-
2
-
-
44849083256
-
What determines the molecular composition of abnormal protein aggregates in neurodegenerative disease?
-
Armstrong R.A., Lantos P.L., Cairns N.J. What determines the molecular composition of abnormal protein aggregates in neurodegenerative disease?. Neuropathology 2008, 28:351-365.
-
(2008)
Neuropathology
, vol.28
, pp. 351-365
-
-
Armstrong, R.A.1
Lantos, P.L.2
Cairns, N.J.3
-
3
-
-
0035997249
-
Senile plaque composition and posttranslational modification of amyloid-β peptide and associated proteins
-
Atwood C.S., Martins R.N., Smith M.A., Perry G. Senile plaque composition and posttranslational modification of amyloid-β peptide and associated proteins. Peptides 2002, 23:1343-1350.
-
(2002)
Peptides
, vol.23
, pp. 1343-1350
-
-
Atwood, C.S.1
Martins, R.N.2
Smith, M.A.3
Perry, G.4
-
5
-
-
84863504256
-
Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease
-
Holtzman D.M., Herz J., Bu G. Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb Perspect Biol 2012, 2:a006312.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.2
, pp. a006312
-
-
Holtzman, D.M.1
Herz, J.2
Bu, G.3
-
6
-
-
77953286012
-
Aβ-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease
-
Huang Y. Aβ-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease. Trends Mol Med 2010, 16:287-294.
-
(2010)
Trends Mol Med
, vol.16
, pp. 287-294
-
-
Huang, Y.1
-
7
-
-
0026597063
-
Alzheimer's disease: the amyloid cascade hypothesis
-
Hardy J.A., Higgins G.A. Alzheimer's disease: the amyloid cascade hypothesis. Science 1992, 256:184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
8
-
-
77956203927
-
Is Alzheimer's disease a disorder of mitochondria-associated membranes?
-
Schon E.A., Area-Gomez E. Is Alzheimer's disease a disorder of mitochondria-associated membranes?. J Alzheimers Dis 2010, 20:S281-S292.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. S281-S292
-
-
Schon, E.A.1
Area-Gomez, E.2
-
9
-
-
84875599536
-
Mitochondria-associated E.R. membranes in Alzheimer disease
-
Schon E.A., Area-Gomez E. Mitochondria-associated E.R. membranes in Alzheimer disease. Mol Cell Neurosci 2013, 55:26-36.
-
(2013)
Mol Cell Neurosci
, vol.55
, pp. 26-36
-
-
Schon, E.A.1
Area-Gomez, E.2
-
10
-
-
58149220667
-
Cholesterol in Alzheimer's disease: unresolved questions
-
Stefani M., Liguri G. Cholesterol in Alzheimer's disease: unresolved questions. Curr Alzheimer Res 2009, 6:15-29.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 15-29
-
-
Stefani, M.1
Liguri, G.2
-
11
-
-
76849108962
-
Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease
-
Fraser T., Tayler H., Love S. Fatty acid composition of frontal, temporal and parietal neocortex in the normal human brain and in Alzheimer's disease. Neurochem Res 2010, 35:503-513.
-
(2010)
Neurochem Res
, vol.35
, pp. 503-513
-
-
Fraser, T.1
Tayler, H.2
Love, S.3
-
12
-
-
0023737618
-
Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type?
-
Hoyer S., Oesterreich K., Wagner O. Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type?. J Neurol 1988, 235:143-148.
-
(1988)
J Neurol
, vol.235
, pp. 143-148
-
-
Hoyer, S.1
Oesterreich, K.2
Wagner, O.3
-
13
-
-
67650072530
-
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
-
Liu F., Shi J., Tanimukai H., Gu J., Gu J., Grundke-Iqbal I., Iqbal K., Gong C.X. Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain 2009, 132:1820-1832.
-
(2009)
Brain
, vol.132
, pp. 1820-1832
-
-
Liu, F.1
Shi, J.2
Tanimukai, H.3
Gu, J.4
Gu, J.5
Grundke-Iqbal, I.6
Iqbal, K.7
Gong, C.X.8
-
14
-
-
0034849057
-
Brain membrane phospholipid alterations in Alzheimer's disease
-
Pettegrew J.W., Panchalingam K., Hamilton R.L., McClure R.J. Brain membrane phospholipid alterations in Alzheimer's disease. Neurochem Res 2001, 26:771-782.
-
(2001)
Neurochem Res
, vol.26
, pp. 771-782
-
-
Pettegrew, J.W.1
Panchalingam, K.2
Hamilton, R.L.3
McClure, R.J.4
-
15
-
-
50249135503
-
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
-
Bezprozvanny I., Mattson M.P. Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci 2008, 31:454-463.
-
(2008)
Trends Neurosci
, vol.31
, pp. 454-463
-
-
Bezprozvanny, I.1
Mattson, M.P.2
-
16
-
-
64349099993
-
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
-
Wang X., Su B., Zheng L., Perry G., Smith M.A., Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem 2009, 109:153-159.
-
(2009)
J Neurochem
, vol.109
, pp. 153-159
-
-
Wang, X.1
Su, B.2
Zheng, L.3
Perry, G.4
Smith, M.A.5
Zhu, X.6
-
17
-
-
84927758518
-
Mitochondrial genetics and disease
-
Area-Gomez E., Schon E.A. Mitochondrial genetics and disease. J Child Neurol 2014, 29:1208-1215.
-
(2014)
J Child Neurol
, vol.29
, pp. 1208-1215
-
-
Area-Gomez, E.1
Schon, E.A.2
-
18
-
-
33749022800
-
Structural and functional features and significance of the physical linkage between ER and mitochondria
-
Csordas G., Renken C., Varnai P., Walter L., Weaver D., Buttle K.F., Balla T., Mannella C.A., Hajnoczky G. Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol 2006, 174:915-921.
-
(2006)
J Cell Biol
, vol.174
, pp. 915-921
-
-
Csordas, G.1
Renken, C.2
Varnai, P.3
Walter, L.4
Weaver, D.5
Buttle, K.F.6
Balla, T.7
Mannella, C.A.8
Hajnoczky, G.9
-
19
-
-
59449097391
-
MAM: more than just a housekeeper
-
Hayashi T., Rizzuto R., Hajnoczky G., Su T.P. MAM: more than just a housekeeper. Trends Cell Biol 2009, 19:81-88.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 81-88
-
-
Hayashi, T.1
Rizzuto, R.2
Hajnoczky, G.3
Su, T.P.4
-
20
-
-
84871726622
-
Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM)
-
Raturi A., Simmen T. Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM). Biochim Biophys Acta 2013, 1833:213-224.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 213-224
-
-
Raturi, A.1
Simmen, T.2
-
21
-
-
0027973135
-
A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins
-
Rusinol A.E., Cui Z., Chen M.H., Vance J.E. A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins. J Biol Chem 1994, 269:27494-27502.
-
(1994)
J Biol Chem
, vol.269
, pp. 27494-27502
-
-
Rusinol, A.E.1
Cui, Z.2
Chen, M.H.3
Vance, J.E.4
-
22
-
-
0031552936
-
Phosphatidylethanolamine N-methyltransferase from liver
-
Vance D.E., Walkey C.J., Cui Z. Phosphatidylethanolamine N-methyltransferase from liver. Biochim Biophys Acta 1997, 1348:142-150.
-
(1997)
Biochim Biophys Acta
, vol.1348
, pp. 142-150
-
-
Vance, D.E.1
Walkey, C.J.2
Cui, Z.3
-
23
-
-
0034602158
-
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes
-
Stone S.J., Vance J.E. Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes. J Biol Chem 2000, 275:34534-34540.
-
(2000)
J Biol Chem
, vol.275
, pp. 34534-34540
-
-
Stone, S.J.1
Vance, J.E.2
-
24
-
-
84921929741
-
Mitochondria-associated endoplasmic reticulum membrane (MAM) regulates steroidogenic activity via steroidogenic acute regulatory protein (StAR)-voltage-dependent anion channel 2 (VDAC2) interaction
-
Prasad M., Kaur J., Pawlak K.J., Bose M., Whittal R.M., Bose H.S. Mitochondria-associated endoplasmic reticulum membrane (MAM) regulates steroidogenic activity via steroidogenic acute regulatory protein (StAR)-voltage-dependent anion channel 2 (VDAC2) interaction. J Biol Chem 2015, 290:2604-2616.
-
(2015)
J Biol Chem
, vol.290
, pp. 2604-2616
-
-
Prasad, M.1
Kaur, J.2
Pawlak, K.J.3
Bose, M.4
Whittal, R.M.5
Bose, H.S.6
-
25
-
-
28844453210
-
2+ signals into mitochondria
-
2+ signals into mitochondria. J Biol Chem 2005, 280:40892-40900.
-
(2005)
J Biol Chem
, vol.280
, pp. 40892-40900
-
-
Mendes, C.C.1
Gomes, D.A.2
Thompson, M.3
Souto, N.C.4
Goes, T.S.5
Goes, A.M.6
Rodrigues, M.A.7
Gomez, M.V.8
Nathanson, M.H.9
Leite, M.F.10
-
26
-
-
33845692166
-
2+ channels
-
2+ channels. J Cell Biol 2006, 175:901-911.
-
(2006)
J Cell Biol
, vol.175
, pp. 901-911
-
-
Szabadkai, G.1
Bianchi, K.2
Varnai, P.3
De Stefani, D.4
Wieckowski, M.R.5
Cavagna, D.6
Nagy, A.I.7
Balla, T.8
Rizzuto, R.9
-
27
-
-
34547117903
-
Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts
-
Jia W., Moulson C.L., Pei Z., Miner J.H., Watkins P.A. Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts. J Biol Chem 2007, 282:20573-20583.
-
(2007)
J Biol Chem
, vol.282
, pp. 20573-20583
-
-
Jia, W.1
Moulson, C.L.2
Pei, Z.3
Miner, J.H.4
Watkins, P.A.5
-
28
-
-
80054844842
-
ER tubules mark sites of mitochondrial division
-
Friedman J.R., Lackner L.L., West M., DiBenedetto J.R., Nunnari J., Voeltz G.K. ER tubules mark sites of mitochondrial division. Science 2011, 334:358-362.
-
(2011)
Science
, vol.334
, pp. 358-362
-
-
Friedman, J.R.1
Lackner, L.L.2
West, M.3
DiBenedetto, J.R.4
Nunnari, J.5
Voeltz, G.K.6
-
29
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito O.M., Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008, 456:605-610.
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
de Brito, O.M.1
Scorrano, L.2
-
30
-
-
20144385980
-
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
-
Simmen T., Aslan J.E., Blagoveshchenskaya A.D., Thomas L., Wan L., Xiang Y., Feliciangeli S.F., Hung C.H., Crump C.M., Thomas G. PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. EMBO J 2005, 24:717-729.
-
(2005)
EMBO J
, vol.24
, pp. 717-729
-
-
Simmen, T.1
Aslan, J.E.2
Blagoveshchenskaya, A.D.3
Thomas, L.4
Wan, L.5
Xiang, Y.6
Feliciangeli, S.F.7
Hung, C.H.8
Crump, C.M.9
Thomas, G.10
-
31
-
-
73649098791
-
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria
-
Area-Gomez E., de Groof A.J., Boldogh I., Bird T.D., Gibson G.E., Koehler C.M., Yu W.H., Duff K.E., Yaffe M.P., Pon L.A., et al. Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol 2009, 175:1810-1816.
-
(2009)
Am J Pathol
, vol.175
, pp. 1810-1816
-
-
Area-Gomez, E.1
de Groof, A.J.2
Boldogh, I.3
Bird, T.D.4
Gibson, G.E.5
Koehler, C.M.6
Yu, W.H.7
Duff, K.E.8
Yaffe, M.P.9
Pon, L.A.10
-
32
-
-
84892449716
-
Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease
-
Newman M., Wilson L., Verdile G., Lim A., Khan I., Moussavi Nik S.H., Pursglove S., Chapman G., Martins R.N., Lardelli M. Differential, dominant activation and inhibition of Notch signalling and APP cleavage by truncations of PSEN1 in human disease. Hum Mol Genet 2014, 23:602-617.
-
(2014)
Hum Mol Genet
, vol.23
, pp. 602-617
-
-
Newman, M.1
Wilson, L.2
Verdile, G.3
Lim, A.4
Khan, I.5
Moussavi Nik, S.H.6
Pursglove, S.7
Chapman, G.8
Martins, R.N.9
Lardelli, M.10
-
33
-
-
84911899819
-
Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes
-
Schreiner B., Hedskog L., Wiehager B., Ankarcrona M. Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes. J Alzheimers Dis 2015, 43:369-374.
-
(2015)
J Alzheimers Dis
, vol.43
, pp. 369-374
-
-
Schreiner, B.1
Hedskog, L.2
Wiehager, B.3
Ankarcrona, M.4
-
34
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
Du H., Guo L., Fang F., Chen D., Sosunov A.A., McKhann G.M., Yan Y., Wang C., Zhang H., Molkentin J.D., et al. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med 2008, 14:1097-1105.
-
(2008)
Nat Med
, vol.14
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
Yan, Y.7
Wang, C.8
Zhang, H.9
Molkentin, J.D.10
-
35
-
-
19944373389
-
Nicastrin, presenilin, APH-1, and PEN-2 form active γ-secretase complexes in mitochondria
-
Hansson C.A., Frykman S., Farmery M.R., Tjernberg L.O., Nilsberth C., Pursglove S.E., Ito A., Winblad B., Cowburn R.F., Thyberg J., et al. Nicastrin, presenilin, APH-1, and PEN-2 form active γ-secretase complexes in mitochondria. J Biol Chem 2004, 279:51654-51660.
-
(2004)
J Biol Chem
, vol.279
, pp. 51654-51660
-
-
Hansson, C.A.1
Frykman, S.2
Farmery, M.R.3
Tjernberg, L.O.4
Nilsberth, C.5
Pursglove, S.E.6
Ito, A.7
Winblad, B.8
Cowburn, R.F.9
Thyberg, J.10
-
36
-
-
84868524156
-
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
-
Area-Gomez E., Del Carmen Lara Castillo M., Tambini M.D., Guardia-Laguarta C., de Groof A.J.C., Madra M., Ikenouchi J., Umeda M., Bird T.D., Sturley S.L., et al. Upregulated function of mitochondria-associated ER membranes in Alzheimer disease. EMBO J 2012, 31:4106-4123.
-
(2012)
EMBO J
, vol.31
, pp. 4106-4123
-
-
Area-Gomez, E.1
Del Carmen Lara Castillo, M.2
Tambini, M.D.3
Guardia-Laguarta, C.4
de Groof, A.J.C.5
Madra, M.6
Ikenouchi, J.7
Umeda, M.8
Bird, T.D.9
Sturley, S.L.10
-
37
-
-
77950284301
-
Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction
-
Hayashi T., Fujimoto M. Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction. Mol Pharmacol 2010, 77:517-528.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 517-528
-
-
Hayashi, T.1
Fujimoto, M.2
-
38
-
-
7244258941
-
Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes
-
Vetrivel K.S., Cheng H., Lin W., Sakurai T., Li T., Nukina N., Wong P.C., Xu H., Thinakaran G. Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes. J Biol Chem 2004, 279:44945-44954.
-
(2004)
J Biol Chem
, vol.279
, pp. 44945-44954
-
-
Vetrivel, K.S.1
Cheng, H.2
Lin, W.3
Sakurai, T.4
Li, T.5
Nukina, N.6
Wong, P.C.7
Xu, H.8
Thinakaran, G.9
-
39
-
-
18344380083
-
A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
-
Marambaud P., Shioi J., Serban G., Georgakopoulos A., Sarner S., Nagy V., Baki L., Wen P., Efthimiopoulos S., Shao Z., et al. A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J 2002, 21:1948-1956.
-
(2002)
EMBO J
, vol.21
, pp. 1948-1956
-
-
Marambaud, P.1
Shioi, J.2
Serban, G.3
Georgakopoulos, A.4
Sarner, S.5
Nagy, V.6
Baki, L.7
Wen, P.8
Efthimiopoulos, S.9
Shao, Z.10
-
40
-
-
77954301751
-
Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface
-
Csordas G., Varnai P., Golenar T., Roy S., Purkins G., Schneider T.G., Balla T., Hajnoczky G. Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface. Mol Cell 2010, 39:121-132.
-
(2010)
Mol Cell
, vol.39
, pp. 121-132
-
-
Csordas, G.1
Varnai, P.2
Golenar, T.3
Roy, S.4
Purkins, G.5
Schneider, T.G.6
Balla, T.7
Hajnoczky, G.8
-
41
-
-
80053175932
-
Calcium signaling around mitochondria associated membranes (MAMs)
-
Patergnani S., Suski J.M., Agnoletto C., Bononi A., Bonora M., De Marchi E., Giorgi C., Marchi S., Missiroli S., Poletti F., et al. Calcium signaling around mitochondria associated membranes (MAMs). Cell Commun Signal 2011, 9:19.
-
(2011)
Cell Commun Signal
, vol.9
, pp. 19
-
-
Patergnani, S.1
Suski, J.M.2
Agnoletto, C.3
Bononi, A.4
Bonora, M.5
De Marchi, E.6
Giorgi, C.7
Marchi, S.8
Missiroli, S.9
Poletti, F.10
-
42
-
-
84930198272
-
2+ dysregulation in the endoplasmic reticulum related to Alzheimer's disease: a review on experimental progress and computational modeling
-
2+ dysregulation in the endoplasmic reticulum related to Alzheimer's disease: a review on experimental progress and computational modeling. Biosystems 2015, 134:1-15.
-
(2015)
Biosystems
, vol.134
, pp. 1-15
-
-
Liang, J.1
Kulasiri, D.2
Samarasinghe, S.3
-
43
-
-
77953634580
-
ER calcium and Alzheimer's disease: in a state of flux
-
Mattson M.P. ER calcium and Alzheimer's disease: in a state of flux. Sci Signal 2010, 3:pe10.
-
(2010)
Sci Signal
, vol.3
, pp. pe10
-
-
Mattson, M.P.1
-
44
-
-
77956220629
-
Neuronal calcium signaling, mitochondrial dysfunction, and Alzheimer's disease
-
Supnet C., Bezprozvanny I. Neuronal calcium signaling, mitochondrial dysfunction, and Alzheimer's disease. J Alzheimers Dis 2010, 20(Suppl 2):S487-S498.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. S487-S498
-
-
Supnet, C.1
Bezprozvanny, I.2
-
45
-
-
0031470172
-
Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation
-
Gibson G.E., Vestling M., Zhang H., Szolosi S., Alkon D., Lannfelt L., Gandy S., Cowburn R.F. Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation. Neurobiol Aging 1997, 18:573-580.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 573-580
-
-
Gibson, G.E.1
Vestling, M.2
Zhang, H.3
Szolosi, S.4
Alkon, D.5
Lannfelt, L.6
Gandy, S.7
Cowburn, R.F.8
-
46
-
-
0343050763
-
Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors
-
Peterson C., Goldman J.E. Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors. Proc Natl Acad Sci U S A 1986, 83:2758-2762.
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 2758-2762
-
-
Peterson, C.1
Goldman, J.E.2
-
47
-
-
0023191781
-
Altered metabolic properties of cultured skin fibroblasts in Alzheimer's disease
-
Sims N.R., Finegan J.M., Blass J.P. Altered metabolic properties of cultured skin fibroblasts in Alzheimer's disease. Ann Neurol 1987, 21:451-457.
-
(1987)
Ann Neurol
, vol.21
, pp. 451-457
-
-
Sims, N.R.1
Finegan, J.M.2
Blass, J.P.3
-
48
-
-
84897463426
-
Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice
-
Sun S., Zhang H., Liu J., Popugaeva E., Xu N.-J., Feske S., White C.L., Bezprozvanny I. Reduced synaptic STIM2 expression and impaired store-operated calcium entry cause destabilization of mature spines in mutant presenilin mice. Neuron 2014, 82:79-93.
-
(2014)
Neuron
, vol.82
, pp. 79-93
-
-
Sun, S.1
Zhang, H.2
Liu, J.3
Popugaeva, E.4
Xu, N.-J.5
Feske, S.6
White, C.L.7
Bezprozvanny, I.8
-
49
-
-
64249133725
-
S-nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury
-
Cho D.-H., Nakamura T., Fang J., Cieplak P., Godzik A., Gu Z., Lipton S.A. S-nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury. Science 2009, 324:102-105.
-
(2009)
Science
, vol.324
, pp. 102-105
-
-
Cho, D.-H.1
Nakamura, T.2
Fang, J.3
Cieplak, P.4
Godzik, A.5
Gu, Z.6
Lipton, S.A.7
-
50
-
-
70449435581
-
Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease
-
Ferrer I. Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease. J Bioenerg Biomembr 2009, 41:425-431.
-
(2009)
J Bioenerg Biomembr
, vol.41
, pp. 425-431
-
-
Ferrer, I.1
-
51
-
-
10244255083
-
Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases
-
Gibson G.E., Huang H.-M. Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases. J Bioenerg Biomembr 2004, 36:335-340.
-
(2004)
J Bioenerg Biomembr
, vol.36
, pp. 335-340
-
-
Gibson, G.E.1
Huang, H.-M.2
-
52
-
-
84884289093
-
Axonal transport and mitochondrial dysfunction in Alzheimer's disease
-
Riemer J., Kins S. Axonal transport and mitochondrial dysfunction in Alzheimer's disease. Neurodegener Dis 2013, 12:111-124.
-
(2013)
Neurodegener Dis
, vol.12
, pp. 111-124
-
-
Riemer, J.1
Kins, S.2
-
53
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
-
Stokin G.B., Lillo C., Falzone T.L., Brusch R.G., Rockenstein E., Mount S.L., Raman R., Davies P., Masliah E., Williams D.S., et al. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science 2005, 307:1282-1288.
-
(2005)
Science
, vol.307
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
Brusch, R.G.4
Rockenstein, E.5
Mount, S.L.6
Raman, R.7
Davies, P.8
Masliah, E.9
Williams, D.S.10
-
54
-
-
58049218922
-
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
Wang X., Su B., Siedlak S.L., Moreira P.I., Fujioka H., Wang Y., Casadesus G., Zhu X. Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A 2008, 105:19318-19323.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
Casadesus, G.7
Zhu, X.8
-
55
-
-
84858018995
-
The dying of the light: mitochondrial failure in Alzheimer's disease
-
Young-Collier K.J., McArdle M., Bennett J.P. The dying of the light: mitochondrial failure in Alzheimer's disease. J Alzheimers Dis 2012, 28:771-781.
-
(2012)
J Alzheimers Dis
, vol.28
, pp. 771-781
-
-
Young-Collier, K.J.1
McArdle, M.2
Bennett, J.P.3
-
56
-
-
84878938660
-
Lipid transport between the endoplasmic reticulum and mitochondria
-
Flis V.V., Daum G. Lipid transport between the endoplasmic reticulum and mitochondria. Cold Spring Harb Perspect Biol 2013, 5:a013235.
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
, pp. a013235
-
-
Flis, V.V.1
Daum, G.2
-
57
-
-
21744445061
-
Bridging gaps in phospholipid transport
-
Voelker D.R. Bridging gaps in phospholipid transport. Trends Biochem Sci 2005, 30:396-404.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 396-404
-
-
Voelker, D.R.1
-
58
-
-
0034795651
-
Acyl-coenzyme A:cholesterol acyltransferase modulates the generation of the amyloid β-peptide
-
Puglielli L., Konopka G., Pack-Chung E., Ingano L.A., Berezovska O., Hyman B.T., Chang T.Y., Tanzi R.E., Kovacs D.M. Acyl-coenzyme A:cholesterol acyltransferase modulates the generation of the amyloid β-peptide. Nat Cell Biol 2001, 3:905-912.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 905-912
-
-
Puglielli, L.1
Konopka, G.2
Pack-Chung, E.3
Ingano, L.A.4
Berezovska, O.5
Hyman, B.T.6
Chang, T.Y.7
Tanzi, R.E.8
Kovacs, D.M.9
-
59
-
-
0042972934
-
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages
-
Feng B., Yao P.M., Li Y., Devlin C.M., Zhang D., Harding H.P., Sweeney M., Rong J.X., Kuriakose G., Fisher E.A., et al. The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages. Nat Cell Biol 2003, 5:781-792.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 781-792
-
-
Feng, B.1
Yao, P.M.2
Li, Y.3
Devlin, C.M.4
Zhang, D.5
Harding, H.P.6
Sweeney, M.7
Rong, J.X.8
Kuriakose, G.9
Fisher, E.A.10
-
60
-
-
33847732649
-
Ultrastructural localization of intraneuronal Aβ-peptide in Alzheimer disease brains
-
Gómez-Ramos P., Asunción Morán M. Ultrastructural localization of intraneuronal Aβ-peptide in Alzheimer disease brains. J Alzheimers Dis 2007, 11:53-59.
-
(2007)
J Alzheimers Dis
, vol.11
, pp. 53-59
-
-
Gómez-Ramos, P.1
Asunción Morán, M.2
-
61
-
-
74949103451
-
Altered cholesterol ester cycle in skin fibroblasts from patients with Alzheimer's disease
-
Pani A., Dessì S., Diaz G., La Colla P., Abete C., Mulas C., Angius F., Cannas M.D., Orru C.D., Cocco P.L., et al. Altered cholesterol ester cycle in skin fibroblasts from patients with Alzheimer's disease. J Alzheimers Dis 2009, 18:829-841.
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 829-841
-
-
Pani, A.1
Dessì, S.2
Diaz, G.3
La Colla, P.4
Abete, C.5
Mulas, C.6
Angius, F.7
Cannas, M.D.8
Orru, C.D.9
Cocco, P.L.10
-
62
-
-
16544376730
-
Role of acyl-coenzyme A:cholesterol acyltransferase activity in the processing of the amyloid precursor protein
-
Puglielli L., Ellis B.C., Ingano L.A., Kovacs D.M. Role of acyl-coenzyme A:cholesterol acyltransferase activity in the processing of the amyloid precursor protein. J Mol Neurosci 2004, 24:93-96.
-
(2004)
J Mol Neurosci
, vol.24
, pp. 93-96
-
-
Puglielli, L.1
Ellis, B.C.2
Ingano, L.A.3
Kovacs, D.M.4
-
63
-
-
84955350049
-
ApoE4 upregulates the activity of mitochondria-associated ER membranes
-
Tambini M.D., Pera M., Kanter E., Yang H., Guardia-Laguarta C., Holtzman D., Sulzer D., Area-Gomez E., Schon E.A. ApoE4 upregulates the activity of mitochondria-associated ER membranes. EMBO Rep 2016, 17:27-36.
-
(2016)
EMBO Rep
, vol.17
, pp. 27-36
-
-
Tambini, M.D.1
Pera, M.2
Kanter, E.3
Yang, H.4
Guardia-Laguarta, C.5
Holtzman, D.6
Sulzer, D.7
Area-Gomez, E.8
Schon, E.A.9
-
64
-
-
0037853140
-
Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization
-
Heeren J., Grewal T., Laatsch A., Rottke D., Rinninger F., Enrich C., Beisiegel U. Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization. J Biol Chem 2003, 278:14370-14378.
-
(2003)
J Biol Chem
, vol.278
, pp. 14370-14378
-
-
Heeren, J.1
Grewal, T.2
Laatsch, A.3
Rottke, D.4
Rinninger, F.5
Enrich, C.6
Beisiegel, U.7
-
65
-
-
11244275436
-
Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation
-
Heeren J., Grewal T., Laatsch A., Becker N., Rinninger F., Rye K.-A., Beisiegel U. Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation. J Biol Chem 2004, 279:55483-55492.
-
(2004)
J Biol Chem
, vol.279
, pp. 55483-55492
-
-
Heeren, J.1
Grewal, T.2
Laatsch, A.3
Becker, N.4
Rinninger, F.5
Rye, K.-A.6
Beisiegel, U.7
-
66
-
-
38549141572
-
Cellular cholesterol trafficking and compartmentalization
-
Ikonen E. Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol 2008, 9:125-138.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 125-138
-
-
Ikonen, E.1
-
67
-
-
77953271492
-
Cholesterol-related genes in Alzheimer's disease
-
Wollmer M.A. Cholesterol-related genes in Alzheimer's disease. Biochim Biophys Acta 2010, 1801:762-773.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 762-773
-
-
Wollmer, M.A.1
-
68
-
-
84929432198
-
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
-
Steinberg S., Stefansson H., Jonsson T., Johannsdottir H., Ingason A., Helgason H., Sulem P., Magnusson O.T., Gudjonsson S.A., Unnsteinsdottir U., et al. Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease. Nat Genet 2015, 47:445-447.
-
(2015)
Nat Genet
, vol.47
, pp. 445-447
-
-
Steinberg, S.1
Stefansson, H.2
Jonsson, T.3
Johannsdottir, H.4
Ingason, A.5
Helgason, H.6
Sulem, P.7
Magnusson, O.T.8
Gudjonsson, S.A.9
Unnsteinsdottir, U.10
-
69
-
-
0345791510
-
Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein
-
Abe-Dohmae S., Ikeda Y., Matsuo M., Hayashi M., Okuhira K.-i., Ueda K., Yokoyama S. Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein. J Biol Chem 2004, 279:604-611.
-
(2004)
J Biol Chem
, vol.279
, pp. 604-611
-
-
Abe-Dohmae, S.1
Ikeda, Y.2
Matsuo, M.3
Hayashi, M.4
Okuhira, K.-I.5
Ueda, K.6
Yokoyama, S.7
-
71
-
-
75649135280
-
Neuropathology of Alzheimer's disease
-
Perl D.P. Neuropathology of Alzheimer's disease. Mt Sinai J Med 2010, 77:32-42.
-
(2010)
Mt Sinai J Med
, vol.77
, pp. 32-42
-
-
Perl, D.P.1
-
72
-
-
0022801449
-
Three-dimensional observation of intracellular membranous structures in dog heart muscle cells by scanning electron microscopy
-
Yoshikane H., Nihei T., Moriyama K. Three-dimensional observation of intracellular membranous structures in dog heart muscle cells by scanning electron microscopy. J Submicrosc Cytol 1986, 18:629-636.
-
(1986)
J Submicrosc Cytol
, vol.18
, pp. 629-636
-
-
Yoshikane, H.1
Nihei, T.2
Moriyama, K.3
|