Dissecting negative symptoms of schizophrenia: History, assessment, pathophysiological mechanisms and treatment

Schizophrenia Research

Volumn 186, Issue , 2017, Pages 1-2

  Galderisi, Silvana ^a   Färden, Ann ^b,c   Kaiser, Stefan ^d  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; NEUROLEPTIC AGENT;

ANHEDONIA; ANTISOCIAL BEHAVIOR; APATHY; BRIEF NEGATIVE SYMPTOM SCALE; CLINICAL ASSESSMENT; CLINICAL ASSESSMENT INTERVIEW FOR NEGATIVE SYMPTOMS; DEFICIT SCHIZOPHRENIA; HUMAN; NEGATIVE SYNDROME; NOTE; PATHOPHYSIOLOGY; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; PROGNOSIS; SCALE FOR THE ASSESSMENT OF NEGATIVE SYMPTOMS; SCHEDULE FOR THE DEFICIT SYNDROME; SCHIZOPHRENIA; SCHIZOPHRENIA ASSESSMENT; HISTORY; PSYCHOLOGY;

HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 84966700352     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2016.04.046     Document Type: Note

References (17)

1. Ahmed, A.O., Strauss, G.P., Buchanan, R.W., Kirkpatrick, B., Carpenter, W.T., Are negative symptoms dimensional or categorical? Detection and validation of deficit schizophrenia with taxometric and latent variable mixture models. Schizophr. Bull. 41:4 (2015), 879–891.
2. Blanchard, J.J., Cohen, A.S., The structure of negative symptoms within schizophrenia: implications for assessment. Schizophr. Bull. 32:2 (2006), 238–245.
3. Bleuler, E., Dementia Praecox, or the Group of Schizophrenias. 1950, International Universities Press, New York.
4. Buchanan, R.W., Persistent negative symptoms in schizophrenia: an overview. Schizophr. Bull. 33:4 (2007), 1013–1022.
5. Carpenter, W.T. Jr., Psychopathology and common sense. Biol. Psychiatry 29:8 (1991), 735–737.
6. Carpenter, W.T. Jr., Heinrichs, D.W., Wagman, A.M., Deficit and nondeficit forms of schizophrenia: the concept. Am. J. Psychiatry 145:5 (1988), 578–583.
7. Iranpour, N., Zandifar, A., Farokhnia, M., Goguol, A., Yekehtaz, H., Khodaie-Ardakani, M.R., Salehi, B., Esalatmanesh, S., Zeionoddini, A., Mohammadinejad, P., Zeinoddini, A., Akhondzadeh, S., The effects of pioglitazone adjuvant therapy on negative symptoms of patients with chronic schizophrenia: a double-blind and placebo-controlled trial. Hum. Psychopharmacol. 31:2 (2016), 103–112.
8. Kirkpatrick, B., Buchanan, R.W., McKenney, P.D., Alphs, L.D., Carpenter, W.T. Jr., The schedule for the deficit syndrome: an instrument for research in schizophrenia. Psychiatry Res. 30:2 (1989), 119–123.
9. Kirkpatrick, B., Fenton, W.S., Carpenter, W.T. Jr., Marder, S.R., The NIMH-MATRICS consensus statement on negative symptoms. Schizophr. Bull. 32:2 (2006), 214–219.
10. Kirkpatrick, B., Strauss, G.P., Nguyen, L., Fischer, B.A., Daniel, D.G., Cienfuegos, A., Marder, S.R., The brief negative symptom scale: psychometric properties. Schizophr. Bull. 37:2 (2011), 300–305.
11. Kraepelin, E., Dementia-Praecox and Paraphrenia. Huntington, New York. 1919.
12. Kring, A.M., Gur, R.E., Blanchard, J.J., Horan, W.P., Reise, S.P., The clinical assessment interview for negative symptoms (CAINS): final development and validation. Am. J. Psychiatry 170:2 (2013), 165–172.
13. McKechanie, A.G., Moorhead, T.W., Stanfield, A.C., Whalley, H.C., Johnstone, E.C., Lawrie, S.M., Owens, D.G., Negative symptoms and longitudinal grey matter tissue loss in adolescents at risk of psychosis: preliminary findings from a 6-year follow-up study. Br. J. Psychiatry, 2015, 10.1192/bjp.bp.114.154526 published online December 3, 2015.
14. Sergi, M.J., Rassovsky, Y., Widmark, C., Reist, C., Erhart, S., Braff, D.L., Marder, S.R., Green, M.F., Social cognition in schizophrenia: relationships with neurocognition and negative symptoms. Schizophr. Res. 90:1–3 (2007), 316–324.
15. Tandon, R., Greden, J.F., Negative symptoms of schizophrenia: need for conceptual clarity. Biol. Psychiatry 30:4 (1991), 321–325.
16. Tandon, R., Goldman, R., Dequardo, J.R., Goldman, M., Perez, M., Jibson, M., Positive and negative symptoms covary during clozapine treatment in schizophrenia. J. Psychiatry Res. 27:4 (1993), 341–347.
17. Treadway, M.T., Peterman, J.S., Zald, D.H., Park, S., Impaired effort allocation in patients with schizophrenia. Schizophr. Res. 161:2–3 (2015), 382–385.