Studies on the metabolism and toxicological detection of the new psychoactive designer drug 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) in human and rat urine using GC-MS, LC-MSn, and LC-HR-MS/MS

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 22, 2021, Pages

  Caspar, Achim T ^a   Helfer, Andreas G ^a   Michely, Julian A ^a   Auwärter, Volker ^b   Brandt, Simon D ^c   Meyer, Markus R ^a,d   Maurer, Hans H ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

25I NBOMe; Cytochrome P450; Designer drugs; LC HR MS MS; LC MSn; Metabolism

Indexed keywords

BIOMOLECULES; DRUG INTERACTIONS; HYDROXYLATION; METABOLISM; RATS; SCREENING;

25I-NBOME; CYTOCHROME P450; DESIGNER DRUGS; HUMAN URINE SAMPLES; LC-HR-MS/MS; PSYCHOACTIVE DESIGNER DRUG; SCREENING APPROACHES; TOXICOLOGICAL ANALYSIS;

METABOLITES;

2-(4-IODO-2,5-DIMETHOXYPHENYL)-N-(2-METHOXYBENZYL)ETHANAMINE; DESIGNER DRUG; HOMOVERATRYLAMINE; PSYCHOTROPIC AGENT;

ANALOGS AND DERIVATIVES; ANIMAL; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MASS FRAGMENTOGRAPHY; PROCEDURES; RAT; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE; TANDEM MASS SPECTROMETRY; TOXICITY TESTING; URINALYSIS; URINE; WISTAR RAT;

ANIMALS; CHROMATOGRAPHY, LIQUID; DESIGNER DRUGS; DIMETHOXYPHENYLETHYLAMINE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MALE; PSYCHOTROPIC DRUGS; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY; TOXICITY TESTS; URINALYSIS;

EID: 84969406071     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-8828-6     Document Type: Article

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