proteoglycan interactions in vitro. J Biomech, 29, 773.
186. Zhu, W.B., Lai, W.M., Mow, V.C. (1986). Intrinsic quasi-linear viscoelastic behavior of the extracellular matrix of cartilage. Trans Orthop Res Soc, 11, 407.
187. Zhu, W.B., Lai, W.M., Mow, V.C. (1991). The density and strength of proteoglycan-proteoglycan interaction sites in concentrated solutions. J Biomech, 24, 1007.
188. Zhu, W.B., Mow, V.C., Koob, T.J., et al. (1993). Viscoelastic shear properties of articular cartilage and the effects of glycosidase treatments. J Orthop Res, 11, 771.