MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4

Aging

Volumn 8, Issue 3, 2016, Pages 484-505

  Lang, Alexander ^a   Grether Beck, Susanne ^b   Singh, Madhurendra ^a   Kuck, Fabian ^a   Jakob, Sascha ^b   Kefalas, Andreas ^a   Altinoluk Hambüchen, Simone ^a   Graffmann, Nina ^c   Schneider, Maren ^b   Lindecke, Antje ^d   Brenden, Heidi ^b   Felsner, Ingo ^b   Ezzahoini, Hakima ^a   Marini, Alessandra ^b   Weinhold, Sandra ^c   Vierkötter, Andrea ^b   Tigges, Julia ^b   Schmidt, Stephan ^a   Stühler, Kai ^a   Köhrer, Karl ^d   Uhrberg, Markus ^c   Haendeler, Judith ^b   Krutmann, Jean ^b,e   Piekorz, Roland P ^a   more..

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b IUF LEIBNIZ RESEARCH INSTITUTE FOR ENVIRONMENTAL MEDICINE   (Germany)

^c Institut für Transplantationsdiagnostik und Zelltherapeutika ITZ   (Germany)

^d Biologisch Medizinisches Forschungszentrum   (Germany)

^e HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

MicroRNA 15b miR 15b; Nuclear encoded mitochondrial genes; Photoaging; Reactive oxygen species ROS; Senescence; Senescence associated secretory phenotype SASP; SIRT4 Sirtuin 4; Skin

Indexed keywords

MICRORNA; MIRN15 MICRORNA, HUMAN; MITOCHONDRIAL PROTEIN; REACTIVE OXYGEN METABOLITE; SIRT4 PROTEIN, HUMAN; SIRTUIN;

CELL AGING; CELL CULTURE; CUTANEOUS PARAMETERS; FIBROBLAST; GAMMA RADIATION; HUMAN; MALE; METABOLISM; MITOCHONDRION; PHYSIOLOGY; RADIATION RESPONSE; ULTRAVIOLET RADIATION;

CELL AGING; CELLS, CULTURED; FIBROBLASTS; GAMMA RAYS; HUMANS; MALE; MICRORNAS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; REACTIVE OXYGEN SPECIES; SIRTUINS; SKIN AGING; ULTRAVIOLET RAYS;

EID: 84969703233     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100905     Document Type: Article

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