The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation

Acta neuropathologica communications

Volumn 3, Issue , 2015, Pages 89-

  Rutten, Julie W ^a   Klever, Roselin R ^a   Hegeman, Ingrid M ^a   Poole, Dana S ^a   Dauwerse, Hans G ^a   Broos, Ludo A M ^a   Breukel, Cor ^a   Aartsma Rus, Annemieke M ^a   Verbeek, J Sjef ^a   van der Weerd, Louise ^a   van Duinen, Sjoerd G ^a   van den Maagdenberg, Arn M J M ^a   Lesnik Oberstein, Saskia A J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NOTCH RECEPTOR; NOTCH3 PROTEIN, HUMAN; NOTCH3 RECEPTOR;

AGE; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; C57BL MOUSE; CADASIL; DISEASE MODEL; DNA MUTATIONAL ANALYSIS; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE; MUTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; TRANSGENIC MOUSE;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CADASIL; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION REGULATION; HUMANS; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MUTATION; RECEPTOR, NOTCH3; RECEPTORS, NOTCH; RNA, MESSENGER;

EID: 84969171492     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-015-0268-1     Document Type: Article

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