ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan

Nature Communications

Volumn 7, Issue , 2016, Pages

  Gerin, Isabelle ^a   Ury, Benoît ^a   Breloy, Isabelle ^b   Bouchet Seraphin, Céline ^c   Bolsée, Jennifer ^a   Halbout, Mathias ^a   Graff, Julie ^a   Vertommen, Didier ^a   Muccioli, Giulio G ^d   Seta, Nathalie ^c   Cuisset, Jean Marie ^e   Dabaj, Ivana ^c   Quijano Roy, Susana ^c,f,g   Grahn, Ammi ^a,h   Van Schaftingen, Emile ^a   Bommer, Guido T ^a  

^a DE DUVE INSTITUTE   (Belgium)

^b UNIVERSITY OF COLOGNE   (Germany)

^c BICHAT HOSPITAL   (France)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f Centre de Référence des Maladies Neuromusculaires   (France)

^g LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^h UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DYSTROGLYCAN; CYTIDINE DIPHOSPHATE; FUKUTIN; FUKUTIN RELATED PROTEIN; ISOPRENOID; ISOPRENOID SYNTHASE DOMAIN CONTAINING PROTEIN; RIBITOL; RIBITOL PHOSPHATE; UNCLASSIFIED DRUG; CYTIDINE DIPHOSPHATE RIBITOL; DYSTROGLYCAN; FKRP PROTEIN, HUMAN; FKTN PROTEIN, HUMAN; ISPD PROTEIN, HUMAN; MEMBRANE PROTEIN; NUCLEOSIDE DIPHOSPHATE SUGAR; NUCLEOTIDYLTRANSFERASE; PROTEIN; RIBOSE;

ALCOHOL; CHEMICAL REACTION; ENZYME ACTIVITY; GENE EXPRESSION; MUSCLE; MUTATION; NERVOUS SYSTEM DISORDER; PHOSPHATE GROUP; PROTEIN;

ANIMAL CELL; ARTICLE; DIET SUPPLEMENTATION; DYSTROGLYCANOPATHY; ENZYME SYNTHESIS; FIBROBLAST; GENE MUTATION; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; MOUSE; NEUROMUSCULAR DISEASE; NONHUMAN; PROTEIN TRANSPORT; RAT; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; MALE; METABOLISM; SKELETAL MUSCLE CELL;

ANIMALS; DYSTROGLYCANS; GLYCOSYLATION; HEK293 CELLS; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MUSCLE FIBERS, SKELETAL; NUCLEOSIDE DIPHOSPHATE SUGARS; NUCLEOTIDYLTRANSFERASES; PROTEINS; RATS; RIBOSE;

EID: 84970998096     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11534     Document Type: Article

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