MRI texture features as biomarkers to predict MGMT methylation status in glioblastomas

Medical Physics

Volumn 43, Issue 6, 2016, Pages 2835-2844

  Korfiatis, Panagiotis ^a   Kline, Timothy L ^a   Coufalova, Lucie ^b   Lachance, Daniel H ^c   Parney, Ian F ^a   Carter, Rickey E ^a   Buckner, Jan C ^a   Erickson, Bradley J ^a  

^a MAYO CLINIC   (United States)

^b CHARLES UNIVERSITY   (Czech Republic)

^c ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

Author keywords

glioblastoma multiforme; imaging biomarkers; MGMT; MRI; random forest; support vector machines

Indexed keywords

ALKYLATION; BIOMARKERS; DECISION TREES; FORECASTING; METHYLATION; SUPPORT VECTOR MACHINES; TUMORS;

GLIOBLASTOMA MULTIFORME; GLIOBLASTOMAS; IMAGING BIOMARKERS; METHYLGUANINE METHYLTRANSFERASE; METHYLTRANSFERASES; RANDOM FORESTS; RECEIVER OPERATING CHARACTERISTIC CURVES; RESEARCH FOCUS; SUPPORT VECTORS MACHINE; TEXTURE FEATURES;

MAGNETIC RESONANCE IMAGING;

METHYLGUANINE METHYLTRANSFERASE; METHYLTRANSFERASE; UNCLASSIFIED DRUG; DNA LIGASE; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; ENTROPY; GLIOBLASTOMA; HUMAN; MAJOR CLINICAL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PROTEIN METHYLATION; RANDOM FOREST; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SUPPORT VECTOR MACHINE; BRAIN; BRAIN NEOPLASMS; DIAGNOSTIC IMAGING; DNA METHYLATION; GENETICS; PROCEDURES; PROMOTER REGION;

BIOMARKERS, TUMOR; BRAIN; BRAIN NEOPLASMS; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; GLIOBLASTOMA; HUMANS; MAGNETIC RESONANCE IMAGING; PROMOTER REGIONS, GENETIC; RETROSPECTIVE STUDIES; ROC CURVE; SUPPORT VECTOR MACHINE; TUMOR SUPPRESSOR PROTEINS;

EID: 84969855998     PISSN: 00942405     EISSN: 24734209     Source Type: Journal    
DOI: 10.1118/1.4948668     Document Type: Article

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