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Volumn 12, Issue 6, 2016, Pages 1059-1060
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Lysosomal storage of heparan sulfate causes mitochondrial defects, altered autophagy, and neuronal death in the mouse model of mucopolysaccharidosis III type C
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Author keywords
acetyl CoA; glycosaminoglycans; heparan sulfate; knockout mouse model; lysosome; mucopolysaccharidosis; glucosaminide N acetyltransferase
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Indexed keywords
ACYLTRANSFERASE;
AMYLOID BETA PROTEIN;
CYTOCHROME C OXIDASE;
GLYCOGEN SYNTHASE KINASE 3BETA;
HEPARAN GLUCOSAMINIDE N ACETYLTRANSFERASE;
HEPARAN SULFATE;
LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1;
MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA;
MESSENGER RNA;
PHOSPHATIDYLETHANOLAMINE;
REACTIVE OXYGEN METABOLITE;
SUCCINATE DEHYDROGENASE (UBIQUINONE);
TAU PROTEIN;
TUMOR NECROSIS FACTOR ALPHA;
UBIDECARENONE;
UBIQUITIN;
UNCLASSIFIED DRUG;
ALZHEIMER DISEASE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ARTICLE;
ASTROCYTE;
AUTOPHAGOSOME;
AUTOPHAGY;
CELL VACUOLE;
CEREBELLUM;
CONTROLLED STUDY;
DISORDERS OF MITOCHONDRIAL FUNCTIONS;
ENZYME ACTIVITY;
EXOCYTOSIS;
GRAY MATTER;
HIPPOCAMPUS;
HOMOZYGOSITY;
IMMUNOHISTOCHEMISTRY;
LYSOSOME STORAGE DISEASE;
MICROGLIA;
MITOCHONDRION SWELLING;
MITOPHAGY;
MOUSE;
NERVE CELL NECROSIS;
NONHUMAN;
OXIDATIVE STRESS;
PROTEIN ACETYLATION;
PROTEIN EXPRESSION;
PROTEIN HYDROLYSIS;
PROTEIN PHOSPHORYLATION;
SANFILIPPO SYNDROME;
SOMATOSENSORY CORTEX;
URINE RETENTION;
WHITE MATTER;
ANIMAL;
BRAIN;
CELL DEATH;
DISEASE MODEL;
HUMAN;
KNOCKOUT MOUSE;
LYSOSOME;
METABOLISM;
MITOCHONDRION;
NERVE CELL;
PATHOLOGY;
ANIMALS;
AUTOPHAGY;
BRAIN;
CELL DEATH;
DISEASE MODELS, ANIMAL;
HEPARITIN SULFATE;
HUMANS;
LYSOSOMES;
MICE;
MICE, KNOCKOUT;
MITOCHONDRIA;
MUCOPOLYSACCHARIDOSIS III;
NEURONS;
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EID: 84969856768
PISSN: 15548627
EISSN: 15548635
Source Type: Journal
DOI: 10.1080/15548627.2015.1046671 Document Type: Article |
Times cited : (42)
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References (0)
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