B cell depletion therapy upregulates Dkk-1 skin expression in patients with systemic sclerosis: Association with enhanced resolution of skin fibrosis

Arthritis Research and Therapy

Volumn 18, Issue 1, 2016, Pages

  Daoussis, Dimitrios ^a   Tsamandas, Athanassios ^a   Antonopoulos, Ioannis ^a   Filippopoulou, Alexandra ^a   Papachristou, Dionysios J ^a   Papachristou, Nicholaos I ^a   Andonopoulos, Andrew P ^a   Liossis, Stamatis Nick ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

B cell depletion; Dickkopf 1; Dkk 1; Fibrosis; Rituximab; Scleroderma; Skin; Systemic sclerosis; TGF

Indexed keywords

DICKKOPF 1 PROTEIN; RITUXIMAB; TRANSFORMING GROWTH FACTOR BETA; DKK1 PROTEIN, HUMAN; IMMUNOLOGIC FACTOR; SIGNAL PEPTIDE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DKK1 GENE; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; GENE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HUMORAL IMMUNE DEFICIENCY; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; SKIN BIOPSY; SKIN FIBROSIS; SYSTEMIC SCLEROSIS; UPREGULATION; ADULT; BIOSYNTHESIS; DRUG EFFECTS; FEMALE; FIBROBLAST; FIBROSIS; IMMUNOASSAY; LYMPHOCYTE DEPLETION; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL; SCLERODERMA, SYSTEMIC; SKIN;

ADULT; FEMALE; FIBROBLASTS; FIBROSIS; HUMANS; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC FACTORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE DEPLETION; MALE; MIDDLE AGED; RITUXIMAB; SCLERODERMA, SYSTEMIC; SKIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84969509044     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-016-1017-y     Document Type: Article

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