Bap1 is a bona fide tumor suppressor: Genetic evidence from mouse models carrying heterozygous germline Bap1 mutations

Cancer Research

Volumn 76, Issue 9, 2016, Pages 2836-2844

  Kadariya, Yuwaraj ^a   Cheung, Mitchell ^a   Xu, Jinfei ^a,c   Pei, Jianming ^a   Sementino, Eleonora ^a   Menges, Craig W ^a   Cai, Kathy Q ^a   Rauscher, Frank J ^b   Klein Szanto, Andres J ^a   Testa, Joseph R ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b WISTAR INSTITUTE   (United States)

^c Merck Sharp and Dhome   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAP1 GENE; BREAST CARCINOMA; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GERMLINE MUTATION; HETEROZYGOSITY; LUNG CARCINOMA; MESOTHELIOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEX CORD TUMOR; SPINDLE CELL CARCINOMA; TUMOR SUPPRESSOR GENE; WILD TYPE; ANIMAL; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE MODEL; GENE TARGETING; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HEREDITARY TUMOR SYNDROME; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LASER CAPTURE MICRODISSECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BAP1 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN THIOLESTERASE;

ANIMALS; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE MODELS, ANIMAL; GENE KNOCK-IN TECHNIQUES; GENES, TUMOR SUPPRESSOR; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GERM-LINE MUTATION; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MICE; MICE, KNOCKOUT; NEOPLASTIC SYNDROMES, HEREDITARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN THIOLESTERASE;

EID: 84969597427     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-3371     Document Type: Article

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