Plasmid-mediated colistin resistance: An additional antibiotic resistance menace

Clinical Microbiology and Infection

Volumn 22, Issue 5, 2016, Pages 398-400

  Nordmann, P ^a,b   Poirel, L ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Colistin; Enterobactericeae; MCR 1; Polymyxin B; Polymyxins

Indexed keywords

CEPHALOSPORINASE; COLISTIN; ETHANOLAMINE PHOSPHOTRANSFERASE; FLORFENICOL; GROWTH PROMOTOR; MOBILE COLISTIN RESISTANCE 1 PROTEIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIUM ISOLATE; BOVINE; CHICKEN; EDITORIAL; ESCHERICHIA COLI; GENE INSERTION SEQUENCE; GENETIC ASSOCIATION; HUMAN; NONHUMAN; PASTEURELLA MULTOCIDA; PIG; PLASMID; PRIORITY JOURNAL; BACTERIAL INFECTIONS; HORIZONTAL GENE TRANSFER; INTERSPERSED REPEAT; MICROBIOLOGY;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; COLISTIN; DRUG RESISTANCE, BACTERIAL; GENE TRANSFER, HORIZONTAL; HUMANS; INTERSPERSED REPETITIVE SEQUENCES; PLASMIDS;

EID: 84969512848     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2016.03.009     Document Type: Editorial

References (7)

1. Falagas M.E., Rafailidis P.I., Matthaiou D.K. Resistance to polymyxins: mechanisms, frequency and treatment options. Drug Resist Update 2010, 13:132-138.
2. Liu Y.Y., Wang Y., Walsh T.R., Yi L.-X., Zang R., Spencer J., et al. Emergence of plasmid-mediated colistin-resistance mechanism MCR-1 in animals and human beings in China: a microbiological study and molecular biology study. Lancet Infect Dis 2016, pii:S1473-3099(15)00424-7i.
3. Poirel L., Kieffer N., Liassine N., Than D., Nordmann P. Plasmid-encoded carbapenem and colistin resistance in a clinical isolate of Escherichia coli. Lancet Infect Dis 2016, 10.1016/S1473-3099(16)00006-2.
4. Falgenhauer L., Waezsada S.-E., Yao Y., Imirzalioglu C., Käsbohrer A., Roesler U. Colistin resistance gene mcr-1 in extended-spectrum β-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany. Lancet Infect Dis 2016, 10.1016/S1473-3099.
5. Du H., Chen L., Tan T.W., Kreiswirth B.N. Emergence of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae. Lancet Infect Dis 2016, 10.1016/S1473-3099(16)00056-6.
6. Nordmann P., Lienhard R., Kieffer N., Clerc O., Poirel L. Plasmid mediated colistin resistance in Escherichia coli in bacteremia in Switzerland. Clin Infect Dis 2016, pii: ciw124.
7. Heaenni M., Poirel L., Kieffer N., Châtre P., Saras E., Métayer V., et al. Co-occurrence of extended-spectrum ß-lactamase and MCR-1 encoding genes on plasmids. Lancet Infect Dis 2016, 10.1016/S1473-3099(16)00007-4.