End-of-life care pathways for improving outcomes in caring for the dying

Cochrane Database of Systematic Reviews

Volumn 2016, Issue 2, 2016, Pages

  Chan, Raymond J ^a   Webster, Joan ^b   Bowers, Alison ^c  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^c The Park Centre for Mental health   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIA; BEREAVEMENT; CAREGIVER; CLINICAL PATHWAY; DISEASE SEVERITY; DYING; DYSPNEA; GRIEF; HEALTH CARE COST; HEALTH PRACTITIONER; HUMAN; NAUSEA; NURSING HOME; OUTCOME ASSESSMENT; PATIENT CARE; PATIENT SATISFACTION; PREVENTION; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; PSYCHOLOGY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SPIRITUAL CARE; SYSTEMATIC REVIEW; TERMINAL CARE; THERAPY EFFECT; TREATMENT OUTCOME; VOMITING; WELLBEING;

CRITICAL PATHWAYS; DYSPNEA; HUMANS; NAUSEA; PAIN MANAGEMENT; PREVENTION AND CONTROL; PSYCHOLOGY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TERMINAL CARE; TREATMENT OUTCOME; VOMITING;

EID: 84969924821     PISSN: 1469493X     EISSN: 13616137     Source Type: Journal    
DOI: 10.1002/14651858.CD008006.pub4     Document Type: Review

References (87)

1. Costantini M, Romoli V, Di Leo S, Beccaro M, Bono L, Pilastri P, et al. Liverpool Care Pathway for patients with cancer in hospital: a cluster randomised trial. Lancet 2014;383:226-37.
2. Bailey FA, Burgio KL, Woodby LL, Williams BR, Redden DT, Kovac SH, et al. Improving processes of hospital care during the last hours of life. Archives of Internal Medicine 2005;165(15):1722-7.
3. Bookbinder M, Blank A, Arney E, Wollner D, Lesage P, McHugh M, et al. Improving end-of-life care: development and pilot-test of a clinical pathway. Journal of Pain and Symptom Management 2005;29(6):529-43.
4. Chaplin D. Developing an end-of-life care pathway to improve nurses' bereavement care. Nursing Times 2009;105(1):20-1.
5. Costantini M, Pellergrini F, Di Leo S, Beccaro M, Rossi C, Glego G, et al. The Liverpool Care Pathway for cancer patients dying in hospital medical wards: a before-after cluster phase II trial of outcomes reported by family members. Palliative Medicine 2013 May 7 [Epub ahead of print].
6. Costantini M, Pellerini F, Di Leo S, Beccaro M, Rossi C, Flego G, et al. The Liverpool Care Pathway for cancer patients dying in hospital medical wards: a before-after cluster phase II trial of outcomes reported by family members. Palliative Medicine 2014;28(1):10-17.
7. Di Leo S, Bono L, Romoli V, West E, Ambrosio R, Gallucci M, et al. Implementation of the Liverpool Care Pathway (LCP) for the dying patient in the inpatient hospice setting: development and preliminary assessment of the Italian LCP Program. American Journal of Hospice and Palliative Care 2014;31(1):61-8.
8. Ellershaw J, Murphy D, Shea T, Foster A, Overill S. Developing an integrated care pathway for the dying patient. European Journal of Palliative Care 1997;4:203-8.
9. Ellershaw J, Smith C, Overill S, Walker SE, Aldridge J. Care of the dying: setting standards for symptom control in the last 48 hours of life. Journal of Pain and Symptom Management 2001;21(1):12-7.
10. Ellershaw J, Ward C. Care of the dying patient: the last hours or days of life. BMJ 2003;326(7379):30-4.
11. Ellershaw J. Care of the dying: what a difference an LCP makes!. Palliative Medicine 2007;21(5):365-8.
12. Fowell A, Finlay I, Johnstone R, Minto L. An integrated care pathway for the last two days of life: Wales-wide benchmarking in palliative care. International Journal of Palliative Nursing 2002;8(12):566-73.
13. Fowell A, Finlay I, Johnstone R, Minto L. An integrated care pathway for the last two days of life: a pathway for implementing a pathway. Journal of Integrated Care Pathways 2003;7(3):91-9.
14. Hardy JR, Haberecht J, Maresco-Pennisi D, Yates P. Audit of the care of the dying in a network of hospitals and institutions in Queensland. Internal Medicine Journal 2007;37(5):315-9.
15. Hockley J, Dewar B, Watson J. Promoting end-of-life care in nursing homes using an 'integrated care pathway for the last days of life'. Journal of Research in Nursing 2005;10(2):135-52.
16. Horey D, Street A, Sands A. Acceptability and feasibility of end-of-life care pathways in Australian residential aged care facilities. Medical Journal of Australia 2012;197(2):106-9.
17. Jack BA, Gambles M, Murphy D, Ellershaw JE. Nurses' perceptions of the Liverpool Care Pathway for the dying patient in the acute hospital setting. International Journal of Palliative Nursing 2003;9(9):375-81.
18. Johnson DC, Kassner CT, Kutner JS. Current use of guidelines, protocols, and care pathways for symptom management in hospice. The American Journal of Hospice & Palliative care 2004;21(1):51-7.
19. Luhrs CA, Meghani S, Homel P, Drayton M, O'Toole E, Paccione M, et al. Pilot of a pathway to improve the care of imminently dying oncology inpatients in a Veterans Affairs Medical Center. Journal of Pain and Symptom Management 2005;29(6):544-51.
20. Main J, Whittle C, Treml J, Woolley J, Main A. The development of an Integrated Care Pathway for all patients with advanced life-limiting illness - the Supportive Care Pathway. Journal of Nursing Management 2006;14(7):521-8.
21. Matthews K, Gambles M, Ellershaw JE, Brook L, Williams M, Hodgson A, et al. Developing the Liverpool Care Pathway for the dying child. Paediatric Nursing 2006;18(1):18-21.
22. Mellor F, Foley T, Connolly M, Mercer V, Spanswick M. Role of a clinical facilitator in introducing an integrated care pathway for the care of the dying. International Journal of Palliative Nursing 2004;10(10):497-501.
23. Mirando S, Davies PD, Lipp A. Introducing an integrated care pathway for the last days of life. Palliative Medicine 2005;19(1):33-9.
24. Neo PS, Poon MC, Peh TY, Ong SY, Koo WH, Santoso U, et al. Improvements in end-of-life care with a protocol-based pathway for cancer patients dying in a Singapore hospital. Annals of the Academy of Medicine Singapore 2012;41(11):489-93.
25. Okon TR, Evans JM, Gomez CF, Blackhall LJ. Palliative educational outcome with implementation of PEACE tool integrated clinical pathway. Journal of Palliative Medicine 2004;7(2):279-95.
26. Osterlind J, Hansebo G, Lantz G, Ternestedt BM. Pathways in end-of-life care for older people: care managers' reasoning. International Journal of Palliative Nursing 2008;14(9):420-5.
27. Peterson JL, Hartman HW. A pathway for patients who die within a week of hospice admission. International Journal of Palliative Nursing 2000;6(1):39-42.
28. Pooler J, McCrory F, Steadman Y, Westwell H, Peers S. Dying at home: a care pathway for the last days of life in a community setting. International Journal of Palliative Nursing 2003;9(6):258-64.
29. Rose V. Evidence Base End of Life Care for Dying Patients and their Families in the Acute Health Care Setting. North Coast Area Health Service, NSW Health 2006.
30. Taylor AJ, Randall C. Process mapping: enhancing the implementation of the Liverpool Care Pathway. International Journal of Palliative Nursing 2007;13(4):163-7.
31. Thompson-Hill J, Hookey C, Salt E, O'Neill T. The supportive care plan: a tool to improve communication in end-of-life care. International Journal of Palliative Nursing 2009;15(5):250-5.
32. Veerbeek L, van Zuylen L, Gambles M, Swart SJ, van der Heide A, van der Rijt CC, et al. Audit of the Liverpool Care Pathway for the dying patient in a Dutch cancer hospital. Journal of Palliative Care 2006;22(4):305-8.
33. Veerbeek L, van der Heide A, de Vogel-Voogt E, de Bakker R, van der Rijt CC, Swart SJ, et al. Using the LCP: bereaved relatives' assessments of communication and bereavement. The American Journal of Hospice & Palliative Care 2008;25(3):207-14.
34. Veerbeek L, van Zuylen L, Swart SJ, van der Maas PJ, de Vogel-Voogt E, van der Rijt CC, et al. The effect of the Liverpool Care Pathway for the dying: a multi-centre study. Palliative Medicine 2008;22(2):145-51.
35. Verhofstede R, Smets T, Cohen J, Costantini M, Van Den Noortgate N, Van Der Heide A, et al. Development of the care programme for the last days of life for older patients in acute geriatric hospital wards: a phase 0-1 study according to the Medical Research Council Framework. BMC Palliative Care 2015;14:24.
36. Verhofstede R, Smets T, Cohen J, Costantini M, Van Den Noortgate N, Deliens L. Improving end-of-life care in acute geriatric hospital wards using the Care Programme for the Last Days of Life: study protocol for a phase 3 cluster randomized controlled trial. BMC Geriatrics 2015;15:13.
37. Addington-Hall JM. Introduction. Research Methods in Palliative Care. New York: Oxford University Press, 2007.
38. Badger F, Thomas K, Clifford C. Raising standards for elderly people dying in care homes. European Journal of Palliative Care 2007;14(6):238-41.
39. Bruera E, Kuehn N, Miller M, Selmser P, Macmillan K. The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients. Journal of Palliative Care 1991;7:6-9.
40. Campbell H, Hotchikiss R, Bradshaw N, Proteous M. Integrated care pathways. BMJ 1998;316:133-7.
41. Centers for Disease Control and Prevention. International Classification of Diseases, Ninth Revision (ICD-9). http://www.cdc.gov/nchs/icd/icd9.htm 26 Jan 2016.
42. Chalmers TC, Celano P, Sacks HS, Smith H. Bias in treatment assignment in controlled clinical trials. New England Journal of Medicine 1983;309:1358-61.
43. Chan R, Webster J, Phillips J, Currow D. The withdrawal of the Liverpool Care Pathway in the United Kingdom: what are the implications for Australia?. Medical Journal of Australia 2014;200(10):573.
44. Chan R. Towards better end-of-life care : a major opportunity for nurses to contribute to the debate. International Journal of Nursing Studies 2014;51(3):355-6.
45. Cohen S, Mount B, Strobel M, Bui F. The McGill Quality of Life Questionnaire: a measure of quality of life appropriate for people with advanced disease. A preliminary study of validity and acceptability. Palliative Medicine 1995;9(3):207-19.
46. Costantini M, Beccaro M, Merlo F. The last three months of life of Italian cancer patient. Methods, sample characteristics and response rate of the Italian survey of the dying of cancer (ISDOC). Palliative Medicine 2005;19:628-38.
47. Currow, D. Evidence-based policy. Journal of Palliative Medicine 2011;14(7):803.
48. Currow D, Abernethy A. Lessons from the Liverpool Care Pathway-evidence is key. The Lancet 2014;383(9913):192-3.
49. Deeks JJ, Dinnes J, D'Amico R, Sowden AJ, Sakaovitch C, Song F, et al. Evaluating non-randomised intervention studies. Health Technology Assessment 2003;7(27):1-4.
50. Delvin K. Controversial 'death' pathway. The Daily Telegraph 13 October 2009.
51. Department of Health. End of life care strategy: promoting high quality care for all adults at the end of life. London: Department of Health, 2008.
52. Department of Health and Ageing. Supporting Australians to Live Well at the End of Life-National Palliative Care Strategy 2010. Canberra, Australia: Department of Health and Ageing, 2011.
53. Di Leo S, Romoli V, Higginson I, Bulli F, Fantini S, Sguazzotti E, et al. 'Less ticking the boxes, more providing support': A qualitative study on health professionals' concerns towards the Liverpool Care of the Dying Pathway. Pallitative Medicine 2015;29(6):529-37.
54. Ellershaw J, Wilkinson S. Care for the Dying: a Pathway to Excellence. Oxford: Oxford University Press, 2003.
55. Effective Practice and Organisation of Care Review Group. Data collection checklist, 2002. epoc.cochrane.org/sites/epoc.cochrane.org/files/uploads/datacollectionchecklist.pdf (accessed 12 November 2013).
56. Fowell A, Russell I, Johnstone R, Finlay I, Russell D. Cluster randomisation or randomised consent as an appropriate methodology for trials in palliative care: a feasibility study [ISRCTN60243484]. BMC Palliative Care 2004;3(1):1.
57. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2012]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
58. Karlawish JH. Conducting research that involves subjects at the end of life who are unable to give consent. Journal of Pain and Symptom Management 2003;25(4):S14-24.
59. Kawn J, Sandercock, Pater AG. In-hospital care pathways for stroke. Cochrane Database of Systematic Reviews 2004, Issue 4. [DOI: 10.1002/14651858.CD002924.pub2]
60. Lemmens L, van Zelm R, Vanhaecht K, Kerkkamp H. Systematic review: indicators to evaluate effectiveness of clinical pathways for gastrointestinal surgery. Journal of Evaluation in Clinical Practice 2008;14(5):880-7.
61. Lunney JR, Lynn J, Foley DJ, Lipson S, Guralnik JM. Patterns of functional decline at the end of life. JAMA 2003;2879(19):2387-92.
62. McConnell T, O'Halloran P, Porter S, Donnelly M. Systematic realist review of key factors affecting the successful implementation and sustainability of the Liverpool Care Pathway for the dying patient. Worldviews on Evidence-Based Nursing 2013;10(4):218-37.
63. Medical Research Council. A framework for development and evaluation of RCTs for complex interventions to improve health. Medical Research Council, 2000.
64. Mills M, Davies H, Macrae W. Care of dying patients in hospital. BMJ 1994;309:583-6.
65. Ministry of Health NZ. Resource and Capability Framework for Integrated Adult Palliative Care Services in New Zealand. Wellington: Ministry of Health NZ, 2013.
66. Mularski R, Dy S, Shugarman S, Wilkinson A, Lynn J, Shekelle P, et al. A systematic review of measures of end-of-life care and its outcomes. Health Services Research 2007;42(5):1848-70.
67. Neuberger J, Guthrie C, Aaronvitch D, Hameed K, Bonser T, Harries R, et al. More care, less pathway: a review of the Liverpool Care Pathway, 2013. www.gov.uk/government/uploads/system/uploads/attachment_data/file/212450/Liverpool_Care_Pathway.pdf.
68. Parry R, Seymour J, Whittaker B, Bird L, Cox K. Rapid evidence review: pathways focused on the dying phase in end of life care and their key components. National End of Life Care Programme, NHS, 2013.
69. Phillips J, Halcomb E, Davidson P. End-of-life care pathways in acute and hospice care: an integrative review. Journal of Pain and Symptom Management 2011;41(5):940-55.
70. Portenoy R, Thaler H, Kornblith A, McCarthy L, Friedlanderklar H, Sobel K, et al. The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. European Journal of Cancer 1994;30(9):1326-36.
71. The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
72. Reyna Y, Bennett M, Bruera E. Ethical and practical issues in designing and conducting clinical trials in palliative care. In: Addington-Hall J, Bruera E, Higginson I, Payne S editor(s). Research Methods in Palliative Care. Oxford: Oxford University Press, 2008.
73. Rotter T, Kugler J, Koch R, Gothe H, Twork S, van Oostrum JM, et al. A systematic review and meta-analysis of the effects of clinical pathways on length of stay, hospital costs, and patient outcomes. BMC Health Service Research 2008;8(1):265.
74. Sacks H, Chalmers TC, Smith JH. Randomized versus historical controls for clinical trials. American Journal of Medicine 1982;72:233-40.
75. Schultz KF, Altman DG, Moher D, Consort Group. Consort 2010 statement: Updated guidelines for reporting parallel group randomised trials. PLoS Medicine 2010;7(3):e1000251.
76. Smith R. More training needed following concerns about death pathway: cancer tsar. The Daily Telegraph 17 October 2009.
77. Steinhauser KE, Christakis NA, Clipp EC, McNeilly M, McIntyre L, Tulsky JA. Factors considered important at the end of life by patients, family, physicians and other care providers. JAMA 2000;284(19):2476-82.
78. Steinhauser KE, Christakis NA, Clipp EC, McNeilly M, Grambow S, Parker J, et al. Preparing for the end of life: preferences of patients, families, physicians, and other care providers. Journal of Pain and Symptom Management 2001;22(3):727-37.
79. Teno JM, Clarridge B, Casey V, Edgman-Levitan S, Fowler J. Validation of Toolkit After-Death Bereaved Family Member Interview. Journal of Pain and Symptom Management 2001;22(3):752-8.
80. Travis S, Bernard M, Dixon S, McAuley W, Loving G, McClanahan L. Obstacles to palliation and end-of-life care in a long-term care facility. The Gerontologist 2002;42(3):342-9.
81. United Nations. World Population Ageing 2013. United Nations, Department of Economic and Social Affairs, Population Division, 2013.
82. World Health Organization. WHO definition of palliative care. www.who.int/cancer/palliative/definition/en/ (accessed 12 November 2013).
83. World Health Organization. Palliative Care for Older People: better practices. Geneva: WHO, 2011.
84. World Health Organization and Cancer Research UK. World Cancer Factsheet. WHO and Cancer Research UK, 2012.
85. Zigmond A, Snaith R. The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica 1983;67(6):361-70.
86. Chan R, Webster J. End-of-life care pathways for improving outcomes in caring for the dying. Cochrane Database of Systematic Reviews 2010, Issue 1. [DOI: 10.1002/14651858.CD008006.pub2]
87. Chan R, Webster J. End-of-life care pathways for improving outcomes in caring for the dying. Cochrane Database of Systematic Reviews 2013, Issue 11. [DOI: 10.1002/14651858.CD008006.pub3]